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Sample search results for: abc transporter-mediated multidrug

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1 [1] Nikaido,H. (1994) Prevention of drug access to bacterial targets: permeability barriers and active efflux. Science, 264, 382-388.
 

Summary:  ,T., Mizushima,T., & Tsuchiya,T. (2003) Molecular cloning and characterization of an ABC multidrug efflux pump... ,M., Poolman,B., Driessen,A.J.M., & Konings,W.N. (1996) Energetics and mechanism of drug transport mediated... ,H., Oussenko,I., Kok,J., Poolman,B., Driessen,A.J., & Konings,W.N. (1996) ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
2 List of publications 1. Poelarends, G.J., Mazurkiewicz, P., Putman, M., Cool, R.H., van Veen,
 

Summary:  .W., and Konings, W.N. (2000). An ABC-type multidrug transporter of Lactococcus lactis possesses an exceptionally... a heterodimeric ABC- type multidrug transporter. Accepted to J. Biol. Chem. 7. Mazurkiewicz, P., Driessen, A... .N., and Poelarends, G.J. (2002). Acidic residues in the lactococcal ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
3 Multidrug and peptide export in Lactococcus lactis
 

Summary:  Multidrug and peptide export in Lactococcus lactis Bart van den Berg van Saparoea 2009 #12;The work... ;RIJKSUNIVERSITEIT GRONINGEN Multidrug and peptide export in Lactococcus lactis Proefschrift ter verkrijging van het... in Lactococcus lactis 7 Chapter 2 Heterologously expressed bacterial and human multidrug resistance proteins

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
4 Introduction General introduction
 

Summary:  -type multidrug transporter Secondary multidrug transporters These transporters mediate the extrusion of toxic... -energy by ATP hydrolysis. Figure 4. Schematic representation of (1) secondary multidrug transporter and (2) ABC... -type multidrug ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
5 Genome Biology 2004, 5:R15 commentreviewsreportsdepositedresearchrefereedresearchinteractionsinformation
 

Summary:  has not been typical of strongly conserved gene families, and while we might have inferred that ABC-transporter-mediated... with multidrug resistance (MDR). Decottignies and Goffeau [6] catalogued the entire ABC transporter family... commentreviewsreportsdepositedresearchrefereedresearchinteractionsinformation Open ...

  

Source: Baillie, David - Department of Molecular Biology and Biochemistry, Simon Fraser University

 

Collection: Biology and Medicine

 
6 Function of prokaryotic and eukaryotic ABC proteins in lipid transport Antje Pohla,b
 

Summary:  . Since then, there have been many indications for lipid transport mediated by ABC proteins in cellular... to the occurrence of multidrug resistant strains. Specific attention will be given here to ABC proteins found... of Leishmania [163]. LtrABC1.1 expres- sion ...

  

Source: Institut de Biologie Physico-Chimique CNRS, Physico-Chimie Moléculaire des Membranes Biologiques

 

Collection: Chemistry ; Biology and Medicine

 
7 General introduction General introduction
 

Summary:  consisting of a TMD fused to the NBD. The secondary multidrug transporter mediate drugs extrusion... to be resistant to several chemically unrelated drugs is termed the multidrug resistance (MDR) phenomenon... -emergence of the multidrug resistant tuberculosis bacterial strain (MDR-TB) ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
8 Activation of multidrug efflux transporter activity at fertilization in sea urchin embryos (Strongylocentrotus purpuratus)
 

Summary:  functional and molecular evidence for acquisition of multidrug transporter-mediated efflux activity... accumu- lates to a lesser extent. A specific test for multidrug transporter-mediated efflux activity... . These multidrug (mdr) efflux transporters are members of the ATP Binding ...

  

Source: 

 

Collection: Environmental Sciences and Ecology

 
9 Oligomerization of the Human ABC Transporter ABCG2: Evaluation of the Native Protein and Chimeric Dimers
 

Summary:  of the ATP binding cassette (ABC) transporter superfamily, is overexpressed in numerous multidrug... transporter-mediated efflux. Cellular fluorescence was measured using a FACSCalibur flow cytometer (Becton... in drug-free media to allow for transporter-mediated efflux. Cellular drug accumulation was ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
10 1. Teuber, M. (1995) The genus Lactococcus, in The Lactic Acid Bacteria (Wood, B. J. B. and Holzapfel, W. H., Eds.) 1 ed., pp 173-234, Blackie Academic and Professional,
 

Summary:  -deficient Streptococcus pneumoniae strain panel to identify ABC-class multidrug transporters involved in intrinsic... , H. W. (2003) An ABC transporter with a secondary-active multidrug translocator domain, Nature 426... ) The transmembrane domains of the ABC multidrug ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
11 Drug efflux mechanism by a secondary transporter LmrP
 

Summary:  : What do the proton motive force-driven multidrug resistance transporters have in common? 9 Chapter 2... Acidic residues in the lactococcal multidrug efflux pump LmrP play critical roles in transport... of lipophilic cationic compounds 31 Chapter 3 Facilitated drug influx by an energy-uncoupled secondary multidrug

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
12 Regulation of multidrug resistance in Lactococcus Herfita Agustiandari
 

Summary:  consisting of a TMD fused to the NBD. The secondary multidrug transporter mediate drugs extrusion... ., Driessen, A. J. M. 2008. The ABC-type multidrug resistance transporter LmrCD is responsible... R is a transcriptional repressor of expression of the multidrug ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
13 Reference list Ainsa, J. A., Blokpoel, M. C., Otal, I., Young, D. B., De Smet, K. A. and Martin, C. (1998). Molecular cloning and
 

Summary:  . (1996a). Energetics and mechanism of drug transport mediated by the lactococcal multidrug transporter... , a putative multidrug efflux pump present in Mycobacterium fortuitum and Mycobacterium tuberculosis. J... fluxes of rhodamine 123 in multidrug-resistant cells: evidence against ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
14 10.1110/ps.051998406Access the most recent version at doi: 2006 15: 1597-1607Protein Sci.
 

Summary:  transporter-mediated multidrug efflux. FEBS Lett. 580: 1042­1048. Riordan, J.R. 1993. The cystic fibrosis... , G. 2003. Structure of MsbA from Vibrio cholera: A multidrug resistance ABC transporter homolog... . coli: A homolog of the multidrug resistance ATP binding cassette ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
15 LmrCD is a major MDR transporter in Lactococcus lactis
 

Summary:  aureus or its homolog PmrA from S. pneumoniae. Although putative ABC-type multidrug resistance... a distinct multidrug sensitive phenotype upon deletion of a bacterial ABC-type MDR system. Phenotypic effects... and characterization of an ABC multidrug efflux pump, ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
16 The role of multixenobiotic transporters in predatory marine molluscs as counter-defense mechanisms against dietary allelochemicals
 

Summary:  and molecular evidence for multixenobiotic transporter-mediated efflux activity and expression in the generalist... -gp and multidrug resistance-associated protein (MRP) families of ABC transporters in T. hamnerorum. In addition, we... Available online 21 May 2010 Keywords: ABC transporter Allelochemical ...

  

Source: Sotka, Erik - Grice Marine Laboratory, College of Charleston

 

Collection: Environmental Sciences and Ecology

 
17 Relationships between MDR proteins, bacteriocin production and proteolysis in Lactococcus lactis
 

Summary:  -type multidrug transporter Secondary multidrug transporters These transporters mediate the extrusion of toxic... -energy by ATP hydrolysis. Figure 4. Schematic representation of (1) secondary multidrug transporter and (2) ABC... -type multidrug ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
18 List of Abbreviations Acknowledgments
 

Summary:  ;Appendix 186 List of Abbreviations 1,25(OH)2D3 1,25-dihydroxyvitamin D3 ABC ATP-binding cassette ASBT... ;List of Abbreviations 187 MDR (P-gp) multidrug resistance protein or P-glycoprotein MRP multidrug

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
19 doi:10.1006/scdb.2001.0250, available online at http://www.idealibrary.com on seminars in CELL & DEVELOPMENTAL BIOLOGY, Vol. 0, 2001: pp. 110
 

Summary:  human cancers. Key words: ABC superfamily / chemotherapy / P-glyco- protein / multidrug resistance... of mammalian P-glycoproteins involved in multidrug resistance Christine A. Hrycyna A variety of human cancers... as the multidrug resistance transporter or P-glycoprotein. P-glycoprotein is a member of the ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
20 Aquatic Toxicology 61 (2002) 127140 www.elsevier.com/locate/aquatox Tolerance to biodegraded crude oil in marine invertebrate
 

Summary:  inhibitor of MXR transport-mediated dye efflux in Urechis larvae. These results suggest that MXR may... as multidrug resistance, MDR). This mechanism is primarily mediated by ATP-dependent, efflux pumps that extrude... . This phenomenon is similar to multidrug resistance (MDR) in mammalian cells, which is associated

  

Source: 

 

Collection: Environmental Sciences and Ecology


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21 Reduced intracellular accumulation of calcein by overexpression of fluorescent protein fusions of the multidrug transporter Sp-ABCB1a, in sea urchin (Strongylocentrotus purpuratus) embryos.
 

Summary:  of the multidrug transporter Sp-ABCB1a, in sea urchin (Strongylocentrotus purpuratus) embryos. Amro Hamdoun1 1... Scripps Institution of Oceanography, La Jolla, CA 92037 hamdoun@ucsd.edu Multidrug efflux transporters... eggs results in dramatic up-regulation of outwardly-directed multidrug transport activity(5) . One

  

Source: 

 

Collection: Environmental Sciences and Ecology

 
22 N d'ordre : 270-2007 Anne 2007 prsente devant
 

Summary:  ........................................................ 17 2. Les transporteurs ABC chez l... ............................................................................................. 36 3.2. Evolution de la branche « C » de la superfamille ABC... .10.2. Fonctionnement coopératif des NBD des protéines ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
23 What do the proton motive force-driven multidrug resistance transporters have in common?
 

Summary:  Chapter 1 What do the proton motive force-driven multidrug resistance transporters have in common... sequencing projects in recent years has demonstrated that multidrug resistance (MDR) transporters are widely... of multidrug recognition and the transport mechanisms will allow a more rational design of new drugs which

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
24 ABC transporters ABC transporter architecture and regulatory roles of
 

Summary:  (CFTR/ABCC7), an ABC-type chloride channel, and multidrug- resistance conferred to tumor cells by P... , some ABC systems, including the sulfonylurea receptors SUR1 and SUR2, and the multidrug... ABC transporters 9 Chapter 2 ABC transporter architecture and regulatory ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
25 UNIVERSIT PARIS XI FACULT DE PHARMACIE DE CHTENAY-MALABRY
 

Summary:  transporteurs ABC 63 CHAPITRE 3 : Les transporteurs ABC 64 1- Généralités et structures des transporteurs ABC 64... 2-5- Régulation du gène mdr1 73 3- La sous-famille MRP (Multidrug Resistance associated Proteins) 75... - Transporteurs ABC et VIH 81 5-1- Effet de l'infection par le ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
26 Annu. Rev. Pharmacol. Toxicol. 1999. 39:36198 BIOCHEMICAL, CELLULAR,
 

Summary:  OF THE MULTIDRUG TRANSPORTER1 Suresh V. Ambudkar, Saibal Dey, Christine A. Hrycyna, Muralidhara Ramachandra,+,2 Ira... .ramachandra@canjii.com; pasta@helix.nih.gov; and mgottesman@nih.gov KEY WORDS: multidrug resistance, P-glycoprotein, drug... accumulated indicating that the multidrug transporter or P-glycoprotein plays a role ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
27 Hop Resistance in the Beer Spoilage Bacterium Lactobacillus brevis Is Mediated by the ATP-Binding
 

Summary:  HorA protein identified HorA as a new member of the ABC family of multidrug transporters. #12;CHAPTER... bacterial multidrug resistance proteins, LmrA is an ATP-binding cassette (ABC) transporter (Higgins, 1992... of the ABC multidrug transporter LmrA in L. lactis ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
28 Introduction to multidrug transporters, cellular resistance and lantibiotic production in Lactococcus lactis
 

Summary:  7 Chapter 1 Introduction to multidrug transporters, cellular resistance and lantibiotic production... in Lactococcus lactis H. Bart van den Berg van Saparoea and Arnold J.M. Driessen Summary Multidrug resistance... on drug resistance, while LmrCD has been shown to be a major determinant in the multidrug resistance

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
29 368 VOLUME 86 NUMBER 4 | OCTOBER 2009 | www.nature.com/cpt STATE ART nature publishing group
 

Summary:  to image the function of the ABC trans- porter ABCC1 (multidrug-resistance protein, or MRP1) in wild... traverse the well by passive diffu- sion or transporter-mediated processes.7,10 A compound is iden- tified... Transporters belonging to the adenosine triphosphate (ATP)- binding cassette (ABC) superfamily ...

  

Source: Innis, Robert B. - Molecular Imaging Branch, National Institute of Mental Health

 

Collection: Biology and Medicine

 
30 Chemistry and Physics of Lipids 141 (2006) 119132 Proteins involved in lipid translocation in eukaryotic cells
 

Summary:  of the multidrug resistance proteins ABC transporters in eukaryotes (Chang and Roth, 2001). The three- dimensional... .B., 2001. Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC... .B., Goffeau, A., 1998. ATPase and multidrug transport ...

  

Source: Institut de Biologie Physico-Chimique CNRS, Physico-Chimie Moléculaire des Membranes Biologiques

 

Collection: Chemistry ; Biology and Medicine

 
31 Novel mechanism of bacteriocin secretion and immunity involving lactococcal MDR proteins
 

Summary:  lactococcal multidrug transporters mediate bacteriocin resistance by extruding them from the cytoplasmic... within a gene cluster specifying LmrB, an ATP-binding-cassette-type multidrug resistance transporter... the two polypeptides from the cytoplasmic membrane. This is the first report in which a ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
32 EFFLUX TRANSPORTERS: Newly Appreciated
 

Summary:  transporter proteins belonging to the adenosine triphosphate (ATP)-bindingcassette(ABC... -binding region referred to as the ABC cassette © 2008 American Chemical Society rhondasaunders 3914 Environm... EntAl SCiEnCE & tEChnology / JunE 1, 2008 #12;(hence, ABC transporters), and are present in all or- ganisms

  

Source: 

 

Collection: Environmental Sciences and Ecology

 
33 Acidic residues in the lactococcal multidrug efflux pump LmrP play critical roles in transport of lipophilic cationic
 

Summary:  Chapter 2 Acidic residues in the lactococcal multidrug efflux pump LmrP play critical roles... SUMMARY The proton motive force-driven efflux pump LmrP confers multidrug resistance on Lactococcus lactis... -called multidrug resistance transporters (MDRs), can be divided in two major classes: (i) secondary MDRs

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
34 Applied Mathematics Letters 24 (2011) 12511256 Contents lists available at ScienceDirect
 

Summary:  ]. The enhancement of ABC transporter expression in Abbreviations: MDR, Multidrug resistance; ABC transporter, ATP... to trigger the induction of ATP-Binding Cassette (ABC) transporters, responsible for the efflux of the drug... of CPT11-induced overexpression of ABC transporters. We then ...

  

Source: Clairambault, Jean - Biologie, Analyse Numérique, Géophysique Team, INRIA Paris-Rocquencourt

 

Collection: Biology and Medicine

 
35 Abstract. The typically distinct phospholipid composi-tion of the two leaflets of a membrane bilayer is generated
 

Summary:  ]. A major unresolved question concerns the precise nature of lipid transport mediated by the various ABC... transporters, mediate the net transfer of specific phospholipids to one leaflet of a membrane and are involved... assembly, membrane asymmetry, lipid flip-flop, N-glycosylation, ...

  

Source: Menon, Anant K. - Menon Lab, Weill Medical College, Cornell University

 

Collection: Biology and Medicine

 
36 Data-Based Mathematical Modeling of Vectorial Transport across Double-Transfected Polarized CellsS
 

Summary:  protein 2 (MRP2) (Bu¨chler et al., 1996). Such double-transfected cells exhibit transporter-mediated... mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells... ¨nig et al., 2000), and the human apical conju- gate export pump ABCC2, also known as ...

  

Source: Timmer, Jens - Freiburger Zentrum für Datenanalyse und Modellbildung & Physikalisches Institut, Albert-Ludwigs-Universität Freiburg

 

Collection: Physics

 
37 Data-Based Mathematical Modeling of Vectorial Transport across Double-Transfected Polarized CellsS
 

Summary:  protein 2 (MRP2) (Bu¨chler et al., 1996). Such double-transfected cells exhibit transporter-mediated... , Leier I, and Keppler D (1999) Drug resistance and ATP-dependent conjugate transport mediated... ¨nig et al., 2000), and the human apical conju- gate export pump ABCC2, also known as multidrug resistance

  

Source: Timmer, Jens - Freiburger Zentrum für Datenanalyse und Modellbildung & Physikalisches Institut, Albert-Ludwigs-Universität Freiburg

 

Collection: Physics

 
38 Functional hot spots in human ATP-binding cassette transporter
 

Summary:  review implicated 12 ABC transporters from four families in in vitro multidrug resistance in tissue... , and the TMD of the structure of the Staphylococcus aureus multidrug ABC transporter Sav1866 in light blue... the catalytic cycle of the multidrug ABC transporter ...

  

Source: Sali, Andrej - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine ; Biotechnology

 
39 Structure of the transcriptional regulator LmrR and its mechanism of multi-drug recognition
 

Summary:  R-related transcriptional repressor that regulates the production of LmrCD, a major multidrug ABC transporter in Lactococcus... of the heterodimeric ABC transporter LmrCD, which is a major multidrug transporter in Lactococcus lactis (22... structure of a transcription factor regulating the expression of a ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
40 ATP-binding cassette protein E is involved in gene transcription and translation in Caenorhabditis elegans
 

Summary:  Received 5 August 2004 Available online 27 August 2004 Abstract ATP-binding cassette protein E (ABCE) gene... presence and high degree of conservation of ABCEs, however, RNase L is present only in mammals. This indi... - cates that ABCEs may function not only as RNase L inhibitors, but also may have other functions

  

Source: Baillie, David - Department of Molecular Biology and Biochemistry, Simon Fraser University

 

Collection: Biology and Medicine


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41 pour obtenir le titre de DOCTEUR de l'ECOLE POLYTECHNIQUE
 

Summary:  détoxication de la levure par les transporteurs ABC : 1 - étude biochimique de Yor1p 2 - rôle des thiols dans... ;Résumé 1 Les transporteurs ABC forment une vaste famille de protéines présentes dans tous les organismes... membranes biologiques des substances très variées. Plusieurs protéines ABC sont importantes pour la ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
42 LmrR is a transcriptional repressor of the expression of the Multidrug ABC transporter LmrCD in
 

Summary:  Chapter LmrR is a transcriptional repressor of the expression of the Multidrug ABC transporter Lmr... in Lactococcus lactis 62 SUMMARY LmrCD is an ABC-type multidrug transporter of Lactococcus lactis. LmrR encodes... , and A. J. Driessen. 2007. Distribution and physiology of ABC-type ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
43 Distinct mechanisms of LmrR mediated gene regulation of multidrug resistance
 

Summary:  ,J., Agustiandari,H., Kuipers,O.P., and Driessen,A.J.M. 2008. The ABC-type multidrug resistance transporter Lmr... Chapter Distinct mechanisms of LmrR mediated gene regulation of multidrug resistance in Lactococcus... Submitted #12;Multidrug resistance in Lactococcus lactis 76 SUMMARY ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
44 AnmtRev, Genct.1995, 29:607-49 Copyright1995by AnnualReviewsInc. All rights reserved
 

Summary:  ATP-dependent plasmamembranetransport system,knownas P-glyeoprotein,or the multidrug transporter... ................... 608 Identification and Characterization of the Multidrug Transporter ............... 609 The... GENETHERAPYUSINGMDRlAS A SELECTABLEMARKER................ 635 INTRODUCTION: MULTIDRUG RESISTANCE IN CANCER ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
45 Summary and concluding remarks Summary and concluding remarks
 

Summary:  for the intrinsic multidrug resistance in L. lactis. These are ABC half-transporter that heterodimerize to form... . The transmembrane domains of the ABC multidrug transporter LmrA form a cytoplasmic exposed, aqueous chamber within... Chapter Summary and concluding remarks #12;Summary and concluding remarks ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
46 General Introduction Chapter 1: General Introduction
 

Summary:  Transport mediated by secondary transporters can be divided into three major categories (Fig. 2) [163... . lactis is an ABC transporter responsible for multidrug resistance in this Gram-positive bacterium [218... -dependent primary transporters 21 4.1: The ABC superfamily portrait 21 4.2: ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
47 PROTEIN INTERACTIONS AND DISEASE PHENOTYPES IN THE ABC TRANSPORTER SUPERFAMILY
 

Summary:  selected to experimentally probe domain interactions in the human multidrug ABC transporter P-gp. We... PROTEIN INTERACTIONS AND DISEASE PHENOTYPES IN THE ABC TRANSPORTER SUPERFAMILY LIBUSHA KELLY1... Francisco, CA 94158, USA. ABC transporter proteins couple the energy of ATP binding and hydrolysis

  

Source: Sali, Andrej - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine ; Biotechnology

 
48 Bibliography Abrahams, J. and Leslie, A. (1996). Methods used in the structure determination of
 

Summary:  ., Romantsov, T., and Wood, J. M. (2008). Roles of K+, H+, H2O, and DeltaPsi in solute transport mediated... of a bacterial multidrug ABC transporter. Nature, 443, 180-5. Detmers, F., Lanfermeijer, F., Abele, R., Jack, R... , 1097-105. Biemans-Oldehinkel, E., Doeven, M. K., and Poolman, B. (2006). ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
49 Introduction EG van de Kerkhof
 

Summary:  Sci 54: 52-9 [47] Tsuji A. (2006) Impact of transporter-mediated drug absorption, distribution... and in vivo. Pharmacol Toxicol 90: 5-13 [49] Tsuji A. (2002) Transporter-mediated Drug Interactions. Drug... -binding cassette (ABC) transporter family by the Human Genome Organization (HUGO) Gene Nomenclature (SLC1-45: http

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
50 Copyright 2007 by the Genetics Society of America DOI: 10.1534/genetics.106.066720
 

Summary:  resistance. The PGP1 protein is a broad- spectrum multidrug efflux pump with the common ABC protein structure... Accepted for publication December 24, 2006 ABSTRACT ABC transporters constitute one of the largest gene... previously demonstrated that the Caenorhabditis elegans ABC family shows poor one-to-one ...

  

Source: Baillie, David - Department of Molecular Biology and Biochemistry, Simon Fraser University

 

Collection: Biology and Medicine

 
51 Energetics of wild-type and mutant multidrug resistance secondary transporter LmrP of Lactococcus lactis
 

Summary:  conditions, ethidium transport mediated by the mutant LmrPs D142C and E327C is -independent. This strongly... for Hoechst 33342 transport mediated by WT LmrP. In the mutants not only the number of protons transported... Chapter 4 Energetics of wild-type and mutant multidrug resistance ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
52 Summary and concluding remarks Introduction
 

Summary:  . coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters. Science 293, 1793... -1800. Chang, G. (2003) Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog... (ABC) transporters MsbA, a lipid efflux system that was crystallized ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
53 PharmGKB Submission Update: IV. PMT Submissions of Genetic Variations in ATP-
 

Summary:  IDs. Pharmacogenetic Significance: Genetic variation in the ATP-binding cassette (ABC) family... . Pharmacological Significance: ABC transporters are expressed in the basolateral (blood-facing) or api- cal (lumen... of ABC transporters in capillary endothelial cells of the blood-brain, blood-placenta, blood

  

Source: Sali, Andrej - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine ; Biotechnology

 
54 Multidrug Efflux Transporters Limit Accumulation of Inorganic, but Not
 

Summary:  typesofATP-BindingCassette(ABC)effluxtransporters(7-9), the ABCB/p-glycoprotein (P-gp) and the ABCC/multidrug... Multidrug Efflux Transporters Limit Accumulation of Inorganic, but Not Organic, Mercury in Sea... we examined the role of multidrug efflux transport in the differential accumulation of inorganic ...

  

Source: 

 

Collection: Environmental Sciences and Ecology

 
55 Structure and Dynamics of Large Biological Molecules: ATP-Binding Cassette (ABC) Transporters
 

Summary:  -glycoprotein) contribute to multidrug resistance of cancer cells, and ABC proteins are also associated with cystic fibrosis... . Dawson and K. P. Locher, Structure of a bacterial multidrug ABC transporter, Nature 443, 180-185, 2006. 6... , Structure of the multidrug ...

  

Source: Jones, R. O.- Institut für Festkörperforschung, Forschungszentrum Jülich

 

Collection: Materials Science

 
56 Introduction: Scope of the Thesis Ansar A. Khan
 

Summary:  of the solute carrier family (SLC) and the ATP-binding cassette (ABC) protein family, according... ), multidrug resistance associated protein (MRP)2 and multidrug resistance protein (Pgp; MDR) (38) also exhibit... ). They are detoxified by various phase I and phase II enzymes and further excreted by several ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
57 European Journal of Pharmaceutical Sciences 37 (2009) 106114 Contents lists available at ScienceDirect
 

Summary:  ­Menten-type, in cases of transport mediated by both intracellular and extracellular binding. The corresponding expres... . The results were applied to an absorption experiment with multidrug transporter-affected antibiotic CNV97100... asymptotic quantities of the diluted substance in each compartment. These and the constants ...

  

Source: Toral, Raúl - Mediterranean Institute for Advanced Studies & Departament de Física, Universitat de les Illes Balears

 

Collection: Materials Science ; Physics

 
58 A survey of integral a-helical membrane proteins Libusha Kelly Ursula Pieper Narayanan Eswar
 

Summary:  domains of the human ABC transporter superfamily, (2) to identify the multidrug resistance-associated mem... Membrane proteins Á Superfamily analysis Á Multidrug resistance Á ABC transporters Á Target selection... of the clinically important human ABC transporter superfamily. Second, ...

  

Source: Sali, Andrej - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine ; Biotechnology

 
59 Expression Analysis of ABC Transporters Reveals Differential Functions of Tandemly Duplicated Genes in
 

Summary:  Expression Analysis of ABC Transporters Reveals Differential Functions of Tandemly Duplicated Genes... , BC Canada V5Z 1L6 We have previously identified 60 predicted ABC transporter genes... these putative ABC genes work in worms, we generated promoter­fluorescent protein fusions for the entire family

  

Source: Baillie, David - Department of Molecular Biology and Biochemistry, Simon Fraser University

 

Collection: Biology and Medicine

 
60 Multidrug and peptide export in Lactococcus lactis
 

Summary:  Multidrug and peptide export in Lactococcus lactis Bart van den Berg van Saparoea 2009 #12;The work... ;RIJKSUNIVERSITEIT GRONINGEN Multidrug and peptide export in Lactococcus lactis Proefschrift ter verkrijging van het... in Lactococcus lactis 7 Chapter 2 Heterologously expressed bacterial and human multidrug resistance proteins

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology


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61 A Plasmid pRH45 of Lactobacillus brevis Confers Hop Resistance
 

Summary:  % identical to LmrA, a lactococcal ATP-binding cassette (ABC) multidrug transporter. Lb. brevis ABBC45C... that pRH45 confers hop resistance in Lb. brevis ABBC45 by excreting hop compounds by the multidrug ABC... multidrug transporter MDR1 (Chen et al., 1986). LmrA has been identified as ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
62 LIST OF AWARD RECIPIENTS UB2020 RESEARCH AND DEVELOPMENT ACTIVITIES FUND (IRDF)
 

Summary:  Regulation of ABC Membrane Transporters" Corresponding Investigator Aiming Yu Pharmaceutical Sciences School... resistance in cancer cells is one of the major obstacles for cancer therapy. Multidrug- resistance may... (BCRP) and multidrug-resistance protein 1 (MRP1) that are over- expressed in cancer cells and pump out

  

Source: Krovi, Venkat - Department of Mechanical and Aerospace Engineering, State University of New York at Buffalo

 

Collection: Engineering

 
63 Conjugating Berberine to a Multidrug Resistance Pump Inhibitor Creates an
 

Summary:  Conjugating Berberine to a Multidrug Resistance Pump Inhibitor Creates an Effective Antimicrobial... 02114 ABSTRACT In bacteria, multidrug-resistance pumps (MDRs) confer resistance to chemically unrelated... of the pathogen. E fflux by multidrug-resistance pumps (MDRs) is a universal mechanism by which microorganisms

  

Source: Ausubel, Frederick M. - Department of Genetics, Harvard University

 

Collection: Biology and Medicine

 
64 Hormone Transport Ian D. Kerr, David J. Carrier and Jamie Twycross
 

Summary:  , Martinoia E, Lee Y (2010) PDR-type ABC transporter mediates cellular uptake of the phytohormone abscisic... transport. Simply, we would remind the reader that the ATP-binding cassette (ABC) transporter COMATOSE [At... ...

  

Source: Twycross, Jamie - School of Computer Science, University of Nottingham

 

Collection: Computer Technologies and Information Sciences

 
65 Differential Sensitivities of the Human ATP-Binding Cassette Transporters ABCG2 and P-Glycoprotein to Cyclosporin A
 

Summary:  ABSTRACT Several ATP-binding cassette (ABC) transporters can confer multidrug resistance to cancer cells... -glycoprotein (P-gp) are two ABC transporters that, when overexpressed, are capable of extruding a variety... of structurally unrelated, commonly used chemo- therapeutic drugs, a phenomenon called ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
66 N-desmethyl-Loperamide Is Selective for P-Glycoprotein among Three ATP-Binding Cassette Transporters at the
 

Summary:  -brain barrier, the three most prevalent ABC transporters are P-glycoprotein (P-gp) (encoded by ABCB1), multidrug... -binding cassette efflux transporters at the blood-brain barrier are P-glycoprotein (P-gp), multidrug resistance... -gp. Efflux transporters of the ATP-binding cassette (ABC) family block the ...

  

Source: Innis, Robert B. - Molecular Imaging Branch, National Institute of Mental Health

 

Collection: Biology and Medicine

 
67 N-desmethyl-Loperamide Is Selective for P-Glycoprotein among Three ATP-Binding Cassette Transporters at the
 

Summary:  -brain barrier, the three most prevalent ABC transporters are P-glycoprotein (P-gp) (encoded by ABCB1), multidrug... -binding cassette efflux transporters at the blood-brain barrier are P-glycoprotein (P-gp), multidrug resistance... -gp. Efflux transporters of the ATP-binding cassette (ABC) family block the ...

  

Source: Pike, Victor W. - Molecular Imaging Branch, National Institute of Mental Health

 

Collection: Biology and Medicine

 
68 Candida Drug Resistance Protein 1, a Major Multidrug ATP Binding Cassette Transporter of Candida albicans, Translocates Fluorescent Phospholipids in a
 

Summary:  . Overexpression of the multidrug transporter Cdr1p (Can- dida drug resistance protein 1), a member of the ABC1... : Characterization of CDR2, a new multidrug ABC transporter gene, Microbiology 143, 405-416. 6. White, T. C. (1997... ., and Goffeau, A. (1998) ATPase and multidrug transport ...

  

Source: Menon, Anant K. - Menon Lab, Weill Medical College, Cornell University

 

Collection: Biology and Medicine

 
69 LIST OF PUBLICATONS Sakamoto, K. (1997) Detection of the genus Pectinatus. Japanese Patent Application JP09-
 

Summary:  ., Putman, M., Sakamoto, K., and Konings, W. N. (1999) Multidrug resistance in lactic acid bacteria... ., Margolles, A., Sakamoto, K., and Konings, W. N. (1999) Structure-function analysis of multidrug transporters... ., Sakamoto, K., and Konings, W. N. (2000) Molecular pharmacological characterization of two multidrug

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
70 4104-8--Templeton--Ch21--R1--07-24-03 16:17:03--Selectable Markers for Gene Therapy2
 

Summary:  dependent transporters (ABC transporters), including the 32 human multidrug resistance gene MDR1 (ABC B1) (3... ,5,6), 33 MRP1 (ABC C1), the multidrug resistance-associated protein 34 (7) and other MRP family members (8... ), and MXR (ABC G2) 35 (9). MDR1 encodes the ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
71 A genomic survey of the distribution of ABC-transporters in the hyperthermophilic archaeal Pyrococcus species
 

Summary:  Chapter 5 1 A genomic survey of the distribution of ABC-transporters in the hyperthermophilic... of ABC-transport systems. Of the seventeen to nineteen ABC-transporters present per species, eight... , phosphoenolpyruvate (PEP)- dependent phosphotransferase systems (PTS), and ATP-binding cassette (ABC-) ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
72 Bivalent Probes of the Human Multidrug Transporter P-Glycoprotein Marcos M. Pires, Christine A. Hrycyna,* and Jean Chmielewski*
 

Summary:  Bivalent Probes of the Human Multidrug Transporter P-Glycoprotein Marcos M. Pires, Christine A... library of bivalent agents was designed to probe the substrate binding sites of the human multidrug... the over- expression of a plasma membrane polypeptide known as the multidrug transporter or P

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
73 Functional Analysis of the Gene Cluster Involved in Circularin A, a Bacteriocin Produced by Clostridium
 

Summary:  . Tokuda. 2000. A new ABC transporter mediating the detachment of lipid-modified proteins from membranes... known. The secretion of most bacteriocins occurs via dedicated ABC-transporters (26) while some can... protein LciA (58). In some cases ABC-transporters have been shown to be ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
74 Develop. Growth Differ. (2006) 48, 559573 doi: 10.1111/j.1440-169x.2006.00893.x Blackwell Publishing Asia
 

Summary:  is similar to the multidrug resistance (MDR) activity mediated by ATP binding cassette (ABC) efflux... Publishing Asia Increase in multidrug transport activity is associated with oocyte maturation in sea stars... and PGP-specific transporter inhibitors. Key words: multidrug resistance, ...

  

Source: 

 

Collection: Environmental Sciences and Ecology

 
75 Molecular & Biochemical Parasitology 130 (2003) 8390 Functional genetic identification of PRP1, an ABC transporter superfamily
 

Summary:  , an ABC transporter superfamily member conferring pentamidine resistance in Leishmania major Adriano C... -glycoprotein (PGP)/MRP ATP-binding cassette (ABC) transporter superfamily that we named pentamidine resistance... target of PEN action in kinetoplastids, and that PEN Abbreviations: ABC, ATP-binding cassette; kb

  

Source: Beverley, Stephen M. - Department of Molecular Microbiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
76 Bock et al. 2006 Family Summary 1.A.1 Voltage-gated Ion ChannVIC 36 34 2
 

Summary:  107 93 957 3.A.1.201 Multidrug Resistance ExpoABC 102 putative multidrug-resistance protein, P... 1 1026 3.A.1.208 Conjugate Transporter ABC 675 multidrug-resistance related protein, ABC transporter... , thylakoid memb 1 1 693 2.A.66 ...

  

Source: Sze, Heven - Department of Cell Biology and Molecular Genetics, University of Maryland at College Park

 

Collection: Biology and Medicine

 
77 Mutation Research 552 (2004) 101117 Emerging contaminants--pesticides, PPCPs, microbial
 

Summary:  activity of transmembrane proteins belonging to the ATP binding cassette (ABC) [11,12] superfamily, which... . The best stud- ied ABC protein is the P-glycoprotein (P-gp), a large protein found in the cell membrane... the multidrug resistance (MDR) phenomenon [13,14]. Since the phenomenon of P-gp-mediated MDR is a major obstacle

  

Source: 

 

Collection: Environmental Sciences and Ecology

 
78 Lipid rafts : dream or reality for cholesterol transporters ? Stphane ORLOWSKI1
 

Summary:  remain to be clarified. Keywords: lipid rafts, cholesterol transport, ABC proteins, SR-BI, NPC1L1... , intestinal absorption. Abbreviations: ABC: ATP-binding cassette; ACAT: acyl-coenzyme A... : low density lipoprotein; LXR: liver X receptor ; (M)CD: (methyl)-cyclodextrin; MDR: multidrug

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
79 N-Linked Glycosylation of the Human ABC Transporter ABCG2 on Asparagine 596 Is Not Essential for Expression, Transport Activity, or Trafficking to the
 

Summary:  into or out of cells (3). ABC transporters known to be involved in mammalian multidrug resistance are P... neither the drug transport function of ABC multidrug transporters, P-gp and MRP1, nor the substrate... . Ejendal, K. F., and Hrycyna, C. A. (2002) Multidrug resistance and cancer: ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
80 The crystal structure of MexR from Pseudomonas aeruginosa in complex with its antirepressor ArmR
 

Summary:  that overexpress multidrug efflux pumps such as the prominent drug-proton antiporter, MexAB-OprM. The primary... into the regulation of multidrug resistance. gene regulation MarR mexAB-oprM PA3719 protein peptide Bacterial... multidrug efflux pumps confer widespread antibi- otic resistance by actively purging their cells

  

Source: McIntosh, Lawrence P. - Department of Biochemistry and Molecular Biology, University of British Columbia

 

Collection: Biotechnology ; Biology and Medicine


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81 Molecular Biology of the Cell Vol. 7, 1485-1498, October 1996
 

Summary:  man multidrug resistance (MDR1) gene (Gottesman Research. © 1996 by The American Society for Cell... a 170-kDa protein, termed P-glycopro- tein (Pgp) or the multidrug transporter, which is ex- pressed... on the plasma membranes of multidrug-resis- tant (MDR) cells. P-glycoprotein is a 1280-amino-acid protein

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
82 [CANCER RESEARCH 61, 66356639, September 15, 2001] Advances in Brief
 

Summary:  , because an inhibitor increased accumulation of topotecan in the fetus in mice lacking the multidrug... : (301) 402-0172; E-mail: sebates@helix.nih.gov. 2 Internet address: http://www.gene.ucl.ac.uk/users/hester/abc... ; this is one of the first examples of an ABC transporter exhibiting a gain of function mutation upon selection

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
83 The ABC of ABC-transport in the hyperthermophilic
 

Summary:  The ABC of ABC-transport in the hyperthermophilic archaeon Pyrococcus furiosus #12;This work... ;RIJKSUNIVERSITEIT GRONINGEN The ABC of ABC-transport in the hyperthermophilic archaeon Pyrococcus furiosus... by an inducible, high-affinity ABC-transporter 25 Chapter 3 Biochemical evidence ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
84 Human P-Glycoprotein Exhibits Reduced Affinity for Substrates during a Catalytic Transition State
 

Summary:  and purified/reconstituted systems (8-12). Energy-dependent transport mediated by Pgp has been demonstrated... ), a plasma membrane protein that confers multidrug resistance, functions as an ATP-dependent drug efflux pump... . Multidrug resistance, which is a major hurdle in successful cancer chemotherapy, is ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
85 Copyright 2004 by the American Society for Biochemistry and Molecular Biology, Inc. 1256 Journal of Lipid Research Volume 45, 2004 This article is available online at http://www.jlr.org
 

Summary:  of the compounds that caused a half-maximal inhibition of lipid transport mediated by either ABCA1 or SR-BI. Cross... to inhibit lipid transport mediated by ABCA1 and SR-BI, there are several striking differences... -mediated endocytic uptake of LDL receptors (22). The binding of native spherical HDL par- ...

  

Source: Kirchhausen, Tomas - Immune Disease Institute & Department of Cell Biology, Harvard University

 

Collection: Biology and Medicine

 
86 Summary and concluding ESEARCH on the structure and function of substrate-binding proteins (SBPs)
 

Summary:  , and have diverse functions. Many, like Sav1866 and P-gp are involved in multi-drug extrusion. ABC importers... -binding proteins (SBPs) of ATP Binding Cassette (ABC) transporters has been ongoing for at least four decades. Our... on the lactococcal oligopeptide binding protein A (OppA), the receptor component of the ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
87 Copyright 2007 by the Genetics Society of America DOI: 10.1534/genetics.107.080689
 

Summary:  -binding cassette (ABC) transporter homologous to mammalian multidrug resistance proteins, functions... granules. mrp-4 encodes a member of the multidrug resistance protein (MRP)/ABCC ABC transporter family. MRP... of the Caenorhabditis elegans Multidrug Resistance Gene, mrp-4, in Gut ...

  

Source: Hermann, Greg J. - Department of Biology, Lewis and Clark College

 

Collection: Biology and Medicine

 
88 THEORETICAL STUDY ON SOME -LACTAMS AS SUBSTRATES OF THE BACTERIAL MULTIDRUG RESISTANCE ACRB PUMP
 

Summary:  THEORETICAL STUDY ON SOME -LACTAMS AS SUBSTRATES OF THE BACTERIAL MULTIDRUG RESISTANCE ACRB PUMP... B pump is a part of the most important multidrug efflux system of gram-negative bacteria, which excretes

  

Source: Ferreira, Márcia M. C. - Instituto de Química, Universidade Estadual de Campinas

 

Collection: Chemistry

 
89 Fall 2011 Seminar Schedule Aug. 26 Valerie Copie, Montana State University
 

Summary:  Katherine Henzler-Wildman, Washington University (Lee) "Conformational exchange in the small multidrug... resistance transporter, EmrE: Insights into the mechanism of multidrug eflux" Sept. 16 Gower Research Award

  

Source: Southern Illinois University, Fisheries and Illinois Aquaculture Center

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
90 Regulation of multidrug resistance in Lactococcus Herfita Agustiandari
 

Summary:  Regulation of multidrug resistance in Lactococcus lactis Herfita Agustiandari 2009 #12;ISBN: 978... . Jurriaanse Stichting, the Netherlands #12;RIJKSUNIVERSITEIT GRONINGEN Regulation of multidrug resistance

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
91 1. Ajouz, B., C. Berrier, A. Garrigues, M. Besnard, and A. Ghazi. 1998. Release of thioredoxin via the mechanosensitive channel MscL during osmotic downshock of Escherichia coli cells. J.Biol.Chem. 273:26670-
 

Summary:  . Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC... . Dassa, E. and P. Bouige. 2001. The ABC of ABCS: a phylogenetic and functional classification of ABC... subunit of the trehalose/maltose ABC transporter of the ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
92 Response to "PREDICTABLE DIFFICULTY OR DIFFICULTY TO PREDICT" by Tams Arnyi, Krisztina Fulop, Orsolya Symmons, Viola Pomozi, and Andrs Vradi
 

Summary:  automated bioinformatics tool, we recently classified 40 point mutations in ABC transporters as "neutral... -altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assay. PLo... and the multidrug resistance protein 3 associated with drug-induced liver injury. Pharmacogenet Genomics 17

  

Source: Sali, Andrej - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine ; Biotechnology

 
93 Evidence That Release of Adenosine Triphosphate From Endothelial Cells During Increased Shear Stress Is Vesicular
 

Summary:  transmembrane regulator, the sulfonylurea receptor, and the multidrug resistance protein showed no involvement... - tion that release from some non-neuronal cells may not be by exocytosis (6): ATP-binding cassette (ABC... the effects of inhibitors on three ABC proteins previously identified in endothelial cells (12­ 14

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
94 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, July 2008, p. 26162625 Vol. 52, No. 7 0066-4804/08/$08.00 0 doi:10.1128/AAC.01643-07
 

Summary:  . Whole-Genome Pyrosequencing of an Epidemic Multidrug-Resistant Acinetobacter baumannii Strain Belonging... /Accepted 8 April 2008 The whole-genome sequence of an epidemic, multidrug-resistant Acinetobacter baumannii... is the main advantage of A. baumannii in the nosocomial environment (15). Multidrug- resistant clones of A

  

Source: Dever, Jennifer A. - Biology Department, University of San Francisco

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
95 Genetics of a-amanitin resistance in a natural population of Drosophila melanogaster
 

Summary:  ). Multidrug resistance genes (also referred to as P-glycoproteins) are members of the ABC-transporter gene... polymor- phism in a multidrug resistance gene (Mdr65A) in a-amanitin resistance. However... , the underlying cause is a gene regulatory mutation. Keywords: evolution, Mdr65A, multidrug resistance, P

  

Source: Begun, David - Section of Evolution and Ecology, University of California, Davis

 

Collection: Environmental Sciences and Ecology

 
96 Beer Spoilage Bacteria Hop Resistance
 

Summary:  by the ATP-Binding Cassette Multidrug Transporter HorA 49 CHAPTER 6 The Membrane Bound ATPase Contributes

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
97 UNIVERSITE JOSEPH FOURIER -GRENOBLE I ECOLE DOCTORALE CHIMIE ET SCIENCES DU VIVANT
 

Summary:  Biologie Structurale et Nanobiologie Carmen GALIÁN BARRUECO Caractérisation de 2 transporteurs ABC ("ATP... précieuses à Manuela, de renouveler le dynamisme des ABCs à Paris à l'équipe lyonnaise, Pierre, Fred, Rima... 'émergence du phénotype MDR (« multidrug resistance ») des cellules cancéreuses est souvent ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
98 Published on Web Date: October 21, 2010 r 2010 American Chemical Society 82 DOI: 10.1021/cn100078a |ACS Chem. Neurosci. (2011), 2, 8289
 

Summary:  of the multidrug resistance-linked ABC drug transporter, ABCG2. Biochemistry 45, 8940­8951. 33. Ambudkar, S. V... P-gp, breast cancer resistance protein (BCRP, ABCG2), and multidrug resistance protein 1 (MRP1, ABCC... transporters belonging to the ATP-bind- ing cassette (ABC) family, which are highly ...

  

Source: Pike, Victor W. - Molecular Imaging Branch, National Institute of Mental Health

 

Collection: Biology and Medicine

 
99 BioMed Central Page 1 of 11
 

Summary:  ,31]. Fifteen members of the Arabidopsis ABC transporters belong to the multidrug resistance-associated protein... : the multidrug-resistance related protein (MRP) ABC transporter genes in Arabidop- sis thaliana. Planta 2002, 216... author Abstract Background: ABC proteins constitute one ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
100 Published: July 19, 2011 r 2011 American Chemical Society 6132 dx.doi.org/10.1021/ac201690t |Anal. Chem. 2011, 83, 61326134
 

Summary:  . Chem. 2011, 83, 6132­6134 LETTER pubs.acs.org/ac Single-Cell-Kinetics Approach to Compare Multidrug... , Ontario M3J 1P3, Canada bS Supporting Information Multidrug resistance (MDR) due to active drug efflux... -associated drug efflux is driven by a superfamily of ATP-binding cassette (ABC) plasma membrane transporters.2

  

Source: Krylov, Sergey - Department of Chemistry, York University (Toronto)

 

Collection: Biology and Medicine ; Chemistry


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