Summary:  these stations were also analyzed for contaminant bioaccumulation, using 28-day laboratory exposures... Environmental Research 105 (2007) 145­155 Patterns and trends in sediment toxicity in the San... toxicity has been documented throughout the San Francisco Estuary since the mid-1980s. Studies conducted

Source: San Francisco Estuary Institute

Collection: Environmental Sciences and Ecology

Summary:  to treatment required that the patient be followed for up to 28 days after treatment onset. Consequently... repeat dose trial of the fusion protein PNU- 214565 in patients with advanced gastrointesti- nal... the most common toxicities. Eight dose-limiting toxicities ...

Source: Emory University, Winship Cancer Institute, Biostatistics Research and Informatics Group

Collection: Biology and Medicine

Summary:  included two 10-day, water-only PCBZ uptake and toxicity experiments and a 28-day PCBZ uptake and toxicity... observed toxicity in the 28-day study was a decrease in growth rate compared to the control (Figure 5... species of organisms for a ...

Source: Great Lakes Environmental Research Laboratory, NOAA

Collection: Environmental Sciences and Ecology

Summary:  Alternative Testing 4. OTHER ACTIONS ACROSS THE HEALTH THEME 4.2.9 Towards the replacement of repeated dose... Funding Schemes and particular requirements4 HEALTH.2010.4.2-9: Towards the replacement of repeated dose... of endpoints and intermediate markers in human-based target cells with relevance for ...

Source: Milano-Bicocca, Università - Dipartimento di Informatica, Sistemistica e Comunicazione, Laboratory of Test and Analysis

Collection: Engineering ; Computer Technologies and Information Sciences

Summary:  -CSF at 250 mcg/m2 was administered subcutaneously on days 15 through 28 of each 28-day cycle. The study... the findings of a multicenter trial designed to examine the safety and efficacy of single and repeated dosing... pain. There were 48 patients given repeated ...

Source: Jadvar, Hossein - Departments of Biomedical Engineering & Radiology, University of Southern California

Collection: Biology and Medicine ; Engineering

Summary:  by transport to lysosomal compartments. In monkey administration of single and repeated doses of A24 did... not induce significant toxicity except a slight decreased of haemoglobin level, increased of transferin

Source: Ecole Polytechnique, Centre de mathématiques

Collection: Mathematics

Summary:  already been described in the literature to optimize the conditions for a 28-day test to examine growth... ECOSYSTEM COMPONENT CHARACTERIZATION 513 Figure 6.137 Ceriodaphnia dubia used for toxicity Figure... 6.138 Sediment toxicity tests at Wright State. tests at Wright State. Figure 6.139 Microtox

Source: Pitt, Robert E. - Department of Civil and Environmental Engineering, University of Alabama

Collection: Environmental Management and Restoration Technologies

Summary:  , if 16 fl oz/A is used there is a 28 days waiting period before planting soybean. Considerations Using 2... www.btny.purdue.edu/weedscience/ Poison Hemlock ­ The Toxic Parsnip We often get questions about... (Conium maculatum L.). Although these two plants may look similar, poison hemlock is toxic to cattle

Source: Ginzel, Matthew - Department of Entomology, Purdue University

Collection: Biology and Medicine ; Environmental Sciences and Ecology

Summary:  -term toxicity tests address chronic effects, but must be conducted for 28 days or longer. Due to the long... be conducted by exposing organisms within the scope of a traditional 28-day bioaccumulation test. In addition... for an additional 10 days. At the end of the ...

Source: Great Lakes Environmental Research Laboratory, NOAA

Collection: Environmental Sciences and Ecology

Summary:  an evaluation of the Maximum Repeatable Dose (MRD) and possibly local irritancy. #15; Repeat-dose toxicity... following the de#12;nitive single-dose studies. Repeat-dose toxicity. Similar to the single-dose studies... . The various steps involved in the safety ...

Source: Danmarks Tekniske Universitet, Informatics and Mathematical Modelling

Collection: Mathematics ; Computer Technologies and Information Sciences

Summary:  .............................................................................................33 Measures of allergenicity characteristics, acute oral toxicity, and broiler growth...........36... . Characteristics of amino acid toxicity safety tests .........................................44 Part Three... significant differences between LY038 and the ...

Source: Hickman, Mark - Department of Mathematics and Statistics, University of Canterbury

Collection: Mathematics

Summary:  falling within 28 days of incubation with the microbial inoculate, usually consisting of wastewater... toxicity and biodegradation of ionic liquids A synthesis A broad, interdisciplinary effort is being made... to understand the chemical and environmental factors controlling IL toxicity and degradation and ...

Source: Bernot, Randall - Department of Biology, Ball State University

Collection: Environmental Sciences and Ecology

Summary:  the rebar must be filled solid with concrete or grout. e.all concrete must be a minimum 3000 psi, 28-day... to contain toxic or hazardous materials. 1.2 Exemptions ~ all aboveground, indoor storage facilities, except... , or maintain the existence of any new or existing aboveground indoor toxic/hazardous ...

Source: Brookhaven National Laboratory, Environmental Chemistry Division, Department of Applied Science

Collection: Environmental Sciences and Ecology

Summary:  bioaccumulated, yet may not be detected using the above study design. The EPA has a benthic invertebrate 28-day... ) evaluations are essential to separate point source and nonpoint source toxicity effects from physical effects... , or elevated water temperatures. In addition, a fourth major assessment component ...

Source: Pitt, Robert E. - Department of Civil and Environmental Engineering, University of Alabama

Collection: Environmental Management and Restoration Technologies

Summary:  to 0) 14 days exposure in water followed by 28 days exposure to sub-zero temperature Survival of egg... in water followed by 28 days exposure to sub-zero temperature Survival of egg capsules (hatchability) ANOVA... ­900) Low temperature (-6 to 1.4) 28 days exposure ...

Source: Kramarz, Paulina - Institute of Environmental Sciences, Uniwersytet Jagiellonski

Collection: Environmental Sciences and Ecology

Summary:  in the standard fashion and bevacizumab was given at a dose of 10 mg/kg on days 1 and 15 of each 28-day cycle... for repeated dosing. Insulin-like Growth Factor 1 Receptor (IGF-1R) Cixutumumab (IMC-A12) is a fully human... /gemcitabine and platinum/gemcitabine combinations but it must be5 ­7 balanced by ...

Source: Ecole Polytechnique, Centre de mathématiques

Collection: Mathematics

Summary:  -p-dioxin 28-d 28 days 30-min 30 minutes 48-h 48 hours 7-d 7 days 8-d 8 days 96-h 96 hours AOC Area of Concern... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . li Figure ES.3 Areal extent of sediment toxicity in the Assessment Area . . . . . . . . . . lii... .3.2 ...

Source: Borevitz, Justin - Department of Ecology and Evolution, University of Chicago

Collection: Environmental Sciences and Ecology

Summary:  Photos: "Huge" Toxic Sludge Flood Hits Hungary http... ://news.nationalgeographic.com/...otogalleries/101006-chemical-flood-toxic-sludge-hungary-world-pictures/#/hungary-chemical-flood-aerial_27248_600x450... .jpg[10/8/2010 1:36:20 PM] Armored Against Toxic Sludge Photograph by Bela Szandelszky, AP A Hungarian

Source: Rock, Chris - Department of Biological Sciences, Texas Tech University

Collection: Biology and Medicine

Summary:  for the fluorene study. Upon experi- ment completion, (28 days) surviving amphipods were used for body residue... evidence to support toxicity additivity for PAH mixtures Peter F. Landrum a,*, Guilherme R. Lotufo b... additively when exposed as congener mixtures. Additive internal concentrations at the site of ...

Source: Great Lakes Environmental Research Laboratory, NOAA

Collection: Environmental Sciences and Ecology

Summary:  on Day ­1, of which 4 replicates are used for 28-day growth and survival endpoints and 8 replicates... of comparison for the test assays. It is expected that the minimum detectable difference for 28-day survival... APPENDIX D Toxicity and Bioaccumulation Testing CONTENTS General ...

Source: Pitt, Robert E. - Department of Civil and Environmental Engineering, University of Alabama

Collection: Environmental Management and Restoration Technologies

Summary:  ­ February 6, 2002 I TOXICANT ­ RECEPTOR INTERACTIONS (T + R TR RESPONSE) A. Examples of some cell receptors... (plasma membrane, etc.) 3. Cellular macromolecules (DNA, RNA, tubulin, etc.) B. Examples of Toxicant... --DISTRIBUTION--METABOLISM--EXCRETION A. ADME are interrelated and toxic effect depends upon ADME cycles ­ In ...

Source: Kane, Andrew S. - Aquatic Pathobiology Center & Department of Veterinary Medicine, University of Maryland at College Park

Collection: Biology and Medicine

Summary:  observed by TRS in a 28-day sediment toxicity study with Chironomis tentans (TRS 1997). A concurrent 14-day... as well as preliminary toxicity data for DDAC in sediments. The measured and expected concentrations... (Redenbach 1997). Al- though much less IPBC is used than DDAC, its ...

Source: 

Collection: Environmental Sciences and Ecology ; Multidisciplinary Databases and Resources

Summary:  Mammalian Toxicology · Pharmacokinetics (ADME) · Acute toxicity · Repeated dose toxicity If available... difficulties in defining these materials, the state of knowledge on human or environmental toxicity... should be considered in terms of potential effects of ...

Source: Ecole Polytechnique, Centre de mathématiques

Collection: Mathematics

Summary:  ............................................................ H-1 1. Highly Toxic... ........................................................................ H-2 4. Reproductive Toxicants.................................................................. H... to a relatively lower toxicity. B. Particularly Hazardous Substances ...

Source: Borenstein, Elhanan - Department of Genome Sciences, University of Washington at Seattle

Collection: Biology and Medicine

Summary:  Episodic Toxicity in the San Francisco Bay System Prepared by R. Scott Ogle, Ph.D., Pacific Eco... -Risk Laboratories Andrew J. Gunther, Ph.D., Applied Marine Sciences 1999 Annual Report for the Episodic Toxicity... Pilot Project Regional Monitoring Program for Toxic Substances in the San Francisco Estuary San

Source: San Francisco Estuary Institute

Collection: Environmental Sciences and Ecology

Summary:  levels calcu- lated after 28 days were comparable with those found after 56 days. The test procedure... acute toxicity test' (OECD, 1984; EEC, 1985). This 14-day LCs0 test using the earthworm Eisenia fetida... ., 1992). The end point of the 'earthworm acute toxicity test' is mortality. However, mortality

Source: Hopkin, Steve - School of Biological Sciences, University of Reading

Collection: Environmental Sciences and Ecology

Summary:  values to be nonacutely toxic to freshwater mussels. Chronic Cu toxicity tests (28 day) conducted in hard... of toxicant exposure in aquatic environments. The toxic effects of Cu on the early life stages of freshwater... , can alter growth, filtration efficiency, ...

Source: Cope, W. Gregory - Department of Environmental and Molecular Toxicology, North Carolina State University

Collection: Environmental Sciences and Ecology

Summary:  .................................................................................... 18 The Use of Animals in Toxicity Studies... -the-counter medications and more "toxic" than chemicals that occur naturally in food and the environment. Actually... , pesticides are intention- ally designed to be toxic to plant, animal, or ...

Source: Purdue University, Department of Forestry and Natural Resources, Human-Environment Modeling and Analysis Laboratory

Collection: Environmental Sciences and Ecology

Summary:  :1 that a DLT will be manifest within 28 days. Thus, for each realizable value of c we have Pc( (c)) = 0... of each pa- tient's response to treatment required that the patient be followed for up to 28 days after... are to characterize the toxicity proÿle of a new treatment regimen and to ...

Source: Emory University, Winship Cancer Institute, Biostatistics Research and Informatics Group

Collection: Biology and Medicine

Summary:  ) Referring to the time period prior to the initiation of a toxicity test in which organisms are maintained... in untreated, toxicant-free dilution water or soil with physical and chemical characteristics, e... .g., temperature, pH, hardness, similar to those to be used during the toxicity test. Acute. Involving a stimulus

Source: Pitt, Robert E. - Department of Civil and Environmental Engineering, University of Alabama

Collection: Environmental Management and Restoration Technologies

Summary:  * Acetylcysteine (MucomystTM, AcetadoteTM) Acetaminophen toxicity 20% oral solution-7 x 30mL; 20% IV solution-4 x... Bradydysrhythmias, cholinesterase inhibitor toxicity 1g Benztropine (CogentinTM) Acute dystonia 3 x 2mL, 1mg... , copper, zinc, cobalt, cadmium toxicity 18 x 5mL, 200mg/mL Calcium gluconate 10% Hydrofluoric acid

Source: Provancher, William - Department of Mechanical Engineering, University of Utah

Collection: Engineering

Summary:  .v. injections, developed ascites after 22­28 days, followed by frequent mortality (42). These findings... Chapter 4 Intravenous delivery of adenovirus-mediated soluble FLT-1 results in liver toxicity... FLT-1 Results in Liver Toxicity1 Parameshwar J. Mahasreshti, Manjula Kataram, Ming H. Wang, Cecil R

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

Collection: Biology and Medicine ; Environmental Sciences and Ecology

Summary:  places distinct limits on the use of analytical chemistry to estimate the bioavailability and toxicity... and chronic toxicity tests and bioaccumulation tests. Generic guidance for developing such tests with species... sediment- associated contaminants through the use of acute and chronic toxicity tests and bioaccumulation

Source: US Army Corps of Engineers - Coastal and Hydraulics Laboratory (CERC) Engineer Waterways Experiment Station Vicksburg, MS

Collection: Engineering

Summary:  study Osmotic Pump System N/A 2.5µl/hr 28 day study #12;2 DEVICE DESIGN AND OPERATION Dimensions... treatment method for chronic diseases, it must be refillable to allow repeated dosing for many years. Once... specific and repeatable dose volumes. It will also ...

Source: Meng, Ellis - Department of Biomedical Engineering, University of Southern California

Collection: Engineering ; Materials Science ; Biology and Medicine

Summary:  Fraser River, the highest toxic burdens were observed in eagles, followed by herons and cormorants... biochemical responses (which are biomarkers of a mediated toxic response by the organism) were induced... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Toxicity of chlorinated hydrocarbons . . . . . . . . . . . ...

Source: 

Collection: Environmental Sciences and Ecology ; Multidisciplinary Databases and Resources

Summary:  , Juvenile Growth Test--28 Days. Paris, France. 20. Weber CI, et al. 1989. Short-term methods for estimating... is neither a consistent summary statistic nor an indicator of safe concentrations of toxic chemicals... does carry the assump- tion of a toxic threshold: that there is no effect below some threshold

Source: Graves, John E. - Virginia Institute of Marine Science, College of William and Mary

Collection: Environmental Sciences and Ecology ; Biology and Medicine

Summary:  to publication `as-ready' via OnlineEarly ­ our average submission to decision time is just 28 days. Online... www.newphytologist.org 239 Research Blackwell Publishing Ltd Cellular toxicity of elsinochrome... pathogen, Elsinoë fawcettii and tested for cellular toxicity. · On irradiation with light, ...

Source: Chung, Kuang-Ren - Citrus Research and Education Center, University of Florida

Collection: Biology and Medicine

Summary:  are typically approached many weeks beyond the standard 28-day duration of sediment bioaccumulation tests (Boese... et al. 1997). The failure to reach steady state within the standard 28-day time frame requires... a 28-day bioaccumulation test method with L. plumu- ...

Source: US Army Corps of Engineers - Aquatic Plant Control Research Program (APCRP)

Collection: Environmental Sciences and Ecology

Summary:  , Ipswich, GB-Suffolk IP5 7 R E , Great-Britain A m Early concerns over the handling of toxic materials... practices are being used. Frequently, the safety procedures adopted for dealing with toxic gases and fumes... reduce the toxic gas concentration to levels below the maximum exposurelimit (MEL). Today, however. much

Source: Ecole Polytechnique, Centre de mathématiques

Collection: Mathematics

Summary:  of contaminants on living organisms are generally evaluated using the basic concepts of acute and chronic toxicity... . Acute toxicity is related to water column concentration, while chronic toxicity is related to the water... will be evaluated in its three components, ambient acute toxicity, ambient chronic ...

Source: Melching, Charles S. - Department of Civil and Environmental Engineering, Marquette University

Collection: Environmental Sciences and Ecology ; Engineering

Summary:  individuals had molted by 28 days. The majority of controls molted by 21 days, and the rest completed ecdysis... - pleting ecdysis by 28 days. There was no mortality in lead, cadmium, or clean water in any... molted by 28 days. After 2'h wk, the eight crabs remaining ...

Source: National Oceanic and Atmospheric Administration (NOAA), Fishery Bulletin

Collection: Environmental Sciences and Ecology

Summary:  Ozone The Campus Toxic Gas Program specifies minimum requirements for safe storage, use, and handling... of toxic gas on the UC Berkeley Campus. This program has been approved by the Laboratory Operations... and Safety Committee and defines toxic gases as gases that cause significant acute health effects at low

Source: Kumar, Sanjay - Department of Bioengineering, University of California at Berkeley

Collection: Biology and Medicine ; Engineering

Summary:  , and histopathol- ogy in a 28-day in situ toxicity test. Captively propagated juvenile shortnose sturgeon (total... the 28-day in situ toxicity test conducted from 4 May to 1 June 2005. The riverine test sites were... 28-day ...

Source: Kwak, Thomas J. - North Carolina Cooperative Fish and Wildlife Research Unit & Department of Zoology, North Carolina State University

Collection: Environmental Sciences and Ecology

Summary:  Chemistry Department Standard Operating Procedure Title: Acutely Toxic Chemicals Updated: October... toxic chemicals wash hands and arms thoroughly. Area: Decontamination procedures vary depending... on the material being handled. The toxicity of some materials can be neutralized with other reagents. All

Source: 

Collection: Chemistry

Summary:  according to potential problemstreat according to potential problems SuppressiveSuppressive Repeated doses... with no management changeRepeated doses with no management change Expensive and results in resistance... , gamma, theta, hemolysinhemolysin Toxicity varies with ...

Source: Omiecinski, Curtis - Department of Veterinary and Biomedical Sciences, Pennsylvania State University

Collection: Biology and Medicine

Summary:  in the standard fashion and bevacizumab was given at a dose of 10 mg/kg on days 1 and 15 of each 28-day cycle... a limitation for repeated dosing. Insulin-like Growth Factor 1 Receptor (IGF-1R) Cixutumumab (IMC-A12... be balanced by increased toxicity. Up to now, the only combination ...

Source: Ecole Polytechnique, Centre de mathématiques

Collection: Mathematics

Summary:  The purpose of this technical memorandum is to present plant toxicity data and discuss their utility... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2-3 3. TOXICITY DATA REVIEW... with respect to their toxicity to plants. This report presents a standard method for deriving benchmarks

Source: Pint, Bruce A. - Materials Science & Technology Division, Oak Ridge National Laboratory

Collection: Materials Science

Summary:  . As an example, some chronic toxicity tests for aquatic species use an exposure duration of 28 days regardless... with exposure to a toxicant concentration for a specified duration although regression models incorporating... concentrations or doses. There are tests, notably effluent ...

Source: Graves, John E. - Virginia Institute of Marine Science, College of William and Mary

Collection: Environmental Sciences and Ecology ; Biology and Medicine

Summary:  -detects in air, the sampling moment was 24 days of sampling over a 28-day period, on a weekly schedule of 6 days... dioxin and furan compounds in the gas. However, some of these compounds are not toxic. Therefore, World... Health Organization has measured the toxicity of each known dioxin and furan (about ...

Source: Columbia University - Waste-to-Energy Research and Technology Council (WTERT)

Collection: Renewable Energy

Summary:  Derived from 28-Day EC50growth Values from Experiment 1 (This Study, Exposed via Food) and 28-Day EC50... soil relative to Cd (C ! ). 28-day EC values in Experiment 1 (this study) 2290 2440 27500 9850 ¹ ! 1... .0 1.07 12.0 4.3 ¹ $ 1 4.7 4.2 23.3 ...

Source: Hopkin, Steve - School of Biological Sciences, University of Reading

Collection: Environmental Sciences and Ecology

Summary:  lysosomes (NRR-time) and mean (ÆSEM) number of cocoons per 10 adult worms (reproduction), following 28 days... Toxicity of nickel to the earthworm and the applicability of the neutral red retention assay JANECK... of Reading, PO Box 228, Reading RG6 6AJ, UK Received 13 March 1998; accepted 14 May 1998 The ...

Source: Hopkin, Steve - School of Biological Sciences, University of Reading

Collection: Environmental Sciences and Ecology

Summary:  Thiocyanate, calcium and sulfate as causes of toxicity to Ceriodaphnia dubia in a hard rock mining... Received in revised form 2 June 2010 Accepted 8 June 2010 Available online 10 July 2010 Keywords: Toxicity... identification evaluation Calcium Sulfate Thiocyanate Ceriodaphnia dubia a b s t r a c t A series of Toxicity

Source: Grosell, Martin - Rosenstiel School of Marine and Atmospheric Sciences, University of Miami

Collection: Environmental Sciences and Ecology ; Biology and Medicine

Summary:  site, all fish survived a 28-day exposure with unchanged hematocrit, leucocrit, and gill histology... . In con- trast, all fish did not survive a 28-day period in any of the wastewaters tested and, in some... , or 28 days) and separate fish cages were used for each ...

Source: Farrell, Anthony P. - Faculty of Land and Food Systems, University of British Columbia

Collection: Environmental Sciences and Ecology ; Biology and Medicine

Summary:  1­4 and 7­11. After 28 days, the mice treated with PAC1 had a lower tumour burden than the control... tumours, but that seems to be relatively non- toxic to normal cells. Many therapies being developed

Source: Hergenrother, Paul J. - Department of Chemistry, University of Illinois at Urbana-Champaign

Collection: Chemistry

Summary:  Investigations of Sediment Elutriate Toxicity at Three Estuarine Stations in San Francisco Bay... ................................................................................................................................... 5 Toxicity Identification Evaluation Strategy... ...

Source: San Francisco Estuary Institute

Collection: Environmental Sciences and Ecology

Summary:  -1541), the Renaissance "Father of Toxicology," in his Third Defense.1 TOXIC overdose can present with a great variety... of a poisoned patient depends largely on the specific toxicity of the agent and the quality of care delivered... sub-toxic amounts who receive decon- tamination at a set post-ingestion time, or involve mildly

Source: Louisiana State University Health Sciences Center in New Orleans, Department of Biochemistry and Molecular Biology

Collection: Biology and Medicine

Summary:  of patients at the same disease stage. Repeated dosing with radiolabeled antibody or combination of RIT... (9):3621-3628. 29. Peterson JA, Blank EW, Ceriani RL: Effect of multiple, repeated doses of radioimmunotherapy... , objective tumor responses were obtained with limited toxicity ...

Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique

Collection: Physics

Summary:  a repeated dosing regimen.14-17 For example, a 1:6 fixed combination of the trioxane artemether and lume... survival to 28 days; a slightly higher single oral dose of dimer 4b (54 mg/kg) along with mefloquine... /kg) alone prolonged average survival to only day 11. Neither overt toxicity ...

Source: Hergenrother, Paul J. - Department of Chemistry, University of Illinois at Urbana-Champaign

Collection: Chemistry

Summary:  of treatment, Ton, versus the death rate of sensitive cancer cells during therapy, c1, for a 28-day treatment... considering drug toxicity and side effects as constraints. Our methodology can be used to identify optimum... #12;by rest periods to allow for recovery from toxicity. Clinical studies evaluating ...

Source: 

Collection: Biology and Medicine

Summary:  on toxicity studies, the draft interim guideline for the protection of freshwater life is set at 1.5 µg... contained levels of both DDAC and IPBC to concentrations of 1.26 and 0.49 µg/g, respectively. Toxicity... the potential for toxic effects from sediments contaminated with DDAC. The acute toxicity was ...

Source: 

Collection: Environmental Sciences and Ecology ; Multidisciplinary Databases and Resources

Summary:  cellular toxin) for 12­28 days accumulated the toxin (24 ± 7 to 527 ± 330 ngg­1 MC-LReq; mean ± SE... ) and 18 days (Driedmeat Lake) to 28 days (Coal Lake). Phytoplankton were collected for toxin analysis... is developing on the relationship between toxic cyanobacteria and other ...

Source: Campbell, Linda - Department of Biology, Queen's University (Kingston)

Collection: Environmental Sciences and Ecology ; Biology and Medicine

Summary:  EC20 values for fish are from 28-day embryo-larval tests with Pimephales promelas. Kimball (n... are from Kimball (n.d.). The chronic tests of Pimephales promelas were embryo-larval, and 28-day life... Toxicant Concentration NAWQC National Ambient Water Quality Criteria NOEC No Observed ...

Source: Pint, Bruce A. - Materials Science & Technology Division, Oak Ridge National Laboratory

Collection: Materials Science

Summary:  to high occupancy. The length of stay of patients in ICU has varied from 5-28 days, with one ICU... in convalescent plasma. In animal models using mAb repeated doses (days 1 and 3) showed more rapid elimination... . · No toxic or adverse events were seen in mice or ferrets during mAb ...

Source: Rambaut, Andrew - School of Biological Sciences, University of Edinburgh

Collection: Biology and Medicine

Summary:  constitute first-line therapy, with repeat dosing as necessary.33 Asymptomatic patients should be observed... 2 EBMedicine.net · March 2010 and their lack of awareness about what constitutes a true toxic... ingestion. Childhood exposures are largely preventable if one recognizes the toxic potential of ...

Source: Louisiana State University Health Sciences Center in New Orleans, Department of Biochemistry and Molecular Biology

Collection: Biology and Medicine

Summary:  Chemistry Department Standard Operating Procedure Title: Acutely Toxic Gases Updated: October... 2010Prabha Dwivedi A list of acutely toxic gases should be available outside of the laboratory where... hands and arms with soap and water immediately after handling acutely toxic gases. Designated area

Source: 

Collection: Chemistry

Summary:  , Silva VM, Hennig GE, Whiteley HE. Repeated dosing with the peroxisome proliferator clofibrate decreases... Peroxisome Proliferator-Activated Receptor- / Protects Against Chemically Induced Liver Toxicity... is less clear. To determine the role of PPAR / in chemically induced liver toxicity, wild-type and ...

Source: Andrews, Anne M. - Huck Institutes of the Life Sciences, Pennsylvania State University

Collection: Biology and Medicine

Summary:  Ambient Water Toxicity in San Francisco Bay: 1993-2002 Dr. Scott Ogle, Pacific EcoRisk Dr. Andrew... Toxicity Tests: · Bivalve embryo test w/ Mytilus and Crassostrea · Algal growth test w/ diatom... Thalassiosira Results: No toxicity observed Thalassiosira exhibited biostimulation #12;RMP Status & Trends

Source: San Francisco Estuary Institute

Collection: Environmental Sciences and Ecology

Summary:  Toxicity in Early Phase Clinical Trials Andre´ Rogatko,1 James S. Babb,1 Hao Wang,1 Michael J. Slifker,1... , medical and treatment history, doses of ex- perimental agents, and graded toxicities were extracted from... case report forms. We developed a novel summary measure, the toxicity index (TI), to better

Source: Emory University, Winship Cancer Institute, Biostatistics Research and Informatics Group

Collection: Biology and Medicine

Summary:  or risks? 2-5 June 2009 Toxicity Analysis and Public Health Aspects of Municipal Landfill Leachate: A Case... of these leachates into the environments poses a substantial risk to the origins of potable water. Toxicity analysis... , Okhla municipal landfill leachate was subjected to acute toxicity tests using fish bioassay

Source: Ecole Polytechnique, Centre de mathématiques

Collection: Mathematics

Summary:  (8.96 109 conidia/m2 ) required 28 days to cause >92% cockroach mortality (LT50 10 days). In contrast... mortality was monitored daily for 28 days and each bioassay was replicated twice over time. Bioassays... for 28 days after injection. Bioassays with Boric Acid ...

Source: Schal, Coby - Department of Entomology, North Carolina State University

Collection: Biology and Medicine

Summary:  of the cyanobacterial toxin microcystin-LR to rats after 28 days intake with the drinking water. Env Toxicol 1999... , often several different toxins per species (Carmichael 1994). The main toxic cyanobacterial genera... such as dinoflagellates and diatoms, are extremely toxic to many species. There is a wide ...

Source: Miami, University of - Rosenstiel School of Marine and Atmospheric Sciences, Fisheries Ecosystem Modeling and Assessment Research Group

Collection: Environmental Sciences and Ecology

Summary:  ) was investigated. Concrete mixtures with and without fly ash were proportioned to attain 28-day compressive... was proportioned to have 28-day strength of 6000 psi. The other three mixtures contained the Class C fly ash... the best results at all test ages. At 28 ...

Source: Wisconsin-Milwaukee, University of - Department of Civil Engineering and Mechanics, Center for By-Products Utilization

Collection: Engineering ; Materials Science

Summary:  dose long-term study of 28 days, since it reportedly has lower anticoagulant activity and is suitable... in stable throm- bus formation when administered alone but showed no synergy with oral arginine.A 28-day... activity in a 4-hour and 28-day ...

Source: Linhardt, Robert J. - Center for Biotechnology and Interdisciplinary Studies & Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute

Collection: Biotechnology ; Chemistry

Summary:  Bioremediation of Toxic Pollutants: Jim Field uses microbes to clean the environment of hazardous... to catalyze The transformation of toxic pollutants into environmentally safe end Products. Field's current... to harness bacteria to oxidize toxic Arsenic in situ in groundwater to immobile forms without relying

Source: Wong, Pak Kin - Department of Aerospace and Mechanical Engineering, University of Arizona

Collection: Engineering ; Biology and Medicine

Summary:  results - Relate screening data to known information Model and predict acute toxicity in animals - Relate... large cytotoxicty data sets to animal toxicity(?) Modelling protocols to handle the characteristics... toxicity Characterize toxicity datasets - Structurally and by activity (active chemical ...

Source: Indiana University, Pervasive Technology Laboratories, Community Grids Lab.

Collection: Computer Technologies and Information Sciences

Summary:  Building Room Phone Corrosive Non-Hazardous Ignitable Other (explain)Reactive Toxic Oxidizer UNIVERSITY... Corrosive Non-Hazardous Ignitable Other (explain)Reactive Toxic Oxidizer UNIVERSITY OF WASHINGTON... -Hazardous Ignitable Other (explain)Reactive Toxic Oxidizer UNIVERSITY OF WASHINGTON ENVIRONMENTAL HEALTH AND SAFETY

Source: Borenstein, Elhanan - Department of Genome Sciences, University of Washington at Seattle

Collection: Biology and Medicine

Summary:  in risk or potential danger as you switch to using Pestisafes® or alternative non-toxic (Intelligent Pest... ToxicTimes, 2/99, "Pesticide Safety Questioned" by James Huff, Ph.D. noted: "Unfortunately, pesti- cides... of crop `nd losses o ight along with the increase in ticide f]." The same Our Toxic Times issue stated: "A

Source: Pregibon, Daryl - Google Labs

Collection: Mathematics

Summary:  AccuWeather.com - Irene's Toxic Aftermath http://m.accuweather.com/en/health-articles/allergies/irenes_toxic... _aftermath/54494[9/6/2011 9:35:08 AM] Irene's Toxic Aftermath August 31, 2011; 12:02 PM Photograph Courtesy NASA... , floodwaters become polluted with a host of chemicals from "cars, machinery, gas stations, dry cleaners, ...

Source: Rock, Chris - Department of Biological Sciences, Texas Tech University

Collection: Biology and Medicine

Summary:  healthy for up to 28 days with no change in weight, feeding or behavior. Fin regeneration is a complex... was not determined in this study, however zebrafish exposed to 70 ng/g TCDD re- mained healthy for at least 28 days... . For example, yellow perch receiving a single 25 g/kg TCDD dose demon- strate 95% ...

Source: Tullos, Desiree - Department of Biological and Ecological Engineering, Oregon State University

Collection: Environmental Sciences and Ecology

Summary:  of this system with results from a 28-day test in which juvenile bluegills Lepomis macrochirus were exposed... and Bro-Rasmussen, 1992). We illus- trate the performance of this system with results from a 28-day test... mm, mean weight, 1.97 g) were exposed to resuspended sediment for 28 ...

Source: Cope, W. Gregory - Department of Environmental and Molecular Toxicology, North Carolina State University

Collection: Environmental Sciences and Ecology

Summary:  Testing for Toxic Algae By Tadd Barrow UNL Extension Educator, Water Quality Algae is a microscopic... it toxic to animals, especially humans and dogs. Toxic algae often are naturally occurring from high... . When illness occurs from toxic algae, it's usually because of consumption. Also, mild rashes can occur

Source: Nebraska-Lincoln, University of - Sand Hills Biocomplexity Project

Collection: Environmental Sciences and Ecology

Summary:  ............................................... 127 Table 44. Corbicula fluminea 28-day freshwater solid phase bioaccumulation tests... . ................... 131 Table 45. Corbicula fluminea 28-day freshwater solid phase bioaccumulation tests... . ...................132 Table 46. Corbicula fluminea ...

Source: US Army Corps of Engineers - Aquatic Plant Control Research Program (APCRP)

Collection: Environmental Sciences and Ecology

Summary:  ............................................................................................................ 2-18 3. Highly Toxic Substances... .................................................................................................................................................... 3-4 4. Toxic

Source: Asbury, Chip - Department of Physiology and Biophysics, University of Washington at Seattle

Collection: Biology and Medicine

Summary:  . . . . . . . . . . . . . . . . . . . . . . . . . . . 5-3 6. RELATIONSHIP BETWEEN SOIL TOXICITY BENCHMARKS AND OTHER ECOTOXICOLOGICAL CRITERIA... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6-1 6.1 COMPARISON OF TOXICITY BENCHMARKS FOR CONTAMINANTS IN SOIL TO CANADIAN ENVIRONMENTAL QUALITY... . . . . . . . . . . . . . . . . . . ...

Source: Pint, Bruce A. - Materials Science & Technology Division, Oak Ridge National Laboratory

Collection: Materials Science

Summary:  , usually arising from industrial activity, is challenging because of the inherent toxicity... as amplified toxicity arising from substrate interaction effects in the degradation of xenobiotic mixtures... from toxicity analysis (e.g., EC50) and inhibition constants derived from dedicated kinetic models

Source: Daugulis, Andrew J. - Department of Chemical Engineering, Queen's University (Kingston)

Collection: Biotechnology

Summary:  , 2, 5, 10, 14, and 28 days of exposure. Duplicate beakers (200 ml) for each time point and each... . Accumulated dose of fluoranthene by Lumbriculus variegatus after 10-day and 28-day exposures Sediment... Concentration ( g g 1 ) 10-day Accumulation (mmol kg 1 ) ...

Source: Great Lakes Environmental Research Laboratory, NOAA

Collection: Environmental Sciences and Ecology

Summary:  filaments were tallied. Assays using H. azteca were conducted for 28 days (four weeks) following... H, and temperature were measured prior to adding the amphipods and at the end of the 28-day period. After 28 days... . azteca experiments lasted 28 ...

Source: Great Lakes Environmental Research Laboratory, NOAA

Collection: Environmental Sciences and Ecology

Summary:  A network of protein interactions determines polyglutamine toxicity Martin L. Duennwald*, Smitha... proteins. This toxicity must arise from a combi- nation of the amino acid sequences of the misfolded... example of how profoundly these intramolec- ular and intermolecular factors can modulate the toxicity

Source: Duennwald, Martin L. - Boston Biomedical Research Institute

Collection: Biology and Medicine

Summary:  as between categories. Thus toxicity to humans can vary widely within each group. #12;Pesticide Use: An Old... blindness and malaria Need to make risk/benefit decisions Pesticide Use: An Old Practice #12;Toxicity... of Pesticides Must remember that pesticides are inherently toxic. Many different pesticides in use with very

Source: Kane, Andrew S. - Aquatic Pathobiology Center & Department of Veterinary Medicine, University of Maryland at College Park

Collection: Biology and Medicine

Summary:  ................................................ 10 1.2.3 Water Chemistry and Toxicity... ............................................................................................. 10 1.2.4 Sediment Chemistry and Toxicity... ............................................................................................. 11 1.2.7 Causes of Sediment ...

Source: San Francisco Estuary Institute

Collection: Environmental Sciences and Ecology

Summary:  and repeat at a 28-day interval if necessary. Banol (66.5%) 20.0-30.0 fl oz propamocarb hydrochloride Treat... soil at 3-week to 3-month intervals. Adorn (39.5%) 1.0-4.0 fl oz fluopicolide Apply at 14-28 day... , but not to petunias and impatiens. Segway (34.5% SC) 2.0-6.0 fl oz cyazoflamid Apply at ...

Source: Liskiewicz, Maciej - Institut für Theoretische Informatik, Universität zu Lübeck

Collection: Computer Technologies and Information Sciences

Summary:  TOXICITY OF POLYCYCLIC AROMATIC HYDROCARBONS: II. AN EMPIRICAL MODEL FOR THE TOXICITY OF 16 POLYCYCLIC... -Rhotoinduced toxicity of polycyclic aromatic hydrocarbons (PAHs) occurs via photosensitization reactions (e.g., gen... ) of the chemicals to more toxic species. Thequantitative structure-activity ...

Source: Krylov, Sergey - Department of Chemistry, York University (Toronto)

Collection: Biology and Medicine ; Chemistry

Summary:  in mice Repeat dose toxicity of BL-3050 (60 mg/kg) was assessed following 7 intravenous injections... in mice to assess its toxicity and adverse immune responses. The in vivo efficacy of recombinant PON1... to adverse immune responses. However, we observed no toxic effects in mice ...

Source: Tawfik, Dan S. - Department of Biological Chemistry, Weizmann Institute of Science

Collection: Biotechnology ; Biology and Medicine

Summary:  may have blood specimens drawn up to 28 days before surgery by specially certified Nursing staff

Source: Gleeson, Joseph G. - Department of Neurosciences, University of California at San Diego

Collection: Biology and Medicine

Summary:  : Contaminants and Toxicity 20th ­ 22nd July 2011 This module is one of six in the series developed... of human toxicity data - The practical stuff applicable to my day-to-day work... #12;Module D Program Day 1... Toxicology in human health risk assessments Evaluation of human toxicity data; workshopping and case studies

Source: Baird, Mark - Climate and Environmental Dynamics Laboratory, School of Mathematics and Statistics, University of New South Wales

Collection: Environmental Sciences and Ecology ; Geosciences

Summary:  Program in Toxicology ksquibb@umaryland.edu Our discussion of metal ion toxicity now moves to mercury (Hg... ) and arsenic (As) which have much more complex chemistries than Pb and Cd in biological systems. #12;2 Toxicity... of Mercury (Hg)Toxicity of Mercury (Hg) Chemistry Inorganic: Elemental Hgo (metallic mercury, quicksilver

Source: Kane, Andrew S. - Aquatic Pathobiology Center & Department of Veterinary Medicine, University of Maryland at College Park

Collection: Biology and Medicine

Summary:  of drugs and cosmetics through the identification of toxicity pathways. Efforts will continue to ensure

Source: Milano-Bicocca, Università - Dipartimento di Informatica, Sistemistica e Comunicazione, Laboratory of Test and Analysis

Collection: Engineering ; Computer Technologies and Information Sciences

Summary:  - tally examined, mimicking human elimination and repeated dosing. Results: Using limited experimental... examined. However, regrowth over time was predicted for suboptimal regimens with repeated dosing due... toxicity). The numerous combinations of these variables involved in designing ...

Source: Nikolaou, Michael - Department of Chemical Engineering, University of Houston

Collection: Engineering

Summary:  -related residual effects following repeated doses administered over consecutive days. © 2007 Elsevier Ireland Ltd... of the residual effects of methamphetamine following repeated dosing over consecutive days. Another caveat... repeated dosing is needed to better ...

Source: Silver, Rae - Department of Psychology, Columbia University

Collection: Biology and Medicine

Summary:  .25a CCR (1990) Pimephales promelas 28 days ­ 1.4b 2.9b WIL (1999) Most data are reported in Leung... Aquatic Toxicology 71 (2005) 283­296 Chronic toxicity of glutaraldehyde: differential sensitivity... the potential for environmental impacts associated with glutaraldehyde, three standard chronic toxicity

Source: Great Lakes Environmental Research Laboratory, NOAA

Collection: Environmental Sciences and Ecology