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Sample search results for: aav-expressed persistent antigen

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1 Gene conversion and diversification of antigen repertoires Proposer: Jay Taylor
 

Summary:  develop against these antigen types, the infection can persist if small numbers of parasites randomly... Gene conversion and diversification of antigen repertoires Proposer: Jay Taylor Parasites... responses mounted by their hosts. One strategy, called antigenic variation, relies on the parasite surface

  

Source: Goldschmidt, Christina - Department of Statistics, University of Warwick

 

Collection: Mathematics

 
2 libtissue -implementing innate immunity Jamie Twycross, Uwe Aickelin
 

Summary:  is that of antigen persistence. In the biological system indi- vidual antigen do not persist indefinitely... and control problems. AIS algorithms are implemented as multi- agent systems of cells, antigen and signals... . The key elements of the system are cells, signals and ...

  

Source: Twycross, Jamie - School of Computer Science, University of Nottingham

 

Collection: Computer Technologies and Information Sciences

 
3 Immunology and Cell Biology (2004) 82, 5561 Special Feature
 

Summary:  Immunology and Cell Biology (2004) 82, 55­61 Special Feature Modelling the impact of antigen... that the mode of introduction and the dose of antigen can affect these qualitative aspects of the response... we use to study the impact of antigen dose, antigen kinetics and repeated antigen ...

  

Source: New Mexico, University of - Santa Fe Institute & Department of Computer Science, Computer Immune Systems Group

 

Collection: Biology and Medicine ; Computer Technologies and Information Sciences

 
4 Proc. Natl. Acad. Sci. USA Vol. 96, pp. 99739975, August 1999
 

Summary:  a partial hepatectomy before retroviral vector administration to achieve a partial but persistent correction... may relate to current concepts of tolerance and antigen presentation (33, 34). Induction of inhibitors... with the antigen during therapy with clotting factor, promote the induction of a neutralizing antibody response

  

Source: Kay, Mark A. - Department of Genetics, Stanford University

 

Collection: Biology and Medicine

 
5 Comments and Study Questions for Campbell Chapter 43 (Immune System) General Biology 2
 

Summary:  not confuse with cytokines) antigen, epitope, B and T lymphocytes (B&T cells), antigen receptors... , immunoglobulins (secreted antibodies), major histocompatibility complex (MHC), antigen presentation, class 1 MHC... in a bit more detail in class. #12;2 END MATERIAL FOR EXAM #3 7. What are antigens and ...

  

Source: Prestwich, Ken - Biology Department, College of the Holy Cross

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
6 Available online at www.sciencedirect.com B cell acquisition of antigen in vivo
 

Summary:  and colleagues support a role for antigen persistence in maintenance of B cell memory [19,20]. More recent... is independent of persisting immunizing antigen. Nature 2000, 407:636-641. 24. Hannum LG, Haberman AM, Anderson... Available online at www.sciencedirect.com B cell acquisition of ...

  

Source: Carroll, Michael C. - Immune Disease Institute, Harvard University

 

Collection: Biology and Medicine

 
7 Immunological Memory is Associative Derek J. Smith
 

Summary:  persists. (d) A second exposure to the same antigen, or here a related antigen, restimulates the memory... of the humoral immune response. persisting antigen and the role of follicular antigen­binding dendritic cells... , Original Antigenic Sin, ...

  

Source: Somayaji, Anil - School of Computer Science, Carleton University

 

Collection: Computer Technologies and Information Sciences

 
8 INFECTION AND IMMUNITY, Aug. 2009, p. 32493257 Vol. 77, No. 8 0019-9567/09/$08.00 0 doi:10.1128/IAI.01448-08
 

Summary:  for Horizontal Gene Transfer of Two Antigenically Distinct O Antigens in Bordetella bronchiseptica Anne M... immunity is a major driving force of antigenic diversity, resulting in pathogens that can evade immunity... , express two antigenically distinct O-antigen serotypes (O1 and O2, ...

  

Source: Andrews, Anne M. - Huck Institutes of the Life Sciences, Pennsylvania State University

 

Collection: Biology and Medicine

 
9 Understanding the dynamics of rapidly evolving pathogens through modeling the tempo of antigenic change: Influenza as a case study
 

Summary:  between 0.1% and 6.2%, with a mean of 3.1%. (d) Duration of antigenic cluster persistence, in years... of antigenic cluster persistence, in years, computed from the simulations. Black curve shows the Weibull... ) partial, and immunity to a cluster may wane due to slight antigenic ...

  

Source: Pascual, Mercedes - Department of Ecology and Evolutionary Biology, University of Michigan

 

Collection: Biology and Medicine

 
10 INTEGRATED INNATE AND ADAPTIVE ARTIFICIAL IMMUNE SYSTEMS APPLIED TO
 

Summary:  antigen and corresponding cell response rates for the normal2 dataset... . Structural features of the problem are represented as antigen. Behavioural features are represented... functions of agents include antigen capture, pro- cessing, presentation and recognition, and signal

  

Source: Aickelin, Uwe - School of Computer Science, University of Nottingham

 

Collection: Computer Technologies and Information Sciences

 
11 INTEGRATED INNATE AND ADAPTIVE ARTIFICIAL IMMUNE SYSTEMS APPLIED TO
 

Summary:  antigen and corresponding cell response rates for the normal2 dataset... . Structural features of the problem are represented as antigen. Behavioural features are represented... functions of agents include antigen capture, pro- cessing, presentation and recognition, and signal

  

Source: Twycross, Jamie - School of Computer Science, University of Nottingham

 

Collection: Computer Technologies and Information Sciences

 
12 Antigenic Drift of Viruses Within a Host: A Finite Site Model with Demographic Stochasticity
 

Summary:  , thereby enabling them to persist for a prolonged period by shifting the dominant antigen types... the evolutionary process of antigen variants in a host is completely deter- mined by Eq. 1. The persistent time... therefore de- notes the persistent time of an ...

  

Source: Sasaki, Akira - Department of Biology, Kyushu University

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
13 0014-2980/00/0909-2704$17.50+.50/0 WILEY-VCH Verlag GmbH, D-69451 Weinheim, 2000 CD8 memory, immunodominance, and antigenic
 

Summary:  -span of the CTLp in the absence of antigen is short, the virus can establish a persistent infection. This can... and enables the virus to settle at a stable equilibrium. In contrast, with antigen- independent persistence... to an extremely low equilibrium abundance). Thus, antigen- ...

  

Source: Nowak, Martin A. - Department of Organismic and Evolutionary Biology, Harvard University

 

Collection: Environmental Sciences and Ecology

 
14 Reprinted from D. Scott Linthicum Nadir R. Farid
 

Summary:  with S-antigens. This also means that the persistent titer to a foreign antigen must be produced... to consist of a set of antigen specific lymphocytes that are selected in ontogeny to avoid reactivity... with self, leaving only reactivity with foreign antigens (l,2). In this theory, ...

  

Source: Cleveland, William Louis - Department of Medicine, Columbia University

 

Collection: Biology and Medicine

 
15 Immune System 1 Running Head: IMMUNE SYSTEM
 

Summary:  , it must be able to distinguish self from non-self substances called antigens (meaning "antibody generators... "). To efficiently eliminate antigens, the immune system must respond as quickly and as strongly as possible to kill... to antigen specific T and B lymphocytes, and (2) myeloid progenitors are the precursors for the ...

  

Source: Meagher, Mary - Department of Psychology, Texas A&M University

 

Collection: Biology and Medicine

 
16 PERSPECTIVE ARTICLE Why do adaptive immune responses cross-react?
 

Summary:  ). If cross-reactivity persists at million-fold dilutions (and it can), then the antigenic distance is small... of the immune system may also be important. For example, the persistence of cross-reactivity once antigenic... ability to recog- nize and bind diverse parasite antigens. As part ...

  

Source: Graham, Andrea L. - School of Biological Sciences, University of Edinburgh

 

Collection: Biology and Medicine

 
17 Pathogen Induced Tolerance Sean P. Stromberg
 

Summary:  , such a virus with a long latent phase or a chronic bacterial infection. The antigens from the persistent... . This model predicts "Original Antigenic Sin", but shows that average effector affinity is not an accurate mea... " (PIT), where antigen from the primary infection takes part in the immune system ...

  

Source: Carlson, Jean - Department of Physics, University of California at Santa Barbara

 

Collection: Physics

 
18 2001 Macmillan Magazines Ltd 60 | JANUARY 2002 | VOLUME 2 www.nature.com/reviews/immunol
 

Summary:  is a very important one,and that antigen persistence might be a crucial asset for any vaccine. Antigen... persistence and homeostasis The idea of long-lived antigen-independent memory cells does not fit with certain... .FDC-bound immune complexes are not the only examples of ...

  

Source: 

 

Collection: Biology and Medicine

 
19 Proc. Natl. Acad. Sci. USA Vol. 95, pp. 1492614931, December 1998
 

Summary:  ) ABSTRACT There has been much debate on the contri- bution of processes such as the persistence of antigens... of antigen-specific immune cells might require restimulation, either by persistent antigen or by repeated... decline in the popu- lation of these cells (5­7). Although ...

  

Source: Pilyugin, Sergei S. - Department of Mathematics, University of Florida

 

Collection: Mathematics

 
20 0022-1767/85/1345-3286$02.00/0 Copyright0 1985by The American Association of Immunologists
 

Summary:  - entiation, its expression persists or is enhanced during lymphoid differentiation. Five antigens, MAC-1, HSA... THEJOURNALOF hblUNOLoCY Vof. 134. No.5. May 1985 Prlnted fn U.S.A. IDENTIFICATIONOFCELL SURFACE ANTIGENS... antigens foundon murine bone marrowcells were examinedto define their patternof ...

  

Source: Springer, Timothy A. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine


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21 Behavioral/Systems/Cognitive Cdk5 Modulates Cocaine Reward, Motivation, and Striatal
 

Summary:  targeted delivery of recombinant adeno-associated virus (rAAV) expressing Cre recombinase to the NAc... with Avertin (240 mg/kg). Delivery of rAAV expressing Cre produced focal, conditional knock-out of Cdk5... specifically in neurons of the NAc, we delivered rAAV ...

  

Source: Yan, Zhen - Department of Physiology and Biophysics, State University of New York at Buffalo

 

Collection: Biology and Medicine

 
22 COIMMU-520; NO OF PAGES 10 Single-cell dynamics of T-cell priming
 

Summary:  . Immunol Rev 2006, 211:81-92. 7. Obst R, van Santen HM, Mathis D, Benoist C: Antigen persistence... of a T cell to find antigen-bearing DCs; the parameters that define the dose and quality of the antigenic... signal; and the mechanisms used by the T cell to interpret a given antigenic ...

  

Source: von Andrian, Ulrich H. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
23 Variable efficacy of repeated annual influenza vaccination Derek J. Smith, y Stephanie Forrest, y David H. Ackley, and Alan S. Perelson. zy
 

Summary:  antigenicity (observed vaccine efficacy in first­time vaccinees was only 21%) and antibody persistence was less... Keywords: influenza, vaccination, original antigenic sin, vaccine efficacy, repeated vaccination. 1 #12... , the antigenic distance hypothesis, and test it by analyzing seven influenza outbreaks ...

  

Source: New Mexico, University of - Santa Fe Institute & Department of Computer Science, Computer Immune Systems Group

 

Collection: Biology and Medicine ; Computer Technologies and Information Sciences

 
24 64 NATURE MEDICINE VOLUME 5 NUMBER 1 JANUARY 1999 Hemophilia is an X-linked recessive bleeding disorder that
 

Summary:  indicates that the AAV-expressed cFIX is immunologically indistinguishable from the normal c... resulted in the long-term persistence of factor IX (indicating permanence), the level of gene expression... infusion, the whole-blood clotting time (WBCT), serum cFIX antigen, plasma biofunctional FIX pro- tein (Fig

  

Source: Kay, Mark A. - Department of Genetics, Stanford University

 

Collection: Biology and Medicine

 
25 Anergy and Exhaustion Are Independent Mechanisms of Peripheral T Cell Tolerance
 

Summary:  to monitor antigen persistence and characterize antigen-specificT cells in terms of their frequency... of antigen, virgin TG cells persisted but did not expand. Transient exposure to antigen resulted in cell... expansion, followed by the ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
26 Grant Writing Project Summary (Abstract)
 

Summary:  and antigen-specific CD4+ T cells in the lungs are defective, and that this contributes to persistence... and antigen-specific CD4+ T cells in the lungs are defective, and that this contributes to persistence... and antigen-specific CD4+ T cells in the lungs are defective, and that this ...

  

Source: Wang, Da-Neng - Skirball Institute of Biomolecular Medicine & Department of Cell Biology, New York University

 

Collection: Biology and Medicine

 
27 J. theor. Biol. (2000) 203, 000}000 doi:10.1006/jtbi.2000.2001, available online at http://www.idealibrary.com on
 

Summary:  responds to a persistent antigenic stimulation. This situation simulates immune responses against various... (Received on 17 December 1998, Accepted in revised form on 18 January 2000) A dynamic antigen response... -space modelling by introducing the evolution of speci"city of idiotypes. When the amount of external ...

  

Source: Ikegami, Takashi - Department of General Systems Studies, University of Tokyo Graduate School of Arts and Sciences

 

Collection: Computer Technologies and Information Sciences

 
28 Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host
 

Summary:  infusion of a recombinant adeno-associated viral vector (rAAV) expressing canine Factor IX (F.IX) resulted... antigens of the AAV capsid caused both the decline in F.IX and the transient transaminitis. We conclude... , T cell­mediated immunity to AAV capsid antigens causes destruction of AAV-2­transduced ...

  

Source: Kay, Mark A. - Department of Genetics, Stanford University

 

Collection: Biology and Medicine

 
29 Mathematical Medicine and Biology (2006) 23, 255277 doi:10.1093/imammb/dql012
 

Summary:  cell receptors with improved binding characteristics for the antigen. The mechanism underlying B cell... antigen--even in the presence of competing secreted antibodies. Within the tested mechanisms, only clonal... centre characteristics and tolerating large variations in the initial antigen density. Keywords: germinal

  

Source: Maini, Philip K. - Centre for Mathematical Biology & Mathematical Institute, University of Oxford

 

Collection: Mathematics ; Biology and Medicine

 
30 Am J Respir Crit Care Med Vol 164. pp 9951001, 2001 Internet address: www.atsjournals.org
 

Summary:  sensitization to antigens may occur prenatally. We hy- pothesized that high prenatal exposure to indoor antigens... Manhattan were re- cruited and antigen was measured from home dust. After delivery, newborn cord... - sponse to antigen. Cockroach, mouse, but not dust mite antigens, were ...

  

Source: Columbia University, Department of Environmental Health Sciences, Columbia Center for Children’s Environmental Health

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
31 Antinuclear Antibodies as Potential Markers of Lung Cancer1 Felix Fernandez-Madrid,2
 

Summary:  of ANAs in lung cancer. We have previously reported that autoantibodies to collagen antigens resembling... that autoimmunity is often a prominent feature of lung cancer and that molecular characterization of these antigens... -specific antigens has been largely long and fruitless (1­3). However, T-cell ...

  

Source: VandeVord, Pamela - Department of Biomedical Engineering, Wayne State University

 

Collection: Engineering ; Biology and Medicine

 
32 Derek J. Smith Department of Computer Science
 

Summary:  population persists. (d) A second exposure to the same antigen, or here a related antigen, restimulates... , of the interference depended on the antigenic differences between the vaccine strains and epidemic strains used... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 3.2 Shape Space ...

  

Source: New Mexico, University of - Santa Fe Institute & Department of Computer Science, Computer Immune Systems Group

 

Collection: Biology and Medicine ; Computer Technologies and Information Sciences

 
33 Adenovirus Transduction is Required for the Correction of Diabetes Using Pdx-1 or
 

Summary:  -STZ administration, where both blood glucose levels were 4300 mg/dl after a 6 h fast. The recombinant AAVs expressing... . Response of diabetic mice to AAVs expressing pan- creatic transcription factors Weekly fasting blood... ) serotype 8, a vector that has been shown to result in non-toxic, ...

  

Source: Kay, Mark A. - Department of Genetics, Stanford University

 

Collection: Biology and Medicine

 
34 Derek J. Smith Department of Computer Science
 

Summary:  is cleared a memory population persists. (d) A second exposure to the same antigen, or here a related antigen... , of the interference depended on the antigenic differences between the vaccine strains and epidemic strains used... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 3.2 Shape ...

  

Source: New Mexico, University of - Santa Fe Institute & Department of Computer Science, Computer Immune Systems Group

 

Collection: Biology and Medicine ; Computer Technologies and Information Sciences

 
35 Variable efficacy of repeated annual influenza vaccination Derek J. Smith,
 

Summary:  , vaccination, original antigenic sin, vaccine efficacy, repeated vaccination. 1 #12;ABSTRACT Conclusions have... vaccination provided continual protection. We propose a novel explanation, the antigenic distance hypothesis... . The hypothesis is that variation in repeat vaccine efficacy is due to differences in antigenic distances ...

  

Source: New Mexico, University of - Santa Fe Institute & Department of Computer Science, Computer Immune Systems Group

 

Collection: Biology and Medicine ; Computer Technologies and Information Sciences

 
36 Immune responses against multiple epitopes: a theory for immunodominance and antigenic variation
 

Summary:  -reactive, epitopes. Antigenic oscillation in persistent virus infections The model can generate very complicated time... , Schnorr KL (1986) Rapid emergence of novel antigenic and genetic variants of EIAV during persistent... Immune responses against multiple epitopes: a theory for immunodominance and ...

  

Source: Nowak, Martin A. - Department of Organismic and Evolutionary Biology, Harvard University

 

Collection: Environmental Sciences and Ecology

 
37 J. theor. Biol. (1997) 186, 117129 00225193/97/090117 + 13 $25.00/0/jt960319 7 1997 Academic Press Limited
 

Summary:  (immune memory) requires the density of persistent antigen to be less than a defined threshold value... . If the amount of persistent antigen (or parasite) is greater than this threshold value then immune memory... of the immune response to persistent antigen (memory) ...

  

Source: Pilyugin, Sergei S. - Department of Mathematics, University of Florida

 

Collection: Mathematics

 
38 J. theor. Biol. (2003) 221, 585598 doi:10.1006/jtbi.2003.3208, available online at http://www.idealibrary.com on
 

Summary:  in modeling persistent infections. 7. Consider the how antigen-independent pro- liferation alter the dynamics... ­203. Wodarz, D., May, R. M., Nowak, M. A. (2000). The role of antigen-independent persistence of memory... ://www.idealibrary.com on Models of CD8+ Responses: 1. What is the ...

  

Source: Pilyugin, Sergei S. - Department of Mathematics, University of Florida

 

Collection: Mathematics

 
39 Research article 3106 TheJournalofClinicalInvestigation http://www.jci.org Volume 120 Number 9 September 2010
 

Summary:  or with imperfect or perfect targets for hepatic miR-122, plus AAV expressing Ago-2 (or a CMV control). The drop... /Xpo-5 AAV expression vectors (or none as control). (E) In vivo hAAT knockdown in hAAT-transgenic mice... , and persistence in the adult mouse liver Dirk Grimm,1,2 Lora ...

  

Source: Kay, Mark A. - Department of Genetics, Stanford University

 

Collection: Biology and Medicine

 
40 The Lymph Node B Cell Immune Response: Dynamic
 

Summary:  -based model helps researchers to study the ways the human body responds to the antigens that stimulate immune... lymphocytes respond to antigens to generate, among other cell types, plasma cells that secrete specific... antibodies and memory lymphocytes for enhanced future responses to the antigen. To achieve these ends

  

Source: Harel, David - Department of Computer Science and Applied Mathematics, Weizmann Institute of Science

 

Collection: Computer Technologies and Information Sciences


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41 [Frontiers in Bioscience 8, e315-322, May 1,2003] THE SIGNIFICANCE OF AUTOIMMUNITY IN THE PATHOGENESIS OF CHAGAS HEART DISEASE
 

Summary:  infection, particularly immunity to parasite antigens that may persist in the infected animal. While... responses to persistent parasites or parasite antigens; (ii) autoimmunity induced by T. cruzi; (iii... antigens and DNA have been shown to persist in the tissues ...

  

Source: Engman, David M. - Departments of Pathology & Microbiology-Immunology, Northwestern University

 

Collection: Biology and Medicine

 
42 INFECTION AND IMMUNITY, June 2008, p. 26032611 Vol. 76, No. 6 0019-9567/08/$08.00 0 doi:10.1128/IAI.01718-07
 

Summary:  to require a greater quantity and longer persistence of cognate antigen than the stimulation of CD8 T cells... immunized with a larger dose of LFn fusion protein, or if the antigen were made to persist by giving several... 8 T Cells Respond to Antigens Fused to Anthrax Lethal Toxin ...

  

Source: Starnbach, Michael - Department of Microbiology and Molecular Genetics, Harvard University

 

Collection: Biology and Medicine

 
43 Artificial Immune Systems 209 Artificial Immune Systems
 

Summary:  , fungi and other parasites. On the surface of these agents are antigens; it is these antigens... that is capable of generating such a response from the lymphocytes is called an antigen or immuno- gen... foreign. Immune responses are normally directed against the antigen that provoked them and are said

  

Source: Timmis, Jon - Departments of Computer Science & Electronics, University of York (UK)

 

Collection: Computer Technologies and Information Sciences

 
44 Visualization of Antigen-Specific T Cell Activation in Vivo in Response to Intracerebral Administration of a Xenopeptide
 

Summary:  Visualization of Antigen-Specific T Cell Activation in Vivo in Response to Intracerebral... , we need to first understand how the immune system responds to CNS antigens leading to graft rejection... . In order to monitor immune system responses to CNS antigens an adop- tive transfer system was used

  

Source: Low, Walter C. - Department of Integrative Biology and Physiology, University of Minnesota

 

Collection: Biology and Medicine

 
45 2003 Prunella Publishers37 Montana 2003
 

Summary:  ). The marmot sera were tested for woodchuck hepatitis surface antigen, antibody to woodchuck hepatitis virus... core antigen, and virus-specific DNA polymerase at the Laboratory of Infectious Diseases... and structural relatedness between the respective surface antigen formsforWHVandGSHV(Summers1981).Furthermore

  

Source: Blumstein, Daniel T. - Department of Ecology and Evolutionary Biology, University of California at Los Angeles

 

Collection: Environmental Sciences and Ecology

 
46 A Multi-layered Immune Inspired Machine Learning Algorithm
 

Summary:  response of these B-cells to antigenic stimulation. AINE was applied to the Fisher Iris data set and was re... viewpoint, it would not be a preferential out- come: it is clearly more desirable if all patterns persist... , these are known as antigens. As part of the adaptive immune system a B-cell is capable of recognizing free

  

Source: Timmis, Jon - Departments of Computer Science & Electronics, University of York (UK)

 

Collection: Computer Technologies and Information Sciences

 
47 Virus-specific CD8 T cells during chronic infection often exceed in numbers virus-replicating infected cells. Why then do
 

Summary:  chronic viruses survive Lieberman, Manjunath and Shankar 479 Figure 1 (a) Cleared antigen (b) Persistent... development is altered in the setting of persistent antigen (Ag). (a) During an acute infection... ) In the setting of persistent antigen, less IL-2 is ...

  

Source: Lieberman, Judy - Immune Disease Institute, Harvard University

 

Collection: Biology and Medicine

 
48 Proc. Natl. Acad. Sci. USA Vol. 93, pp. 985989, February 1996
 

Summary:  gener- ation of antigenic variants can enhance the likelihood of parasite persistence in the face... Proc. Natl. Acad. Sci. USA Vol. 93, pp. 985­989, February 1996 Immunology Antigenic variation... , University of Oxford, Oxford, United Kingdom, October 11, 1995 ABSTRACT Many parasites exhibit antigenic

  

Source: Nowak, Martin A. - Department of Organismic and Evolutionary Biology, Harvard University

 

Collection: Environmental Sciences and Ecology

 
49 Replication-defective viruses as vaccines and vaccine vectors Tim Dudek a,b
 

Summary:  with adenovirus. rAAV expressing SIV genes has recently been shown to elicit an immune response that significantly... but expressing viral antigens inside infected cells so that MHC class I and class II presentation can occur... for the expression of heterologous antigens. The potential advantages and ...

  

Source: Knipe, David M. - Department of Microbiology and Molecular Genetics, Harvard University

 

Collection: Biology and Medicine

 
50 MELANOMA (KIM MARGOLIN, SECTION EDITOR) Immunobiology of Merkel Cell Carcinoma: Implications
 

Summary:  except in the setting of dying or diseased tissue (such as a tumor that persistently expresses T-antigens... persistent expression of immunogenic viral proteins, however, MCC tumors are able to evade the immune system... . Tumor infiltrating lymphocytes . TILs . Viral oncoproteins . T-antigen . Immune ...

  

Source: Nghiem, Paul - Cutaneous Biology Research Center, Massachusetts General Hospital

 

Collection: Biology and Medicine

 
51 BioMed Central Page 1 of 13
 

Summary:  , antigenic mutability facilitates long-term persist- ence, whereas Keeling did not discuss antigenic... AccessResearch article Barriers to antigenic escape by pathogens: trade-off between reproductive rate... and antigenic mutability Steven A Frank* and Robin M Bush Address: Department ...

  

Source: Frank, Steven A. - Department of Ecology and Evolutionary Biology, School of Biological Sciences, University of California, Irvine

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
52 Current Drug Delivery, 2011, 8, 000-000 1 1567-2018/11 $58.00+.00 2011 Bentham Science Publishers Ltd.
 

Summary:  Ltd. The Release and Induced Immune Responses of a Plant-Made and Deliv- ered Antigen in the Mouse Gut... , Victoria 3800, Australia Abstract: This study investigated the site of release of a model vaccine antigen... technique that enabled detection of antigen release by plant cells determined antigen release ...

  

Source: Hamill, John - School of Biological Sciences, Monash University

 

Collection: Biology and Medicine

 
53 original article 524 www.moleculartherapy.org vol. 17 no. 3, 524537 mar. 2009
 

Summary:  Society of Gene Therapy Recombinant adeno-associated virus (rAAV) expresses no viral genes after... - atal administration of rAAV expressing different transgenes, we used rAAV encoding two reliably... be immunologically benign due to a lack of antigen presentation. However, pre- exposure ...

  

Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida

 

Collection: Biology and Medicine

 
54 A Multi-Layered Immune Inspired Approach to Data Mining Thomas Knight and Jon Timmis
 

Summary:  -cells to antigenic stimulation. AINEs artificial immune networks were applied to unsupervised machine learning... if all patterns persist over time rather than the strongest. In parallel to the work in this paper [10... and antigens; the mechanisms that evaluate the interactions are antigenic binding ...

  

Source: Kent, University of - Computing Laboratory

 

Collection: Computer Technologies and Information Sciences

 
55 THEORETICAL ARTICLE Spatial modelling of brief and long interactions
 

Summary:  persistent behaviour. In the absence of antigen- bearing DCs they found cosf¼0.47, that is, a relatively... , T cells of appropriate antigen specificity become activated by antigen-presenting cells in secondary... decrease in T-cell motility after antigen appearance is due to `stop ...

  

Source: Utrecht, Universiteit - Departement Biologie, Theoretical Biology/Bioinformatics Group

 

Collection: Biology and Medicine

 
56 THEORETICAL ARTICLE Spatial modelling of brief and long interactions
 

Summary:  persistent behaviour. In the absence of antigen- bearing DCs they found cosf¼0.47, that is, a relatively... , T cells of appropriate antigen specificity become activated by antigen-presenting cells in secondary... decrease in T-cell motility after antigen appearance is due to `stop ...

  

Source: Beltman, Joost - Departement Biologie, Universiteit Utrecht

 

Collection: Biology and Medicine

 
57 A dynamical perspective of CTL cross-priming and regulation: implications for cancer immunology
 

Summary:  received attention in this respect. That is, CTL expansion occurs if antigen is recognized on the surface... of professional antigen presenting cells (APCs). This is in contrast to direct presentation where antigen is seen... established depends on the ratio of cross-presentation to direct presentation of the ...

  

Source: 

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
58 Activating B Cell Signaling with Defined Multivalent Erik B. Puffer
 

Summary:  are medi- ated through antigen interactions with the B cell antigen receptor (BCR). Antigen valency... polymerization (ROMP). When mice are injected with multivalent antigens generated by ROMP, only those of high... immune responses in vivo. All of the multiva- lent antigens tested ...

  

Source: Kiessling, Laura - Departments of Chemistry & Biochemistry, University of Wisconsin at Madison

 

Collection: Chemistry ; Biology and Medicine

 
59 MOLECULAR AND CELLULAR BIOLOGY, June 2008, p. 40404051 Vol. 28, No. 12 0270-7306/08/$08.00 0 doi:10.1128/MCB.00136-08
 

Summary:  Antigen Quantity and Quality Determine T-Cell Decisions in Lymphoid Tissue Huan Zheng,1 Bo Jin,1 Sarah E... ) molecules on their surface that can recognize peptides (p) derived from antigenic proteins bound to products... of the major histocompatibility complex (MHC) genes. The pMHC molecules are expressed on the surface of ...

  

Source: von Andrian, Ulrich H. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
60 T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for
 

Summary:  experiments have shown that even transient encounters trigger persistent antigen- dependent calcium fluxes... T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets... of cognate peptide and major histocompatibility complex (pMHC) per DC and with the density of antigen

  

Source: von Andrian, Ulrich H. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine


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61 Capturing escape in infectious disease Sarah Cobey1
 

Summary:  ) Chaos, persistence, and evolution of strain structure in antigenically diverse infectious agents... that are influenced by antigenic evolution. Recent findings indicate that many pathogens escape immunity... through rapid antigenic evolution. Their evolution allows them to reinfect previously immune ...

  

Source: 

 

Collection: Biology and Medicine

 
62 J. theor. Biol. (2002) 219, 153175 doi:10.1006/yjtbi.3079, available online at http://www.idealibrary.com on
 

Summary:  during the reaction. We show that antigen masking by antibodies which are produced by emerging plasma... against variations in the initial antigen amount over several orders of magnitude. This provides... a possible answer to the long-standing question of the role of antigen reduction in driving affinity

  

Source: Maini, Philip K. - Centre for Mathematical Biology & Mathematical Institute, University of Oxford

 

Collection: Mathematics ; Biology and Medicine

 
63 TheJournalofExperimentalMedicine www.jem.org/cgi/doi/10.1084/jem.20052056 Cite by DOI: 10.1084/jem.20052056 1 of 12
 

Summary:  -called inducible T reg cells or antigen-speci c T reg cells), and some of which are considered natu- rally... - ognize self-antigen. Whether they also recog- nize foreign antigens and the extent of their repertoire... for such antigens remain unknown. We and others have shown that natural T reg cells also ...

  

Source: Arnold, Jonathan - Nanoscale Science and Engineering Center & Department of Genetics, University of Georgia

 

Collection: Biotechnology

 
64 TheJournalofExperimentalMedicine J. Exp. Med. The Rockefeller University Press 0022-1007/2004/10/847/10 $8.00
 

Summary:  The adaptive immune response is initiated in secondary lymphoid organs by contact between antigen... -bearing dendritic cells (DCs) and antigen-specific CD4 T cells. However, there is scant information regarding... . In the first 2 h after entry into lymph nodes, T cells made short-lived contacts with antigen-bearing DCs, each

  

Source: Parker, Ian - Department of Neurobiology and Behavior, University of California, Irvine

 

Collection: Biology and Medicine

 
65 INFECTION AND IMMUNITY, Apr. 2008, p. 17741780 Vol. 76, No. 4 0019-9567/08/$08.00 0 doi:10.1128/IAI.01629-07
 

Summary:  . Mancuso, J. B. Weinberg, and J. G. Younger. 2007. Lipopolysaccharide O-antigen promotes persistent murine... .1128/IAI.01629-07 Copyright © 2008, American Society for Microbiology. All Rights Reserved. O Antigen... , produces an O antigen, a factor shown in other models to confer serum resistance. Using a ...

  

Source: Andrews, Anne M. - Huck Institutes of the Life Sciences, Pennsylvania State University

 

Collection: Biology and Medicine

 
66 Isolation of engineered, full-length antibodies from libraries
 

Summary:  fluorescently labeled antigen, are selected using flow cytometry. Screening of a library constructed from... an immunized animal yielded several antibodies with nanomolar affinities toward the protective antigen... of Bacillus anthracis. Monoclonal antibodies with desired antigen specificities are isolated using hybridoma

  

Source: Georgiou, George - Departments of Biomedical Engineering, & Chemical Engineering, University of Texas at Austin

 

Collection: Engineering ; Biotechnology

 
67 ANRV338-IY26-19 ARI 20 December 2007 15:54 Choreography of Cell
 

Summary:  reserved 0732-0582/08/0423-0585$20.00 Key Words T cell, B cell, dendritic cell, chemokine, antigen... , antigen recognition, and cell signaling and activation are clearly vital during an immune response... to basal motility of lymphocytes in the lymph node and cellular interactions leading to antigen capture

  

Source: Parker, Ian - Department of Neurobiology and Behavior, University of California, Irvine

 

Collection: Biology and Medicine

 
68 BASIS: A Biological Approach to System Information Security Victor A. Skormin1
 

Summary:  substances (or antigens as they are called), distinguish self from non-self, and show a heightened and rapid... memory response with each subsequent encounter with the antigen. The humeral immune response has... classically been defined as a response of the body to foreign antigens by producing large amounts of ant

  

Source: Delgado-Frias, José G. - School of Electrical Engineering and Computer Science, Washington State University

 

Collection: Computer Technologies and Information Sciences

 
69 vol. 176, no. 4 the american naturalist october 2010 Critical Interplay between Parasite Differentiation,
 

Summary:  -block cross-reactivity, there are cases when later antigenic blocks can persist more easily ( smaller... Differentiation, Host Immunity, and Antigenic Variation in Trypanosome Infections E. Gjini,1,2,* D. T. Haydon,2... chronic infection. Motivated by the growing knowledge on the antigenic variation system ...

  

Source: Cobbold, Christina - Department of Mathematics, University of Glasgow

 

Collection: Biology and Medicine ; Mathematics

 
70 Evolutionary origin on HIV zThe closest relatives of HIV-1 and HIV-2
 

Summary:  threshold Time Virus load #12;Antigenic variation ni ,...,1= virus mutant i immune response against mutant i... over time. #12;Antigenic variation Total virus load is proportional to antigenic diversity. cp br nvv i... i == : #12;Antigenic variation ni ,...,1= virus mutant i specific immune response cross ...

  

Source: Moehlis, Jeff - Department of Mechanical and Environmental Engineering, University of California at Santa Barbara

 

Collection: Physics

 
71 Correlates of cytotoxic T-lymphocyte-mediated virus control: implications for immuno-
 

Summary:  that cytotoxic T- lymphocyte (CTL) memory, de¢ned as antigen-independent persistence of CTL precursors... Figure 1. Antigen-independent long-term persistence of CTL precursors (CTLp) contributes to virus... of antigen can lead to virus persistence in the presence of ...

  

Source: Nowak, Martin A. - Department of Organismic and Evolutionary Biology, Harvard University

 

Collection: Environmental Sciences and Ecology

 
72 Mini-Review: Innate responses of B cells
 

Summary:  to antibody production, B cells also present antigen to Tcells, programme Tcell differentiation and regulate... and often antigen-nonspecific functions is important at a time when there is an increasing use of B cell... complex and diverse than simply making antibodies. B cells present antigen to T cells and then via

  

Source: 

 

Collection: Biology and Medicine

 
73 INFECTION AND IMMUNITY, Apr. 2004, p. 24202424 Vol. 72, No. 4 0019-9567/04/$08.00 0 DOI: 10.1128/IAI.72.4.24202424.2004
 

Summary:  . Effect of Growth State on Transcription Levels of Genes Encoding Major Secreted Antigens of Mycobacterium... and nonreplicating tubercle bacilli have different antigen compositions. The seminal finding that live Mycobacterium... ), the antigen 85 complex (Ag85A, Ag85B, and Ag85C) (42), encoded by the fbpA, fbpB, and fbpC genes, ...

  

Source: Kramer, Fred - Public Health Research Center, International Center for Public Health, University of Medicine and Dentistry of New Jersey

 

Collection: Biology and Medicine

 
74 Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates
 

Summary:  antigen-specific conjugates that were tracked, at least 15% (12/81) persisted Figure 6. Dynamics... activation that persists for Figure 7. Contact Times of Antigen-Engaged B cell­Helper T Cell Conjugates (A... of the conjugates persisted for at least 40 min, and some for longer than 80 ...

  

Source: Parker, Ian - Department of Neurobiology and Behavior, University of California, Irvine

 

Collection: Biology and Medicine

 
75 doi: 10.1098/rsif.2010.0007 , 1257-1274 first published online 24 March 201072010J. R. Soc. Interface
 

Summary:  duration of infection, however, two distinct lineages emerge and persist, with antigenic clusters replacing... antigenic protein (tier 2). This separ- ation of phenotypic dynamics from genetic dynamics results... & Grenfell 2009). In the case of antigenically variable viruses, these `phylodynamic' models ...

  

Source: Schluter, Dolph - Department of Zoology, University of British Columbia

 

Collection: Environmental Sciences and Ecology

 
76 Vaccine 27 (2009) 30133021 Contents lists available at ScienceDirect
 

Summary:  the Toll-like receptor (TLR) and NLRP3 in antigen-presenting cells. Here we present a class... with antigen. We demonstrate that LPS-modified particles are preferentially internalized by dendritic cells... encephalitis. The design of such an antigen delivery mechanism with the ability to stimulate two potent innate

  

Source: Fahmy, Tarek - Departments of Biomedical Engineering & Chemical and Environmental Engineering, Yale University

 

Collection: Materials Science ; Biology and Medicine

 
77 TheJournalofExperimentalMedicine J. Exp. Med. The Rockefeller University Press 0022-1007/2003/05/1233/12 $8.00
 

Summary:  1233 Antigen-capturing Cells Can Masquerade as Memory B Cells Jennifer Bell and David Gray Institute... cytometry method to identify antigen-specific cells. After immunization with PE, we could detect B220 and... , as reported previously, B220 antigen-bind- ing cells (McHeyzer-Williams, L.J., M. Cool, and M.G. Mc

  

Source: 

 

Collection: Biology and Medicine

 
78 Photoperiod controls the induction, retention, and retrieval of antigen-specific immunological memory
 

Summary:  the encoding, retention, and activation of antigen-specific immu- nological memory. The persistence of KLH... Photoperiod controls the induction, retention, and retrieval of antigen-specific immunological... the induction, retention, and retrieval of antigen- specific immunological memory. Am J Physiol Regul ...

  

Source: Nelson, Randy J. - Department of Psychology, Ohio State University

 

Collection: Biology and Medicine

 
79 INFECTION AND IMMUNITY, July 2008, p. 32213232 Vol. 76, No. 7 0019-9567/08/$08.00 0 doi:10.1128/IAI.01677-07
 

Summary:  of Multiple Genetic Polymorphisms on Antigen Presentation and Susceptibility to Mycobacterium tuberculosis... /Accepted 16 April 2008 Several molecules related to antigen presentation, including gamma interferon (IFN... a mathematical model of antigen presentation based on experimental data for the known effects of genetic

  

Source: Kirschner, Denise - Department of Microbiology and Immunology, University of Michigan

 

Collection: Biology and Medicine

 
80 J. theor. Biol. (1998) 191, 451462 00225193/98/080451 + 12 $25.00/0/jt970617 7 1998 Academic Press Limited
 

Summary:  on the evolution of antigenic variation, increasing replication rates and increasing virus load. We find... that target cell limitation provides a selection pressure against antigenic diversification, and can therefore... provide a limit to diversity. Antigenic diversity increases virus load; at the maximum level of ...

  

Source: Nowak, Martin A. - Department of Organismic and Evolutionary Biology, Harvard University

 

Collection: Environmental Sciences and Ecology


Page:   1  2  3  4  5 
Page:   1  2  3  4  5 
 
81 (and probably the SKR) was greatly facilitated by the fact that it
 

Summary:  , and mechanisms for latency and persistence in viral infections ofthe nervous system. The meetingwas highlighted... Humoral and cellular immune responses directed against self antigens are recognizedsequelae of exposure... with a variety of common viruses also react with antigens found in human tissues6. Proliferation of such ...

  

Source: Columbia University - Jerome L. and Dawn Greene Infectious Disease Laboratory

 

Collection: Biology and Medicine

 
82 This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research
 

Summary:  from whole microorganisms to subunit vac- cines that contain only their antigenic proteins. Subunit... response, ideally establishing both innate and adaptive immunity. Incorporation of antigens... immune cells. Targeting antigen to immune cells via PAMP-modified biomaterials is a new strategy

  

Source: Fahmy, Tarek - Departments of Biomedical Engineering & Chemical and Environmental Engineering, Yale University

 

Collection: Materials Science ; Biology and Medicine

 
83 Lymphocyte activation Editorial overview
 

Summary:  -cell immunity. These authors put forward the provocative concept that persistent antigen maintains local... responses are characterized by the capacity to recognize and remember pathogen-specific antigens. When... a cognate antigen is encountered, lymphocytes become activated, undergo clonal proliferation ...

  

Source: von Andrian, Ulrich H. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
84 Leon and Engman The Contribution of Autoimmunity to Chagas Heart
 

Summary:  -reactive lymphocytes, (iii) altered antigen processing leading to the generation and presentation of "cryptic self... ; Kierszenbaum, 1999), an immune reaction against self antigens causing tissue inflammation or cellular damage... and Engman98 host antigens may be a consequence and not a cause of tissue injury. To unequivocally ...

  

Source: Engman, David M. - Departments of Pathology & Microbiology-Immunology, Northwestern University

 

Collection: Biology and Medicine

 
85 In vivo imaging of germinal centres reveals a dynamic open structure
 

Summary:  maturation. Three to four antigen-specific B cells colonize a follicle to establish a germinal centre... centre, which is rich in antigen-trapping follicular dendritic cells and CD41 T cells5­7 . It has been... antigen5­8 . However, there have been no studies of germinal-centre dynamics or the migratory behaviour

  

Source: Shakhar, Guy - Department of Immunology, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
86 Immunology Letters 92 (2004) 107115 Dendritic cells in the initiation of immune responses against
 

Summary:  central nervous system-derived antigens Jozsef Karman, Changying Ling, Matyas Sandor, Zsuzsa Fabry... Avenue, Madison, WI 53706, USA Received 10 September 2003; accepted 21 October 2003 Abstract Antigen... presentation is essential for the activation and maintenance of antigen-specific T cell responses

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
87 Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-
 

Summary:  Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus... antigen-specific T cells in vivo. In this system, clonal naive T cells with defined antigen specificity... are generated by retrovirus- mediated expression of T cell antigen receptor cDNAs in RAG1- deficient ...

  

Source: Baltimore, David - Division of Biology, California Institute of Technology

 

Collection: Biotechnology ; Biology and Medicine

 
88 Erin R Steenblock, Stephen H Wrzesinski, Richard A Flavell & Tarek M Fahmy Yale University, Malone Engineering Center, New Haven, CT, USA
 

Summary:  elucidated principles that can be used for a bottom-up approach to engineering artificial antigen... presentation on synthetic substrates. Objective/methods: To compare the latest artificial antigen... for adoptive immunotherapy. Keywords: adoptive cell transfer, artificial antigen-presenting cell, cancer

  

Source: Fahmy, Tarek - Departments of Biomedical Engineering & Chemical and Environmental Engineering, Yale University

 

Collection: Materials Science ; Biology and Medicine

 
89 Recombinant Adeno-associated Viral Vectors as Therapeutic Agents to Treat Neurological Disorders
 

Summary:  plaques through- out the brain without the necessity of injecting vector into the brain. rAAV expressing... and the genome persists in an episomal form [9,10]. One clear limitation of rAAV is that the transgene... of function [29,30]. When similar experiments were done in nonhuman primates, striatal injections of ...

  

Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida

 

Collection: Biology and Medicine

 
90 Transgenic Research 9: 127135, 2000. 2000 Kluwer Academic Publishers. Printed in the Netherlands.
 

Summary:  induces the prolif- eration of more antigen-specific memory B cells and results in a more persistent... to inactivated RSV antigen. Introduction Respiratory syncytial virus (RSV) is an enveloped virus of the genus... ) response (Srikiatkhachorn and Braciale, 1997a). Oral exposure to particulate and replicating ...

  

Source: Korban, Schuyler S. - Department of Natural Resources and Environmental Sciences, University of Illinois at Urbana-Champaign

 

Collection: Biotechnology

 
91 INDUCTION OF ANTIGEN SPECIFIC TOLERANCE TO BONE MARROW ALLOGRAFTS WITH CD4+
 

Summary:  - 1 - INDUCTION OF ANTIGEN SPECIFIC TOLERANCE TO BONE MARROW ALLOGRAFTS WITH CD4+ CD25... for their activation, but once activated they act in an antigen-non-specific manner. In vivo, regulatory T cells... are also activated in an antigen-specific fashion, but nothing is known about antigen

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
92 Regulatory T cell adjustment of quorum growth thresholds and the control of local immune responses.
 

Summary:  to their specific antigen, conventional T cells are activated leading to secretion of growth cytokines... is not T cell specific, i.e. Tregs inhibit all conventional T cells independent of their antigen specificity... such an invasion, T cells specific to the antigen proliferate and under most circumstances successfully remove

  

Source: Burroughs, Nigel - Mathematics Institute, University of Warwick

 

Collection: Mathematics

 
93 An Antigenic Threshold for Maintaining Human Immunodeficiency Virus Type 1-specific Cytotoxic
 

Summary:  memory to lymphocytic choriomeningitis virus is governed by persist- ing antigen. J. Exp. Med. 176: 1273... An Antigenic Threshold for Maintaining Human Immunodeficiency Virus Type 1-specific Cytotoxic... that memory cytotoxic T-lymphocyte (CTL) responses are maintained in the presence of continuous antigenic

  

Source: Bonhoeffer, Sebastian - Institut für Integrative Biologie, Eidgenössische Technische Hochschule Zürich (ETHZ)

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
94 Virus Research 104 (2004) 123127 Susceptibility of peritoneal macrophages to
 

Summary:  results in rapidly fatal encephalitis, while low-neurovirulence BeAn and DA viruses produce persistent... virus antigen(s) and contained nicked DNA indicative of apoptosis. However, BeAn virus RNA replication... but negative for virus RNA and antigen(s). Tumor necrosis factor- (TNF- ) and interferon- (IFN- ) were elevated

  

Source: Lipton, Howard L. - Department of Microbiology and Immunology, University of Illinois at Chicago

 

Collection: Biology and Medicine

 
95 Immunity, Vol. 6, 419428, April, 1997, Copyright 1997 by Cell Press Different Nuclear Signals Are
 

Summary:  cells that bear a uniform BCR specific for the Richard S. Lewis, and Christopher C. Goodnow*§ antigen... acute exposure Department of Molecular and Cellular Physiology to the foreign HEL antigen (Cooke et al... is chronically encountered as a self- Washington University School of Medicine antigen, antigen ...

  

Source: Dolmetsch, Ricardo E. - Department of Neurobiology, Stanford University

 

Collection: Biology and Medicine

 
96 INFECTION AND IMMUNITY, Mar. 2008, p. 12141222 Vol. 76, No. 3 0019-9567/08/$08.00 0 doi:10.1128/IAI.01208-07
 

Summary:  acute and persistent LCMV infections (11). In conclusion, the LT-based antigen delivery system... .1128/IAI.01208-07 Copyright © 2008, American Society for Microbiology. All Rights Reserved. Antigen... with these LT-antigen fusion proteins leads to the induction of antigen- specific CD8 ...

  

Source: Starnbach, Michael - Department of Microbiology and Molecular Genetics, Harvard University

 

Collection: Biology and Medicine

 
97 500 VOLUME 12 NUMBER 6 JUNE 2011 nature immunology r e v i e w i m m u n o l o g i c a l m e m o ry
 

Summary:  , adoptively transferred memory NK cells persist in naive hosts and retain antigen specificity for at least 4... they can persist for many months. During the memory phase, antigen-specific NK cells may be released from... recombinase to generate a multitude of T cell antigen receptors and ...

  

Source: von Andrian, Ulrich H. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
98 Immunisation of mice against neosporosis Anna Lundena,*, Stephen Wrightb
 

Summary:  tachyzoites, N. caninum antigens incorporated into iscoms, N. caninum lysate mixed with Quil A, or N. caninum... or by immu- nisation with parasite antigens. The antigens were either incorporated in immune stimulating... of mice and to prepare the different antigen preparations used for immunisation and ...

  

Source: Allen, Judith - School of Biological Sciences, University of Edinburgh

 

Collection: Biology and Medicine

 
99 Proliferation responses to HIVp24 during antiretroviral therapy do not reflect improved immune phenotype or
 

Summary:  ¼ 18) LP to HIV-core antigen. The two groups were compared for functional immune responses... ,17­19]. Some patients receiving antire- troviral therapy (ART) develop strong CD4+ T-cell LP responses to HIV-antigens... function. We found that emerging LP re- sponses to HIV-1 core antigen in persons with ART- induced control

  

Source: Lieberman, Judy - Immune Disease Institute, Harvard University

 

Collection: Biology and Medicine

 
100 JOURNAL OF VIROLOGY, Sept. 1996, p. 63956401 Vol. 70, No. 9 0022-538X/96/$04.00 0
 

Summary:  specifically, the presence of viral antigens in some of the MAP-2-positive cells suggests that PV can persist... . The presence of viral antigens in postmitotic neurons is in agreement with PV being able to persist... , American Society for Microbiology Persistent Poliovirus Infection of ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics


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