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Sample search results for: a-receptor blockade attenuates

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1 Interaction Between Nitric Oxide and Endogenous Vasoconstrictors in Control of Renal Blood Flow
 

Summary:  FE, Newby DE, Cruden NL, Koomans HA, Rabelink TJ, Webb DJ. Endothelin-A receptor antagonist... in normotensive dogs, we found that combined blockade of endothelin type A (ETA) receptors and angiotensin II... different experimental treatments on separate days. Blockade of ETA receptors alone by the selective

  

Source: Just, Armin - Physiologisches Institut I, Albert-Ludwigs-Universität Freiburg

 

Collection: Biology and Medicine

 
2 PET Imaging of Serotonin 1A Receptor Binding in Depression
 

Summary:  PET Imaging of Serotonin 1A Receptor Binding in Depression Wayne C. Drevets, Ellen Frank, Julie C... Background: The serotonin-1A (5HT1A) receptor system has been implicated in the pathophysiology of major... . This literature is in disagreement, however, regarding the brain regions where ...

  

Source: Morris, Evan - Purdue School of Engineering and Technology & Department of Radiology, Indiana University-Purdue University Indianapolis

 

Collection: Engineering ; Biology and Medicine

 
3 Summary and conclusions Summary and Conclusions
 

Summary:  administration of the 5-HT1A receptor agonist 8-OH-DPAT was attenuated, which suggests desensitisation... of auto-regulation. Presynaptic 5-HT1A receptors are involved in a feedback mechanism that is localized... 5-HT1A receptor antagonist or a ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
4 Antisense Inhibition of 5-Hydroxytryptamine2a Receptor Induces an Antidepressant-Like Effect in Mice
 

Summary:  treatment selectively down-reg- ulates 5-HT2A receptor levels and attenuates receptor function. In the brain... that blockade of the 5-HT2A receptor can lead to an anti-immobility effect (Fig. 3B). The anti-immobility effect... of AS oligonucleotide injection was ...

  

Source: Sibille, Etienne - Center for the Neural Basis of Cognition & Department of Psychiatry, University of Pittsburgh

 

Collection: Biology and Medicine

 
5 Acute and Chronic Effects of Citalopram on Postsynaptic 5-Hydroxytryptamine1A (5-HT1A) Receptor Mediated Feedback: A Microdialysis Study in the Amygdala
 

Summary:  extracellular 5-HT in the amygdala to 175% of basal level (Table 2)(Fig. 4). Blockade of 5-HT1A receptors... Acute and Chronic Effects of Citalopram on Postsynaptic 5-Hydroxytryptamine1A (5-HT1A) Receptor... of Citalopram on Postsynaptic 5-Hydroxytryptamine1A (5-HT1A) ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
6 Behavioral/Systems/Cognitive Contribution of 5-HT2 Receptor Subtypes to
 

Summary:  blockade of 5-HT2A receptors in 5-HT2A / mice. Key words: serotonin; sleep; mice; 5-HT2 receptors; sleep... time and conditions (baseline vs sleep deprivation). Results 5-HT2A receptor blockade by MDL 100907... of that obtained after blockade of ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
7 5-HT1A receptor gene expression and binding in the brain The two left pictures show 5-HT1a receptor gene expression in a brain slice of a LAL
 

Summary:  5-HT1A receptor gene expression and binding in the brain The two left pictures show 5-HT1a receptor... than in the SAL mouse. The two right pictures show 5-HT1A receptor binding with 3 H-8-OH- DPAT... in a brain slice of a LAL (upper right picture) and a SAL mouse ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
8 Behavioral/Systems/Cognitive Layer II/III of the Prefrontal Cortex: Inhibition by the
 

Summary:  blockade of 5-HT1A receptors during postnatal development (Lo Iacono and Gross, 2008). These results... -HT1A Receptor in Development and Stress Nathalie M. Goodfellow,1 Madhurima Benekareddy,3 Vidita A... ,asexdifferenceinthese currents emerges, consistent with human imaging studies of ...

  

Source: Vaidya, Vidita - Department of Biological Sciences, Tata Institute of Fundamental Research

 

Collection: Biology and Medicine

 
9 Pharmacological evaluation of selected arylpiperazines with atypical antipsychotic potential
 

Summary:  at D2, 5-HT2A and a1 receptors and a higher affinity for 5-HT1A receptors than clozapine. Also... in development of this disease.2;4 It was hypothesized that antagonism of D2 and 5-HT2A receptors and enhancement... as an atypical antipsy- chotic.5 Besides the accentuated role of the ...

  

Source: Champagne, Frances A. - Department of Psychology, Columbia University

 

Collection: Biology and Medicine

 
10 Effect of a P-Glycoprotein Inhibitor, Cyclosporin A, on the Disposition in
 

Summary:  of the 5-HT1A Receptor Radioligand, [11 C](R)-(­­)-RWAY JEIH-SAN LIOW,* SHUIYU LU, JULIE A. Mc... -glycoprotein; [11 C](R)-(À)-RWAY; 5-HT1A receptors ABSTRACT Limited brain uptake of radioligands with otherwise... of [11 C](R)-(À)-RWAY, a radioligand for brain 5-HT1A ...

  

Source: Pike, Victor W. - Molecular Imaging Branch, National Institute of Mental Health

 

Collection: Biology and Medicine

 
11 5-HT2A Receptor-Mediated Regulation of Brain-Derived Neurotrophic Factor mRNA in the Hippocampus and the Neocortex
 

Summary:  in piriform cortex by 5-hydroxytryptamine: blockade by MDL 100,907, a highly selective 5-HT2A receptor... 5-HT2A Receptor-Mediated Regulation of Brain-Derived Neurotrophic Factor mRNA in the Hippocampus... , but not a 5-HT1A receptor agonist, ...

  

Source: Vaidya, Vidita - Department of Biological Sciences, Tata Institute of Fundamental Research

 

Collection: Biology and Medicine

 
12 Psychedelic drugs have long held a special fascination for mankind because they pro-
 

Summary:  of serotonin (5-hydroxytryptamine) 2A (5-HT2A ) receptors12 and mimic mainly the so- called positive symptoms... in the US Demonstration of agonistic action of LSD at 5-HT2A receptors; first neuroimaging study... actions at cortical 5-HT2A receptors (FiG. 1a). ...

  

Source: Alford, Simon - Department of Biological Sciences, University of Illinois at Chicago

 

Collection: Biology and Medicine

 
13 This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research
 

Summary:  receptor function [10,32]. Adenosine type A1 and A2A receptors on glutamatergic terminals play a critical... -inflammatory influence of A2A receptor activation to proinflammatory [8]. Caffeine is an antagonist at both adenosine... type A1 and A2A receptors and ...

  

Source: Wenk, Gary - Departments of Psychology & Neuroscience, Ohio State University

 

Collection: Biology and Medicine

 
14 No evidence for cross-talk between the adenosine A1 and the serotonin-1A receptor system after chronic A1 receptor
 

Summary:  Chapter 7 No evidence for cross-talk between the adenosine A1 and the serotonin-1A receptor system... a desensitization of the receptor system. Nevertheless, the hypothermic response to the serotonin-1A receptor... CPA desensitizes the adenosine A1 receptor system but it does not alter serotonin- ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
15 18 Review article Mutant mouse models and antidepressant drug research
 

Summary:  that 5-HT1A receptor protein and mRNA levels were significantly decreased in the dorsal raphe nucleus... (DRN; presynaptic 5-HT1A receptors) and increased in the hippocampus (postsynaptic 5-HT1A receptors... or partially reversed by a 5-HT synthesis inhibitor, ...

  

Source: Kalueff, Allan V. - Department of Pharmacology, Tulane University

 

Collection: Biology and Medicine

 
16 Augmentation with a 5-HT1A, but not a 5-HT1B receptor antagonist critically depends on the dose of citalopram Augmentation with a 5-HT1A, but not a 5-HT1B
 

Summary:  on extracellular 5-HT, while the 5- HT1A receptor antagonist was no longer effective. These results suggest... strategies with 5-HT1A receptor antagonists in the therapy of depression and anxiety disorders. #12... of the 5-HT1A receptor agonist 8-hydroxy-2- ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
17 In The News Friday, October 15, 2010
 

Summary:  - Online View Clip Blockade of nerve sprouting and neuroma formation markedly attenuates the development

  

Source: Arizona, University of - Center for Gamma-Ray Imaging

 

Collection: Engineering ; Biology and Medicine

 
18 Shunting and Hyperpolarizing GABAergic Inhibition in the High-Potassium Model of Ictogenesis
 

Summary:  development, depolarizing GABA also exerts anticonvulsive actions. Blockade of GABA(A) receptors induces... of ictal discharges (not shown). However, blockade of GABA(A) receptors increased nearly 5-fold... -like recurrent events. Blockade of ...

  

Source: Cossart, Rosa - Institut de Neurobiologie de la Méditerranée, Inserm

 

Collection: Biology and Medicine

 
19 Genetics of caffeine consumption and responses to caffeine Amy Yang & Abraham A. Palmer & Harriet de Wit
 

Summary:  , but animal studies have shown that A2A receptor blockade protects against ischemia neuronal injuries... and A2A receptors (Daly et al. 1983). Adenosine receptors are G-protein-coupled receptors locat- ed... 1 and A2A receptors are especially ...

  

Source: Das, Soma - Department of Human Genetics, University of Chicago; Ober, Carole - Committee on Genetics & Department of Human Genetics, University of Chicago

 

Collection: Biology and Medicine

 
20 Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related
 

Summary:  anxiety, enhanced firing of 5-HT neurons, and attenuation of presynaptic 5-HT1A receptor function... by desensitization of the autoreg- ulatory presynaptic 5-hydroxytriptamine (5-HT) 1A receptor. Similar alterations... in DR and 5-HT1A receptor ...

  

Source: Sibille, Etienne - Center for the Neural Basis of Cognition & Department of Psychiatry, University of Pittsburgh

 

Collection: Biology and Medicine


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21 The behavioral pharmacology of hallucinogens William E. Fantegrossi a,
 

Summary:  ). All of these drugs function as agonists at 5-HT2A receptors, and much work has culminated... 's affinity for 5-HT2A receptors [18,30]. The observation of drug-elicited behaviors can be immen- sely... of the hallucinogenic drugs, and there is now general agreement that this behavior is mediated by ...

  

Source: Howell, Leonard L. - Yerkes National Primate Research Center, Emory University

 

Collection: Biology and Medicine

 
22 SSRI augmentation strategies; pharmacodynamic and pharmacokinetic
 

Summary:  on Postsynaptic 133 5-Hydroxytryptamine1A(5-HT1A) Receptor Mediated Feedback: A Microdialysis Study... for 5-HT3), the 5-HT1A receptor is a member of the 7 transmembrane G-protein coupled receptor (7-TM GPCR... decreasing their susceptibility to depolarise. Overall, the 5-HT1A ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
23 Vasopressin (V1a) Receptor Binding, mRNA Expression and Transcriptional Regulation by Androgen in the Syrian Hamster Brain
 

Summary:  Vasopressin (V1a) Receptor Binding, mRNA Expression and Transcriptional Regulation by Androgen... distribution of vasopressin (V1a) receptor mRNA and V1a receptor binding. V1a receptor mRNA and binding... hypothalamus. ...

  

Source: Wang, Zuoxin - Department of Psychology, Florida State University

 

Collection: Biology and Medicine

 
24 POTENTIATION OF THE RESETTING EFFECTS OF LIGHT ON CIRCADIAN RHYTHMS OF HAMSTERS USING SEROTONIN
 

Summary:  as antagonists at post- synaptic 5-HT1A receptors, for example, in the suprachias- matic nuclei... at postsynaptic 5-HT1A receptors, can potentiate circadian responses to light (Rea et al., 1995). Three compounds... (BMY 7378, S 15535, and MDL 73005 EF), all agonists at presynaptic ...

  

Source: Harrington, Mary - Department of Psychology, Smith College

 

Collection: Biology and Medicine

 
25 Augmentation strategies to improve the effect of SSRIs in the treatment of depression Augmentation strategies to improve the effect of
 

Summary:  and 5-HT1A receptor antagonism As mentioned above, following SSRI administration there is a certain... of somatodenedritic 5-HT1A receptors leading to disinhibition in the regulation of extracellular 5-HT (Blier & De... ). These compounds displayed similar or better potency at the 5- ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
26 Topical differences in serotonergic autoreceptor control; effects of chronic treatment with citalopram Topical differences in serotonergic autoreceptor
 

Summary:  with the 5-HT1A receptor antagonist Way 100635 or the 5-HT1B/D receptor antagonist GR 127935 were used... of autoreceptors. At low doses of citalopram the 5-HT1A receptor played the most prominent role, however at higher... neurotransmission is subject to several auto-inhibitory processes. Activation of ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
27 Myoclonus and Paroxysmal Dyskinesias, Advances in Neurology, Vol. 99, edited by S.
 

Summary:  activity despite using relatively high micromolar concentrations. These included the 5-HT1A receptor... . 28.5. The high affinity 5-HT1A receptor antagonist NAN-190 reversibly blocked synchronous motor... ) oscillations among motoneurons in the presence of glycine receptor blockade; he ...

  

Source: Manitoba, University of - Spinal Cord Research Centre

 

Collection: Biology and Medicine

 
28 European Neuropsychopharmacology 11 (2001) 413421 www.elsevier.com/locate/euroneuro
 

Summary:  -HT1A receptor is used as a model of gene product with complex functions and distributions... . Recent developments in1A receptors are expressed in the somatodendritic compart- DNA microarray... transgenic mice1A receptor. In the present design, a DNA sequence ...

  

Source: Sibille, Etienne - Center for the Neural Basis of Cognition & Department of Psychiatry, University of Pittsburgh

 

Collection: Biology and Medicine

 
29 Frontiers in Cellular Neuroscience www.frontiersin.org July 2010 | Volume 4 | Article 17 | 1 CELLULAR NEUROSCIENCE
 

Summary:  GDPsamplitude,desynchronizedneuronalfiringduringGDPsandsloweddown GDPs propagation. Partial blockade of GABA(A) receptors with bicuculline increased neuronal... , and the results were normalized to control values in each given slice. Partial blockade of GABA(A)receptors... of ...

  

Source: Cossart, Rosa - Institut de Neurobiologie de la Méditerranée, Inserm

 

Collection: Biology and Medicine

 
30 PII S0361-9230(01)00537-8 Age-associated changes in the serotonergic system in
 

Summary:  incubated with antibodies to serotonin, the serotonin 2A receptor, and the serotonin transporter. Immuno... of serotonin 2A receptor stain- ing in select layers of superior colliculus, and no change in serotonin... ,16,20,22,39,59]; in general, the serotonin 2A (5HT2A) ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
31 BI-DIRECTIONAL MODULATION OF BED NUCLEUS OF STRIA TERMINALIS NEURONS BY 5-HT: MOLECULAR EXPRESSION AND
 

Summary:  application of the 5-HT2A receptor antagonist MDL 100907 would attenuate the excitatory component of 5-HTHyp... is mediated by activation of postsynaptic 5-HT1A receptors. Here, we used a combination of in vitro whole... RT­PCR data revealed that 5-HT7 receptors (46%) and ...

  

Source: Rainnie, Donald "Tig" - Yerkes National Primate Research Center, Emory University

 

Collection: Biology and Medicine

 
32 doi:10.1152/physiolgenomics.00068.2005 23:89-102, 2005. First published Jul 26, 2005;Physiol. Genomics
 

Summary:  inactivation of adenosine A2A receptor reveals an Egr-2-mediated transcriptional regulatory network... Weng, and Jiang-Fan Chen. Genetic and pharmacological inactivation of adenosine A2A receptor reveals... ­102, 2005. First published July 26, 2005; 10.1152/physiolgenomics.00068.2005.--The adenosine ...

  

Source: Weng, Zhiping - Center for Advanced Genomic Technology, Boston University

 

Collection: Biotechnology

 
33 STUDIES ON THE ROLE OF THE N-TERMINAL DOMAIN OF NR1 IN THE REDOX MODULATION OF NR2A-CONTAINING NMDA RECEPTORS
 

Summary:  sites of action in this region of the receptor. NR1/NR2A receptors contain cysteines in the ATD of both... sensitivity of NR1/NR2A receptors remains largely unexplored. The goal of this dissertation was to explore... transiently potentiates NR1a(c744a,c798a)/NR2A ...

  

Source: Sibille, Etienne - Center for the Neural Basis of Cognition & Department of Psychiatry, University of Pittsburgh

 

Collection: Biology and Medicine

 
34 The response of neurons in the bed nucleus of the stria terminalis to serotonin: Implications for anxiety
 

Summary:  . Specifically, we have shown that the activation of 5HT1A receptors mediates an inhibitory response to 5-HT... in the BNST is to dampen neural activity via postsynaptic 5-HT1A receptor activation, which would consequently... release in the BNST preferentially acts on 5-HT1A ...

  

Source: Rainnie, Donald "Tig" - Yerkes National Primate Research Center, Emory University

 

Collection: Biology and Medicine

 
35 This article was downloaded by:[University College London] On: 1 July 2008
 

Summary:  as this opponency (for instance, 5-HT2A receptors in the striatum appear to boost the effects of dopamine), making... of responding in extinction, and critical effects of dopamine blockade, notably that subjects experiencing... shocks under dopamine blockade, and hence failing to avoid them, nevertheless ...

  

Source: Dayan, Peter - Gatsby Computational Neuroscience Unit, University College London

 

Collection: Biology and Medicine

 
36 CARDIOVASCULAROSCILLATIONS Autonomic Neural Control
 

Summary:  suggests that slow MABP oscil- lations are attenuated more efficiently. During ganglion blockade (both... during resting conditions is frequency dependent, with slow ABP changes being attenuated more effec... variations during autonomic ganglion blockade. Transfer function analysis revealed a significant ...

  

Source: Mitsis, Georgios - Department of Electrical and Computer Engineering, University of Cyprus

 

Collection: Engineering ; Biology and Medicine

 
37 Pharmacological characterization of serotonin receptor subtypes modulating primary aerent input to deep dorsal horn neurons in
 

Summary:  . This action was probably mediated by 5-HT1A receptor activation, since it occurred in the presence of the 5-HT... 7 receptor antagonist clozapine and was not observed in the presence of NAN-190, a 5-HT1A receptor... antagonist. In the absence of any agonist, 5-HT1A ...

  

Source: Hochman, Shawn - Department of Physiology, Emory University

 

Collection: Biology and Medicine

 
38 Miniature Neurotransmission Stabilizes Synaptic Function via Tonic Suppression
 

Summary:  that the miniature synaptic transmission that persists during AP blockade profoundly shapes the time course... and mechanism of ho- meostatic scaling. A brief blockade of NMDA receptor (NMDAR) mediated miniature synaptic... blockade alone. The rapid scaling induced by NMDAR mini blockade is mediated by ...

  

Source: Schuman, Erin M. - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
39 GENERAL DISCUSSION 138 Chapter 7
 

Summary:  , an attenuated responsiveness of postsynaptic 5-HT1A receptors in LAL mice was also found by measuring... .2.1. 5-HT1A receptor gene expression and function 2.2.2. 5-HT metabolism 2.3. Hippocampal plasticity 2... hypothalamic CRH and hippocampal dentate gyrus GR mRNA expression, and ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
40 Developmental changes in GABAergic actions and seizure susceptibility in the rat hippocampus
 

Summary:  a decrease in MUA) was estimated at postnatal day 13.5 Æ 0.4. Effect of blockade of the GABA(A) receptors... is correct, then blockade of GABA(A) receptors should alleviate the epileptiform activity. We therefore... studied the effect of ...

  

Source: Cossart, Rosa - Institut de Neurobiologie de la Méditerranée, Inserm

 

Collection: Biology and Medicine


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41 An investigation of the role of auditory cortex in sound localization using muscimol-releasing Elvax
 

Summary:  the cortex at the synaptic level by incorporating the g-aminobutyric acid (GABA)A receptor agonist muscimol... to be unaffected. Blockade of cortical neurons in the deeper layers was restricted to 500 mm from the edge... and requires the animal to be tethered. More persistent blockade can be achieved by ...

  

Source: Oxford, University of - University Laboratory of Physiology, Auditory Neuroscience Group

 

Collection: Biology and Medicine

 
42 Attenuation of SSRI-induced increases in extracellular brain 5-HT by benzodiazepines Attenuation of SSRI-induced increases in
 

Summary:  facilitates the effect of a challenge dose on cortical serotonin output: role of presynaptic 5-HT1A receptors... Attenuation of SSRI-induced increases in extracellular brain 5-HT by benzodiazepines 173 Chapter 8... Attenuation of SSRI-induced increases in extracellular brain 5-HT by benzodiazepines. ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
43 Brain and Whole-Body Imaging in Rhesus Monkeys of 11C-NOP-1A, a Promising PET Radioligand for
 

Summary:  concentration of 11C-NOP-1A peaked at approxi- mately 2 min and decreased quickly thereafter (Fig. 2A). Receptor... , was 15% 6 2% (n 5 4 blood samples). PET Scans PET scans at baseline and after NOP-receptor blockade were... was acquired at about 98­102 min after injection. All images were corrected for ...

  

Source: Innis, Robert B. - Molecular Imaging Branch, National Institute of Mental Health

 

Collection: Biology and Medicine

 
44 Differential binding properties of [3 H]dextrorphan
 

Summary:  /NR2A receptors was considerably slower than that for [3 H]dextrorphan. Glutamate individually... attenuated Mg2C blockade, while the double mutant NR1-1a (N616Q)/ NR2B (N616Q) was most effective... -1a/NR2A receptor (Table 1, Fig. 10A). High- affinity binding of [3 ...

  

Source: Traynelis, Stephen F. - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
45 GABAB and NMDA Receptors Contribute to Spindle-Like Oscillations in Rat Thalamus In Vitro
 

Summary:  conditions of low bath [Mg2 ] and/or GABAA receptor blockade, have been described. Here we show that faster... blockade of N-methyl-D-aspartate (NMDA) or -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA... rhythms that have been observed in other studies. The effects of GABAB or NMDA receptor blockade were more

  

Source: Huguenard, John R. - Department of Neurology and Neurological Sciences, Stanford University

 

Collection: Biology and Medicine

 
46 Adenosine A2A receptor in the monkey basal ganglia: ultrastructural localization and co-localization with the metabotropic glutamate receptor 5 in the striatum
 

Summary:  Title Page Adenosine A2A receptor in the monkey basal ganglia: ultrastructural localization and co... ; Accepted: Aug 12, 2011 #12;Abstract The adenosine A2A receptor (A2AR) is a potential drug target... ). Because of its localization and functional interaction with dopamine D2 receptors (D2R), the ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
47 ORIGINAL INVESTIGATION Neurochemical, behavioral, and physiological effects
 

Summary:  alterations in adult mice (Ansorge et al. 2008). Increased activation of 5-HT1A receptors by enhanced... by postsynaptic 5-HT1A receptors (Goodwin et al. 1987a, b, 1986; Lucki et al. 1984; Smith and Peroutka 1986... in mice, and as men- tioned, presynaptic 5-HT1A ...

  

Source: Murphy, Dennis L. - Laboratory of Clinical Science, National Institute of Mental Health

 

Collection: Biology and Medicine

 
48 NEUROBIOLOGICAL AND FUNCTIONAL CONSEQUENCES OF CHRONIC PARTIAL SLEEP DEPRIVATION
 

Summary:  that serotonin-1A receptor sensitivity can be attenuated by stress and elevated levels of glucocorticoids (Meijer... sleep restriction protocol might attenuate serotonin-1A receptor sensitivity by increased levels... -1A ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
49 Too little sleep gradually desensitizes the serotonin-1A receptor Viktor Romn, Irene Walstra, Paul G. M. Luiten, Peter Meerlo
 

Summary:  attenuate serotonin-1A receptor sensitivity by increased levels of stress hormones. In Experiment 1... -1A receptor-mediated hypothermic response was significantly attenuated (repeated measures ANOVA... attenuates serotonin-1A ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
50 Solid State Communications, Vol. 108, No. 11, pp. 839843, 1998 Pergamon c 1998 Elsevier Science Ltd. All rights reserved
 

Summary:  OF STRONG COULOMB BLOCKADE IN RESISTIVELY ISOLATED TUNNEL JUNCTIONS Wei Zheng1 , J.R. Friedman, D.V. Averin... measurements of the Coulomb-blockade current in resis- tively isolated (RIsol h/e2 ) tunnel junctions... 1998 Elsevier Science Ltd. All rights reserved Keywords: D. Coulomb blockade, D. Luttinger liquids, D

  

Source: Friedman, Jonathan R. - Department of Physics, Amherst College

 

Collection: Physics

 
51 Oxygen delivery is the most decisive factor in deter-mining necrosis or survival of ischaemic flaps.
 

Summary:  ,4 However, the hypothesis that sympa- thetic blockade improves flap perfusion lacks both experimental... tension in the microcirculation of ischaemic skin flaps after neural blockade and haemodilution D. Erni... , Switzerland SUMMARY. The aim of this study was to evaluate the effects of neural blockade and extended

  

Source: California at San Diego, University of - Department of Bioengineering, Microhemodynamics Laboratory

 

Collection: Biology and Medicine

 
52 Anesthesiology 2001; 95:14061413 2001 American Society of Anesthesiologists, Inc. Lippincott Williams & Wilkins, Inc. Ketamine Blockade of Voltage-gated Sodium Channels
 

Summary:  Williams & Wilkins, Inc. Ketamine Blockade of Voltage-gated Sodium Channels Evidence for a Shared Receptor... in a local anes- thetic­like fashion, exhibiting tonic blockade (concentration for half-maximal inhibition... [IC50] 0.8 mM), phasic blockade (IC50 2.3 mM), and leftward shift of the steady-state inactiva- tion

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
53 Behavioral Neuroscience 2001, Vol. 115, No. 4, 910-919
 

Summary:  a receptor antagonist in the lateral septum blocked mating-induced partner preference, whereas... mating or AVP administration, suggesting that the OT receptor blockade may have interfered with the AVP... a conspecific stranger (partner preference). In Experiment 1, we examined whether AVP Via receptor ...

  

Source: Contreras, Robert J. - Department of Psychology, Florida State University; Wang, Zuoxin - Department of Psychology, Florida State University

 

Collection: Biology and Medicine

 
54 Differential effects of chronic partial sleep deprivation and stress on serotonin-1A and muscarinic acetylcholine receptor sensitivity
 

Summary:  days of sleep restriction resulted in a significantly attenuated serotonin-1A receptor function... in postsynaptic serotonin-1A receptor sensitivity, whilst chronic forced activity alone, with sufficient sleep... shows that the serotonin-1A ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
55 A pharmacological analysis of mice with a targeted disruption of the serotonin transporter
 

Summary:  by 8-OH-DPAT in SERT +/+ and +/- mice, confirming me- diation by Htr1a receptors (Li et al. 1999... ). Given the known role of Htr1a receptors located in the paraventricular nucleus of the hypothalamus... , as rats administered fluoxetine daily evidenced a similar desensitization of Htr1a ...

  

Source: Andrews, Anne M. - Huck Institutes of the Life Sciences, Pennsylvania State University

 

Collection: Biology and Medicine

 
56 CCK ENHANCES RESPONSE TO GASTRIC DISTENSION BY ACTING ON CAPSAICIN -
 

Summary:  by the selective CCK-A receptor antagonist, lorglumide. We conclude that CCK directly activates capsaicin... appreciated. Richards et al. (28) found that administration of the CCK-A receptor antagonist, MK-329, blocked... -insensitive nerves, gastric distension and CCK selective CCK-A ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
57 Augmentation of SSRI effects on serotonin by 5-HT2C antagonists: mechanistic studies Augmentation of SSRI effects on serotonin by 5-
 

Summary:  . The blockade of 5-HT2C receptors would enhance the serotonergic activation of 5-HT2A receptors, which have been... ; Millan et al, 2000; Gobert et al, 1997, 1999; De Boer et al, 1996), 5-HT2A receptors (Szabo & Blier, 2002... ) Acute and chronic effects of citalopram on postsynaptic ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
58 RIJKSUNIVERSITEIT GRONINGEN Coping Style & Stressor Susceptibility
 

Summary:  proliferation in adult low and high aggressive mice Chapter 6 Differential effects of two 5-HT1A receptor... contains five receptor subtypes, of which the 5-HT1A receptors are widely distributed throughout the brain... . In the raphe nuclei, the 5-HT1A receptors are ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
59 GENERAL INTRODUCTION 8 Chapter 1
 

Summary:  contains five receptor subtypes, of which the 5-HT1A receptors are widely distributed throughout the brain... . In the raphe nuclei, the 5-HT1A receptors are somatodendritic, and act as autoreceptors to inhibit cell firing... of raphe serotonergic cells. Postsynaptic 5-HT1A ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
60 Drugs for relapse prevention of alcoholism: ten years of progress
 

Summary:  - pared with NR1­NR2A receptors [32]. Alcohol-preferring msP rats (Table 1) have enhanced brain levels... and nalmefene interfere with alcohol consumption through the blockade of opioid receptors [6]. A recent meta... , at least partly, by an attenu- ation of the mesolimbic response to alcohol-associated ...

  

Source: Durstewitz, Daniel - Research Group Computational Neuroscience, Central Institute of Mental Health,

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine


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61 References Abad VC, Guilleminault C (2005) Sleep and psychiatry. Dialogues Clin Neurosci 7:291-303.
 

Summary:  ) Opposite changes in adenosine A1 and A2A receptor mRNA in the rat following sleep deprivation. Neuroreport... :220-226. Blier P, Seletti B, Gilbert F, Young SN, Benkelfat C (2002) Serotonin 1A receptor activation... nucleus: possible role in desensitization of 5-hydroxytryptamine1A ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
62 Incentive learning takes place when dopaminergic neurons are activated, usually by rewards. As a
 

Summary:  , T Kimura, T Maeda, K Kannari, M Matsunaga and M Baba (2005) A serotonin 5-HT1A receptor agonist pre- vents... effects of drugs (e.g., dopamine receptor blockade) and the improvement in symptoms (e.g., decreases... blockade or by 6-hydroxydopamine lesions, but shows a test-to-test extinction-like decline. ...

  

Source: Beninger, Richard J. - Department of Psychology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
63 Creating a focused corpus of factual outcomes from biomedical experiments
 

Summary:  decrease retard is_a attenuate attenuate is_a activity inhibit number expression augment expression... promote prevent exacerbate attenuate decrease effect increase potentiate regulate attenuate increase... potentiate inhibit postoperative attenuate aggravate inhibitis_a prevent ...

  

Source: Stevens, Robert - School of Computer Science, University of Manchester

 

Collection: Computer Technologies and Information Sciences

 
64 Introduction Chapter 1 1 Introduction
 

Summary:  of the 5-HT7(a) receptor with other serotonin receptors. Amino acid similarity: identical or similar amino... terminals due to a the presence of a second intron (Figure 1.3)80,81,100,134,203,211 . The 5-HT7(a) receptor... and physiological roles for each of these isoforms. RT- PCR studies have identified the ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
65 Exp Brain Res (1986) 65: 182-188 EXp'erjmentaJ
 

Summary:  deprivation. Many substances have been reported to attenuate cortical plasticity, but unlike activity blockade... activity blockade prevents ocular dominance plasticity in the kitten visual cortex* H. O. Reiter!, D. M... primary visual cortex show that a reversible blockade of the discharge activities of ...

  

Source: Stryker, Michael - W.M. Keck Foundation Center & Department of Physiology, University of California at San Francisco

 

Collection: Biology and Medicine

 
66 P-Glycoprotein Function at the BloodBrain Barrier Imaged Using 11C-N-Desmethyl-
 

Summary:  underwent 12 PET scans of the brain, 5 at baseline and 7 after pharmacologic blockade of P-gp. A subset... -gp blockade affected peripheral distribution of 11C-dLop, we measured whole-body biodistribution in 4 mon... - keys at baseline and after P-gp blockade. Results: The con- centration of 11C-dLop in the brain was low

  

Source: Pike, Victor W. - Molecular Imaging Branch, National Institute of Mental Health

 

Collection: Biology and Medicine

 
67 P-Glycoprotein Function at the BloodBrain Barrier Imaged Using 11C-N-Desmethyl-
 

Summary:  underwent 12 PET scans of the brain, 5 at baseline and 7 after pharmacologic blockade of P-gp. A subset... -gp blockade affected peripheral distribution of 11C-dLop, we measured whole-body biodistribution in 4 mon... - keys at baseline and after P-gp blockade. Results: The con- centration of 11C-dLop in the brain was low

  

Source: Innis, Robert B. - Molecular Imaging Branch, National Institute of Mental Health

 

Collection: Biology and Medicine

 
68 Treatment with 8-OH-DPAT attenuates the weight loss associated with activity-based anorexia in female rats
 

Summary:  ;60:494­500. Shimizu N, Hori T, Ogino C, Kawanishi T, Hayashi Y. The 5-HT1A receptor agonist, 8-OH-DPAT, attenuates... ;112:55­63. Carey RJ, DePalma G, Damianopoulos E, Muller CP, Huston JP. The 5-HT1A receptor and behavioral... S, Oerther S, Ahlenius S. Additive hypothermic effects of ...

  

Source: Contreras, Robert J. - Department of Psychology, Florida State University

 

Collection: Biology and Medicine

 
69 STRESSOR SUSCEPTIBILITY IN LOW AND HIGH AGGRESSIVE MICE: EFFECTS OF TIME AND OF TYPE
 

Summary:  (5-HT1A) receptor was decreased. In contrast to LAL mice, markers of the HPA system in SAL mice... conditions (Veenema et al., 2003a). LAL mice had a lower hippocampal 5-HT1A receptor gene expression... RNA expression of MR, glucocorticoid receptor (GR), and 5-HT1A ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
70 5-HT1A Autoreceptor Levels Determine Vulnerability to Stress and Response
 

Summary:  et al., 2002). Furthermore, pharmacological blockade of 5-HT1A receptors in development... (5-HT1A) receptor gene in increased sus- ceptibility to depression and decreased treatment response... receptors. The serotonin-1A (5-HT1A) receptor is an ...

  

Source: Grangier, Philippe - Quantum Optics Group, Institut d'Optique, Orsay

 

Collection: Physics

 
71 SYNERGISTIC SEDATIVE EFFECTS OF NORADRENERGIC a1-AND b-RECEPTOR BLOCKADE ON FOREBRAIN ELECTROENCEPHALOGRAPHIC AND
 

Summary:  SYNERGISTIC SEDATIVE EFFECTS OF NORADRENERGIC a1- AND b-RECEPTOR BLOCKADE ON FOREBRAIN... and behavioral effects of a1-, b- and combined a1/b-receptor blockade in the unanesthetized rat. Rats were... activity was analysed using power spectrum analysis. The following were observed: (i) b-receptor blockade

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
72 doi:10.1152/ajpregu.00215.2010 300:R1468-R1475, 2011. First published 16 March 2011;Am J Physiol Regul Integr Comp Physiol
 

Summary:  . Pivotal role of AT1A receptors in the development of two-kidney, one-clip hypertension: study in AT1A... 88: 456­461, 1991. 29. Majid DSW, Navar LG. Blockade of distal nephron sodium transport attenuates... hypertension (25, 32). Previous studies demonstrated that renal blood flow ...

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
73 Neuromodulatory Role of Serotonin in the Ferret Thalamus JAMES E. MONCKTON AND DAVID A. MCCORMICK
 

Summary:  an increase in potassium conductance mediated through the 5-HT1A receptor. This conclusion is supported... in the lateral pulvinar. Pharmacological evidence supports the role of the 5-HT1A receptor in the 5-HT... in micropipette; Fig. 5C; n 17 pulvinar, 5 nonpulvinar), thus providing strong evidence for ...

  

Source: McCormick, David - Department of Neurobiology, Yale University

 

Collection: Biology and Medicine

 
74 The role of serotonin in clinical disorders The role of serotonin in clinical disorders
 

Summary:  neurotransmission through blockade of 5HT2A receptors and inhibition of serotonin uptake. The active metabolite, m... 1A receptor signal transduction. It has been shown that ACTH and corticosterone administration may... (Aston-Jones et al, 1991; Morgane et al, 1979). ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
75 CAFFEINE, COGNITIVE FUNCTIONING AND WHITE MATTER LESIONS IN THE ELDERLY: ESTABLISHING CAUSALITY FROM EPIDEMIOLOGICAL EVIDENCE
 

Summary:  benefit for persons with Alzheimer's disease (AD). Blockade of adenosine A2A receptors appears... , indicating that blockade of adenosine A2A receptors limits brain A levels [4, 5], we may assume high caffeine... -selective antagonism of adenosine receptors, ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
76 The role of central dopamine D3 receptors in drug addiction: a review of pharmacological evidence
 

Summary:  indicates that the 5- HT2A receptor antagonist M100,907 attenuates the ability of a priming injection... of the D2 site is also observed [20,114,250] as well as labeling of j [250,296] and 5-HT1A receptors [72... , personal communica- tion). The interaction with ...

  

Source: Brookhaven National Laboratory, Environmental Chemistry Division, Department of Applied Science

 

Collection: Environmental Sciences and Ecology

 
77 Myoclonus and Paroxysmal Dyskinesias
 

Summary:  . NAN-190, the high affinity 5-HT1A receptor antagonist did not block synchronous motor activity... high micromolar concentrations. These included the 5-HT1A receptor antagonist WAY-100635 (n=1, 11 µ... of glycine receptor blockade; he also highlighted the potential value of this model ...

  

Source: Hochman, Shawn - Department of Physiology, Emory University

 

Collection: Biology and Medicine

 
78 Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic
 

Summary:  to the perfusion of drugs. The effects of the 5-HT1A receptor agonist ipsapirone were evaluated by comparing... of 5-HT1A autoreceptors is unaltered in BDNF +/x mice We assessed presynaptic 5-HT1A receptor status... raphe serotonergic neurons in brainstem slices indicated that the 5-HT1A ...

  

Source: Andrews, Anne M. - Huck Institutes of the Life Sciences, Pennsylvania State University

 

Collection: Biology and Medicine

 
79 Current Topics in Medicinal Chemistry 2005, 5, 547-555 547 1568-0266/05 $50.00+.00 2005 Bentham Science Publishers Ltd.
 

Summary:  - is maintained at a high level and this causes a membrane depolarization when GABA-A receptors are activated due... in a reversal of GABA-A receptor mediated currents which now produce a net inflow of anions and an inward... activates GABA-A receptors on primary ...

  

Source: Price, Theodore - Department of Pharmacology, University of Arizona

 

Collection: Biology and Medicine

 
80 Augmentation of the Neurochemical and Behavioural Effects of SSRIs
 

Summary:  ). It has also been suggested that these reuptake receptors, as well as 5-HT1A, 5-HT1B and 5-HT2A receptors... . This suggests that, in contrast to observations in the median raphe nuclei, 5-HT1A receptors in the dorsal raphe... been shown that while the 5-HT1A ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology


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81 The concept of purinergic neurotransmission was pro-posed in 1972 (REF. 1), after it was shown that adenosine
 

Summary:  decreased in Huntington's disease87 and blockade of A2A receptors prevents electro- encephalogram (ee... in rodents, which is antagonised by caffeine. A2A receptors in the nucleus accumbens mediate this locomotor... and neurotrophin acting through TrkA ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
82 Serotonergic Modulation of Neurotransmission in the Rat Basolateral Amygdala
 

Summary:  A receptor agonist, ( ) 8- hydroxydipropylaminotetralin hydrobromide (8-OH-DPAT), or the 5-HT1B... ). Even within the amygdala regional differences exist. Hence 5-HT1A receptors are found predominantly... is the 5-HT1A receptor subtype (see Saxena 1995). However, the ...

  

Source: Rainnie, Donald "Tig" - Yerkes National Primate Research Center, Emory University

 

Collection: Biology and Medicine

 
83 Respiratory Physiology & Neurobiology 168 (2009) 133143 Contents lists available at ScienceDirect
 

Summary:  and temper- ature and that loss of medullary 5-HT1A receptors, as observed in SIDS, may attenuate protective... A receptors (Morin et al., 1990, 1991a,b; Di Pasquale et al., 1992; Onimaru et al., 1998; Manzke et... suggests that the 5-HT2A ...

  

Source: Wagner, Diane - Institute of Arctic Biology, Department of Biology and Wildlife, University of Alaska Fairbanks

 

Collection: Environmental Sciences and Ecology

 
84 Neurobiology of Disease Critical Involvement of cAMP/DARPP-32 and Extracellular
 

Summary:  ., 2000). Moreover, blockade of AMPA receptors results in a significant attenuation of LID (Konitsiotis et... for dyskinesia. Thus, LID is attenu- ated by genetic inactivation of DARPP-32 or by blockade of ERK signaling... and that genetic or pharmacolog- ical attenuation of ...

  

Source: Sandini, Giulio - Dipartimento di Informatica Sistemistica e Telematica, Università degli Studi di Genova

 

Collection: Engineering ; Computer Technologies and Information Sciences

 
85 Brain and Whole-Body Imaging in Rhesus Monkeys of 11C-NOP-1A, a Promising PET Radioligand for
 

Summary:  concentration of 11C-NOP-1A peaked at approxi- mately 2 min and decreased quickly thereafter (Fig. 2A). Receptor... , was 15% 6 2% (n 5 4 blood samples). PET Scans PET scans at baseline and after NOP-receptor blockade were... was acquired at about 98­102 min after injection. All images were corrected for ...

  

Source: Innis, Robert B. - Molecular Imaging Branch, National Institute of Mental Health

 

Collection: Biology and Medicine

 
86 The relevance of the serotonergic system in depression The relevance of the serotonergic system in
 

Summary:  for 5-HT3), the 5-HT1A receptor is a member of the 7 transmembrane G-protein coupled receptor (7-TM GPCR... decreasing their susceptibility to depolarise. Overall, the 5-HT1A receptor is regarded as an inhibitory... such as prefrontal cortex and hippocampus. 5-HT1B Similar to the 5-HT1A ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
87 General discussion 1. Neurobiological consequences of chronic partial sleep deprivation
 

Summary:  that chronic partial sleep deprivation gradually alters serotonin 1A receptor sensitivity in a direction... desensitization has been shown by two different functional read-outs of the serotonergic 1A receptor system... in response to an injection of the serotonin-1A ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
88 Clinical efficacy of antidepressants in depression Clinical efficacy of antidepressants in depression
 

Summary:  . There is growing evidence that postsynaptic 5-HT1A receptors are also involved in the control of serotonin release... been shown that at least the 5-HT1A receptors (presynaptically as well as postsynaptically) desensitize... 1998, Meanna et al. 1992). Augmentation with 5-HT1A ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
89 The contribution of the renin--angiotensin system (RAS) to the maintenance of mean arterial blood pressure (MABP)
 

Summary:  angiotensin converting enzyme (ACE) inhibition (n = 4), and by 25 ± 5 mmHg after ganglionic blockade (n = 4... of the two frequency ranges under the following conditions: (1) during ganglionic blockade (n = 7), (2... of the baroreceptor reflex had been suppressed by ganglionic blockade (Wagner et al. 1997). These oscillations ...

  

Source: Just, Armin - Physiologisches Institut I, Albert-Ludwigs-Universität Freiburg

 

Collection: Biology and Medicine

 
90 The Novel Antipsychotic Drug Lurasidone Enhances NMDA Receptor-Mediated Synaptic Responses
 

Summary:  and as a partial agonist at the 5-HT1A receptor (Ishibashi et al 2010). Our previous studies have found that a 5-HT... that selective agonists or antagonists for 5-HT1A or 5-HT2A receptors either reduce NMDAR-EPSC or have no effect... subtype 5-HT7A receptor. J Biol ...

  

Source: Yan, Zhen - Department of Physiology and Biophysics, State University of New York at Buffalo

 

Collection: Biology and Medicine

 
91 Altered serotonergic and corticotropin releasing hormone regulation of the hypothalamo-pituitary-adrenal stress system in
 

Summary:  is supported by our earlier studies showing that another 1A receptor-mediated response is also attenuated... by the serotonin-1A receptor, which has a more dominant role than other receptor subtypes (Dinan, 1996b). One... of our earlier studies has shown that the overall serotonin- ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
92 ATP signalling in epilepsy Ashwin Kumaria & Christos M. Tolias &
 

Summary:  effects [11, 12]. On the other hand, Zeraati et al. [13] elegantly showed that A2A receptors in the CA1... have been shown to underlie seizures, and conventional antiepileptic drugs have been shown to attenuate... [36, 37]. Calcium waves can be evoked by applying ATP, which acts on P2 receptors, the blockade

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
93 Blockade of paraventricular hypothalamic alpha adrenoceptors impairs the counterregulation to
 

Summary:  Chapter 5 Blockade of paraventricular hypothalamic alpha... noradrenaline in the hypothalamus Chapter 5 Blockade of paraventricular hypothalamic alphaadrenoceptors... responses were monitored. It was shown that blockade of the noradrenergic signal resulted

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
94 Genetic Inactivation of the Serotonin1A Receptor in Mice Results in Downregulation of Major GABAA Receptor Subunits, Reduction
 

Summary:  Genetic Inactivation of the Serotonin1A Receptor in Mice Results in Downregulation of Major GABAA... -HT1A) receptor knock-out mice display BZ-resistant anxiety. Consistent with this finding, binding... , initiated by a 5-HT1A receptor deficit, leading to abnor- ...

  

Source: Sibille, Etienne - Center for the Neural Basis of Cognition & Department of Psychiatry, University of Pittsburgh

 

Collection: Biology and Medicine

 
95 Mapping convulsants' binding to the GABA-A receptor chloride ionophore: A proposed model for channel binding sites
 

Summary:  Mapping convulsants' binding to the GABA-A receptor chloride ionophore: A proposed model... ionophore of GABA-A receptors, this model enables a better under- standing of complex architectonics... . Keywords: GABA-A receptors; Ionophore; Channel chemoconvulsants; ...

  

Source: Kalueff, Allan V. - Department of Pharmacology, Tulane University

 

Collection: Biology and Medicine

 
96 Stereoselectivity of 8-OH-DPAT toward the serotonin 5-HT1A receptor: Biochemical and molecular modeling study
 

Summary:  -isomer capable to evoke such effect in HP. Since 5-HT synthesis rate attenuation is related to 5-HT1A receptor... Stereoselectivity of 8-OH-DPAT toward the serotonin 5-HT1A receptor: Biochemical and molecular... February 2006 Accepted 10 May 2006 Keywords: 5-HT1A ...

  

Source: Skolnick, Jeff - Center for the Study of Systems Biology, Georgia Institute of Technology

 

Collection: Chemistry ; Biology and Medicine

 
97 GENERAL INTRODUCTION chapter 1_________________________________________________________________________
 

Summary:  intestinal mucosa of the rat. Also, the CCK-A receptor ­ which is the receptor type CCK acts on to induce... animal lacks CCK-A receptors and is an animal model of type 2 diabetes, characterized by abdominal... at an important role of the CCK-A receptor in the ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
98 Physiological consequences of selective suppression of synaptic transmission in developing cerebral cortical networks in vitro: Differential effects on intrinsically
 

Summary:  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1572 2.1. Partial excitatory amino acid receptor blockade... (within several hours) towards baseline levels despite sustained blockade of excitatory synaptic... blockade appears to protect neuronal ...

  

Source: van Pelt, Jaap - Center for Neurogenomics and Cognitive Research & Department of Experimental Neurophysiology, Vrije Universiteit Amsterdam

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine

 
99 Beta-Adrenergic and Atrial Natriuretic Peptide Interactions on Human Cardiovascular and Metabolic Regulation
 

Summary:  study, systemic beta-adrenergic receptor blockade did not attenuate the response. To further address... explain the attenuation in ANP induced lipid oxidation during beta-adrenoreceptor blockade. It is possible... , lactate, pyruvate. Results: ANP increased heart rate dose dependently. Beta-adrenergic ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
100 8 Am J Psychiatry 163:1, January 2006 http://ajp.psychiatryonline.org
 

Summary:  to pharmacological blockade of the serotonin transporter, suggesting that the exact mechanisms leading to disease... . For example, blockade of serotonin trans- "The liability for depression in adulthood may result from altered... through either reduced serotonin transporter expression or pharmacological blockade, respectively

  

Source: Sibille, Etienne - Center for the Neural Basis of Cognition & Department of Psychiatry, University of Pittsburgh

 

Collection: Biology and Medicine


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