| Sample search results for: a2 receptor-deficient mice |
| 1 | Failure of Intravenous Morphine to Serve as an Effective Instrumental Reinforcer in Dopamine D2 Receptor Knock-Out Mice | ||
|
Summary: al., 1996), and receptor-deficient mice (Elmer et al., 1995), the role of dopamine has not been... examined using dopa- mine receptor-deficient mice in the self-administration model. In the three studies... , Thiemann W, Loh HH, Hollt V (2000) Morphine self-administration in mu-opioid ... |
|||
|
Source: Journal Neuroscience -- Rapid Communications |
|||
|
Collection: Biology and Medicine |
|||
| 2 | Gonadal Pathologies in Transgenic Mice Expressing the Rat Inhibin -Subunit | ||
|
Summary: pathologies. Abbreviations: ERKO, E receptor-deficient mice; hCG, human CG; MT- , metallothionein-I promoter... -dependent hyperandrogenemia, precocious puberty, and hemorrhagic ovarian cysts (29, 30). E receptor- deficient mice (ERKO... exhibit a strikingly similar phenotype to both ... |
|||
|
Source: Mayo, Kelly E. - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University |
|||
|
Collection: Biology and Medicine |
|||
| 3 | Ahr Null Alleles: Distinctive or Different? Garet P. Lahvis and Christopher A. Bradfield* | ||
|
Summary: -hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity. Toxicol Appl... Inc. All rights reserved. PII S0006-2952(98)00134-8 #12;P4501A2, and decreased body size over... /a Cyp1a2 Not inducible Not inducible ... |
|||
|
Source: Bradfield, Christopher A. - McArdle Laboratory for Cancer , University of Wisconsin at Madison |
|||
|
Collection: Biology and Medicine |
|||
| 4 | Atherosclerosis 214 (2011) 5864 Contents lists available at ScienceDirect | ||
|
Summary: atherosclerosis in aortic arches/thoracic aortas, but not aortic roots of LDL receptor-deficient mice fed a high... in myocardial ischemia/reperfusion injury in group X secretory phospholipase A2-deficient mice. Circulation 2008... phospholi- pase ... |
|||
|
Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle |
|||
|
Collection: Chemistry ; Biology and Medicine |
|||
| 5 | Genes, Brain and Behavior (2007) # 2007 The Authors Journal compilation # 2007 Blackwell Publishing Ltd | ||
|
Summary: PLCb1À/À mice tested ever reached the criterion within 28 days (Fig. 6, a1, a2). However, all PLCb1À... trained on DNMTS T-maze task. (a1), (a2) All the wild- type mice (WT, n ¼ 8) tested reached the criterion... dopaminergic transmission, and response to ... |
|||
|
Source: Kim, Daesoo - Department of Biological Sciences, Korea Advanced Institute of Science and Technology |
|||
|
Collection: Biology and Medicine |
|||
| 6 | TOXICOLOGICAL SCIENCES 106(1), 8392 (2008) doi:10.1093/toxsci/kfn149 | ||
|
Summary: ). Lesions of aryl-hydrocarbon receptor-deficient mice. Vet. Pathol. 34, 605614. Ge, N. L., and Elferink, C... and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice. Proc. Natl. Acad. Sci. U. S... , J. J., Potter, S. S., Puga, A., and Nebert, D. W. (1996). ... |
|||
|
Source: Bradfield, Christopher A. - McArdle Laboratory for Cancer , University of Wisconsin at Madison |
|||
|
Collection: Biology and Medicine |
|||
| 7 | The role of the dioxin-responsive element cluster between the Cyp1a1 and Cyp1a2 loci in aryl | ||
|
Summary: -induced hepatotoxicity than WT mice. The results of parallel toxicologic studies using individual Cyp1a1 and Cyp1a2 null... . Given the 100% penetrance of patent DV in Ahr null mice, these results indicate that Cyp1a1 and Cyp1a2... Null Mice. ... |
|||
|
Source: Bradfield, Christopher A. - McArdle Laboratory for Cancer , University of Wisconsin at Madison |
|||
|
Collection: Biology and Medicine |
|||
| 8 | C. Betancur et al. 1 Neurotensin gene expression and behavioral responses following | ||
|
Summary: of psychostimulants and antipsychotic drugs in dopamine D3 receptor deficient mice Catalina Betancur,* M.D., Ph... receptor deficient mice (Accili et al. 1996; Xu et al. 1997; Boulay et al. 1999). Our results indicate... was similar in the three genotypes. Wild-type ... |
|||
|
Source: Ecole Polytechnique, Centre de mathématiques |
|||
|
Collection: Mathematics |
|||
| 9 | D3 receptor knockout mice have altered circadian gene expression patterns in spinal sympathetic preganglionic neurons | ||
|
Summary: expression patterns between wild type (WT) and D3 receptor deficient mice (D3KO), using a combination... D3 receptor knockout mice have altered circadian gene expression patterns in spinal sympathetic... of fluorescent reporters, laser-capture microdissection and DNA microarrays. Adult male ... |
|||
|
Source: Hochman, Shawn - Department of Physiology, Emory University |
|||
|
Collection: Biology and Medicine |
|||
| 10 | Secretory Phospholipase A2 A Multifaceted Family of | ||
|
Summary: - expressed group IIA secretory phospholipase A2 increases atherosclerotic lesion formation in LDL receptor-deficient... these transgenic mice into LDL, receptor-deficient mice increased atherosclerotic lesion formation. Furthermore... increased foam cell formation in ... |
|||
|
Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle |
|||
|
Collection: Chemistry ; Biology and Medicine |
|||
| 11 | 208 VOLUME 4 NUMBER 2 | MARCH 2011 | www.nature.com/mi ARTICLES nature publishing group | ||
|
Summary: , these data suggest that the higher pathogen load seen in chemokine receptor-deficient mice is not because... . trachomatis-specific chemokine receptor-deficient mice by breeding NR1 transgenic mice with either CCR5... protective immunity in gamma interferon ... |
|||
|
Source: Starnbach, Michael - Department of Microbiology and Molecular Genetics, Harvard University |
|||
|
Collection: Biology and Medicine |
|||
| 12 | IL-4 is required to prevent filarial nematode development in resistant but not susceptible strains of mice | ||
|
Summary: ) or is not modified ( ¼ ) in IL-4 deficient or IL-4 receptor deficient (*) mice compared with WT mice. 0, No parasite... (Sigma), IL-10 (Genzyme) and IFNg (Sigma). The capture and detection antibodies used were: IFNg, R46A2... of mice Laetitia ... |
|||
|
Source: Allen, Judith - School of Biological Sciences, University of Edinburgh; Read, Andrew - Center for Infectious Disease Dynamics & Department of Entomology, Pennsylvania State University |
|||
|
Collection: Biology and Medicine ; Environmental Sciences and Ecology |
|||
| 13 | Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer | ||
|
Summary: on day 5 (Figure S1B). However, Casp1À/À mice displayed more severe signs of injury (Figures 2A2D... (Figures 2A2C), whereas AscÀ/À mice had some remaining erosions, but unlike Casp1À/À mice, showed signs... of re-epithelialization ... |
|||
|
Source: Iowa Center for Gene Therapy |
|||
|
Collection: Biotechnology ; Biology and Medicine |
|||
| 14 | Spielewoy et al. 1 Increased Rewarding Properties of Morphine | ||
|
Summary: ) have not been replicated and a recent study using D2 receptor deficient mice did not report any changes... or A2a receptors enhences D1 receptor-mediated effects on c-fos expression. J. Neurosci., 17, 8038... Spielewoy et al. 1 Increased Rewarding Properties of Morphine in ... |
|||
|
Source: Ecole Polytechnique, Centre de mathématiques |
|||
|
Collection: Mathematics |
|||
| 15 | MOLECULAR AND CELLULAR BIOLOGY, 0270-7306/01/$04.00 0 DOI: 10.1128/MCB.21.14.47484760.2001 | ||
|
Summary: February 2001/Accepted 15 April 2001 Thyroid hormone receptors are encoded by the TR (NR1A1) and TR (NR1A2... inactivation in mice has provided new insights into the functional complexity of these products. Different... the molecular basis for these alterations, we generated mice devoid of all known isoforms ... |
|||
|
Source: Ecole Polytechnique, Centre de mathématiques |
|||
|
Collection: Mathematics |
|||
| 16 | Glutamate Receptors on Dopamine Neurons Control the Persistence of Cocaine Seeking | ||
|
Summary: with a single dose of cocaine or saline (Figures 2A, 2B, and S2). We then used these observations to calculate... remains elusive. Here, we gener- ated mice lacking the GluR1, GluR2, or NR1 receptor subunits selectively... in dopamine neurons. We report that in midbrain slices of cocaine-treated mice, ... |
|||
|
Source: Durstewitz, Daniel - Research Group Computational Neuroscience, Central Institute of Mental Health, |
|||
|
Collection: Computer Technologies and Information Sciences ; Biology and Medicine |
|||
| 17 | Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor- | ||
|
Summary: - deficient mice Garet P. Lahvis*, Susanne L. Lindell , Russell S. Thomas*, Robert S. McCuskey , Christopher... most known for their role in xenobiotic metabolism (e.g., Cyp1a1, Cyp1a2, Cyp1b1, etc... Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon ... |
|||
|
Source: Bradfield, Christopher A. - McArdle Laboratory for Cancer , University of Wisconsin at Madison |
|||
|
Collection: Biology and Medicine |
|||
| 18 | TheJournalofExperimentalMedicine JEM The Rockefeller University Press $15.00 | ||
|
Summary: of CD45.2 cells between the two stages of T cell differentiation as follows: P(AB) = B2(100 - A2)/(A2... A to a stage B relative to CD45.2 cells, A2 is the percentage of CD45.2 cells at stage A, and B2... mutant mice with a loss of function ... |
|||
|
Source: Littman, Dan - Skirball Institute of Biomolecular Medicine & Department of Microbiology, New York University |
|||
|
Collection: Biology and Medicine |
|||
| 19 | Cell Metabolism Short Article | ||
|
Summary: ) the role of CHOP in apoptosis of ER-stressed cultured macrophages (Feng et al., 2003a) (Figure 3A); (2... 10 mg/ml of the ACAT inhibitor 58-035 (Yao and Tabas, 2000; Feng et al., 2003a); (2) incubation... ., and Tall, A.R. (2006). Macrophage insulin receptor ... |
|||
|
Source: Tabas, Ira - Department of Physiology and Cellular Biophysics, Columbia University |
|||
|
Collection: Biology and Medicine |
|||
| 20 | INFECTION AND IMMUNITY, 0019-9567/97/$04.00 0 | ||
|
Summary: Infection as Demonstrated in T-Cell-Receptor-Deficient Mice of Defined Ity Genotypes BENNETT C. WEINTRAUB,1... against Mycobacterium bovis bacillus Calmette Guerin: studies with T cell receptor-deficient mutant mice... ( T cells or T cells, respectively) in the host defense against Salmonella using ... |
|||
|
Source: Hedrick, Stephen M. - Division of Biological Sciences, University of California at San Diego |
|||
|
Collection: Biology and Medicine |
|||
| 21 | BioMed Central Page 1 of 16 | ||
|
Summary: receptor-deficient mice after progesterone administration. Endocrinology 2000, 141:2691-2697 11. Das SK... PRL receptor deficiency, we analyzed in detail ovarian and corpora lutea development of PRLR... -/- female [10]. To better understand PRL receptor deficiency, we ... |
|||
|
Source: Ecole Polytechnique, Centre de mathématiques |
|||
|
Collection: Mathematics |
|||
| 22 | ORIGINAL ARTICLE Passive transfer of streptococcus-induced antibodies | ||
|
Summary: -hemolytic streptococcus matrix (M) protein and cross-react with molecular targets complement C4 protein and a-2... and immunoprecipitated C4 complement protein and a-2-macroglobulin.28 Striatal IgG deposits were also found (Yaddanapudi... interaction in PANDAS mice, replicating more ... |
|||
|
Source: Columbia University - Jerome L. and Dawn Greene Infectious Disease Laboratory |
|||
|
Collection: Biology and Medicine |
|||
| 23 | PPAR gene level differently affects lipid metabolism and inflammation in apolipoprotein E2 knock-in mice | ||
|
Summary: -19Apr2011 #12;15 atherosclerosis in low-density lipoprotein receptor-deficient mice. Circulation. 2007... insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice. Mol Cell Biochem. 2006... established that nuclear-receptor deficiency does not ... |
|||
|
Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique |
|||
|
Collection: Physics |
|||
| 24 | Reprint from Handbook of Experimental Pharmacology, Vol. 175 | ||
|
Summary: muscarinic acetylcholine receptor-deficient mice. Proc Natl Acad Sci U S A 98:15312 15317 Goldman ME... for Sustaining Cholinergic Signaling as Revealed in Studies of Genetically Altered Mice M. H. Bazalakova · R. D... Upregulation Provides Mechanism of Compensation in ChAT+/- Mice . 536 2.5 CHT ... |
|||
|
Source: Blakely, Randy - Department of Pharmacology, Vanderbilt University |
|||
|
Collection: Biology and Medicine |
|||
| 25 | ISSN: 1524-4636 Copyright 2009 American Heart Association. All rights reserved. Print ISSN: 1079-5642. Online | ||
|
Summary: receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice... a modest impact on overall atherosclerosis lesion area, we found that scavenger receptor deficiency causes... . Boyanovsky BB, van der Westhuyzen DR, Webb NR. Group V secretory ... |
|||
|
Source: Tabas, Ira - Department of Physiology and Cellular Biophysics, Columbia University |
|||
|
Collection: Biology and Medicine |
|||
| 26 | Cyp1b1 exerts opposing effects on intestinal tumorigenesis via exogenous and endogenous substrates | ||
|
Summary: A2, Cox1, Cox2, LpI, PPAR, and PPAR, affect the multiplicity of intestinal tumors in Min mice (4... , Baglole CJ, et al. Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses... , 1A2, and 1B1 by polycyclic aromatic ... |
|||
|
Source: Dove, William - McArdle Laboratory for Cancer & Department of Medical Genetics, University of Wisconsin at Madison |
|||
|
Collection: Biology and Medicine |
|||
| 27 | Cell Metabolism Impaired Regulation of Hepatic Glucose | ||
|
Summary: intercrossed insulin receptor-deficient (InsrÀ/À ) and l-Foxo1 mice to obtain double knockouts (Dko) lacking... .C., Dragatsis, I., and Accili, D. (2004). Transgenic rescue of insulin receptor-deficient mice. J. Clin. Invest... induced glycogenolytic (G6pc) and gluconeoge- netic genes (Pck1 and ... |
|||
|
Source: Rosenberg, Noah - Departments of Human Genetics & Biostatistics, University of Michigan |
|||
|
Collection: Biotechnology |
|||
| 28 | Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus | ||
|
Summary: hippocampal functions, we used mice with a targeted deletion of the 5-HT1A-receptor gene (31). 5-HT1A-receptor-deficient... , such as depression and posttraumatic stress disorder and panic disorder (14). In par- ticular, a receptor deficiency... to specify whether 5-HT1A-receptor ... |
|||
|
Source: Sibille, Etienne - Center for the Neural Basis of Cognition & Department of Psychiatry, University of Pittsburgh |
|||
|
Collection: Biology and Medicine |
|||
| 29 | Hindawi Publishing Corporation Neural Plasticity | ||
|
Summary: or contextual conditioning [48] GABA-A 2 subunit HZ mice cued fear conditioning, 0 spatial memory [49... emotional behavior in PACAP-type- I-receptor-deficient mice," Molecular Brain Research, vol. 92, no. 1-2, pp... -term potentiation and associative learn- ing in pituitary adenylate ... |
|||
|
Source: Kalueff, Allan V. - Department of Pharmacology, Tulane University |
|||
|
Collection: Biology and Medicine |
|||
| 30 | IL-4R signaling is required to induce IL-10 for the establishment of Th2 dominance | ||
|
Summary: (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice... of antagonistic anti-IL-12 (clone C17.8, BD PharMingen) and anti-IFNc (clone R4-6A2, BD PharMingen) mAb or control... helminth infection (2224). Thus, both IL-10ÿ/ÿ and IL-4/IL-10-doubly deficient ... |
|||
|
Source: Maizels, Rick - School of Biological Sciences, University of Edinburgh |
|||
|
Collection: Environmental Sciences and Ecology |
|||
| 31 | Cell Metab . Author manuscript CXC ligand 5 is an adipose-tissue derived factor that links obesity to | ||
|
Summary: receptor-deficient mice results in increased insulin sensitivity in these mice (Weisberg et ). A recent... , liver and muscle from 6-month-old C57Bl/6 mice (n 3).A. = 2-deoxy-glucose uptakeB. in isolated soleus... with recombinant CXCL5 blocks insulin-stimulated ... |
|||
|
Source: Ecole Polytechnique, Centre de mathématiques |
|||
|
Collection: Mathematics |
|||
| 32 | Immunity, Vol. 8, 439449, April, 1998, Copyright 1998 by Cell Press A Role for FADD in T Cell | ||
|
Summary: (%) n CD4 (%) CD8 (%) n 2 5.8 1.6 2.2 0.62 3 3.6 1.6 1.3 0.5a 4 3 11.8 1.5 5.9 0.5 2 6.6 1.1a 2.0 1.1a 2... produced transgenic mice coreceptor involved in negative selection.expressing a dominantly interfering... effector do- mocyte cell death include members of the tumor necro-main, as ... |
|||
|
Source: Hedrick, Stephen M. - Division of Biological Sciences, University of California at San Diego |
|||
|
Collection: Biology and Medicine |
|||
| 33 | Research Signpost 37/661 (2), Fort P.O., Trivandrum-695 023, Kerala, India | ||
|
Summary: the pig ureter, while intravesical adenosine via A2B receptors on smooth muscle [6]. ATP and adenosine... by receptor antagonism with suramin [12]. There was also reduced sensory nerve activity in P2X3 receptor-deficient... infiltration, collagen deposition and apoptosis in response to ureteral obstruction in ... |
|||
|
Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London |
|||
|
Collection: Biology and Medicine |
|||
| 34 | Liver Deformation in Ahr-Null Mice: Evidence for Aberrant Hepatic Perfusion In Early Development | ||
|
Summary: , Sundberg JP, and Gonzalez FJ (1997) Lesions of aryl-hydrocarbon receptor-deficient mice. Vet Pathol 34... vascular structures in Ah-receptor deficient mice. Proc Natl Acad Sci USA 97: 1044210447. Lahvis GP... Liver Deformation in Ahr-Null Mice: Evidence for ... |
|||
|
Source: Bradfield, Christopher A. - McArdle Laboratory for Cancer , University of Wisconsin at Madison |
|||
|
Collection: Biology and Medicine |
|||
| 35 | INFECTION AND IMMUNITY, 0019-9567/98/$04.00 0 | ||
|
Summary: subsequent reinfection to the same extent as control IFN- / mice. Experiments using IFN- receptor- deficient... receptor-deficient mice despite a strong local immuno- globulin A response. Infect. Immun. 65:10321044. 11... June 1998/Accepted 7 August 1998 In this study, we used ... |
|||
|
Source: Starnbach, Michael - Department of Microbiology and Molecular Genetics, Harvard University |
|||
|
Collection: Biology and Medicine |
|||
| 36 | Behavioural Brain Research 164 (2005) 206213 Research report | ||
|
Summary: homozygous, heterozygous and CB1 receptor deficient mice would display differences in their alcohol... DK. Ethanol-conditioned place preference is reduced in dopamine D2 receptor-deficient mice. Pharmacol... ,41] and ethanol sensitivity [39] and with- drawal symptoms completely absent in ... |
|||
|
Source: Brookhaven National Laboratory, Environmental Chemistry Division, Department of Applied Science |
|||
|
Collection: Environmental Sciences and Ecology |
|||
| 37 | Journal of Steroid Biochemistry & Molecular Biology 104 (2007) 269273 Aberrant nest building and prolactin secretion in | ||
|
Summary: and in dopamine D2 receptor- deficient mice [37,39]. Finally, dopamine is one of the major prolactin... egg development and embryo implantation in prolactin receptor- deficient mice after progesterone... hyperplasia and chronic hyperprolactinemia in dopamine d2 ... |
|||
|
Source: Kalueff, Allan V. - Department of Pharmacology, Tulane University |
|||
|
Collection: Biology and Medicine |
|||
| 38 | PPAR activation differently affects microparticle content in atherosclerotic lesions and liver of a mouse model of atherosclerosis and NASH | ||
|
Summary: treatment inhibited atherosclerosis lesion progression (figures 2A, 2B), and under these conditions, also... reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient... and plasma during atherosclerosis and NASH progression in apoE2-KI mice, and 2) to study ... |
|||
|
Source: Ecole Polytechnique, Centre de mathématiques |
|||
|
Collection: Mathematics |
|||
| 39 | Endogenous Hepatic Expression of the Hepatitis B Virus X-Associated Protein 2 Is Adequate for Maximal Association with | ||
|
Summary: with AHR / mice displayed -NF-induced increases in expres- sion of CYP1A1, UGT1A2, NQO1, and NRF2 (data... in constitutive or ligand-in- duced CYP1A1; CYP1A2; UDP glucuronosyltransferase 1A2; NAD(P)H dehydrogenase... the transcriptional induction ... |
|||
|
Source: Perdew, Gary - Department of Veterinary and Biomedical Sciences, Pennsylvania State University |
|||
|
Collection: Biology and Medicine |
|||
| 40 | ORIGINAL ARTICLE Phospholipase C-b1 knockout mice exhibit | ||
|
Summary: a complex pharmacology. Clozapine binds with high affinity to D4, 5-HT1A, 2A, a1 adrenergic, histamine H1... ORIGINAL ARTICLE Phospholipase C-b1 knockout mice exhibit endophenotypes modeling schizophrenia... implicated in the pathogenesis of schizophrenia. Here, we present data to show that PLC-b1 knockout ... |
|||
|
Source: Kim, Daesoo - Department of Biological Sciences, Korea Advanced Institute of Science and Technology |
|||
|
Collection: Biology and Medicine |
|||
| 41 | Mice Lacking D5 Dopamine Receptors Have Increased Sympathetic Tone and Are Hypertensive | ||
|
Summary: -targeting technology to create mice that lack this receptor subtype. We find that the D5 receptor- deficient mice... , 22(24):1080110810 Hollon et al. · D5 Receptor-Deficient Mice Exhibit Hypertension #12;thereafter... . Hollon et al. · D5 ... |
|||
|
Source: Ramachandran, Ramesh - Department of Veterinary and Biomedical Sciences, Pennsylvania State University |
|||
|
Collection: Biology and Medicine |
|||
| 42 | Altered Dopamine Release and Uptake Kinetics in Mice Lacking D2 Receptors | ||
|
Summary: receptor-deficient mice. Neuron 19:103113. Kennedy RT, Jones SR, Wightman RM (1992) Dynamic observation... of dopamine release in striatal synaptosomes of D2 receptor-deficient mice. Brain Res 792:253262. Limberger N... function in dopaminergic neu- rons from dopamine D2 receptor ... |
|||
|
Source: Sulzer, David - Departments of Neurology & Psychiatry, Columbia University |
|||
|
Collection: Biology and Medicine |
|||
| 43 | Altered Striatal Function and Muscarinic Cholinergic Receptors in Acetylcholinesterase Knockout Mice | ||
|
Summary: acetylcholine receptor-deficient mice. Proc Natl Acad Sci USA 98:1531215317. Gilmor ML, Nash NR, Roghani A... Mice LAURA A. VOLPICELLI-DALEY, ANNA HRABOVSKA, ELLEN G. DUYSEN, SHAWN M. FERGUSON, RANDY D. BLAKELY... the efficacy of cholinomimetics in treating disease. Acetylcholinesterase knockout (AChE / ) ... |
|||
|
Source: Blakely, Randy - Department of Pharmacology, Vanderbilt University |
|||
|
Collection: Biology and Medicine |
|||
| 44 | Proc. Natl. Acad. Sci. USA Vol. 95, pp. 1073410739, September 1998 | ||
|
Summary: in mice and found that receptor-deficient animals have an increased tendency to avoid a novel and fearful... , receptor-deficient mutant mice could provide im- portant information on predisposition toward these condi... -like behavior of receptor-deficient animals. This view is consistent ... |
|||
|
Source: Sibille, Etienne - Center for the Neural Basis of Cognition & Department of Psychiatry, University of Pittsburgh |
|||
|
Collection: Biology and Medicine |
|||
| 45 | Roubert et al. 1 Altered neurotensin mRNA expression in mice lacking the dopamine | ||
|
Summary: of psychostimulants and antipsychotic drugs in dopamine D3 receptor deficient mice. Neuropsychopharmacology 24, 170... likely an interspecies difference, since similar findings were reported recently in D3 receptor-deficient... Roubert et al. 1 Altered neurotensin mRNA expression in mice ... |
|||
|
Source: Ecole Polytechnique, Centre de mathématiques |
|||
|
Collection: Mathematics |
|||
| 46 | Bulletin of Mathematical Biology (2006) 68: 2232261 DOI 10.1007/s11538-006-9103-y | ||
|
Summary: are same as shown in Table 1. 5.4. IFN- receptor deficiency A genetic susceptibility to mycobacterial... and IFN- inhibition of IL-10 production. The average Mtb growth in the IFN- receptor deficiency... the models of normal re- sponse and IFN- receptor deficiency is ... |
|||
|
Source: New Mexico, University of - Santa Fe Institute & Department of Computer Science, Computer Immune Systems Group |
|||
|
Collection: Biology and Medicine ; Computer Technologies and Information Sciences |
|||
| 47 | Behavioral/Systems/Cognitive CNS Leptin Action Modulates Immune Response | ||
|
Summary: - sis. Specifically, we tested whether survival of globally leptin receptor-deficient (db/ db) mice... at CNS leptin receptors. It seems intriguing that leptin receptor- deficient db/db mice seem to show re... for the difference in survival may be that db/db mice are ... |
|||
|
Source: Toledo, University of - Center for Diabetes and Endocrine Research (CeDER) |
|||
|
Collection: Biology and Medicine |
|||
| 48 | Fergani et al. 1/37/ Increased peripheral lipid clearance in an animal model of Amyotrophic | ||
|
Summary: ) receptor-deficient mice have reduced lipoprotein lipase activity. Possible causes of hypertriglyceridemia... and reduced body mass with VLDL receptor deficiency. J Biol Chem 277:10037-10043. 35. Drover, V.A., M. Ajmal... in amyotrophic lateral sclerosis mice Journal of Lipid Research, ... |
|||
|
Source: Ecole Polytechnique, Centre de mathématiques |
|||
|
Collection: Mathematics |
|||
| 49 | J. Exp. Med. The Rockefeller University Press 0022-1007/2000/08/439/08 $5.00 Volume 192, Number 3, August 7, 2000 439446 | ||
|
Summary: -mail: luster@helix.mgh.harvard.edu #12;440 LTB4 Receptordeficient Mice (PPAR) (11). Whereas BLTR appears... . #12;442 LTB4 Receptordeficient Mice mice homozygous for the disrupted allele. Mice were gen- otyped... in four BLTR / mice; n 19 ... |
|||
|
Source: von Andrian, Ulrich H. - Immune Disease Institute & Department of Pathology, Harvard University |
|||
|
Collection: Biology and Medicine |
|||
| 50 | Endothelium-Derived Vasoconstriction by Purines and Pyrimidines | ||
|
Summary: . 2004;143: 611617. 11. Vial C, Evans RJ. P2X1 receptor-deficient mice establish the native P2X receptor... , prostaglandin H2, thromboxane A2, and superoxide anions.6,7 To¨lle et al1 present compelling evidence... In P2X1 knockout mice, the vasoconstrictor response to ATP released by ... |
|||
|
Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London |
|||
|
Collection: Biology and Medicine |
|||
| 51 | Abnormal cardiac function associated with sympathetic nervous system hyperactivity in mice | ||
|
Summary: -ARs in mice leads to chronically elevated sympathetic tone (18). Here we report that 2A/ 2C-AR knockout (KO... of mice having a uniform, predominantly C57Bl6/J genetic background. 2A/ 2C-ARKO mice were generated... combina- tions of 2A- and 2C-AR ... |
|||
|
Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University |
|||
|
Collection: Biology and Medicine |
|||
| 52 | Introduction The localization of both lymphocytes and macrophages | ||
|
Summary: chemoattractant Protein-1 reduces atherosclerosis in low density lipoprotein receptor deficient mice. Mol. Cell. 2... :10491056. 18. de Winther, M.P., et al. 1999. Scavenger receptor deficiency leads to more complex... with the descriptive evaluation of human tissues, studies in ... |
|||
|
Source: Dworkin, Jonathan - Department of Microbiology, Columbia University; Schindler, Christian - Department of Microbiology, Columbia University |
|||
|
Collection: Biology and Medicine |
|||
| 53 | BRIEF REVIEWS Of Mice and Not Men: Differences between Mouse and | ||
|
Summary: *, IgG2b, IgG3, IgM * absent in C57BL/6, /10, SJL and NOD mice, which have IgG2c IgA1, IgA2, IgD, Ig... impaired in interleukin 7 receptor-deficient mice. J. Exp. Med. 180:1955. 36. Roifman, C. M., J. Zhang, D... the novel IgG2c (23). Humans in contrast express two subtypes of IgA--IgA1 ... |
|||
|
Source: Hughes, Christopher C. W. - Department of Molecular Biology and Biochemistry, University of California, Irvine |
|||
|
Collection: Biology and Medicine |
|||
| 54 | The Rockefeller University Press $30.00 J. Exp. Med. Vol. 208 No. 2 395-407 | ||
|
Summary: and Honjo, 2006; Keir et al., 2008). PD-1 knockout (Pdcd1/) mice develop lupus- like glomerulonephritis... to prevent autoimmunity in mice Taku Okazaki,1,2,3 Il-mi Okazaki,1 Jian Wang,3 Daisuke Sugiura,1 Fumio Nakaki... -induced cytidine deaminaselinked autoimmunity (aida) mice harbor a loss- of-function mutation in the gene ... |
|||
|
Source: Iowa Center for Gene Therapy |
|||
|
Collection: Biotechnology ; Biology and Medicine |
|||
| 55 | Genes, Brain and Behavior (2008) 7: 629638 # 2008 The Authors Journal compilation # 2008 Blackwell Publishing Ltd | ||
|
Summary: were placed in the chambers and received five 0.7-mA, 2-second unsignaled foot shocks on day 1... Publishing Ltd Exaggerated emotional behavior in mice heterozygous null for the sodium channel Scn8a (Nav1... voltage-gated sodium channel. Mice homozygous for mutations in the Scn8a gene exhibit motor impair- ... |
|||
|
Source: Meisler, Miriam - Department of Human Genetics, University of Michigan |
|||
|
Collection: Biology and Medicine |
|||
| 56 | Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: Effects on ethanol drinking | ||
|
Summary: Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: Effects on ethanol drinking... ), and receptor-deficient mice (Drd2À/À). Ethanol intake and preference were then determined using the two... preference is reduced in dopamine D2 receptor-deficient ... |
|||
|
Source: Brookhaven National Laboratory, Environmental Chemistry Division, Department of Applied Science |
|||
|
Collection: Environmental Sciences and Ecology |
|||
| 57 | Immunity, Vol. 21, 781791, December, 2004, Copyright 2004 by Cell Press A Deficiency in Drak2 Results | ||
|
Summary: apoptosis, we produced The signal transduction events leading to apoptosisDrak2 / mice. Contrary to our... , T cells from Drak2 / apoptosis promoted by the DAP-like family of kinases.mice exhibited enhanced... in lymphoid cells. In extensive Consequently, numerous mechanisms have evolved studies of Drak2 / mice, we |
|||
|
Source: Hedrick, Stephen M. - Division of Biological Sciences, University of California at San Diego |
|||
|
Collection: Biology and Medicine |
|||
| 58 | The Differential Fate of Mesonephric Tubular-Derived Efferent Ductules in Estrogen Receptor-Knockout | ||
|
Summary: inhibits the vascular injury response in estrogen receptor- deficient female mice. Proc Natl Acad Sci USA... - Knockout Versus Wild-Type Female Mice* CHERYL S. ROSENFELD, PAUL S. COOKE, THOMAS H. WELSH, JR., GRETCHEN... in female wild-type (WT) and estrogen receptor- knockout (ER KO) mice ... |
|||
|
Source: Hess, Rex A. - Department of Veterinary Biosciences, University of Illinois at Urbana-Champaign |
|||
|
Collection: Biology and Medicine |
|||
| 59 | letters to nature NATURE |VOL 406 |13 JULY 2000 |www.nature.com 199 | ||
|
Summary: PTH receptor-deficient mice, however, Gcm2-deficient mice are viable and fertile, and have only... receptor-deficient mice which have high serum PTH15 (Fig. 4a). In the face of a marked hypocalcaemia... source. a, Comparison of PTH serum levels in wild- type, Gcm2-deficient and Vitamin D ... |
|||
|
Source: Steinbach, Joe Henry - Washington University Pain Center & Department of Anesthesiology, Washington University in St. Louis |
|||
|
Collection: Biology and Medicine |
|||
| 60 | Temporal and Dose-Dependent Hepatic Gene Expression Patterns in Mice Provide New Insights into TCDD-Mediated Hepatotoxicity | ||
|
Summary: EXPRESSION IN TCDD-EXPOSED MICE 1059 #12;TCDD induction of Fabp4 and 5, Slc27a2, and Cd36 would facilitate... -metabolizing enzymes, including cytochrome P450s 1a1, 1a2, and 1b1. However, a significant role for cytochrome P450... that TCDD elicits gene- specific dose-dependent responses. ... |
|||
|
Source: Zacharewski, Timothy R. - Department of Biochemistry and Molecular Biology, Michigan State University |
|||
|
Collection: Biology and Medicine |
|||
| 61 | A Hypomorphic Allele of Aryl Hydrocarbon Receptor-Associated Protein-9 Produces a Phenocopy of the Ahr-Null Mouse | ||
|
Summary: -Salguero PM, Hilbert DM, Rudikoff S, Ward JM, and Gonzalez FJ (1996) Aryl-hydrocarbon receptor-deficient mice... , and Bradfield CA (2000) Portosystemic shunts and persistent fetal vascular structures in Ah-receptor deficient... shunt known as the ductus venosus (DV). Given that Ara9-null ... |
|||
|
Source: Bradfield, Christopher A. - McArdle Laboratory for Cancer , University of Wisconsin at Madison |
|||
|
Collection: Biology and Medicine |
|||
| 62 | TheJournalofExperimentalMedicine 2008 Lochner et al. | ||
|
Summary: ; biotinylated antiTCR- (GL3), CD25 (PC61.5), and CD45.2 (104); APC-Alexa750conjugated anti-CD3 (17A2); Alexa... and transcription factors (2). In mice, TGF- is required for the generation of both Th17 and T reg cells. The switch... , a population that is not able to induce inflammation in mice (13). ... |
|||
|
Source: Ecole Polytechnique, Centre de mathématiques |
|||
|
Collection: Mathematics |
|||
| 63 | Despite Increased CD4 Foxp3 Cells within the Infection Site, BALB/c IL-4 Receptor-Deficient Mice Reveal | ||
|
Summary: Despite Increased CD4 Foxp3 Cells within the Infection Site, BALB/c IL-4 Receptor-Deficient Mice... receptor- deficient BALB/c mice reveal differences in susceptibility to Leishmania major parasite... ,2 * Kathryn M. Jones,* Charles F. Anderson, and Nancy Noben-Trauth3 * BALB/c IL-4R / ... |
|||
|
Source: Arnold, Jonathan - Nanoscale Science and Engineering Center & Department of Genetics, University of Georgia |
|||
|
Collection: Biotechnology |
|||
| 64 | Activated/effector CD4+ T cells exacerbate acute damage in the | ||
|
Summary: up to 2 h after the injury. C57BL/6 mice were treated with CsA 2 h before, at the time of or 2 h... and TNF-receptor-deficient mutant mice (Scherbel et al., 1999). These studies demonstrated... injury (ACI) sites of C57BL/6 wild type and RAG1À / À immunodeficient ... |
|||
|
Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison |
|||
|
Collection: Biology and Medicine |
|||
| 65 | Ligand Selectivity and Gene Regulation by the Human Aryl Hydrocarbon Receptor in Transgenic MiceS | ||
|
Summary: the expression of a number genes, including CYP1A1, CYP1A2, CYP1B1, glutathione transferase Ya, UDP... relative inducibility of the AHR responsive genes Cyp1a1, Cyp1a2, and Cyp1b1 when expressed on an Ahr... , Held GA, and Diliberto JJ (1999) Adverse reproductive outcomes in the transgenic Ah ... |
|||
|
Source: Perdew, Gary - Department of Veterinary and Biomedical Sciences, Pennsylvania State University |
|||
|
Collection: Biology and Medicine |
|||
| 66 | Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella | ||
|
Summary: , Montreal, Quebec, Canada H3A 2T5. Summary Host resistance against Salmonella enterica serovar Typhimurium... to be a conserved host defence mechanism as IL-12 receptor-deficient humans are also immunocom- promised and highly... ). Nramp1 is critical to host defence, as mice lacking Nramp1 fail to control ... |
|||
|
Source: Littman, Dan - Skirball Institute of Biomolecular Medicine & Department of Microbiology, New York University |
|||
|
Collection: Biology and Medicine |
|||
| 67 | A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord | ||
|
Summary: - releasing peptide receptor-deficient mice. Proc. Natl Acad. Sci. USA 95, 31883192 (1998). 28. Chen, Z. F... of the dorsal spinal cord. GRPR mutant mice showed comparable thermal, mechanical, inflammatory and neuropathic... pain responses relative to wild-type mice. In contrast, induction of scratching ... |
|||
|
Source: Steinbach, Joe Henry - Washington University Pain Center & Department of Anesthesiology, Washington University in St. Louis |
|||
|
Collection: Biology and Medicine |
|||
| 68 | Summary and concluding remarks Summary and concluding remarks | ||
|
Summary: of ABCB4 deficient bone marrow into the LDL receptor deficient (LDLr KO) mice. Systemic disruption of ABCB... 4 in mice results in a virtual absence of phospholipids in bile and a strongly impaired biliary... cholesterol levels were significantly lower in mice reconstituted with ABCB4 ... |
|||
|
Source: van den Brink, Jeroen - Leiden Institute of Physics, Universiteit Leiden |
|||
|
Collection: Physics |
|||
| 69 | Exacerbation of Dopaminergic Terminal Damage in a Mouse Model of Parkinson's Disease by the G-Protein-Coupled | ||
|
Summary: and gliosis. After MPTP injection, PAR1 / mice showed significantly higher residual levels of dopamine, dopa... - mine transporter, and tyrosine hydroxylase and diminished mi- crogliosis compared with wild-type mice... inflammation are neuroprotective in the MPTP model of Parkinson's disease in mice (Rousselet et al., 2002; Wu |
|||
|
Source: Traynelis, Stephen F. - Department of Pharmacology, Emory University |
|||
|
Collection: Biology and Medicine |
|||
| 70 | European Archives of Paediatric Dentistry // 9 (1). 2008 Of mice and mutations | ||
|
Summary: with that of dia- betic leptin-deficient (ob/ob) and diabetic leptin receptor- deficient (db/db) mice used... 37 European Archives of Paediatric Dentistry // 9 (1). 2008 RESEARCH Of mice and mutations... : Phenotypic effects of the diabetic db/db and ob/ob mutations on the skull and teeth of ... |
|||
|
Source: Polly, David - Department of Geological Sciences, Indiana UniversityBloomington |
|||
|
Collection: Environmental Sciences and Ecology ; Biology and Medicine |
|||
| 71 | INFECTION AND IMMUNITY, 0019-9567/02/$04.00 0 DOI: 10.1128/IAI.70.1.416418.2002 | ||
|
Summary: - gamma receptor-deficient mice. J. Immunol. 158:52975304. 5. Dalrymple, S. A., L. L. Lucian, R. Slattery... by macrophages in response to heat-killed Listeria monocytogenes, STK-deficient mice exhibit increased... (19, 29). Furthermore, mice with a targeted deletion in exon 1 of the gene encoding STK are ... |
|||
|
Source: Correll, Pamela H. - Department of Veterinary and Biomedical Sciences, Pennsylvania State University |
|||
|
Collection: Biology and Medicine |
|||
| 72 | Deletion of Interleukin-12p40 Suppresses Autoimmune Cholangitis in Dominant Negative Transforming Growth | ||
|
Summary: , Alderuccio F, Hertzog P, Toh BH. GM-CSF-induced autoim- mune gastritis in interferon alpha receptor deficient... Growth Factor Receptor Type II Mice Katsunori Yoshida,1 Guo-Xiang Yang,1 Weici Zhang,1 Masanobu Tsuda,1... Ian R. Mackay,6 and M. Eric Gershwin1 Our laboratory has reported that mice that express ... |
|||
|
Source: Lian, Zhe-Xiong - School of Life Sciences, University of Science and Technology of China |
|||
|
Collection: Biology and Medicine |
|||
| 73 | Journal of Steroid Biochemistry & Molecular Biology 114 (2009) 161166 Contents lists available at ScienceDirect | ||
|
Summary: balance functions in vitamin D receptor deficient (VDR-/-) mice, an animal model of vitamin D... .elsevier.com/locate/jsbmb Vestibular dysfunction in vitamin D receptor mutant mice Anna Minasyana, , Tiina Keisalaa , Jing Zoub , Ya... -dependent rickets type II, and in 1 -hydroxylase deficient (1 -OHase-/-) ... |
|||
|
Source: Kalueff, Allan V. - Department of Pharmacology, Tulane University |
|||
|
Collection: Biology and Medicine |
|||
| 74 | NATURE MEDICINE VOLUME 8 NUMBER 11 NOVEMBER 2002 1235 Macrophages are essential cellular com- | ||
|
Summary: receptor-deficient mice. J. Clin. Invest. 101, 353363 (1998). 22. Cushing, S.D. et al. Minimally modified... endothelium accel- erates early atherosclerosis in LDL receptor-deficient mice. Arteriosler. Thromb. Vasc... for re- verse cholesterol transport. However, the observation that hy- percholesterolemic ... |
|||
|
Source: Gleeson, Joseph G. - Department of Neurosciences, University of California at San Diego |
|||
|
Collection: Biology and Medicine |
|||
| 75 | ISSN: 1524-4636 Copyright 2008 American Heart Association. All rights reserved. Print ISSN: 1079-5642. Online | ||
|
Summary: in another model of early atherogenesis, we undertook a similar study in the LDL receptor-deficient model... in Asm / versus Asm / mice on the Apoe / and Ldlr / backgrounds. Asm / ;Apoe / mice had a 40% to 50... % decrease in early foam cell aortic root lesion area compared with Asm / ;Apoe / mice (P 0.05) ... |
|||
|
Source: Tabas, Ira - Department of Physiology and Cellular Biophysics, Columbia University |
|||
|
Collection: Biology and Medicine |
|||
| 76 | Psychopharmacology (2004) 176: 386397 DOI 10.1007/s00213-004-1896-5 | ||
|
Summary: of CRF in these processes, we examined several ethanol (EtOH) related behaviors in mice that carry... transgenic (TG) and non- transgenic (non-TG) mice. In addition, because prelimin- ary results indicated... -sectional and longitudinal evaluation of this trait at two ages (100 and 200 days old). Results: We found that TG mice |
|||
|
Source: Ober, Carole - Committee on Genetics & Department of Human Genetics, University of Chicago |
|||
|
Collection: Biology and Medicine |
|||
| 77 | Cutting Edge: Organogenesis of Nasal-Associated Lymphoid Tissue (NALT) Occurs Independently of | ||
|
Summary: ), IL-7R / (7), and various chemokine/chemo- kine receptor-deficient mice (8). ROR and IL-7 have been... ) . Furthermore, using mice deficient in the retinoic acid receptor- related orphan receptor- , we found that NALT... similar to that of LT / mice. These include retinoic acid receptor-related orphan ... |
|||
|
Source: Littman, Dan - Skirball Institute of Biomolecular Medicine & Department of Microbiology, New York University |
|||
|
Collection: Biology and Medicine |
|||
| 78 | Induction of Progestin Receptors by Estradiol in the Forebrain of Estrogen Receptor-Gene-Disrupted Mice | ||
|
Summary: ) Estrogen inhibits the vascular injury response in estrogen receptor- deficient mice. Nat Med 3:545548. Ing... -Disrupted Mice C. A. Moffatt,1 E. F. Rissman,2 M. A. Shupnik,3 and J. D. Blaustein1 1Neuroscience and Behavior... , and Departments of 2Biology and 3Internal Medicine, University of Virginia, ... |
|||
|
Source: Blaustein, Jeffrey D. - Center for Neuroendocrine Studies, University of Massachusetts at Amherst |
|||
|
Collection: Biology and Medicine |
|||
| 79 | Conserved genomic structure of the Cyp1a1 and Cyp1a2 loci and their dioxin responsive elements cluster | ||
|
Summary: structures in aryl hydrocarbon receptor-deficient mice. Proc Natl Acad Sci U S A 2000;97:104427. [22] Bunger... Review Conserved genomic structure of the Cyp1a1 and Cyp1a2 loci and their dioxin responsive... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ... |
|||
|
Source: Bradfield, Christopher A. - McArdle Laboratory for Cancer , University of Wisconsin at Madison |
|||
|
Collection: Biology and Medicine |
|||
| 80 | Positive Regulatory Control Loop between Gut Leptin and Intestinal GLUT2/GLUT5 Transporters Links to | ||
|
Summary: of leptin. We next used AMPKa2 knockout (AMPKa22/2) mice to further study the role of a2 subunit of AMPK... are dependent upon leptin receptor, consistent with our previous data using leptin-receptor deficient fa/fa rats... the activity/expression of sugar transporters in the small ... |
|||
|
Source: Ecole Polytechnique, Centre de mathématiques |
|||
|
Collection: Mathematics |
|||
| 81 | Leading Edge Macrophages in the Pathogenesis | ||
|
Summary: modifications, including oxidation and hydrolysis by secretory phospholipase A2 (sPLA2) and secretory... of oxidized phosphatidylserine on the surface of apoptotic cells by phospholipase A2 (PLA2), which is a ligand... atherogenesis. Mice whose monocyte progenitor cells have defective ... |
|||
|
Source: Tabas, Ira - Department of Physiology and Cellular Biophysics, Columbia University |
|||
|
Collection: Biology and Medicine |
|||
| 82 | IMMUNOBIOLOGY Lack of antigen-specific tissue remodeling in mice deficient in the macrophage | ||
|
Summary: , Zheng NY, Clavijo M, et al. Normal host defense during systemic candidiasis in mannose receptor-deficient... IMMUNOBIOLOGY Lack of antigen-specific tissue remodeling in mice deficient in the macrophage... ), which were recently named CD301, have 2 homologues in mice: MGL1 and MGL2. MGLs are expressed on mac |
|||
|
Source: Hedrick, Stephen M. - Division of Biological Sciences, University of California at San Diego |
|||
|
Collection: Biology and Medicine |
|||
| 83 | Mice genetically deficient in neuromedin U receptor 2, but not neuromedin U receptor 1, have impaired nociceptive responses | ||
|
Summary: of two separate NMU receptor-deficient mice. (A and B) Schematic drawings depicting the genomic regions... of the NMU receptors-deficient mice to thermal tests. (A and C) No difference was observed in the tail flick... Mice genetically deficient in neuromedin U receptor 2, but not ... |
|||
|
Source: Steinbach, Joe Henry - Washington University Pain Center & Department of Anesthesiology, Washington University in St. Louis |
|||
|
Collection: Biology and Medicine |
|||
| 84 | Evidence for an Aryl Hydrocarbon Receptor-Mediated Cytochrome P450 Autoregulatory Pathway | ||
|
Summary: of cytochromes P450 1A1, 1A2, or 1B1 reduced AhR-mediated luciferase reporter activity, whereas cytochrome P450 2... of the xenobiotic-metabolizing en- zyme cytochrome P450 1A2, along with a complete loss of cytochrome P450 1A1... 450 isoforms 1A1, 1A2, 1B1, and 2E1 ... |
|||
|
Source: Omiecinski, Curtis - Department of Veterinary and Biomedical Sciences, Pennsylvania State University; Perdew, Gary - Department of Veterinary and Biomedical Sciences, Pennsylvania State University |
|||
|
Collection: Biology and Medicine |
|||
| 85 | non-adherent cells were plated (1 105 ) and cultured for 6 days. Unactivated | ||
|
Summary: -infected IFN-g receptor-deficient mice. J. Immunol. 158, 52975304 (1997). 14. DiTirro, J. et al. Disruption... 102 CD3 (µg ml1) CD3 (µg ml1) NDNDND IL-2(pgml1) +/+ / 16 8 4 12 0 10 Con A2 CD3 (µg ml1) +CD28... development of Th2 cells in Stat4-deficient mice. Nature 382, ... |
|||
|
Source: Galan, Jorge E - Boyer Center for Molecular Medicine & Department of Cell Biology, Yale University |
|||
|
Collection: Biology and Medicine |
|||
| 86 | Vascular Biology, Atherosclerosis and Endothelium Biology Overexpression of Bcl-2 in Vascular Endothelium | ||
|
Summary: receptor-deficient mice. Pathobiol- ogy 2004, 71:261266 26. Shindo T, Kurihara H, Maemura K, Kurihara Y... and inhibition of phospholipase A2 activation.72,73 Possible molecular mechanisms for cellular protection in... and activation of phospholipase A2 in breast ... |
|||
|
Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison |
|||
|
Collection: Biology and Medicine |
|||
| 87 | CIRCULATIONAHA/2005/541854 [R1] Tilman B. Drueke, and Ziad A. Massy | ||
|
Summary: . HMG-CoA reductase inhibition reverses LCAT and LDL receptor deficiencies and improves HDL in rats... Nguyen Khoa, Nadya Mothu, Jesus Angulo, Ralf Westenfeld, deficient (apoE-/-) mice Sevelamer prevents... -enhanced atherosclerosis progression in apolipoprotein E deficient (apoE-/- ) mice Short title: ... |
|||
|
Source: Angulo,Jesús - Centre de Morphologie Mathématique, Ecole des Mines de Paris |
|||
|
Collection: Computer Technologies and Information Sciences |
|||
| 88 | Antisense Inhibition of 5-Hydroxytryptamine2a Receptor Induces an Antidepressant-Like Effect in Mice | ||
|
Summary: receptor deficiency showed less immobility in the Porsolt's forced swim test, a well established animal... - doxical that mianserin, a 5-HT2A/2C receptor antagonist with an antidepressant effect also elicits... level of 5-HT that may down-regulate the receptor. In contrast, mianserin, a ... |
|||
|
Source: Sibille, Etienne - Center for the Neural Basis of Cognition & Department of Psychiatry, University of Pittsburgh |
|||
|
Collection: Biology and Medicine |
|||
| 89 | Uremia Accelerates both Atherosclerosis and Arterial Calcification in Apolipoprotein E Knockout Mice | ||
|
Summary: one recent study that examined CRF-induced atheroscle- rosis in the LDL receptordeficient (LDLR... Mice Ziad A. Massy,*§ Ognen Ivanovski,* Thao Nguyen-Khoa,* Jesus Angulo, Dorota Szumilak,* Nadya Mothu... calcification of atheromatous lesions. CRF was induced in apolipoprotein E knockout (apoE / ) mice to study (1 |
|||
|
Source: Angulo,Jesús - Centre de Morphologie Mathématique, Ecole des Mines de Paris |
|||
|
Collection: Computer Technologies and Information Sciences |
|||
| 90 | Redundant and unique roles of retinol dehydrogenases in the mouse retina | ||
|
Summary: in the Eyes of RDH Knockout Mice. A2E, the major hydrophobic and cytotoxic component of lipofuscin, is formed... months (Fig. 5C). In the Rdh8 / Rdh12 / mice, A2E levels at 10 months were 5.7-fold higher than in age... higher than in age-matched WT ... |
|||
|
Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University |
|||
|
Collection: Biology and Medicine |
|||
| 91 | Essential Role for STAT5 Signaling in CD25 CD4 Regulatory T Cell Homeostasis and the Maintenance of | ||
|
Summary: . L. Weissman. 1997. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 89... . Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant... in the peripheral lymphoid tissues of healthy mice. Recent studies have shown ... |
|||
|
Source: Baltimore, David - Division of Biology, California Institute of Technology |
|||
|
Collection: Biotechnology ; Biology and Medicine |
|||
| 92 | Aryl-Hydrocarbon Receptor Activation Regulates Constitutive Androstane Receptor Levels in Murine | ||
|
Summary: . Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice... belong to phase I and II enzyme families involved in xenobiotic metabolism, principally Cyp1a1, Cyp1a2... . In an attempt to identify novel target genes, C57BL/6J mice were ... |
|||
|
Source: Omiecinski, Curtis - Department of Veterinary and Biomedical Sciences, Pennsylvania State University; Perdew, Gary - Department of Veterinary and Biomedical Sciences, Pennsylvania State University |
|||
|
Collection: Biology and Medicine |
|||
| 93 | A pharmacological analysis of mice with a targeted disruption of the serotonin transporter | ||
|
Summary: molecules. SERT -/- mice exhibit an 90% reduction in head twitches in response to the Htr2a/2c agonist... Head twitches DOI Htr2a/2c agonist NR Qu et al. 2005 NR No response; not assessed... . 1999 NR (F) Bouali et al. 2003 (M) WAY 100635 Htr1a antagonist NR NR Holmes et ... |
|||
|
Source: Andrews, Anne M. - Huck Institutes of the Life Sciences, Pennsylvania State University |
|||
|
Collection: Biology and Medicine |
|||
| 94 | Arterioscler Thromb Vasc Biol . Author manuscript Rexinoid bexarotene modulates triglyceride but not cholesterol | ||
|
Summary: S , Steffensen KR , Hansson GK , Angelin B , Gustafsson JA . Accumulation of foam cells in liver X receptor-deficient... -type and LXR / -deficient mice, we show here that bexarotene induces hypertriglyceridemia and activates hepatic... ; Dimerization ; Female ; Homeostasis ; Lipogenesis ; Liver ; metabolism ; Mice ; ... |
|||
|
Source: Ecole Polytechnique, Centre de mathématiques |
|||
|
Collection: Mathematics |
|||
| 95 | THE ACUTE INFLAMMATORY RESPONSE IN DIVERSE SHOCK STATES Carson C. Chow,* Gilles Clermont, | ||
|
Summary: of the acute inflammatory response in C57Bl/6 mice, using input from experimental data. We found that a single... insults. This model was able to predict a dose range of endotoxin at which mice would die despite having... oxide by-products in mice, for disparate initial insults involving bacterial lipo- polysaccharide (LPS |
|||
|
Source: Chow, Carson C.- Laboratory of Biological Modeling, NIDDK, NIH & Department of Mathematics, University of Pittsburgh |
|||
|
Collection: Biology and Medicine ; Mathematics |
|||
| 96 | The developing use of heterozygous mutant mouse models in brain | ||
|
Summary: ,24,32,33]. By contrast, Vmat2 (Slc18a2)+/À and Bdnf+/À mice are viable, display altered monoamine neurotransmission... transporters. Although knockout mice lacking 5-HT, dopamineor norepinephrinetransportersare widelyused... evidence that heterozygous mutant mice with reduced (but not ... |
|||
|
Source: Kalueff, Allan V. - Department of Pharmacology, Tulane University |
|||
|
Collection: Biology and Medicine |
|||
| 97 | Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors | ||
|
Summary: resembled that of the conventional global-knockout mice (that is, CB1 receptor deficiency in all somatic... in nociceptive neurons localized in the peripheral nervous system of mice, preserving its expression in the CNS... , and analyzed these genetically modified mice in preclinical ... |
|||
|
Source: Steinbach, Joe Henry - Washington University Pain Center & Department of Anesthesiology, Washington University in St. Louis |
|||
|
Collection: Biology and Medicine |
|||
| 98 | Rexinoid bexarotene modulates triglyceride but not cholesterol metabolism via gene-specific permissivity of the RXR/LXR heterodimer in the liver | ||
|
Summary: . Accumulation of foam cells in liver X receptor-deficient mice. Circulation. 2002;106:1147-1153. #12;FIGURE... -type and LXR/-deficient mice, we show here that bexarotene induces hypertriglyceridemia and activates hepatic... and apolipoprotein E20 . Using wild-type mice and mice deficient ... |
|||
|
Source: Ecole Polytechnique, Centre de mathématiques |
|||
|
Collection: Mathematics |
|||
| 99 | INFECTION AND IMMUNITY, July 1996, p. 28042807 Vol. 64, No. 7 0019-9567/96/$04.00 0 | ||
|
Summary: of interferon- receptor deficiency on experimental Staphylococcus aureus septicemia and arthritis. J. Immunol... infection, homozygously mutant mice lacking the ICAM-1 gene were exposed to Staphylococcus aureus. Within 6... . Despite the high level of mortality, ICAM-1 / mice developed less frequent and less ... |
|||
|
Source: Springer, Timothy A. - Immune Disease Institute & Department of Pathology, Harvard University |
|||
|
Collection: Biology and Medicine |
|||
| 100 | 2752 Gupta et al. J. Clin. Invest. | ||
|
Summary: in humoral immunity) of T cells (6, 20, 21). The availability of IFN- receptordeficient (i.e., IFN R 0) mice... -out Mice Sanjay Gupta,* Anne Marie Pablo,* Xian-cheng Jiang,* Nan Wang,* Alan R. Tall,* and Christian... . Since mice with a targeted disruption of the apoE gene (apoE 0 mice) ... |
|||
|
Source: Dworkin, Jonathan - Department of Microbiology, Columbia University; Schindler, Christian - Department of Microbiology, Columbia University |
|||
|
Collection: Biology and Medicine |
|||