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Sample search results for: a-stereogenic ketone moiety

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1 -Chlorination of Ketones Using p-Toluenesulfonyl Chloride
 

Summary:  -Chlorination of Ketones Using p-Toluenesulfonyl Chloride Kay M. Brummond* and Kirsten D. Gesenberg... of ketones with lithium diisopropylamide followed by p-toluenesulfonyl chloride gives -chloroketones in good... this transformation. Chlorination of ketones at the -position has classically involved acid or light initiated

  

Source: Brummond, Kay M. - Department of Chemistry, University of Pittsburgh

 

Collection: Chemistry

 
2 Application of Aryloximes as Solid-Phase Ketone Linkers
 

Summary:  Application of Aryloximes as Solid-Phase Ketone Linkers Salvatore D. Lepore and Michael R. Wiley... September 16, 2002 ABSTRACT In both solution and the solid phase, a variety of ketone oxime anions have been... the corresponding ketones. Suzuki and amide coupling reactions were also successfully performed on two resin

  

Source: Lepore, Salvatore D. - Department of Chemistry and Biochemistry, Florida Atlantic University

 

Collection: Chemistry

 
3 ORIGINAL PAPER Reactivity versus steric effects in fluorinated ketones
 

Summary:  the activity against human carboxylesterase 1. The intrinsic reactivity of the ketone moiety is determined from... influence of substituents attached to the ketone moiety on the chemical reactivity toward formation... carboxylesterase 1 (hCE1). The reactivity properties of the fluorinated ...

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
4 Geometrical Effects on Intramolecular Quenching of Aromatic Ketone (,*) Triplets by Remote Phenolic Hydrogen Abstraction
 

Summary:  Geometrical Effects on Intramolecular Quenching of Aromatic Ketone (,*) Triplets by Remote Phenolic... techniques. The compounds are structured with a p- or m-phenolic moiety attached via a m- or p... ketones vary with the positions of attachment (meta or para) of the oxyethyl spacer to the carbonyl

  

Source: Leigh, William J. - Department of Chemistry, McMaster University

 

Collection: Chemistry

 
5 Tetrahedron Letters, V01.72, No.379 PP 3565 -3568, 1981 Printed in Great Britain
 

Summary:  : Acetylenic alcohols, obtained in high yield from 3,3_ethylenedioxybutyne with cyclic ketones, may annelation... the condensation of lithium acetylides of 3,3_diethoxypropyne and 3,3- ethylenedioxybutyne with selected ketones... of these antineoplastic agents from a cornnon synthetic inter- mediate. R.M. Jacobson' Condensation of cyclic ...

  

Source: Williams, David R. - Department of Chemistry, Indiana University

 

Collection: Chemistry

 
6 Strategy for the Preparation of Allenes From ,-Unsaturated and Saturated Ketones via Enol Phosphates
 

Summary:  1 Strategy for the Preparation of Allenes From ,-Unsaturated and Saturated Ketones via Enol... University Morgantown, West Virginia 26506 The versatility and synthetic utility of the allene moiety... accessible by other synthetic methods.1,2 In addition, the allene moiety can be transformed into a variety

  

Source: Brummond, Kay M. - Department of Chemistry, University of Pittsburgh

 

Collection: Chemistry

 
7 Enantioselective Synthesis of Second-Generation Light-Driven
 

Summary:  ) b) #12;136 Chapter 4 methoxy ketone, in which again the naphthalene moiety is replaced by a xylyl... -driven molecular motors. Two new methods for the preparation of the upper-half ketone precursors are presented... these molecules in their enantiopure form. Emphasis will be on the enantioselective synthesis of the ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
8 ACCOUNT 749 Development of the First Practical Catalyst for the Asymmetric Addition of
 

Summary:  - and Arylzinc Reagents to Ketones CatalyticAsymmetricAlkylationofKetonesJuan M. Betancort, Celina García... to ketones to establish chiral quaternary centers. Such compounds are valuable chiral building blocks... reagents to ketones. The scope of this reaction is outlined, including a tandem ...

  

Source: Walsh, Patrick J. - Department of Chemistry, University of Pennsylvania

 

Collection: Chemistry

 
9 Photoinduced Hydrogen Abstraction from Phenols by Aromatic Ketones. A New Mechanism for Hydrogen Abstraction by
 

Summary:  the results for a series of ketones which contain a para-phenolic moiety attached via a para-oxyethyl linkage... Photoinduced Hydrogen Abstraction from Phenols by Aromatic Ketones. A New Mechanism for Hydrogen... in the rates of bimolecular quenching of the parent methoxy-substituted ketones by p-cresol. ...

  

Source: Leigh, William J. - Department of Chemistry, McMaster University

 

Collection: Chemistry

 
10 A New Chiral Bis(oxazolinylmethyl)amine Ligand for Ru-Catalyzed Asymmetric Transfer Hydrogenation
 

Summary:  )3 for transfer hydrogenation of aryl alkyl ketones. The presence of an NH moiety in the Ru-ambox is important... of Ketones Yutong Jiang, Qiongzhong Jiang, and Xumu Zhang* Department of Chemistry, The PennsylVania State... unfunctionalized ketones to chiral alcohols.1 The reaction uses inexpensive reagents ...

  

Source: Zhang, Xumu - Department of Chemistry, Pennsylvania State University

 

Collection: Chemistry

 
11 Direct and enantioselective -allylation of ketones via singly occupied molecular orbital (SOMO) catalysis
 

Summary:  Direct and enantioselective -allylation of ketones via singly occupied molecular orbital (SOMO... of commercially available allyl silanes. A reasonable latitude in both the ketone and allyl silane components... - none catalysts have been developed that allow cyclic ketones to successfully participate

  

Source: MacMillan, David W. C. - Department of Chemistry, Princeton University

 

Collection: Chemistry

 
12 Use of ab Initio Calculations To Predict the Biological Potency of Carboxylesterase Inhibitors
 

Summary:  that the ketone hydration state was affected by the surrounding chemical moieties and was related to inhibitor... of inhibitors with varying substituents surrounding the ketone moiety. Another theory for the activity of TFK... surrounding the ketone moiety (Tables 1 ...

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
13 A Chemoenzymatic Approach toward the Rapid and Sensitive Detection of O-GlcNAc Posttranslational Modifications
 

Summary:  functionality to O-GlcNAc modified proteins (Figure 1). The ketone moiety has been well... on the substrate tolerance of GalT, which allows for chemoselective installation of an unnatural ketone... chose to append the ketone functionality at the C-2 position of the galactose ring because GalT has been

  

Source: Hsieh-Wilson, Linda - Department of Chemistry, California Institute of Technology

 

Collection: Chemistry

 
14 [Reprinted from the .Journalof Organic Chemistry'.{0. i]r77 ( 1975).l Copvright 19?5by the American Chemical Societvand reprinted bv permissionof the copyright owner.
 

Summary:  to Methyl Ketones by Jones Reagent Is Catalyzed,by Mercury(Il)t Harold R. Rogers, Joseph X. McDermott,2... a catalytic quantity of mercury(II) affords good yields (>lO"t") of the corresponding methyl ketones. Similar... olefins, mixtures of ketones are produced. The Wacker process for oxidation of olefins to ...

  

Source: Prentiss, Mara - Department of Physics, Harvard University

 

Collection: Physics

 
15 Detection Via Laser Desorption and Mass Spectrometry of Multiplex Electrophore-labeled
 

Summary:  as a ketone when heated, due to a thermal retro-aldol reaction. The multiplex electrophore-labeled albumin... the released ketone electrophores)/off-line gas chromatography/electron capture-mass spectrometry... is to stabilize this site on the tetrafluorobenzyl moiety against chemical substitu- tion during synthesis, since

  

Source: Church, George M. - Wyss Institute for Biologically Inspired Engineering & Department of Genetics, Harvard University

 

Collection: Biotechnology

 
16 J. Chem. Soc., Perkin Trans. 1, 1998 843 Highly stereoselective synthesis of spiro--methylene--butyro-
 

Summary:  to chiral ketones. We find that -hydroxy substitution also plays a similar role. Whereas the addition... of a Reformatsky reagent to unsubstituted steroidal ketones does not yield the desired products, -hydroxy... - selectivity. The -methylene- -butyrolactone moiety has been synthesized at several positions on the steroid

  

Source: Desai, Umesh R - Department of Medicinal Chemistry, Virginia Commonwealth University

 

Collection: Biology and Medicine

 
17 2166 J. Am. Chem. SOC.1995,117, 2166-2178 Mechanism of Lithium Dialkylamide-Mediated Ketone and
 

Summary:  is two-fold:l3 (1) The imine moiety contrasts with the analogous ketones by affording an N... between ketones and imines is the steri- cally demanding imine N-alkyl moiety. We first had to determine... 2166 J. Am. Chem. SOC.1995,117, 2166-2178 Mechanism of Lithium Dialkylamide-Mediated ...

  

Source: Collum, David B. - Department of Chemistry and Chemical Biology, Cornell University

 

Collection: Chemistry

 
18 Michael-Stork Addition of Cyclopentyl Enamine to Allenyl Ketones and Esters
 

Summary:  Michael-Stork Addition of Cyclopentyl Enamine to Allenyl Ketones and Esters Maximilian A. Silvestri... of a Michael-Stork enamine addition to allenyl esters and ketones. Studies reveal that 2 equivalents of enamine... are required for optimal yields. In the case of an allenyl methyl ketone, cyclopentyl enamine addition led to 8

  

Source: Lepore, Salvatore D. - Department of Chemistry and Biochemistry, Florida Atlantic University

 

Collection: Chemistry

 
19 Lithium Hexamethyldisilazide-Mediated Enolizations: Influence of Triethylamine on E/Z Selectivities and Enolate
 

Summary:  )/toluene is shown to enolize acyclic ketones and esters rapidly and with high E/Z selectivity. Mechanistic studies... HMDS- mediated ketone enolizations (eq 1).3 We found that enolization of ketone 1 in Et3N/toluene3a is >100 times... herein LiHMDS/Et3N-mediated enolizations of acyclic ketones. The ...

  

Source: Collum, David B. - Department of Chemistry and Chemical Biology, Cornell University

 

Collection: Chemistry

 
20 Synthesis of the C3-C18 Fragment of Amphidinolides G and H
 

Summary:  by lithiation of iodide 4 and trapping of the anion with amide 5. The allylic epoxide moiety could... efforts toward the C10-C18 fragment 4 began with ketone 7, which was prepared from (-)- pseudoephedrine... propionamide under the conditions devel- oped by Myers8 (Scheme 1). Ketone 7 was further elaborated

  

Source: Crews, Craig M. - Department of Molecular Biophysics and Biochemistry, Yale University

 

Collection: Chemistry ; Biology and Medicine


Page:   2  3  4  5 
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21 Ketone Enolization by Lithium Hexamethyldisilazide: Structural and Rate Studies of the Accelerating Effects of
 

Summary:  Ketone Enolization by Lithium Hexamethyldisilazide: Structural and Rate Studies of the Accelerating... are described. NMR spectroscopic studies of LiHMDS/ketone mixtures in toluene reveal the ketone-complexed cyclic... dimer (TMS2NLi)2(ketone). Rate studies using in situ IR spectroscopy show the enolization ...

  

Source: Collum, David B. - Department of Chemistry and Chemical Biology, Cornell University

 

Collection: Chemistry

 
22 Transposing Molecular Fluorescent Switches into the Near-IR: Development of Luminogenic Reporter Substrates for Redox Metabolism
 

Summary:  510 nm) upon enzymatic reduction of the corresponding nonfluorescent ketone substrate. The importance... is whether the ketone/alcohol transformation would effect the significant change in ET efficiency necessary... - system crossing (from singlet to triplet state), such as the ketone, would influence the energy transfer

  

Source: Turro, Nicholas J. - Department of Chemistry, Columbia University

 

Collection: Chemistry

 
23 Use of Classical and 3-D QSAR to Examine the Hydration State of Juvenile Hormone Esterase Inhibitors
 

Summary:  suggests that inhibition occurs through the ketone, not the hydrated gem-diol. Some studies have stated... that the ketone is the inhibitor, while others have reported the gem-diol as the active form. Using juvenile... - bitor potency upon log P as well as the limitations of sterically unfavorable substituents. The ketone

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
24 New Contact Sex Pheromone Components of the German Cockroach, Blattella germanica, Predicted from the Proposed
 

Summary:  Lafferty rearrangements of alpha-methyl ketone and 1,1-dimethylhydrazone moieties, ­CH2­CH(CH3)­ CO­CH3 and ­CH=N­N(CH3... ,11-dimethylheptacosane, respectively. The C29-dimethyl ketone is thought to be further metabo- lized to two less abundant... ketone . Alcohol . Aldehyde Introduction Sex pheromones ...

  

Source: Schal, Coby - Department of Entomology, North Carolina State University

 

Collection: Biology and Medicine

 
25 Exploring the O-GlcNAc proteome: Direct identification of O-GlcNAc-modified
 

Summary:  CHEMISTRYBIOCHEMISTRY #12;labeled with the ketone-biotin tag (m z 787.86). Notably, the ketone-biotin moiety produced... indication of an O-GlcNAc containing peptide. Specifi- cally, predominant loss of the ketone-biotin moiety... of peaks in this region contained the ...

  

Source: Hsieh-Wilson, Linda - Department of Chemistry, California Institute of Technology

 

Collection: Chemistry

 
26 Published: March 18, 2011 r 2011 American Chemical Society 5194 dx.doi.org/10.1021/ja200009c |J. Am. Chem. Soc. 2011, 133, 51945197
 

Summary:  acetate esters,5 methyl aryl ketones,2a,3a,c,5a,6 acetonitrile,7 and dimethylacetamide2b with unbiased... ketone substrate, still represents a significant challenge that has not been addressed to date.8 Key... obstacles to the selective monoarylation of acetone incl- ude the fact that the R-aryl methyl ketone

  

Source: Stradiotto, Mark - Department of Chemistry, Dalhousie University

 

Collection: Chemistry

 
27 BrooRGANrccHEMTSTRY17, 4l-_52(1989) EnzymaticBaeyer-VilligerTypeOxidationsof Ketones
 

Summary:  of the dioxygen being reducedto hydrogen peroxide. That is, oxygen insertion into the ketone moiety would... BrooRGANrccHEMTSTRY17, 4l-_52(1989) EnzymaticBaeyer-VilligerTypeOxidationsof Ketones Catalyzedby... -containingNADPH-dependent monooxygenasethat utilizesdioxygen to convert cy- clic ketones into ...

  

Source: Prentiss, Mara - Department of Physics, Harvard University

 

Collection: Physics

 
28 Synthesis and Reactivity of [(DMSC)Ti(2-OCAr2)L2] Complexes (DMSC ) Dimethylsilyl-Bridged
 

Summary:  of the ketone moiety of 4 by 2,2-bipyridine proceeds more efficiently than reaction of 4 with (p-MeC6H4)2CO... products. (20) More facile substitution of 2-ketone complexes bearing alkyl or aryl moieties in comparison... ). Subsequent hydride migration to a metal- bound ketone affords the ...

  

Source: Parkin, Sean - X-Ray Laboratory & Department of Chemistry, University of Kentucky

 

Collection: Chemistry

 
29 Direct Identification of Nonreducing GlcNAc Residues on N-Glycans of Glycoproteins Using a Novel Chemoenzymatic Method
 

Summary:  , a galactose moiety that has a ketone substitution at the C2 position of the galactose ring (21... of a glycoprotein. The ketone moiety at the C2 position of galactose Figure 4. Detection of GlcNAc glycosylated... NAc) (15) or a ketone moiety (21). (B) The C2 ...

  

Source: Hsieh-Wilson, Linda - Department of Chemistry, California Institute of Technology

 

Collection: Chemistry

 
30 Lithium Ephedrate-Mediated Addition of a Lithium Acetylide to a Ketone: Solution Structures and Relative Reactivities of Mixed
 

Summary:  °C. Moreover, ketones such as PhCOCF3 void of the o-NHR moiety afford mediocre selectivities... moiety while the ketone methyl group is situated above the ephedrate chelate with syn... Lithium Ephedrate-Mediated Addition of a Lithium Acetylide to a Ketone: Solution Structures

  

Source: Collum, David B. - Department of Chemistry and Chemical Biology, Cornell University

 

Collection: Chemistry

 
31 Highly Efficient Antibody-Catalyzed Deuteration of Carbonyl Compounds Avidor Shulman,[a]
 

Summary:  deuterium-exchange reactions at the a position of a variety of ketones and aldehydes, including substrates... catalyzes the exchange reaction of a-protons in a variety of ketones and aldehydes. The observed catalytic... , including a variety of functionalized aldehydes or ketones. This study also highlights mechanistic details

  

Source: Keinan, Ehud - Department of Chemistry, Technion, Israel Institute of Technology

 

Collection: Biotechnology ; Chemistry

 
32 Equilibrium 2 H fractionations in organic molecules
 

Summary:  to carbonyl group (Ha) in ketones. H at these positions equilibrates on a timescale of days as a result... . Molecular vibrations for the same ketone molecules are then computed using Density Functional Theory... and computational results for six different straight and branched ketones yields a temperature-dependent linear

  

Source: Goddard III, William A. - Materials and Process Simulation Center & Department of Chemistry, California Institute of Technology; Sessions, Alex L. - Division of Geological and Planetary Sciences, California Institute of Technology

 

Collection: Environmental Sciences and Ecology ; Geosciences ; Materials Science

 
33 Electrophore Mass Tag Dideoxy DNA Sequencing Linxiao Xu, Nanying Bian, Zhixian Wang, Samy Abdel-Baky, Sasi Pillai, Daniel Magiera,
 

Summary:  . This demonstrated that 1e was fully stable to these conditions. Thermal Release of Ketone 1a from Glycol Amide 1e... . The column and detector temperature were both set at 240 °C. Ketone 1a was injected first with the injector... ]6-) amino linker. Thermal Release of Ketones from Electrophore-Labeled Oligonucleotides. Four ...

  

Source: Church, George M. - Wyss Institute for Biologically Inspired Engineering & Department of Genetics, Harvard University

 

Collection: Biotechnology

 
34 162 J. Am. Chem. SOC.1986, 108, 162-169 Thermostable Enzymes in Organic Synthesis. 2. Asymmetric
 

Summary:  Reduction of Ketones with Alcohol Dehydrogenase from Thermoanaerobium brockii Ehud Keinan,*ts Eva K. Hafeli... , Israel. Received October 9, 1984 Abstract: The asymmetric reduction of aliphatic acyclic ketones (C4-Cl0... ethyl, methyl isopropyl,or methyl cyclopropyl ketones) are reduced to R alcohols, whereas the higher

  

Source: Keinan, Ehud - Department of Chemistry, Technion, Israel Institute of Technology

 

Collection: Biotechnology ; Chemistry

 
35 Novel 2-Oxoamide Inhibitors of Human Group IVA Phospholipase A2
 

Summary:  diseases. Arachidonyl trifluoromethyl ketone (AATFK), an arachidonic acid analogue in which the -COOH group... tricarbon- yls5 and trifluoromethyl ketones6 has been studied. Recently, pyrrolidine-based inhibitors... proteases contain an activated carbonyl group, for example, fluorinated ketones11 and R-ketoamides,12

  

Source: Dennis, Edward A. - Department of Chemistry and Biochemistry, University of California at San Diego

 

Collection: Biology and Medicine

 
36 Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to
 

Summary:  agrochemicals. Trifluoromethyl ketone (TFK)-contain- ing compounds with a sulfur atom b to the ketone moiety... the trifluoromethyl ketones (TFKs).11 This moiety was first reported by Brodbeck et al. for use in the inhibition... to the ketone/gem-diol. (D) Putative ...

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
37 10.1021/ol103117j r 2011 American Chemical Society Published on Web 02/16/2011
 

Summary:  with an appended R-pyrone moiety. Its unprecedented carbon skeleton contains two acyl resorcinol motifs typical... .8 Condensation of the corresponding organolithium compound with Weinreb amide 169 gave ketone 17... -type condensation with the anion of 15 to afford aryl benzyl ketone 19. This material underwent cycli- zation upon

  

Source: Trauner, Dirk - Department Chemie, Ludwig Maximilians Universität München

 

Collection: Chemistry

 
38 CHM 7200 Organic Structures and Mechanisms Fall Term 2006 Problem Set 3: This problem set is now available at (www.blackboard.wayne.edu). It will be due
 

Summary:  , 3254.) The illustrated substrates will undergo fragmentation to an olefinic ketone IF the appropriate... of the corresponding syn di-substituted system by employing a participating phenyl-2- (phenylsulfanyl)ethyl moiety

  

Source: Andreana, Peter R. - Department of Chemistry, Wayne State University

 

Collection: Chemistry

 
39 The Development of New Carboxylic Acid-Based MMP Inhibitors Derived from a Cyclohexylglycine Scaffold
 

Summary:  of the MMPs. The majority of inhibitor scaffolds that have been disclosed contain a hydroxamic acid moiety... toward selective MMPIs that contain a carboxylic acid moiety as a zinc binding element and this effort... con- tain a biaryl moiety that inserts into the P10 pocket of MMP enzymes and effectively selects

  

Source: Hudlicky, Tomas - Department of Chemistry, Brock University

 

Collection: Chemistry

 
40 Lithium Diisopropylamide-Mediated Lithiations of Imines: Insights into Highly Structure-Dependent Rates and
 

Summary:  to the ketone CdO moiety.5 Of particular importance, the N-alkyl substituents on imines and lithioimines... -position of the cyclohexyl moiety afford a 60,000-fold range of rates. Detailed rate studies implicate... moiety on the N-alkyl group, (d) the presence of a 2-methyl substituent at the geminal or ...

  

Source: Collum, David B. - Department of Chemistry and Chemical Biology, Cornell University

 

Collection: Chemistry


Page:   1  2  3  4  5 
Page:   1  2  3  4  5 
 
41 Reaction of Ketones with Lithium Hexamethyldisilazide: Competitive Enolizations and 1,2-Additions
 

Summary:  Reaction of Ketones with Lithium Hexamethyldisilazide: Competitive Enolizations and 1,2-Additions... structure [(TMS2NLi)(ketone)- (pyrrolidine)3]q . The partitioning between enolization and 1,2-addition... . Addition of ketone 1 to LiHMDS in either THF or THF/hydrocarbon mixtures at -78 °C was monitored by in situ

  

Source: Collum, David B. - Department of Chemistry and Chemical Biology, Cornell University

 

Collection: Chemistry

 
42 J. Org. Chem. 1990,55, 2927-2938 2927 where, until now, the Pd(I1)-catalyzed oxidation was not
 

Summary:  Reagent for Hydrolysis and Reductive Iodination of Ketals, Acetals, Ketones, and Aldehydes E. Keinan,* D... ) with ketals,acetals,ketones, and aldehydes were explored. The reagent may be used for mild cleavageof ketals... %) of DIS provideclean deprotection of variousketals and acetals to yield ketones and aldehydes

  

Source: Keinan, Ehud - Department of Chemistry, Technion, Israel Institute of Technology

 

Collection: Biotechnology ; Chemistry

 
43 Geometric and solvent effects on intramolecular phenolic hydrogen abstraction by carbonyl n,p*
 

Summary:  to the ketone by a para,para¢- or meta,meta¢-oxyethyl spacer, has been studied in acetonitrile... a coplanar arrangement with the n-orbitals of the carbonyl group. Key words: photochemistry, aromatic ketone... states of most aromatic ketones occurs at rates in excess of 1 × 109 M­1 s­1 in solution, resulting

  

Source: Leigh, William J. - Department of Chemistry, McMaster University

 

Collection: Chemistry

 
44 Femtosecond Chemically Activated Reactions: Concept of Nonstatistical Activation at High Thermal Energies
 

Summary:  the energy is temporally and spatially deposited in one moiety of the molecule. The internally hot radicals... Studied The systems studied here are the family of structures: acetone, CH3COCH3; diethyl ketone, CH3CH2... COCH2CH3; and methyl ethyl ketone, CH3COCH2CH3 (represented at the top of Figure 1), and its R-D and -D

  

Source: Kim, Sang Kyu - Department of Chemistry, Korea Advanced Institute of Science and Technology

 

Collection: Chemistry

 
45 Tetrahedron Letters,Vol.25,No.23,pp 2447-2450,1984 0040-4039/84 $3.00 + -00 Printed in Great Britain 01984 Pergamon Press Ltd.
 

Summary:  moiety.4 Owing to its reductive and epimerizable capacity the acrylate 1 seemed an ideal precursor... conversion to epiisocomene) of ketone 2 which we have prepared in several ways418 and which has been reported... available from ketone 2 by #12;2449 Scheme 1 0 L 96% H2/Pt02 1 0 KH~PP~~I+~--,(cH?)?CCH~~N [CH

  

Source: Hudlicky, Tomas - Department of Chemistry, Brock University

 

Collection: Chemistry

 
46 Tetrahedron Letters Nc. 29, pp 2667 -?6lG. @Pergamon Press Ltd. 1979. Printed ir,Great iir:tair?.
 

Summary:  procedure, namely the Wolff-rearrangement of diazo- ketones, has been reported to give low yields2 (< 10... moiety is available to the carbenoid) in high yields through a controlled decomposition of diazoketones 1... Diazo Chloride Ketone Ester Acid Remarks -02H 81 al00 82 3a, 90 94 directly w 4H from la 3a 70 cl00 94 3

  

Source: Hudlicky, Tomas - Department of Chemistry, Brock University

 

Collection: Chemistry

 
47 Cyanation Reaction Recent Developments in the Catalytic Asymmetric
 

Summary:  , vinyl methyl ketimines 6­8, in which the vinyl moiety is di- or trisubstituted, also gave good results... yet, closely related complexes were used to achieve the cyanation of ketones.[7] Mechanistic studies... are based on their proposed structure for the cyanation of ketones.[7a] Note that in both cases ...

  

Source: Spino, Claude - Département de chimie, Université de Sherbrooke

 

Collection: Chemistry

 
48 C-F Bond Activation by Aryl Carbocations: Conclusive Intramolecular Fluoride Shifts between
 

Summary:  that shuts down competing chain pathways.8 Heating (40 °C) of 1a in C6F6 instead gave ketone 6 in 55% (entry... the ArCF3 moiety is fairly stable to hydrolysis (hot concentrated H2SO4 hydrolyzes ArCF3 over the course... of several hours),12 molecules that contain the Ar2CF2 or ArCF2OR moieties are considerably less stable

  

Source: Lectka, Thomas - Department of Chemistry, Johns Hopkins University

 

Collection: Chemistry

 
49 GTQ, Chemistry 212, Dr. Glaser, FS96 --1 --GTQ on Aldol Reactions. (40 points, reactivity, synthesis, disconnection)
 

Summary:  " between a ketone and a non-enolizable aldehyde is usually clean and leads to one product. This is so... because the carbonyl activity of the aldehyde far exceeds that of the ketone. To make sure that the ketone... does not react several times (at the same or at different -positions) one uses an excess of the ...

  

Source: Glaser, Rainer - Department of Chemistry, University of Missouri-Columbia

 

Collection: Chemistry

 
50 Small Molecule Ligands for Bulged RNA Secondary Structures
 

Summary:  ,c,d,f We therefore designed ketone 2 (Figure 1), which was suggested by computational modeling to have... to enhanced stability of the core scaffold. The synthesis of 2 commenced from the known ketone 3 (Scheme 1... acid cleanly effected its dehydration with concomitant cleavage of the ketal, affording ketone 5

  

Source: Hergenrother, Paul J. - Department of Chemistry, University of Illinois at Urbana-Champaign

 

Collection: Chemistry

 
51 [Reprintedfrom the,Journalof OrganicChemistry,39,400(1974).] CopyrightI974bytheAmericanChemicalSocietyandreprintedby permissionof thecopyrightowner.
 

Summary:  -bromopentane, methyl vinyl ketone, and nitrobenzene. The relative yields of prod- ucts observed... reactivities of the two organic groups in these complexes. Organic moieties that form stable, unreactive... of an organolithi- um compound derived fiom a difl'erent organic moiety: these solutions ma3' show a pronounced

  

Source: Prentiss, Mara - Department of Physics, Harvard University

 

Collection: Physics

 
52 Strategies for the Asymmetric Synthesis of Tertiary Alcohols Kimberly S. Petersen
 

Summary:  addition to ketones 1,2-metallate rearrangement of boronate complexes R1 R2 O R3 OTMS + aldol type... oxidation of C-O possible for kinetic resolution -No hydrogenation of carbonyl possible -Ketones are less... Catalyzed Enantioselective Aldol Reactions Ketones R1 O R2 + OTMS OMe OH O OMe R2 R1 1. Taniaphos (5 mol

  

Source: Stoltz, Brian M. - Division of Chemistry and Chemical Engineering, California Institute of Technology

 

Collection: Chemistry

 
53 TetrahedronLetters,Vo1.32,No.37,pp 48354838, 1991 Printed in Great Britain
 

Summary:  D-threoconfigurationandcanbeobtained from a stereoselective,TK-catalyzedtransfornration.We envisionedtrihydroxy ketone5 as the central 4835... .5 effected the smooth conversionof 6 to hydroxy ketone5 in 45Voyield (909i,of theoreticalyieid).6'7Without p... SMosher'sacidandfoundtheenantiomericexcessof T,andhencetheentiresequence,tobegreaterthan ...

  

Source: Prentiss, Mara - Department of Physics, Harvard University

 

Collection: Physics

 
54 Tetrahedron Letters, Vol. 37, No. 41, pp. 7335-7338, 1996 Copyright 1996 Elsevier Science Ltd
 

Summary:  of the ketone and ct-hydroxy moieties. MeC2C Benzene, 3 HO CH3 25 °C, 2tl ii L CH 3 iii Tanida, S.; Takizawa, M... to be a trivial alkylation of the C(3') hydroxyl. Much to our surprise, ketone 14 proved quite resistant... ,14 Having rapidly assembled a-methoxy ketone 15, we investigated its conversion to ...

  

Source: Stoltz, Brian M. - Division of Chemistry and Chemical Engineering, California Institute of Technology

 

Collection: Chemistry

 
55 Baeyer-Villiger monooxygenases, an emerging family of flavin-dependent
 

Summary:  novel BVMOs from sequenced genomes will be discussed. 1. INTRODUCTION The conversion of ketones... into esters or cyclic ketones into lactones was discovered more than a century ago by Adolf von Baeyer... and Victor Villiger (Baeyer and Villiger, 1899). In this reaction, the ketone is attacked by a nucleophilic

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
56 Summary & discussion 1. INTRODUCTION
 

Summary:  Baeyer and Victor Villiger described a method for the transformation of ketones into esters or cyclic... ketones into lactones by the use of peracids (Baeyer and Villiger, 1899). Since then, the Baeyer... to play a role in microbial degradation of aliphatic methyl ketones, alicyclic ketones, terpenes

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
57 Enantioselective Synthesis of Trifluoromethyl Substituted
 

Summary:  of Arylboronic Acids to Trifluoromethyl Ketones", in press. #12;136 Chapter 7 7.1 Introduction Due... alcohols would be the addition of carbon nucleophiles to trifluoromethyl ketones. The enantioselective... formation of quaternary carbons via the addition of carbon nucleophiles to ketones, however, still

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
58 Aldehydes and Ketones Unknown/Derivative 29 Carbonyl Unknowns
 

Summary:  Aldehydes and Ketones Unknown/Derivative 29 Carbonyl Unknowns Overview: You will receive a carbonyl... compound as an unknown. It can be either an aldehyde or a ketone, and may or may not contain an aromatic... for aldehydes or ketones. · Schiff's test: Positive for Aldehydes, not for Ketones · Tollens' ...

  

Source: Jasperse, Craig P. - Department of Chemistry, Minnesota State University Moorhead

 

Collection: Chemistry

 
59 RAPID COMMUNICATIONS IN MASS SPECTROMETRY Rapid Commun. Mass Spectrom. 2003; 17: 16771684
 

Summary:  benzophenone moiety. Analysis of peak profiles for the photo- labeled ions does not indicate the typical `peak... involving phenyl migration and ketone formation has formed an unexpected oxidized peptide, with molecular... consistent with the presence of a BP moiety were identified (marked by asterisks in Figs. 1(B) and 1(D

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
60 Discovery, Redesign and Applications of Baeyer-Villiger
 

Summary:  then 100 years ago by Adolf von Baeyer and Victor Villiger.[1] By this reaction, ketones are converted... of a tetrahedral intermediate by the nucleophilic attack of the peracid onto the ketone.[2] This intermediate... used in organic chemistry and will react with a ketone to form an ester. In fact, it is the ability

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology


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61 Tetrahedron Letters,Vo1.28,No.44,pp 5287-5290,1987 oo40-4039/87 $3.00 + .OO Printed in Great Britain Pergamon Journals Ltd.
 

Summary:  a requirement arose for the selective saturation of the acrylate moiety in l.* Review of the literature3... ;5288 The results of our study are summarized in Table 1. In each case the acrylate moiety was selectively saturated... in the presence of isolated olefins, enol ethers, and epoxides. Isolated ketones underwent partial ...

  

Source: Hudlicky, Tomas - Department of Chemistry, Brock University

 

Collection: Chemistry

 
62 Science in China Series B: Chemistry 2009 SCIENCE IN CHINA PRESS
 

Summary:  furan products with one more substituent when treated with additional nucleophilic reagents. -ketone... ()-catalyzed re- action of -allenic ketones to form polysubstituted furan products through intramolecular... treated with base. Besides, -ketone allenic sulfides can also cyclize to give furan derivatives under

  

Source: Wang, Jianbo - College of Chemistry, Peking University

 

Collection: Chemistry

 
63 Light-Driven Molecular Motors and Switches Controlling Rotary Motion and Supramolecular Helicity
 

Summary:  -Based Lower-Half 97 3.2.2 Substitution of the Naphthalene for a Substituted Phenyl Moiety 99 3.3 New Design... Synthesis of Ketone Precursors 125 4.2.2 Non-Racemizing Coupling Conditions 128 4.3 More Efficient... Enantioselective Synthesis of Upper-Half Ketones 131 4.3.1 Synthetic Strategy I: Starting from Enantiomerically

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
64 Enantioselective Total Synthesis of Bistramide A Michael T. Crimmins* and Amy C. DeBaillie
 

Summary:  -trimethylsilyloxy-1,3-pentadiene,11 in the presence of TMSOTf, installed the R, -unsaturated ketone moiety of pyran... two steps. The azide moiety was then installed via a Mitsunobu reaction14 with diphenylphos- phoryl... the hydroxy acid in 66% yield over two steps. The azide moiety was readily reduced to ...

  

Source: Crimmins, Michael T.- Department of Chemistry, University of North Carolina at Chapel Hill

 

Collection: Chemistry

 
65 Toward the Total Synthesis of Maoecrystal V: Establishment of
 

Summary:  -membered lactone, a tetrahydrofuran, a cyclohexenone, and a bicyclo[2.2.2]octane moiety. This ring system contains... and adjacent tertiary alcohol moiety that make this natural product such a challenging synthetic target. Our... . Treatment of ketone 6 with Nagata's reagent (Et2AlCN)7 not only resulted in the formation of the ...

  

Source: Trauner, Dirk - Department Chemie, Ludwig Maximilians Universität München

 

Collection: Chemistry

 
66 Summary and outlook Summary and outlook
 

Summary:  of a ketone to an ester, but also sulfoxidations and a number of other oxidation reactions. Except... on small cyclic ketones (cyclopentanone and cyclohexanone),[17-19] variants that are active with larger... cyclic ketones (e.g. cyclopentadecanone),[20,21] aromatic ketones (4-hydroxy- acetophenone),[22

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
67 A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells q
 

Summary:  upon the electrophilicity of the ketone. In addition, aromatic moieties appear to be unfavorable... results in a decrease in cell invasion. A series of compounds containing a trifluoromethyl ketone (TFK... ) moiety or the methyl analog (known to inhibit carboxylesterases) were investigated for their ability

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
68 Synthesis of New Carboxylesterase Inhibitors and Evaluation of Potency and Water Solubility
 

Summary:  ) and forming a stable analogue (34). The binding of an enzyme to the ketone moiety also results... of potent and selective inhibitors. Trifluoromethyl ketone (TFK)-containing compounds are the most potent... esterase inhibitors described to date. The inclusion of a thioether moiety to the carbonyl further

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
69 Organocatalytic Transfer Hydrogenation of Cyclic Enones Jamison B. Tuttle, Stephane G. Ouellet, and David W. C. MacMillan*
 

Summary:  organocatalytic transfer hydrogenation of R, - unsaturated ketones, an operationally trivial protocol that allows... that ketones are sterically and electronically deactivated toward iminium formation in comparison to aldehydic... ) Et, 82% ee). Furthermore, the relative size of the ester moieties at the 3,5-dihydropyridine site

  

Source: MacMillan, David W. C. - Department of Chemistry, Princeton University

 

Collection: Chemistry

 
70 Chem.Res. Toxicol. 1990,3, 325-332 325 Heterocyclic Derivatives of
 

Summary:  )trifluoropropanonescontaining a heterocyclic moiety was synthesized. The compounds were tested for in vitro inhibition of four hydrolytic... bond. These results provide indirect support that trifluoromethyl ketones are transition-state mimic... , and pyrimidyl moiety showed the highest inhibition of this enzyme. Differential ...

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
71 GTQ, Chemistry 212, Dr. Glaser, FS96 --1 --GTQ on Aldol Reactions. (40 points, reactivity, synthesis, disconnection)
 

Summary:  . Glaser, FS96 -- 2 -- (c) The "mixed aldol reaction" between a ketone and a non-enolizable aldehyde... exceeds that of the ketone. To make sure that the ketone does not react several times (at the same... or at different -positions) one uses an excess of the ketone. Draw the structures of the products formed ...

  

Source: Glaser, Rainer - Department of Chemistry, University of Missouri-Columbia

 

Collection: Chemistry

 
72 Using Peptidic Inhibitors to Systematically Probe the S1 Site of
 

Summary:  , Illinois 61801 hergenro@uiuc.edu Received June 1, 2005 ABSTRACT Fifteen ketone-containing peptides were... recognition sequence (DEVD) constant while chang- ing only the P1 position. In this design, a ketone replaces... such ketones to reversibly form thio-hemiacetals.11 A range of R groups can then project from the ...

  

Source: Hergenrother, Paul J. - Department of Chemistry, University of Illinois at Urbana-Champaign

 

Collection: Chemistry

 
73 Stereospecic synthesis of -C-glycosyl derivatives (``-C-glycosides'') of
 

Summary:  or 2-pyridyl sulfone derivatives reacted with ketones or aldehydes resulting in the instantaneous... of the SO2Ar when com- pared to the phenyl sulfone moiety [5]. This decreased energy facilitated a one... by the reports of SinayÈ [7] and Wong [8] on the samarium-mediated coupling of - alkoxy sulfones with ketones

  

Source: Linhardt, Robert J. - Center for Biotechnology and Interdisciplinary Studies & Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute

 

Collection: Biotechnology ; Chemistry

 
74 06502/CISM/jys Center for Industrial Sensors and Measurements
 

Summary:  in the molecular structures extend from the surface into nonaqueous solvent and act as good moieties in nonaqueous... ; the other type can act in the moieties extending into a nonaqueous solution. Steric stabilization... (CH3)2Si(OCH3)] 28 A.7 Styrene 28 #12;Table of contents 3 A.8 Methyl ethyl ketone 28 A.9 Alkyl poly

  

Source: Verweij, Henk - Department of Materials Science and Engineering, Ohio State University

 

Collection: Materials Science

 
75 An Electrochemical Approach to the Guanacastepenes
 

Summary:  that contain additional dihydrofuran or furanone moieties. Guanacastepene A has received considerable attention... versatility of the furan moiety allowed us to forge the guanacastepene skeleton in another way. Concomitantly... acid-catalyzed isomerization of the cyclopentenone to the achiral ,-unsaturated ketone. Cyclopentenone

  

Source: Trauner, Dirk - Department Chemie, Ludwig Maximilians Universität München

 

Collection: Chemistry

 
76 structural communications 842 doi:10.1107/S1744309111018604 Acta Cryst. (2011). F67, 842850
 

Summary:  identification and crystal structure validation of caspase-3 inhibitors without a P1 aspartic acid moiety... used warheads are halomethyl ketones and aldehydes. Coupled with the preferred tetrapeptide sequence... .1. Computational screening We used in silico screening to identify compounds containing halomethyl ketone

  

Source: Caflisch, Amedeo - Department of Biochemistry, Universität Zürich

 

Collection: Biology and Medicine

 
77 Bioorganic &Medicinal Chemistry Letters 8 (1998) 613-618 BIOORGANIC &
 

Summary:  the trifluoromethyl ketone of oleic acid, one of the most potent FAAH inhibitors described to date. This study... documenting the active site alkylation of proteases by a-halo ketones.`7 However, the kinetics of inhibition... slightly increased potency (3, Ki = 0.55 p&I). Replacement of the C-l bromine moiety with chlorine ...

  

Source: Cravatt, Benjamin - Department of Cell Biology, Scripps Research Institute

 

Collection: Biology and Medicine

 
78 October 2002 Organic Chemistry Cume
 

Summary:  hydrogenation of simple ketones was discovered in 1995. This method involves catalysts of the type [RuX2... salt? The cinchona alkaloids also contain a quinoline moiety. Draw the structure of quinoline. Do you

  

Source: Glaser, Rainer - Department of Chemistry, University of Missouri-Columbia

 

Collection: Chemistry

 
79 CHM 7200 Organic Structures and Mechanisms Fall Term 2006 Problem Set 3: This problem set is now available at (www.blackboard.wayne.edu). It will be due
 

Summary:  , 3254.) The illustrated substrates will undergo fragmentation to an olefinic ketone IF the appropriate... - (phenylsulfanyl)ethyl moiety, as indicated below. Using three-dimensional drawings, provide a rational mechanism

  

Source: Andreana, Peter R. - Department of Chemistry, Wayne State University

 

Collection: Chemistry

 
80 Molecular Cell, Vol. 6, 909919, October, 2000, Copyright 2000 by Cell Press Structural Determinants of Phosphoinositide
 

Summary:  in the electron densitythe ketone oxygen of quercetin, the hydroxyl oxygens of the phenyl moiety of myricetin... of Lys-833 and the ketone moiety. Removal of the phenyl ring decreases droxyphenyl)-3,5,7-trihydroxy-4H-1... decrease the IC50 (Matter et al., 1992). #12;Molecular Cell 916 Additionally, the ...

  

Source: Williams, Roger L. - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine


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81 Tetrahedron Letters,Vol.24,No.5,pp 427-430,1983 0040-4039/83/050427-04$03.00/0 Printed in Great Britain 01983 Pergamon Press Ltd.
 

Summary:  as precursors to this spiroketal moiety. Milbemycin B3 1- Our plan recognized a cascading cyclization... methyl ketone $ in 65% yield for the two steps.6 Kinetic deprotonation (LDA, 2 equivs, THF, HMPA, -78 'C... obtainedwith 60 to 70% recoveredmethyl ketone 4. None of the usual techniques,such as lower reaction

  

Source: Williams, David R. - Department of Chemistry, Indiana University

 

Collection: Chemistry

 
82 Synthesis of Taiwaniaquinoids via Nazarov Triflation Guangxin Liang, Yue Xu, Ian B. Seiple, and Dirk Trauner*
 

Summary:  for the construction of the central indanone or indene moieties of these natural products. In the course of our studies... afforded aryl vinyl carbinol 14. This sensitive alcohol was oxidized immediately to yield aryl vinyl ketone... ) should afford the corresponding enol triflate.5 Indeed, heating of aryl vinyl ketone 15 with ...

  

Source: Trauner, Dirk - Department Chemie, Ludwig Maximilians Universität München

 

Collection: Chemistry

 
83 Light-Driven Molecular Motors and Switches Controlling Rotary Motion and Supramolecular Helicity
 

Summary:  -Based Lower-Half 97 3.2.2 Substitution of the Naphthalene for a Substituted Phenyl Moiety 99 3.3 New Design... Synthesis of Ketone Precursors 125 4.2.2 Non-Racemizing Coupling Conditions 128 4.3 More Efficient... Enantioselective Synthesis of Upper-Half Ketones 131 4.3.1 Synthetic Strategy I: Starting from Enantiomerically

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
84 Parkinson's disease is a serious neurological disorder of the central nervous system that usually becomes apparent after the age of 55. It concerns the increased deterioration of neurons
 

Summary:  on the bioactivation mechanism. A number of analogs of PD148903 with the ketone moiety in a different position were... to the ketone after which oxidation and keto- enol tautomerization lead to the corresponding catecholamine... synthesized in order to obtain a series of compounds in which the ketone was ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
85 Phosphoramidites as ligands for copper in catalytic asymmetric C-C bond forming reactions
 

Summary:  ketones, electrophiles were used in a tandem approach for -functionalization of the ketones... stereodifferentiation". Most of chiral P,N ligands employed bear two chiral moieties resulting in a matched... -threo hydroxy ketones in up to 76% yield and with ees up to 97% (Scheme 5.3). The means that three ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
86 Journal of Membrane Science 173 (2000) 1734 Proton Conducting Composite Membranes from Polyether Ether Ketone and
 

Summary:  Ether Ketone and Heteropolyacids for Fuel Cell Applications S.M.J. Zaidi a, S.D. Mikhailenkoa, G... ketone with embedded powdered heteropolycompounds was prepared and their electrochemical and thermal... -exchange membrane; Polyether ether ketone (PEEK); Heteropolyacids #12;

  

Source: Zaidi, S. M. Javaid - Department of Chemical Engineering, King Fahd University of Petroleum and Minerals

 

Collection: Engineering ; Materials Science

 
87 Perceptual and Neural Olfactory Similarity in Honeybees
 

Summary:  (primary and secondary alcohols, aldehydes and ketones) and in their carbon-chain length (from six to nine... presented could be learned, although acquisition was lower for short-chain ketones; (ii) generalisation... , respectively), aldehydes, and ketones. They possessed therefore three functional groups (alcohol, aldehyde

  

Source: Menzel, Randolf - Institut für Biologie - Institut für Biologie, Freie Universität Berlin

 

Collection: Biology and Medicine

 
88 Baeyer-Villiger Monooxygenases as Biocatalysts in the Synthesis of
 

Summary:  Thermobifida fusca are Baeyer-Villiger monooxygenases that oxidize aromatic organic compounds such as ketones... , revealing its reactivity with a large range of sulfides and ketones. In addition, we studied... the nucleophilic oxygenation of ketones and boron as well as the electrophilic oxygenation of various heteroatoms

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
89 Structural Studies of a Potent Insect Maturation Inhibitor Bound to the Juvenile Hormone Esterase of Manduca sexta,
 

Summary:  ketone (TFK) moiety and have a sulfur atom to the ketone. In this study, sulfur-aromatic interactions... or ester moiety. The relative importance of these two pathways, both catalyzed by R/ -hydrolase enzymes (4... -18). These compounds include the trifluoromethyl ketone (TFK) inhibitors ...

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
90 Artificial Phosphate Transferases and Hydrogen Tranferases Based on Biotin-
 

Summary:  transfer, transfer hydrogenation, ketone reduction, imine reduction, cerium. #12;4 Table of contents... FOR THE ENANTIOSELECTIVE REDUCTION OF ARYL KETONES AND CYCLIC IMINES 94 1. ABSTRACT 94 2. INTRODUCTION 95 2.1 TRANSFER... HYDROGENATION 95 2.2. IMINE REDUCTION 103 3. KETONE REDUCTION: RESULTS AND DISCUSSION 111 3.1 EXTRACTION

  

Source: Amrhein, Valentin - Zoologisches Institut, Universität Basel

 

Collection: Environmental Sciences and Ecology

 
91 Strategies for the Total Synthesis of C2-C11 Cyclized Cembranoids J. Michael Ellis and Michael T. Crimmins*
 

Summary:  of the terminal alkene with subsequent vinylation of the resultant ketone provided tertiary alcohol 29 in 75... the six- and nine- membered rings. Diastereoselective addition of methyllithium to the ketone 31... conjugate addition of the Gilman reagent derived from isopropylmagnesium chlo- ride provided ketone 33

  

Source: Crimmins, Michael T.- Department of Chemistry, University of North Carolina at Chapel Hill

 

Collection: Chemistry

 
92 TETRAHEDRON Tetrahedron Letters 44 (2003) 587589Pergamon
 

Summary:  cyclopentenone derivatives starting from cyclic ketones has been developed. © 2002 Elsevier Science Ltd. All... C H bond insertion by Rh(II) carbene (Scheme 1). Thus, the nucleophilic addition to cyclic ketones 1... a­d by Ti(IV) enolates 2a­b derived from an a-diazo-b-keto ester or a ketone is expected to give

  

Source: Wang, Jianbo - College of Chemistry, Peking University

 

Collection: Chemistry

 
93 Asymmetric transfer hydrogenations
 

Summary:  examples of the asymmetric reduction of olefinic double bonds in ,-unsaturated ketones with molecular... to acyclic ,- unsaturated ketones and esters which afforded very high enantioselectivities whereas for cyclic... ketones and lactones reduction was not observed. O nC6H13 2.0 mol % CuH 1.0 mol % L4 PMHS, -78o C PhMe O n

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
94 J. Am. Chem. Soc. 1984,106,687-694 687 f0.2 e A-3. For 1.4B, the final discrepancy indexesare R = 0.086 and
 

Summary:  bicyclic ketones give AJ values of approximately 20 Hz, indicating that in all cases bisected... cyclopropylcarbinylgeometries prevail. Conformations of these and related cations and of the bicyclic ketones are discussed... the cyclopropylcarbinyl moiety was not in the favored bisected arrangement, but one intermediate between

  

Source: Smith, Bradley D. - Department of Chemistry and Biochemistry, University of Notre Dame

 

Collection: Chemistry

 
95 2134 J. Org. Chem. 1988,53, 2134-2136 between the Sm3+chelate and the carboxylate would ac-
 

Summary:  documented,sbJ1 and intramolecular addition of alkyl radicals to unactivated ketones and aldehydes is now... ,8117, 8119. (3) Sodium borohydride reduction of the C5ketone of 2 is known to stereoselectively yield... , M. J. Antibiot. 1983,36,991. Furthermore, we had recognized that the presence of the C5ketone

  

Source: Williams, David R. - Department of Chemistry, Indiana University

 

Collection: Chemistry

 
96 Communications Reactivity of a Well-Characterized Titananorbornadiene
 

Summary:  with Ketones and Aldehydes Oleg V. Ozerov, Sean Parkin, Carolyn P. Brock, and Folami T. Ladipo* Department... : The reaction between the titananorborna- diene complex [(DMSC)Ti(6-1,2,4-(Me3Si)3C6H3)] (2) and ketones... or aldehydes proceeds by insertion of a ketone or aldehyde molecule into a Ti-C bond of 2, yielding 2

  

Source: Parkin, Sean - X-Ray Laboratory & Department of Chemistry, University of Kentucky

 

Collection: Chemistry

 
97 A Structure-Based Design Approach to the Development of Novel, Reversible AChE Inhibitors
 

Summary:  -c). Close analogues that lack the full trifluoromethyl ketone moiety (18), or have been reduced... the two moieties (respectively 5-6 and 4-5 sp3 atoms). Seven compounds matching these criteria were... with the corresponding acceptor-donor distances are in green. Figure 3. Binding mode of trifluoromethyl ...

  

Source: Sussman, Joel L. - Department of Structural Biology, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
98 Analysis of Mammalian Carboxylesterase Inhibition by Trifluoromethylketone-Containing Compounds
 

Summary:  trifluoromethyl group in the position with respect to the ketone moiety (Fig. 1). The trifluoroacyl chemotype... inhibitors identified to date are a group of compounds collectively known as trifluoro- methyl ketones (TFKs... .021683. ABBREVIATIONS: CE, carboxylesterase; CPT-11, irinotecan; TFK, trifluoromethyl ...

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
99 266 Langmuir 1986,2, 266-281 acetylene dose due to the high supply of hydrogen.
 

Summary:  of coupling chemistry may also be involved,reflecting reaction of the ketone moieties present in PE-C02Hwith... have attached the fluorophoricdanayl[5-(dimethylamino)naphthalene-l-sulfonyl]moiety to carboxylic acid... and acidity of the local environment. The functionalization procedure used introduced -6 X 1014dansyl ...

  

Source: Prentiss, Mara - Department of Physics, Harvard University

 

Collection: Physics

 
100 Synthesis of the Bis-tetrahydropyran Core of Amphidinol 3
 

Summary:  moieties (C1-C30).3 In 2008, Murata published a revised structure, in which the absolute configuration at C... of the C31-C39 and C44-C52 tetrahydropyran moieties to access the core bis-tetrahydropyran unit. A Horner... utilizing methyl copper and di- isobutylaluminum hydride21 to provide ketone 23. Subse- quent transformation

  

Source: Crimmins, Michael T.- Department of Chemistry, University of North Carolina at Chapel Hill

 

Collection: Chemistry


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