| Sample search results for: abcc9-encoded nucleotide binding |
| 1 | Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains | ||
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Summary: Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains... (ATPase associated with various cellular activities) domains that are thought to bind nucleotide; the role... of nucleotide binding and hydrolysis in each of these four ... |
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Source: Vale, Ron - Department of Cellular and Molecular Pharmacology, University of California at San Francisco |
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Collection: Biology and Medicine |
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| 2 | Nucleotide binding and hydrolysis by GlcV Thermodynamics of the ATP hydrolysis cycle of GlcV, | ||
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Summary: Nucleotide binding and hydrolysis by GlcV 43 Thermodynamics of the ATP hydrolysis cycle of Glc... V, the Nucleotide Binding Domain of the Glucose ABC transporter of Sulfolobus solfataricus Monika G. Pretz, Sonja... structure with two membrane-spanning domains that form the transport channel and two cytosolic ... |
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Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 3 | Nucleotide-Mediated Conformational Changes of Monomeric Actin and Arp3 Studied by Molecular | ||
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Summary: 51) and changes in the width of the nucleotide binding cleft. However, the conforma- tions of ATP... in subdomain 4 to prevent polymeriza- tion.12 Variations in the nucleotide binding cleft also depend... on crystallization conditions. In most crystal structures of actin, the nucleotide ... |
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Source: Pollard, Thomas D.- Department of Molecular, Cellular and Developmental Biology, Yale University |
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Collection: Biology and Medicine |
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| 4 | Stuctural stability and domain organization Structural Stability of GlcV, the Nucleotide Binding | ||
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Summary: Stuctural stability and domain organization Structural Stability of GlcV, the Nucleotide Binding... . Structurally, GlcV is a two domain protein with an N-terminal nucleotide binding domain and a C... the ability to bind nucleotides and to dimerize. These data indicate ... |
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Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 5 | Nucleotide Free Crystal Structure ATPgS Bound Complex I | ||
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Summary: D of the nucleotide-free clamp loader (gray). This suggests that binding of ATP alone is not responsible for opening... 180° 180° 180° Nucleotide Free Crystal Structure ATPgS Bound Complex I ATPgS Bound Complex II... of the nucleotide-free and nucleotide bound crystal structures of the ... |
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Source: Kuriyan, John - Howard Hughes Medical Institute & Departments of Chemistry & Molecular and Cell Biology, University of California at Berkeley |
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Collection: Biology and Medicine ; Chemistry |
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| 6 | Biochem. J. (2004) 379, 235242 (Printed in Great Britain) 235 ACCELERATED PUBLICATION | ||
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Summary: nucleotide-binding effects on backbone dynamics and folding of the nucleotide-binding domain... ) involves major conformational rearrangements among the three cytoplasmic domains: actuator (A), nucleotide-binding... of nucleotide binding were not readily manifested on the global fold and ... |
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Source: Ikura, Mitsuhiko - Division of Molecular and Structural Biology, University of Toronto |
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Collection: Biotechnology ; Biology and Medicine |
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| 7 | Polymerization and Structure of Nucleotide-free Actin Filaments | ||
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Summary: , but does not coincide with, the vacated nucleotide binding site. The empty nucleotide binding site... and ability to bind rhodamine phalloidin. Although the nucleotide cleft is empty, these ®laments do not bind e... versus polymer concentration ... |
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Source: Pollard, Thomas D.- Department of Molecular, Cellular and Developmental Biology, Yale University |
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Collection: Biology and Medicine |
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| 8 | Subscriber access provided by YALE UNIV Biochemistry is published by the American Chemical Society. 1155 Sixteenth Street | ||
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Summary: and Nucleotide Binding Kinetics Enrique M. De La Cruz, and Thomas D. Pollard Biochemistry, 1995, 34 (16), 5452... : Stabilization by Sucrose and Nucleotide Binding Kinetics? Enrique M. De La Cruz and Thomas D. Pollard... to study the kinetics of nucleotide binding to ... |
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Source: Pollard, Thomas D.- Department of Molecular, Cellular and Developmental Biology, Yale University |
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Collection: Biology and Medicine |
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| 9 | J. Am. Chem. Soc. Supporting Information for World Wide Web Edition page S1 Rational Modification of a Selection Strategy Leads to | ||
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Summary: ). The DNA nucleotides are colored brown for the substrate- binding arms and green for the enzyme region. All... is maintained for all substrate nucleotides with the corresponding DNA binding arms, this substitution of DNA... enzyme region, likely due to a spurious nucleotide insertion by ... |
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Source: Silverman, Scott K. - Department of Chemistry, University of Illinois at Urbana-Champaign |
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Collection: Chemistry ; Biology and Medicine |
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| 10 | 2002 Oxford University Press Nucleic Acids Research, 2002, Vol. 30, No. 5 12551261 Nucleotides of transcription factor binding sites exert | ||
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Summary: to microarrays containing all possible central 3 bp triplet binding sites indicates that the nucleotides... the true binding site specifi- cities, since these methods rely upon the assumption that the nucleotides... by the transcription factor makes the assumption that the nucleotides of ... |
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Source: Bulyk, Martha L. - Division of Genetics, Brigham and Women's Hospital, Harvard University; Church, George M. - Wyss Institute for Biologically Inspired Engineering & Department of Genetics, Harvard University |
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Collection: Biology and Medicine ; Biotechnology |
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| 11 | Programming Research Group FINDING TRANSCRIPTION FACTOR BINDING SITES IN DNA | ||
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Summary: the binding sites) that captures the dependencies between di#11;erent nucleotide positions. The templates we... use are not modelled directly on the nucleotide sequences of the binding sites; instead, we work... of Training Sequences Given a set of nucleotide sequences which are known ... |
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Source: Martin, Ralph R. - School of Computer Science, University of Wales, Cardiff |
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Collection: Computer Technologies and Information Sciences |
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| 12 | Sepharose 4B or Toyopearl AF-650M | ||
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Summary: Immobilized at different positions for optimal fit in nucleotide binding pocket Immobilized nucleotides... for affinity chromatography One step purification of nucleotide binding proteins Affinity column NTP binding... Matrix Sepharose® 4B or Toyopearl AF-650M Linker ... |
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Source: Lebendiker, Mario - Wolfson Centre for Applied Structural Biology, Hebrew University of Jerusalem |
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Collection: Biotechnology ; Biology and Medicine |
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| 13 | Running title: Interaction of aIF2 with tRNAi New insights into the interactions of the translation initiation factor 2 from | ||
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Summary: that the factor binds tRNAi and that nucleotide-dependent tRNAi binding requires at least the aIF2-dimer 5... found in EF-Tu or eEF1A 9 10 11 . The first domain (G domain) contains the guanine nucleotide-binding... . In spite of excess of Gpp(NH)p, only GDP molecules were found in the ... |
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Source: Manstein, Dietmar J. - Department of Biophysical Chemistry, Medizinische Hochschule Hannover |
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Collection: Biology and Medicine |
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| 14 | Journal of the Korean Physical Society, Vol. 53, No. 3, September 2008, pp. 1726$1730 How the Load and the Nucleotide State Aect the Actin | ||
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Summary: and the Nucleotide State Aect the Actin Filament Binding Mode of the Molecular Motor Myosin V Sergey V. Mikhailenko... found that in both the nucleotide-free and ADP-bound states single- and double-headed binding occurs... characterized the binding mode of myosin to actin in two ... |
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Source: Ishiwata, Shin'ichi - Department of Physics, Waseda University; Kinosita Jr., Kazuhiko - Department of Physics, Waseda University |
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Collection: Biology and Medicine ; Physics |
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| 15 | Identification by Site-directed Mutagenesis of Three Arginines | ||
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Summary: That Are Essential for Nucleotide Binding and Inhibition* (Received for publication, July 7, 1997, and in revised... nucleotides, which bind to the protein and allosterically inhibit fatty acid-induced proton trans- port... , and reconstituted into liposomes. We studied nucleotide ... |
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Source: Garlid, Keith - Department of Biology, Portland State University |
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Collection: Biology and Medicine |
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| 16 | Biochemistry 1994,33, 14565-14578 14565 Kinetic Mechanism of Adenine Nucleotide Binding to and Hydrolysis by the | ||
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Summary: Biochemistry 1994,33, 14565-14578 14565 Kinetic Mechanism of Adenine Nucleotide Binding... nucleotides, we have investigated the kinetic mechanism of adenine nucleotide binding to the Rep monomer... not significantly change the intrinsic tryptophan fluorescence, the ... |
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Source: Cistola, David P. - Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis; Lohman, Timothy M. - Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 17 | 10.1261/rna.517307Access the most recent version at doi: 2007 13: 899-911; originally published online Apr 16, 2007;RNA | ||
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Summary: RNA binding to the sRNP utilizes nucleotides beyond that RNA sequence hydrogen bonded to the s... RNA-guided nucleotide 2'- Structural features of the guide:target RNA duplex required for References http... features of the guide:target RNA duplex required for archaeal box C/D sRNA-guided nucleotide 29-O |
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Source: Maxwell, E. Stuart - Department of Molecular and Structural Biochemistry, North Carolina State University |
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Collection: Biology and Medicine |
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| 18 | Characterization of the ATP-Binding Domain of the Sarco(endo)plasmic Reticulum -ATPase: Probing Nucleotide Binding by Multidimensional NMR | ||
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Summary: : Probing Nucleotide Binding by Multidimensional NMR Mona Abu-Abed, Tapas K. Mal,§ Masatsune Kainosho... cycle catalyzed by SERCA1a, we have studied the ATP-binding domain of SERCA1a in both nucleotide... containing the nucleotide-binding domain of SERCA1a spanning residues ... |
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Source: Ikura, Mitsuhiko - Division of Molecular and Structural Biology, University of Toronto |
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Collection: Biotechnology ; Biology and Medicine |
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| 19 | Transcription The Flow of Information from the DNA to Protein Products Involves Both the processes | ||
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Summary: and Termination Once the Polymerase Binds to the Promoter, it Catalyzes _______________ The First Nucleotide... Nucleotide Bases Encode _________________ In the 1960s Sidney Brenner Hypothesised _________________Would... These ________________ Nucleotides from the Sequence This Changes the _______________ ... |
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Source: Cutler, Chris - Department of Biology, Georgia Southern University |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 20 | Binding specificity and mRNA targets of a C. elegans PUF protein, FBF-1 | ||
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Summary: nucleotides that are essential for FBF-1 binding. The binding elements comprise a "core" central region... . These data reveal nucleotides that are critical for FBF-1 binding, and provide a molecular explanation... . The core binding element To identify ... |
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Source: Wickens, Marv - Department of Biochemistry, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 21 | Functional Requirements for Specific Ligand Recognition by a Biotin-Binding RNA Charles Wilson,* Jay Nix, and Jack Szostak | ||
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Summary: aptamers, unpaired nucleotides make up a small fraction of the binding motif. Instead, the identity of 14... for BB8-5 is shown in Figure 1. Mapping the Functional Domain. Nucleotides responsible for biotin binding... to identify nucleotides that were highly conserved (thus involved in ... |
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Source: Szostak, Jack W. - Department of Genetics, Harvard University |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 22 | Real-time NMR Study of Three Small GTPases Reveals That | ||
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Summary: for nucleotide binding and hydrolysis. Fluorescently labeled guanine nucleotides, such as 2 (3 )-O... -Methylanthraniloyl)-tagged Nucleotides Alter Hydrolysis and Exchange Kinetics*S Received for publication,September 10, 2009... pathways through a conserved "switch" mechanism, which is turned on by ... |
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Source: Ikura, Mitsuhiko - Division of Molecular and Structural Biology, University of Toronto |
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Collection: Biotechnology ; Biology and Medicine |
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| 23 | Structural basis for cross-resistance to ribosomal PTC antibiotics | ||
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Summary: is determined by nucleotides residing remote from the PTC and, hence, are less conserved; pleuromutilins binding... pocket, and that nucleotide U2504 appears to meditate conformational rearrangements at its binding... surroundings offer various nucleotides for anti- biotics ... |
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Source: Martin, Jan M.L. - Department of Organic Chemistry, Weizmann Institute of Science |
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Collection: Chemistry |
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| 24 | nature structural biology . volume 5 number 6 . june 1998 Tubulin and FtsZ form a distinct family of | ||
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Summary: that common residues localize on the nucleotide-binding site and a region that interacts with the nucleotide... with motor proteins are, however, different. The highly conserved nucleotide-binding sites of tubulin and Fts... making lateral contacts either by the nucleotide-binding side or by the second ... |
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Source: structure and motility & Molecular Machines. |
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Collection: Biology and Medicine |
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| 25 | Crystal structures of actin-related protein 2 3 complex with bound ATP or ADP | ||
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Summary: . These struc- tures provide the an opportunity to compare all nucleotide-binding states in an actin... -actin (35). Nucleotide-dependent changes in subunit structure allow actin-binding proteins to distinguish... ). Arp3 binds ATP, but appreciable hydrolysis of the nucleotide by this ... |
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Source: Pollard, Thomas D.- Department of Molecular, Cellular and Developmental Biology, Yale University |
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Collection: Biology and Medicine |
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| 26 | A Statistical Model for Investigating Binding Probabilities of DNA Nucleotide Sequences Using Microarrays | ||
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Summary: A Statistical Model for Investigating Binding Probabilities of DNA Nucleotide Sequences Using... -up investigation, Bulyk, Johnson and Church (2002) studied the interdependence of nucleotides on the binding... of nucleotides in the binding affinities of transcription ... |
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Source: Bulyk, Martha L. - Division of Genetics, Brigham and Women's Hospital, Harvard University; Church, George M. - Wyss Institute for Biologically Inspired Engineering & Department of Genetics, Harvard University |
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Collection: Biology and Medicine ; Biotechnology |
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| 27 | Be'ware of genomic nucleotide composition while hunting transcription factor binding sites in ChIP-based experiments | ||
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Summary: Be'ware of genomic nucleotide composition while hunting transcription factor binding sites in Ch... recognize and bind to short sequences of DNA (TF binding sites TFBS). ChIP-based experiments, such as Ch... IP-Seq, are commonly used to isolate sequences that TFs putatively bind within. ... |
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Source: Sahinalp, S. Cenk - School of Computing Science, Simon Fraser University |
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Collection: Biology and Medicine ; Computer Technologies and Information Sciences |
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| 28 | Nucleotide Specificity versus Complex Heterogeneity in Exonuclease Activity Measurements | ||
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Summary: Nucleotide Specificity versus Complex Heterogeneity in Exonuclease Activity Measurements Jo... activity is nucleotide-dependent, and that a fluorescent label bound to a nucleotide significantly slows... are fluorescently labeled at two specific sites in the nucleotide sequence (positions 5 and 38 from the ... |
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Source: Enderlein, Jörg - Forschungszentrum Jülich |
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Collection: Chemistry |
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| 29 | Spectroscopic investigation of the reaction mechanism of CopB-B, the catalytic fragment from an archaeal | ||
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Summary: , such as nucleotide binding (N), phosphorylation (P), actuator (A) and heavy metal binding (HMA) domains. During... state, with high binding affinity for the substrates (ions and nucleotides) on one side of the membrane... . The catalytic fragment, named CopB-B, comprises the ... |
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Source: Gerwert, Klaus - Fakultät für Biologie, Ruhr-Universität Bochum |
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Collection: Biology and Medicine |
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| 30 | Molecular Cell 23, 913923, September 15, 2006 2006 Elsevier Inc. DOI 10.1016/j.molcel.2006.07.020 Large Conformational Changes in a Kinesin | ||
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Summary: nucleotide upon inter- action with microtubules (MTs), then bind and hydro- lyze ATP to move along the MT... in the empty motor, including melt- ing of the switch II helix a4, closure of the nucleotide binding pocket... head bound to ADP, no nucleotide, or an ATP an- alog ... |
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Source: Endow, Sharyn - Department of Cell Biology, Duke University; MRC, Laboratory of Molecular Biology, Microtubules: structure and motility & Molecular Machines.; Richardson, David - Department of Biochemistry, Duke University |
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Collection: Biology and Medicine ; Biotechnology |
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| 31 | http://jbx.sagepub.com Journal of Biomolecular Screening | ||
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Summary: of LARG-Stimulated RhoA Nucleotide Binding via a Novel Fluorescence Polarization Assay CHRIS R. EVELYN,1... fluorescence polarization guanine nucleotide-binding assay using BODIPYTexas RedGTPS (BODIPY... A nucleotide binding. Five compounds identified from the high-throughput screen ... |
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Source: Sondek, John - Departments of Pharmacology & Biochemistry and Biophysics, University of North Carolina at Chapel Hill |
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Collection: Biology and Medicine |
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| 32 | Theories about the origin of the genetic code require specific recognition between nucleic acids and amino | ||
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Summary: If one or more of the stereochemical hypotheses were true, nucleotides at arginine-binding sites would... nucleotides into `binding site' and `nonbinding site' classes and into `motif' and `nonmotif' classes... , depending on whether they are present in the ligand-binding site or in a ... |
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Source: Knight, Rob - Department of Chemistry and Biochemistry, University of Colorado at Boulder |
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Collection: Environmental Sciences and Ecology ; Biotechnology ; Biology and Medicine |
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| 33 | Functional Analysis of Cdc42 Residues Required for Guanine Nucleotide Exchange* | ||
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Summary: ) is impaired in nucleotide binding and consequently binds Dbs with higher affinity than wild-type Cdc42... regions to disorganize the nucleotide binding pocket and directly occlude the Mg2 bind- ing site. As we... the nucleotide ... |
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Source: Sondek, John - Departments of Pharmacology & Biochemistry and Biophysics, University of North Carolina at Chapel Hill |
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Collection: Biology and Medicine |
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| 34 | Nucleotides influence the SecE conformation at the contact surface of the SecYEG dimer | ||
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Summary: presented here suggest the presence of a nucleotide binding site on SecYEG. Walker A and B motives... are common for nucleotide binding proteins [211] but there is no evidence for such motifs in the amino acid... sequences of the SecYEG subunits. On the other hand, other proteins are known to ... |
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Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 35 | J. Mol. Biol. Supplementary Material page S1 Optimization and Generality of a Small Deoxyribozyme that Ligates RNA | ||
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Summary: nucleotides surrounding the ligation junction (UAUAGGAA) were systematically altered and the effects... of the deoxyribozyme, including maintaining its substrate binding arms. The results of these initial ligation assays... of experiments to analyze changes to RNA substrate nucleotides and their effects on ligation by the 7Q10 |
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Source: Silverman, Scott K. - Department of Chemistry, University of Illinois at Urbana-Champaign |
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Collection: Chemistry ; Biology and Medicine |
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| 36 | Dynamics of Nucleotides in VDAC Channels: Structure-Specific Noise Generation | ||
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Summary: ;Evidence for a nucleotide binding site within the channel lumen The apparent ability of the channel... a binding site for the nucleotide. If indeed the level of current noise depends on the ability... of the nucleotide molecule to bind to a site inside the channel, ... |
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Source: Bezrukov, Sergey M. - Laboratory of Physical and Structural Biology, National Institute of Child Health and Human Development |
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Collection: Chemistry ; Biology and Medicine |
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| 37 | Biochemistry 1988, 27, 1205-1212 1205 Ogata, R. T., & Gilbert, W. (1979) J. Mol. Biol. 132, 709. | ||
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Summary: DNA binding affinity by nucleotide cofactors to include those nucleotides having significant concentrations... that prevent hydrolysis but not nucleotide binding. Weinstock et al. (1981) have reported that in the presence... of these nucleotides is the ... |
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Source: Kowalczykowski, Stephen C. - Section of Microbiology, University of California, Davis |
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Collection: Biology and Medicine |
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| 38 | Polar Destabilization of DNA Duplexes with Single-Stranded Overhangs by the Deinococcus radiodurans SSB Protein | ||
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Summary: it to bind to single-strand extensions shorter than 26-30 nucleotides. The capacity to displace the shorter... DrSSB Protein Binds 15-Nucleotide DNA Extensions Adjacent to Duplex DNA. In an effort to examine... SSB protein binds efficiently and shifts the unannealed ... |
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Source: Cox, Michael M. - Department of Biochemistry, University of Wisconsin at Madison; Lohman, Timothy M. - Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 39 | Nucleic Acids Research Supplementary Material page S1 Structure-Function Correlations Derived from | ||
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Summary: was prepared with its 40-nucleotide DNA enzyme region subjected to 25% randomization at each position relative... the distribution of nucleotide changes per molecule relative to the parent sequence as a function of the fraction... parent nucleotide at each position. Let x = fraction "correct" nucleotide at ... |
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Source: Silverman, Scott K. - Department of Chemistry, University of Illinois at Urbana-Champaign |
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Collection: Chemistry ; Biology and Medicine |
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| 40 | Pre-Steady-State Kinetic Studies of the Fidelity and Mechanism of Polymerization Catalyzed by Truncated Human DNA Polymerase | ||
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Summary: residues involved in nucleotide and DNA binding and catalysis (10-13). Thus, tPol allowed us to estimate... Equilibrium of Nucleotide Binding. The kinetic mechanism of single-nucleotide incorporation into a synthetic... ,DNAn) binds an incoming ... |
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Source: Suo, Zucai - Department of Biochemistry, Ohio State University |
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Collection: Biology and Medicine |
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| 41 | Rapid Irreversible G Protein Alpha Subunit Misfolding Due to Intramolecular Kinetic Bottleneck that Precedes Mg2+ | ||
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Summary: with protective but weak preequilibrium nucleotide binding at micromolar ambient GTPS concentrations. Because... concentrations 10-100 times higher than those commonly employed in G protein radio-nucleotide binding studies... . High background noise due to nonspecific binding of excess ... |
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Source: Sharp, Kim - Department of Biochemistry and Biophysics, University of Pennsylvania |
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Collection: Biology and Medicine ; Chemistry |
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| 42 | Effective species count and motif efficiency: The value of comparative genomics in characterizing conserved sequence positions | ||
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Summary: for constructing a nucleotide equilibrium probability dis- tribution for each multiply aligned DNA sequence... 12208-3425, USA. a nucleotide equilibrium probability distribution that is dom- inated by a pair... of nucleotides. In our analysis of phyloge- netic trees from the literature, we find that for a phylogenetic tree |
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Source: Bystroff, Chris - Department of Biology, Rensselaer Polytechnic Institute |
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Collection: Biotechnology ; Biology and Medicine |
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| 43 | Saccharomyces cereVisiae Replication Protein A Binds to Single-Stranded DNA in Multiple Salt-Dependent Modes | ||
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Summary: . Measurements of the Hobsd for scRPA binding to (dT)L at 1.5 M NaCl yield a contact site size of 28 nucleotides... nucleotides), stabilized at low [NaCl], in which only three of its oligonucleotide/oligosaccharide binding... with an occluded site size of 35 nucleotides) or all four ... |
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Source: Cistola, David P. - Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis; Lohman, Timothy M. - Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 44 | Induced nucleotide specificity in a GTPase Shu-ou Shan and Peter Walter | ||
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Summary: GTPases. Unlike canonical GTPases that bind guanine nucleotides tightly and require nucleotide exchange... , with GDP binding and dissociating quickly (1416). Therefore, there is no requirement for nucleotide... the hydrolysis of noncognate nucleotides such as XTP ... |
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Source: Walter, Peter - Department of Biochemistry and Biophysics, University of California at San Francisco |
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Collection: Biology and Medicine |
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| 45 | SUPPLEMENTARY MATERIALS Supplementary Figure 1: RNA-binding properties of fibrillar Hfq. Higher-order Hfq polymers | ||
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Summary: - nucleotide poly(A) tail. As discussed in the text, this RNA-binding activity suggests the in vivo relevance... SUPPLEMENTARY MATERIALS Supplementary Figure 1: RNA-binding properties of fibrillar Hfq. Higher... of RNA-binding, as indicated by electrophoretic mobility shift assays (EMSA) and shown in the gel ... |
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Source: Mura, Cameron - Department of Chemistry, University of Virginia |
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Collection: Chemistry |
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| 46 | Cell Communication Signaling Systems | ||
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Summary: as Transmembrane Proteins on Interacting Cells, or Bind the Extracellular Matrix 6) Others:- Including Nucleotides... the and subunits have _________________ in the Plasma Membrane The Guanine Nucleotide Binding Site (GTP... __________________ These Can be Produced by a Cell and Bind ... |
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Source: Cutler, Chris - Department of Biology, Georgia Southern University |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 47 | brane stalks (Fig. 4A). Moreover, the trimers are open, as would be predicted if the stalks | ||
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Summary: 2003 Closing of the Nucleotide Pocket of Kinesin-Family Motors upon Binding to Microtubules Nariman... spectroscopy to show that the nucleotide- binding site of kinesin-family motors closes when the motor... [heterotrimeric guanine nucleotidebinding proteins], explains the EPR data. ... |
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Source: Vale, Ron - Department of Cellular and Molecular Pharmacology, University of California at San Francisco |
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Collection: Biology and Medicine |
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| 48 | Mechanism for De Novo RNA Synthesis and Initiating Nucleotide Specificity by T7 RNA Polymerase | ||
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Summary: cycle where the RNA polymerase binds two nucleotides rather than a nascent RNA polymer and a single... , ATP, CTP or UTP to bind. The structures show that the initiating nucleotides bind RNA polymerase... transcription bubble, (3) initiating nucleotide ... |
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Source: Yin, Y. Whitney - Department of Chemistry and Biochemistry, University of Texas at Austin |
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Collection: Chemistry ; Biology and Medicine |
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| 49 | Combinatorial Chemistry & High Throughput Screening, 2003, 6, 79-99 1 1386-2073/03 $41.00+.00 2003 Bentham Science Publishers Ltd. | ||
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Summary: ] has been instrumental in revealing a universal mechanism for nucleotide binding, GTP #12... to monitor these events. Small GTPases bind guanine nucleotides in a structurally well-defined nucleotide-binding... pocket that uses a coordinated Mg2+ ion essential for ... |
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Source: Sondek, John - Departments of Pharmacology & Biochemistry and Biophysics, University of North Carolina at Chapel Hill |
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Collection: Biology and Medicine |
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| 50 | |Research Focus A new structural state of myosin | ||
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Summary: to actin filaments, but, when free of nucleotide, the motor binds tightly to actin, a state known as 'rigor... ' (Figure 1). Identi- fying the conformational changes induced by nucleotide binding to the motor... in the nucleotide-binding cleft or P-loop of the motor are not only expected ... |
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Source: Endow, Sharyn - Department of Cell Biology, Duke University |
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Collection: Biology and Medicine |
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| 51 | Induced-fit tightens pleuromutilins binding to ribosomes and remote | ||
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Summary: with ribosomal nucleotides. Among the conformational rearrangements of the rRNA ob- served upon binding of all... 2506 (Fig. 4a), a nucleotide playing a key role in pleuromutilin binding, thus showing that this L3... region is capable of interacting with PTC nucleotides involved in ... |
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Source: Martin, Jan M.L. - Department of Organic Chemistry, Weizmann Institute of Science |
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Collection: Chemistry |
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| 52 | OPTIMAL ALGORITHM FOR FINDING DNA MOTIFS WITH NUCLEOTIDE ADJACENT DEPENDENCY | ||
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Summary: that the occurrence of a nucleotide in a binding site is independent of other nucleotides. More complicated... at a particular position of a binding site is independent of the occurrence of nucleotides at other positions... .L.F. Johnson and G.M. Church. Nucleotides ... |
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Source: Chin, Francis Y.L. - Department of Computer Science, Hong Kong University |
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Collection: Computer Technologies and Information Sciences |
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| 53 | Supporting Information Wiley-VCH 2005 | ||
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Summary: and deoxyribozyme activity was assayed. Figure 2b shows the experiment in which all nucleotides of the binding arms... of lariat RNA, the DNA binding arms of the deoxyribozyme must bind with the appropriate nucleotides... and the lariat product (the RNA nucleotides ... |
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Source: Silverman, Scott K. - Department of Chemistry, University of Illinois at Urbana-Champaign |
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Collection: Chemistry ; Biology and Medicine |
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| 54 | Structural Features of the Noncatalytic cGMP Binding Sites of Frog Photoreceptor Phosphodiesterase Using cGMP Analogs* | ||
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Summary: activates cyclic nucleotide hydrolysis at the active site (7, 8). For PDE5, the noncatalytic cGMP binding... of interactions that stabi- lize the high affinity binding of cGMP to noncatalytic sites on PDE. Cyclic nucleotide... analogs have been successfully em- ployed to define the topology of the ... |
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Source: Cote, Rick H. - Department of Biochemistry and Molecular Biology, University of New Hampshire |
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Collection: Biology and Medicine |
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| 55 | pubs.acs.org/Biochemistry Published on Web 08/26/2010 r 2010 American Chemical Society 8266 Biochemistry 2010, 49, 82668275 | ||
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Summary: (nucleotide) for single-stranded M13 ssDNA (28). Fluorescence Titrations. Equilibrium binding of DrSSB protein... T)L is shorter than 35 nucleotides or longer than 60 nucleotides, the observed binding isotherms display two... SSB dimer. Assuming that the full occluded site size for ssDNA ... |
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Source: Cox, Michael M. - Department of Biochemistry, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 56 | The helicase-like domain from Thermotoga maritima reverse gyrase: catalytic cycle | ||
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Summary: ............................................................................................. 27 Stopped-flow nucleotide binding kinetics... ................................................................................................................ 48 The latch modulates nucleotide and DNA ... |
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Source: Amrhein, Valentin - Zoologisches Institut, Universität Basel |
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Collection: Environmental Sciences and Ecology |
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| 57 | An Exhaustive Search for the Inositol 1,4,5-triphosphate Receptor Protein in Keywords: proteins { plants { ITPR { IP3 { HMM { evolution { | ||
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Summary: in eukaryotes. In humans and other animals the protein ITPR forms a ligand gated Calcium-ion channel that binds... an ITPR protein homolog has not been identi#12;ed, neither has a protein with similar IP3 binding activity... . An exhaustive search for possible candidates with IP3 binding activity in plants has been performed. ... |
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Source: Sahinalp, S. Cenk - School of Computing Science, Simon Fraser University |
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Collection: Biology and Medicine ; Computer Technologies and Information Sciences |
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| 58 | ATP Binding Enables Broad Antibiotic Selectivity of Aminoglycoside Phosphotransferase(3)-IIIa | ||
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Summary: antibiotics. In this study, we use the Gaussian network model to investigate how the binding of nucleotides... to the nucleotideAPH complex is much smaller. The differential effects of nucleotide binding and antibiotic binding... of the enzyme. The surprising ... |
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Source: Ullmann, G. Matthias - Lehrstuhl Biopolymere, Universität Bayreuth |
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Collection: Biology and Medicine ; Chemistry |
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| 59 | Psoralen Photo-Cross-Linking by Triplex-Forming Oligonucleotides at Multiple Sites in the Human Rhodopsin Gene | ||
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Summary: to nine nucleotides in length. High-affinity binding was maintained with linkers of up to 10 nucleotides... with only a modest decrease in binding affinity. To test the ability of such nucleotide "linkers... and Binding Affinity of "Linker" TFOs. Two approaches were ... |
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Source: Wensel, Theodore G. - Department of Biochemistry and Molecular Biology, Baylor College of Medicine |
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Collection: Biology and Medicine |
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| 60 | Molecular Biology of the Cell Vol. 3, 1015-1024, September 1992 | ||
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Summary: . As such there are interesting parallels with other cellular proteins that bind and hydrolyze a specific nucleotide, either ATP... has been well characterized (Figure 1). Each actin molecule binds an adenine nucleotide in the cleft... binding proteins in catalytically accelerating the ... |
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Source: Pollard, Thomas D.- Department of Molecular, Cellular and Developmental Biology, Yale University |
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Collection: Biology and Medicine |
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| 61 | The case for a common ancestor: kinesin and myosin motor proteins and G proteins | ||
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Summary: and other phosphate-loop (P-loop) containing nucleotide-binding proteins. We demonstrate that kinesin... nucleotide-binding motif, and describe the likely topology of this ancestor. These proteins use similar... among the motor proteins kinesin and myosin, as well as among motor proteins and other nucleotide-binding |
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Source: Vale, Ron - Department of Cellular and Molecular Pharmacology, University of California at San Francisco |
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Collection: Biology and Medicine |
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| 62 | Chemical parameters influencing fine-tuning in the binding of macrolide antibiotics to the | ||
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Summary: of the macrolactone ring and highlighted the nucleotides of the 23S rRNA involved in the drugs' binding. It also... binding pocket and interacts mainly with nucleotides of domain V of the 23S rRNA. Its desosamine and cladi... 3.4 Å), a nucleotide that was found bio- chemically to be ... |
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Source: Martin, Jan M.L. - Department of Organic Chemistry, Weizmann Institute of Science |
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Collection: Chemistry |
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| 63 | Modeling DNA Interactions in Nucleosome Particles (A Computational Study of DNA Interactions in Nucleosome Particles) | ||
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Summary: substitutions of nucleotides on the Xenopus laevis nucleosome x-ray crystal structure, our model system... as a reference for subsequent nucleotide substitutions in our parameterized histone-DNA model. The magnitude... of energy differences resulting from the nucleotide substitutions will be presented in the context |
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Source: Kansas, University of - Information and Telecommunication Technology Center |
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Collection: Computer Technologies and Information Sciences ; Multidisciplinary Databases and Resources |
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| 64 | Protein Structure and Function I. Form follows function-review of protein structure | ||
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Summary: chemical binding a. small ligand binding sites b. protein binding sites: coiled coil movie c. molecular... . GTP-binding/hydrolysis induced allostery C. Phosphorylation induced allostery D. Putting concepts... to work: Crm1 binding of cargo and Ran Proteins come in all shapes and sizes ... |
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Source: Lycan, Deborah E. - Department of Biology, Lewis and Clark College |
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Collection: Biology and Medicine |
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| 65 | 5872 Biochemistry 1986, 25, 5872-5881 Michelson, A. M., Dondon, J., & Grunberg-Manago, M. | ||
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Summary: , 8-Azido-ATP: Determination of Nucleotide Cofactor Binding Parameters and of the Relationship between... -linking inhibition studies, the binding of other nucleotide cofactors to recA protein has also been studied... that the binding affinity of ade- nine-containing ... |
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Source: Kowalczykowski, Stephen C. - Section of Microbiology, University of California, Davis |
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Collection: Biology and Medicine |
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| 66 | THEJOURNALOF BIOLOGICALCHEMISTRY 0 1989by The American Society for Biochemistry nnd MolecularBiology,Inc. | ||
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Summary: -ADP, suggesting that oAMP inhibition occurs at the nucleotide binding site of the enzyme. The rate of inactivation... +-ATPaseactivity, suggesting that these lipids either aidin the formation of the nucleotide binding site or render... ). These studies also indicated that during nucleotide ... |
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Source: Wells, Jeffrey D. - Department of Biology, West Virginia University |
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Collection: Biology and Medicine |
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| 67 | X-ray Structures of the Signal Recognition Particle Receptor Reveal Targeting Cycle Intermediates | ||
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Summary: position the nucleotide into a non-catalytic conformation. The basis for the lower specificity of binding... Figure 3. Structural adaptations in the active site upon nucleotide binding. (A) Asp258 is shown... hydrolysis reported in nucleotide binding studies of FtsY ... |
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Source: Walter, Peter - Department of Biochemistry and Biophysics, University of California at San Francisco |
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Collection: Biology and Medicine |
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| 68 | G Proteins Regulate Dihydropyridine Binding to Moss Plasma Membranes* | ||
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Summary: commercial sources. RESULTS Effects of Guanine Nucleotides on DHP Binding--G proteins have been implicated... of the nucleotides GDP, cAMP, and ATP did not modify DHP binding (Tables I and II). However, the active G protein mod... the moss P. patens contain a single class of binding ... |
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Source: Schumaker, Karen - School of Plant Sciences, University of Arizona |
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Collection: Biology and Medicine |
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| 69 | JOURNAL OF VIROLOGY, May 2003, p. 55785588 Vol. 77, No. 10 0022-538X/03/$08.00 0 DOI: 10.1128/JVI.77.10.55785588.2003 | ||
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Summary: between nucleotides 23147 and 23405. The result showed that the potential K8 binding DNA sequence can... region (between nucleotides 22925 and 23635) were pre- pared and used in EMSAs. No specific binding... . AT palindromes are essential for KSHV ori-Lyt replication and K8 binding. (A) ... |
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Source: McQuade, D. Tyler - Department of Chemistry and Biochemistry, Florida State University |
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Collection: Chemistry |
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| 70 | Original article Functional interaction of calmodulin with a plant cyclic nucleotide | ||
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Summary: binding of cyclic nucleotide. These proteins have a cytoplasm-localized cyclic nucleotide binding domain... subunits have cyclic nucleotide binding domains (CNBDs); gating (ligand activation) occurs upon binding... protein; CaM, calmodulin; ... |
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Source: Zielinski, Ray - Department of Plant Biology, University of Illinois at Urbana-Champaign |
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Collection: Biotechnology |
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| 71 | Sequential 2 -O-Methylation of Archaeal Pre-tRNATrp Nucleotides | ||
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Summary: Sequential 2 -O-Methylation of Archaeal Pre-tRNATrp Nucleotides Is Guided by the Intron... -O-methyla- tion of nucleotides C34 and U39 followed by intron exci- sion. Positioning of the box C... proteins. With both kinetic studies and single nucleotide substitutions of target and guide nucleotides, we |
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Source: Maxwell, E. Stuart - Department of Molecular and Structural Biochemistry, North Carolina State University |
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Collection: Biology and Medicine |
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| 72 | Site Size of Cooperative Single-stranded RNA Binding by Poliovirus RNA-dependent RNA Polymerase* | ||
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Summary: , with each nucleotide contributing equal binding energy. Then, when the RNA oligonucleotide is long enough... / nucleotide of the protein-RNA interaction were to increase when the RNA-binding site was filled (Fig. 1B... protein. A, effect of oligonucleotide length on binding ... |
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Source: Kirkegaard, Karla - Department of Microbiology and Immunology, Stanford University |
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Collection: Biology and Medicine |
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| 73 | Proc. Natl. Acad. Sci. USA Vol. 94, pp. 88728877, August 1997 | ||
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Summary: the potentiatory action of MgADP involves the nucleotide-binding domains of SUR1. K-ATP channels are also activated... nucleotide-binding domains (NBDs) that contain highly conserved Walker A (WA) and Walker B (WB) con- sensus... , nucleotide-binding domain; K-ATP channel, ATP-sensitive potassium channel. 8872 ... |
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Source: Tucker, Stephen J. - Department of Physics, University of Oxford |
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Collection: Physics ; Biology and Medicine |
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| 74 | 11821191 Nucleic Acids Research, 2002, Vol. 30, No. 5 2002 Oxford University Press Protein and drug interactions in the minor groove of DNA | ||
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Summary: , and simultaneous binding to N3 and N2 in guanines is extremely rare. Contacts with two consecutive nucleotides... instances of Asn and Phe residues that bind to straight DNA, where there is binding to one nucleotide only... of TATA-box binding proteins. These Asn ... |
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Source: Schneider, Bohdan - Institute of Biotechnology (Prague) |
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Collection: Biotechnology ; Materials Science |
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| 75 | Structural basis for the interaction of antibiotics with the peptidyl | ||
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Summary: chloramphenicol and RNA nucleotides, two ions (Mg-C1 and Mg-C2) are involved in chlor- amphenicol binding. We... ), the pivotal nucleotide for lincosamide binding22 . Although the 2OH group is also less than 4.0 AÊ away from O... why this nucleotide is essential for macrolide ... |
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Source: Martin, Jan M.L. - Department of Organic Chemistry, Weizmann Institute of Science |
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Collection: Chemistry |
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| 76 | Automated ConstraintBased Nucleotide Sequence Selection | ||
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Summary: bind to analyze the thermal hybridization properties of extant nucleotide sequences. This initial... contained in bind to search a ``nucleotide space'' for sequences satisfying a set of prespecified design... of Cloning Vector =) scan Selection of Nucleotides for Template Context =) ... |
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Source: Gifford, David K. - Computer Science and Artificial Intelligence Laboratory & Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology (MIT) |
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Collection: Computer Technologies and Information Sciences ; Biotechnology |
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| 77 | Automated Constraint-Based Nucleotide Sequence Selection | ||
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Summary: a program named bind to analyze the thermal hybridization properties of extant nucleotide sequences... in bind to search a "nucleotide space" for sequences satisfying a set of pre-specified design constraints... permissive for non-specific binding, thereby allowing some ... |
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|
Source: Gifford, David K. - Computer Science and Artificial Intelligence Laboratory & Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology (MIT); Hartemink, Alexander - Center for Bioinformatics and Computational Biology & Department of Computer Science, Duke University |
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Collection: Biotechnology ; Computer Technologies and Information Sciences |
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| 78 | J. Mol. Biol. (1996) 262, 421436 RNA Sequence Determinants for Aminoglycoside | ||
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Summary: , caused by non-canonical base-pairs. Nucleotides that are important for binding of paromomycin were... the nucleotides in the decoding region. The A site is where aminoglycosides bind to the ribosome, as determined... ). The decoding region has been reduced to a small functional domain (64 ... |
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Source: Dahlquist, Kam D. - Biology Department, Loyola Marymount University |
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Collection: Biology and Medicine |
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| 79 | Crystal Structure of Mycobacterium tuberculosis D-3-Phosphoglycerate Dehydrogenase | ||
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Summary: . In addition to substrate and nucleotide-binding domains, they possess a homologous C-terminal domain that... . tuberculosis PGDH was attempted with the E. coli PGDH monomer or its nucleotide-binding domain (the largest... 98 and 283319), the nucleotide-binding do- main (residues 99282), the regulatory domain (residues 454 ... |
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|
Source: Kopan, Raphael - Department of Molecular Biology and Pharmacology, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 80 | PERSPECTIVE Guilt by association: The arginine case revisited | ||
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Summary: , of the nucleo- tides in binding sites, the fraction of nucleotides both in binding sites and in codons should... the fraction of nucleotides in codons is greater for nucleotides inside binding sites, in which case we assign... ); otherwise it is halved and subtracted ... |
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Source: Knight, Rob - Department of Chemistry and Biochemistry, University of Colorado at Boulder |
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Collection: Environmental Sciences and Ecology ; Biotechnology ; Biology and Medicine |
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| 81 | MOLECULAR AND CELLULAR BIOLOGY. JUIY 1989, p. 2944-2949 Vol. 9, No. 7 0270-7306/89/072944-06$02.00/0 | ||
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Summary: biology is to define the nucleotide sequences required for binding by a specific transcriptional... of oligonucleotides containing GCN4-binding sites. An oligonucleotide containing 23 nucleotides of random sequence DNA... the nucleotide sequence requirements for GCN4 ... |
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Source: |
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Collection: Biology and Medicine |
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| 82 | Chemo-Mechanical Coupling in F1-ATPase Revealed by Catalytic Site Occupancy during Catalysis | ||
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Summary: , but the third vacant site can bind a medium nucleotide weakly. INTRODUCTION F1-ATPase, a water-soluble portion... , whereas the other three a-b interfaces provide noncatalytic nucleotide binding sites (4). Nucleotide... resolved g subunit mostly contain two catalytic ... |
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Source: Ishiwata, Shin'ichi - Department of Physics, Waseda University |
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Collection: Physics ; Biology and Medicine |
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| 83 | Eur. J. Biochem. 128, 113-117(1982) Q FEBS 1982 | ||
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Summary: Eur. J. Biochem. 128, 113- 117(1982) Q FEBS 1982 'H-NMR Studies on Nucleotide Binding... ) site of native Ca2+ATPase, x lies in the range 240-280". The binding of nucleotides by the Ca2+ATPaseof... "/, sodium dodecyl sulphate and 0.1 M NaOH [32]. Equilibrium Binding of ... |
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Source: Clore, G. Marius - Laboratory of Chemical Physics. National Institutes of Health |
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Collection: Biology and Medicine |
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| 84 | Extracting Molecular Binding Relationships from Biomedical Text Thomas C. RINDFLESCH | ||
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Summary: Extracting Molecular Binding Relationships from Biomedical Text Thomas C. RINDFLESCH National... assertions about macromolecular binding relationships from biomedical text. We de- scribe the domain... ~ abstracts, during which almost 25,000 binding relationships suitable for entry into a database of macro |
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|
Source: Association for Computational Linguistics (ACL) Anthology |
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Collection: Computer Technologies and Information Sciences |
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| 85 | Sequence Preference in RNA Recognition by the Nucleoporin Received for publication,September 5, 2006, and in revised form, January 18, 2007 Published, JBC Papers in Press,January 22, 2007, DOI 10.1074/jbc.M608477200 | ||
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Summary: in binding ability was observed only among mRNA fragments of 150 nucleotides or less. While this pointed... - mining factor as structured RNAs, even if greater than 150 nucleotides, do not bind to the Nup153 RBD... on specific nucleotide distribution and arrangement. Although the ... |
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Source: Ullman, Katie - Huntsman Cancer Institute, University of Utah |
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Collection: Biology and Medicine |
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| 86 | Real-time NMR Study of Guanine Nucleotide Exchange and Activation of RhoA by PDZ-RhoGEF*S | ||
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Summary: with the nucleotide phosphate groups and a magne- sium ion that is required for high affinity nucleotide binding (low... between the DH domains and Rho GTPases induce struc- tural changes of the nucleotide binding pocket... -step binding model. RhoA ... |
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Source: Ikura, Mitsuhiko - Division of Molecular and Structural Biology, University of Toronto |
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Collection: Biotechnology ; Biology and Medicine |
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| 87 | Nucleotide-Directed Growth of Semiconductor Nanocrystals Sean Hinds, Bradford J. Taft, Larissa Levina, Vlad Sukhovatkin, Chad J. Dooley, Marc D. Roy, | ||
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Summary: of ligand), the ligand binds to Pb2+ and prevents formation of bulk semiconductor. Here, the nucleotide:Pb2... Nucleotide-Directed Growth of Semiconductor Nanocrystals Sean Hinds, Bradford J. Taft, Larissa... on nucleotides s including both backbone phosphate groups and base functionalities available s are ... |
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Source: |
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Collection: Engineering ; Materials Science |
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| 88 | Molecular Cell, Vol. 20, 493501, November 23, 2005, Copyright 2005 by Elsevier Inc. DOI 10.1016/j.molcel.2005.11.007 An Essential Connection: Link | ||
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Summary: is critical for these regulated interactions: the w44 kDa N-terminal nucleotide binding domain (NBD... -lobed NBD having two subdomains, IA and IIA, forming the base of the deep nucleotide binding cleft; and (2... Structure The nucleotide binding domain (NBD) and b ... |
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Source: Craig, Elizabeth A - Department of Biochemistry, University of Wisconsin at Madison; D' Silva, Patrick - Department of Biochemistry, Indian Institute of Science, Bangalore |
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Collection: Biology and Medicine |
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| 89 | Disorder-order folding transitions underlie catalysis in the helicase motor of SecA | ||
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Summary: RecA-like10 domains: the discontinuous nucleotide-binding domain (NBD; Fig. 1a) and the intramolecular... changes are elicited by nucleotide binding at all. Here, we have combined NMR, thermodynamic... , the nucleotide-binding site in SecADC appears unstable, as regions of IRA2 lining the cleft (b-strands 1 ... |
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|
Source: Kalodimos, Charalampos "Babis" - Department of Chemistry and Chemical Biology, Rutgers University |
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Collection: Chemistry ; Biology and Medicine |
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| 90 | This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research | ||
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Summary: guanine nucleotide-binding pro- tein)-coupled receptors couple to heterotrimeric G proteins to relay... in the conserved 5 helix of Gi, which extends from the C-terminal region to the nucleotide-binding pocket, cause... Heterotrimeric guanine nucleotide-binding regula- tory proteins, G proteins (G),1,2 relay signals from |
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Source: Sakmar, Thomas P. - Laboratory of Molecular Biology and Biochemistry, Rockefeller University |
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Collection: Biology and Medicine |
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| 91 | Ab Initio Prediction of Transcription Factor Targets Using Structural Knowledge | ||
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Summary: the exact archi- tecture of interactions between nucleotides and amino acids at the DNA-binding domain... to the nucleotide. Then, we need to collect statistics about the DNA-binding preferences in this context. This can... the exact interactions between specific residues in the DNA- ... |
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|
Source: Batzoglou, Serafim - Department of Computer Science, Stanford University; Zhong, Sheng - Department of Bioengineering, University of Illinois at Urbana-Champaign |
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Collection: Biology and Medicine ; Biotechnology ; Computer Technologies and Information Sciences |
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| 92 | Highly Organized but Pliant Active Site of DNA Polymerase b: Compensatory Mechanisms in Mutant Enzymes Revealed by | ||
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Summary: -type enzyme, we interpret experimentally derived nucleotide binding affinities in molecular terms: R283A... might increase the nucleotide binding affinity more than D276V; and R283A/K280A might decrease... the nucleotide binding affinity and increase misinsertion ... |
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Source: Schlick, Tamar - Department of Chemistry, New York University |
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Collection: Chemistry |
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| 93 | Kinesinmicrotubule binding depends on both nucleotide state and loading direction | ||
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Summary: Kinesinmicrotubule binding depends on both nucleotide state and loading direction Sotaro Uemura... the nucleotide-dependent binding mode, we measured the unbinding force for one-headed kinesin het- erodimers... -headed kinesin is involved in single-headed binding, both in the absence of ... |
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|
Source: Ishiwata, Shin'ichi - Department of Physics, Waseda University; Kinosita Jr., Kazuhiko - Department of Physics, Waseda University |
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Collection: Biology and Medicine ; Physics |
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| 94 | TheJournalofGeneralPhysiology 333 J. Gen. Physiol. The Rockefeller University Press 0022-1295/2003/09/333/16 $8.00 | ||
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Summary: Nonhydrolytic Interaction of Nucleotide with CFTR's NH2-terminal Nucleotide Binding Domain and its Role... nucleotide-binding domains (NBDs) thought to bind and hydrolyze ATP. In hydrolyzable nucleoside triphosphates... at NBD1 from that at NBD2. To examine simple ... |
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Source: Gadsby, David - Laboratory of Cardiac/Membrane Physiology, Rockefeller University |
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Collection: Biology and Medicine |
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| 95 | 1999 Macmillan Magazines Ltd A structural change in the kinesin motor | ||
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Summary: . This catalytic core bears a striking structural simi- larity to the nucleotide-binding core of the actin... on the microtubule upon nucleotide binding. The orientation of the atomic structure in the cryo-EM maps must... is displaced from the tip of the catalytic core in the absence of nucleotide and ... |
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Source: Vale, Ron - Department of Cellular and Molecular Pharmacology, University of California at San Francisco |
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Collection: Biology and Medicine |
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| 96 | Summary and general discussion Even though DNA has the very important task of storing all genetic information its | ||
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Summary: nucleotide binding pocket, a structural feature also observed in UvrB. In UvrB this pocket was proposed... since its proteins directly remove the aberrant group or catalytically revert the modified nucleotide... . Examples of these are base excision repair (BER), UV damage endonuclease (UVDE) repair and ... |
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Source: van den Brink, Jeroen - Leiden Institute of Physics, Universiteit Leiden |
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Collection: Physics |
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| 97 | Thermophilic P-loop transport ATPases: Enzyme function and energetics at high temperature | ||
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Summary: Thermodynamics of the ATP hydrolysis cycle of GlcV, the Nucleotide Binding Domain of the Glucose ABC transporter... of Sulfolobus solfataricus 43 Chapter 4 Structural Stability of GlcV, the Nucleotide Binding Domain |
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Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 98 | J . Mol. Biol. (1981)145, 105-121 Interactions of Bacteriophage T4-coded Gene 32 Protein | ||
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Summary: of intrillsic protein fluorescence on pol-nucleotide binding to establish additional values of Kw. (ii)Sult back... with Nucleic Acids 11. Specificity of Binding to DNA and RNA Institute of Molecular Biology and Department... August 1980) In this paper we examine the specificity of the co-operative binding ... |
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Source: Kowalczykowski, Stephen C. - Section of Microbiology, University of California, Davis |
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Collection: Biology and Medicine |
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| 99 | The Genetic Code and Transcription The Flow of Information in Cells from the Occurs Using the Following General | ||
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Summary: to Determine the Actual Sequence of the Codons It Relied on the Fact Ribosomes Can Bind a (3 Nucleotide... of Characteristics of the Genetic Code:- 1) The Genetic Code is Written in the Linear of the DNA Nucleotides... by the Base Sequence of 3 Nucleotides, and this is Called a . 3) A Single Sequence of 3 ... |
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Source: Cutler, Chris - Department of Biology, Georgia Southern University |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 100 | Mge1 Functions as a Nucleotide Release Factor for Ssc1, a Mitochondrial Hsp70 of | ||
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Summary: ®cant coop- erativity in nucleotide binding to Ssc1, addition of unlabeled nucleotide should have no effect... nucleotides indicates that Ssc1-3 neither stably binds nor functionally interacts with Mge1. The role... binding of ATP. ADP release is stimulated by ... |
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Source: Craig, Elizabeth A - Department of Biochemistry, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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