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Sample search results for: a431 cells overexpressing

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1 Caveolin-1 Phosphorylation in Human Squamous and Epidermoid Carcinoma Cells: Dependence on ErbB1 Expression and Src Activation
 

Summary:  phosphorylation in several human car- cinoma cell lines that are known to overexpress the EGF receptor, i.e., A431... (such as A431 and B82L cells) that overexpress the EGF receptor ([27, 31, 32] and unpublished data... human ...

  

Source: Bertics, Paul J. - Molecular and Cellular Pharmacology Training Program & Department of Biomolecular Chemistry, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
2 [CANCER RESEARCH 61, 63776381, September 1, 2001] Advances in Brief
 

Summary:  ), U118 (glioma), A431 (squamous cell skin cancer), BT474, and MB-453 (breast cancer) were ob- tained... ;Retargeting Assays. SKOV3.ip1, U118, and A431 cells were infected in duplicate with AdCMVLuc preincubated... 200 VP/cell were used for U118 ...

  

Source: Hemminki, Akseli - Department of Biosciences, University of Helsinki

 

Collection: Biology and Medicine

 
3 ORIGINAL ARTICLE Csk-binding protein (Cbp) negatively regulates epidermal growth
 

Summary:  -induced cell signaling by checking its tyrosine phosphorylation in human epithelial carcinoma cell line A431... phosphorylation of endogenous Cbp in both A431 and HEK 293 cells (Figure 1a, upper panel). Co... - noprecipitated using anti-Cbp (a) or ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
4 Reviewer's report The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostateTitle
 

Summary:  prostateTitle: cancer cells Authors: Lifang Lu (lflu@hsph.harvard.edu) Holger Schulz (hschulz... the authors show that androgen-induced G1 cell cycle arrest of LNCaP cells coincides with a downreglation... of the F-box protein Skp2. Adenovirus-mediated overexpression of Skp2 led to downregulation of p27

  

Source: Wolf, Dieter A.- Burnham Institute for Medical Research

 

Collection: Biology and Medicine

 
5 EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast
 

Summary:  Two million A431 cells were implanted subcutaneously into the left flanks of 15 nude CD-1 mice. When... for the treatment of other EGFR over-expressing cancers. We used the A431 (vulval carcinoma, expressing ;2 3 106 EGF... -431 ...

  

Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem

 

Collection: Biology and Medicine

 
6 MOLECULAR AND CELLULAR BIOLOGY, 0270-7306/01/$04.00 0 DOI: 10.1128/MCB.21.20.69136926.2001
 

Summary:  - tylated Ras (NIH 3T3/Ras cells) have been described (17, 26, 35). These and A431 cells were grown... ). Activation of JNK and p38 is correlated with cell death induction in A431 and HT29 cells. Many types of tumor... ...

  

Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem

 

Collection: Biology and Medicine

 
7 Genes overexpressed in different human solid cancers exhibit different tissue-specific expression profiles
 

Summary:  doi 10.1073 pnas.0705824104 #12;blood cells were scored as overexpressed genes. This analysis was thus... normal nonhematopoietic tissues (6, 7), and the colo- rectal carcinoma cell line SW480 also overexpressed... leukemia cells overexpressed genes whose normal ...

  

Source: Domany, Eytan - Physics of Complex Systems, Weizmann Institute of Science

 

Collection: Biology and Medicine ; Physics

 
8 The Prostate 66:779 ^787 (2006) Vascular Endothelial Growth Factor Productionin
 

Summary:  a pertussis toxin sensitive GPCR (Gi/o) in human epidermoid carcinoma A431 cells [24]. To delineate... epidermoid carcinoma A431 cells [24], indicating that this effect may be mirrored in a broad spectrum of cell... Cancer ...

  

Source: Jankun, Jerzy - Departments of Physiology and Molecular Medicine & Urology, Medical College of Ohio

 

Collection: Biology and Medicine

 
9 Secretory Phospholipase A2 Inhibits Epidermal Growth Factor-Induced Receptor Activation
 

Summary:  ) tyrosine phosphorylation in a human epidermoid carcinoma cell line, A-431. Treatment of cells... factor can increase the binding of EGF to A-431 cells by first binding to its own cell surface receptor... ) prevented EGF-in- ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
10 Suppressionof Tumorigenicityby Plakoglobin:An Augmenting Effect of N-Cadherin
 

Summary:  3 cells transformed by SV40, MDCK, and A431 cells were all grown in Dulbecco's modified Ea- gle... - expressing clones. A431 is a cell line from human carci- noma. Bars: (D and F) 50 IxM;(E and G) 10 Ix... . Overexpression of ...

  

Source: Geiger, Benjamin - Department of Molecular Cell Biology, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
11 Overexpression of Bcl-2 Prevents Neomycin-Induced Hair Cell Death and Caspase-9 Activation
 

Summary:  Overexpression of Bcl-2 Prevents Neomycin- Induced Hair Cell Death and Caspase-9 Activation... to examine the role of Bcl-2 in neomycin- induced hair cell death. Overexpression of Bcl-2 signif- icantly... . Furthermore, Bcl-2 overexpression prevented neomycin-induced activation of ...

  

Source: Rubel, Edwin - Department of Physiology and Biophysics, University of Washington at Seattle

 

Collection: Biology and Medicine

 
12 Molecular Biology of the Cell Vol. 19, 33343346, August 2008
 

Summary:  ). For degradation assays, A431 cells or SCC-12F cells grown in six-well plates were serum starved for 2 h in DMEM... with 25 g/ml cycloheximide and stimulated with 100 ng/ml (A431 cells) or 20 nM (SCC-12F cells) epidermal... ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
13 Molecular chaperones and the stress of oncogenesis Dick D Mosser*,1
 

Summary:  overexpressed in cells of various cancers and have been suggested to be contributing factors in tumorigenesis... . Likewise, overexpression of chaper- ones has also been shown to protect cells against apoptotic cell death... Overexpression of Hsp70 can protect ...

  

Source: Morimoto, Richard - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University

 

Collection: Biology and Medicine

 
14 J Biol Chem. Author manuscript Triadin (Trisk 95) overexpression blocks excitation-contraction coupling in
 

Summary:  to differentiation medium. Control cells were infected with the control virus (AdV-DsRed). Trisk 95-over-expressing... myotubes (T95-myotubes) consisted in cells infected with AdV-Trisk 95, and Trisk 51-overexpressing myotubes... in the complex' Trisk 95 or Trisk 51 over-expression was ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
15 Differential Sensitivity in the Survival of Oligodendrocyte Cell Lines to
 

Summary:  Differential Sensitivity in the Survival of Oligodendrocyte Cell Lines to Overexpression of Myelin... , was overexpressed in the cell lines. These results suggest that overexpression of the "classic" PLP or DM20 can... classic and srPLP/DM20s on survival of the OL cell ...

  

Source: Bongarzone, Ernesto R. - Department of Anatomy and Cell Biology, University of Illinois at Chicago

 

Collection: Biology and Medicine

 
16 2006LANDESBIOSCIENCE.DONOTDISTRIBUTE. www.landesbioscience.com Cell Cycle 1397
 

Summary:  , overexpression of 120 genes led to a detectable cell cycle halt and resulted in arrested growth. Consistent... the overexpression array for systematic SDL screening. We #12;1400 Cell Cycle 2006; Vol. 5 Issue 13 merged our... , overexpression of an unmodifiable substrate might be ...

  

Source: Pál, Csaba - Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences

 

Collection: Biology and Medicine

 
17 DNA AND CELL BIOLOGY Volume 23, Number 3, 2004
 

Summary:  of protein tyrosine phos- phatase (PTP) SHP-1 or SHP-2, epithelial cells like A431, HeLa, and 293 express... , especially when this protein is overexpressed in 293 cells. In contrast with wild-type SIRPa, its dominant... from 2 3 106 of 293, HeLa, primary human fibroblasts MRC5, or 293 ...

  

Source: Ullrich, Axel - Max-Planck-Institut für Biochemie

 

Collection: Biology and Medicine

 
18 c-Src trafficking and co-localization with the EGF Receptor promotes EGF ligand-independent EGF Receptor Activation and
 

Summary:  from clathrin mediated endocytosis [31­33]. In A431 cells, macropinosomes remain as discrete... -mediated induction of cell growth and motility [7,8]. Overexpression of both c-Src and EGFR leads... was detected in c-Src overexpressing cells even ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
19 Inadequate inhibition of host RNA polymerase restricts T7 bacteriophage growth on hosts
 

Summary:  the inhibition of T7 growth in cells overexpressing udk. Interestingly, muta- tions in the very strong promoters... suppressors that permit growth on cells overexpressing udk To test the hypothesis above, we carried out... of suppressors that both allow T7 to grow on cells ...

  

Source: Richardson, Charles C. - Department of Biological Chemistry and Molecular Pharmacology, Harvard University

 

Collection: Biology and Medicine

 
20 Overexpression of Active Aurora-C Kinase Results in Cell Transformation and Tumour Formation
 

Summary:  Overexpression of Active Aurora-C Kinase Results in Cell Transformation and Tumour Formation Jabbar... transiently transfected cells and in stable cell lines. Only stable NIH3T3 cell clones overexpressing active... is sufficient to transform ...

  

Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique

 

Collection: Physics


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21 The SKP1 -Cul1 -F-box and Leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates lysine demethylase 4A (KDM4A)/Jumonji domain-containing 2A (JMJD2A).
 

Summary:  - containing 2A (KDM4A/JMJD2A) is tightly regulated during the cell cycle. Overexpression of JMJD2A leads... turnover. Interestingly, ubiquitin overexpression increased JMJD2A protein turnover in cells stably... . A total of 2,408 JMJD2A peak locations in the JMJD2A overexpressed ...

  

Source: Yuan, Guo-Cheng "GC" - Dana-Farber Cancer Institute, Harvard University

 

Collection: Biology and Medicine

 
22 dna repair 7 ( 2 0 0 8 ) 686693 available at www.sciencedirect.com
 

Summary:  .elsevier.com/locate/dnarepair Mini review The consequences of Rad51 overexpression for normal and tumor cells Hannah L. Klein... . Overexpression of Rad51 in different organisms and cell types has a wide assortment of consequences, rang- ing... is often mutated in tumor cells, there is a ...

  

Source: Roth, David B. - Langone Medical Center, New York University

 

Collection: Biology and Medicine

 
23 COMMUNICATION Regulation of neuritogenesis and synaptic transmission
 

Summary:  outgrowth around the cell body (Fig. 1c, 1 and 2). Moreover, Aplysia neurons overexpressing msec7-1 began... overexpressing msec7-1 generate neurite-like processes on the cell body. Moreover, this was not (a) (b) Fig. 2... factor (ARF) family of small GTPases. Here, we report that msec7-1 ...

  

Source: Kim, Eunjoon - Department of Biological Sciences, Korea Advanced Institute of Science and Technology

 

Collection: Biology and Medicine

 
24 The role of uPAR signaling in lung cancer Background and significance
 

Summary:  PAR expression induces stem-cell-like qualities in SCLC cells. Initially, uPAR will be over-expressed in several... in the number, size, or morphology of the cells over-expressing uPAR versus the control cells will be noted. CLC... clumps. It is anticipated that the ...

  

Source: Gleeson, Joseph G. - Department of Neurosciences, University of California at San Diego

 

Collection: Biology and Medicine

 
25 TRIADIN (TRISK 95) OVER-EXPRESSION BLOCKS EXCITATION-CONTRACTION COUPLING IN RAT SKELETAL MYOTUBES
 

Summary:  , and the physiological behaviour of the modified cells was analyzed. Over-expression did not modify the expression level... virus (AdV-DsRed). Trisk 95- overexpressing myotubes (T95-myotubes) consisted in cells infected with Ad... over-expression was induced by adenoviral infection. ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
26 Molecular Biology of the Cell Vol. 14, 29082920, July 2003
 

Summary:  on overexpression studies in mamma- lian cells. These data suggest that the arfophilin family may represent a point... purified recombinant arfophilin-1 or -2, or the protein overexpressed in cells revealed... identify the Arf-overexpressing cells, indicated here by ...

  

Source: Sullivan, William T. - Department of Molecular, Cell, and Developmental Biology, University of California at Santa Cruz

 

Collection: Biology and Medicine

 
27 Molecular specific optoacoustic imaging with plasmonic nanoparticles
 

Summary:  , "Consumption of EGF by A431 cells: evidence for receptor recycling," J. Cell. Biol. 120, 85-93 (1993). 12. K... epithelial carcinoma cells (A431 keratinocyte) were used: (1) the control tissue phantom with no gold... PEG-SH in deionized water. ...

  

Source: Texas at Austin, University of - Department of Biomedical Engineering, Ultrasound Imaging and Therapeutics Research Laboratory

 

Collection: Engineering ; Biology and Medicine

 
28 Evolution of viral development of RNA phage
 

Summary:  adaptation to overexpression We evolved viral populations on host cells that carry pRep, pCoat, pLys for 20... for viral development and evolution we over-expressed each of the four genes of RNA phage MS2 during... overexpression provides viral gene products `for free', this disturbance reduced viral burst ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
29 Neurobiology of Disease -Synuclein Overexpression in PC12 and Chromaffin Cells
 

Summary:  Neurobiology of Disease -Synuclein Overexpression in PC12 and Chromaffin Cells Impairs... ),aproteinimplicatedinParkinson'sdiseasepathogenesis,isapresynapticproteinsuggestedtoregulatetransmitter release. We explored how -syn overexpression in PC12 and chromaffin cells, which exhibit low endogenous... ...

  

Source: Sulzer, David - Departments of Neurology & Psychiatry, Columbia University

 

Collection: Biology and Medicine

 
30 SUPPLEMENTARY MATERIAL Integration of Insulin Receptor/FOXO signaling and dMyc activity during
 

Summary:  -F") Overexpression of Cyclin E (CycE) in muscles blocks muscle growth and variation of nuclear size, in comparison... with control (E-E"). This indicates that the endoreplicative cell cycle is involved in ploidy variation, which... (adepithelial) layer of wing imaginal discs (WID), and few cells in the brain (not shown). ...

  

Source: Higgins, Darren - Department of Microbiology and Molecular Genetics, Harvard University

 

Collection: Biology and Medicine

 
31 BioMedCentral Dieter A. Wolf, M.D.
 

Summary:  To: BioMedCentral Editors Dieter A. Wolf, M.D. Department of Cancer Cell Biology Harvard School... -box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells... prostate cancer cells. The phenomen of androgen-induced cell cycle arrest in LNCaP cells ...

  

Source: Wolf, Dieter A.- Burnham Institute for Medical Research

 

Collection: Biology and Medicine

 
32 Cancer Cell Survival of Cancer Cells Is Maintained
 

Summary:  expression, respectively (Figure 7A). Both EGFR-expressing cells A431 and PC3-MM2 expressed SGLT1, but MCF-7... analysis demonstrated that SGLT1 was expressed in EGFR-positive cells, A431 and PC3-MM2, but not in MCF-7... . (B) When ...

  

Source: Hardy, Christopher R. - Biology Department, Millersville University

 

Collection: Environmental Sciences and Ecology

 
33 Association of Stomatin with Lipid Bodies* Received for publication, September 24, 2003, and in revised form, February 19, 2004
 

Summary:  proteins from the human A431 cell line and report here the identification of 33 LB proteins, most notably... cells (A431), and MDCK epithe- lial cells, strain II, were maintained in Dulbecco's modified Eagle... of the constructs were checked by ...

  

Source: Schütz, Gerhard J. - Biophysics Institute, Johannes Kepler Universität Linz

 

Collection: Chemistry ; Biology and Medicine

 
34 Biochem. J. (2000) 352, 921927 (Printed in Great Britain) 921 Effects of overexpression of the liver subunit of 6-phosphofructo-1-kinase
 

Summary:  and co-workers have overexpressed, in cells and transgenic mice, some of the genes located on the long... of cell lines overexpressing PFK-1 Cells were transfected with plasmid pBF143, according to the protocol... transfected with the empty vector. The control cell ...

  

Source: Groner, Yoram - Department of Molecular Genetics, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
35 Lysophosphatidic Acid-induced Mitogenesis Is Regulated by Lipid Phosphate Phosphatases and Is Edg-receptor Independent*
 

Summary:  of LPP-overexpressing cells was determined with an assay derived from the assay described above. HEK 293... cloned LPA receptors, we used a GTP S binding assay (22). Membranes from cells overexpressing the three... cells overexpressing LPP1 enzymes, resulting in a ...

  

Source: Santos, Webster L. - Department of Chemistry, Virginia Tech

 

Collection: Chemistry

 
36 LABELED EGFR-TK IRREVERSIBLE INHIBITOR (ML03): IN VITRO AND IN VIVO PROPERTIES, POTENTIAL AS PET BIOMARKER FOR CANCER AND
 

Summary:  A431 cells 8 hr post incuba- tion with the inhibitor. Specific binding (67%) of [11 C]ML03... was obtained in cells. An A431 tumor-bearing rat model was developed and the validity of the model was tested... -18 analytical column. BIOLOGICAL EVALUATION OF ML03 ...

  

Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem

 

Collection: Biology and Medicine

 
37 Molecular Cell 21, 319330, February 3, 2006 2006 Elsevier Inc. DOI 10.1016/j.molcel.2005.12.011 Mapping Pathways and Phenotypes
 

Summary:  to genes known to function in the mitotic cell cycle, we still find that overexpression of periodically... Molecular Cell 320 #12;for overexpression lethality. Rather, they are consistent with the primary mechanism... overexpressed in wt cells. However, ...

  

Source: Pál, Csaba - Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences

 

Collection: Biology and Medicine

 
38 Subunit S5a of the 26S proteasome is regulated by antiapoptotic signals
 

Summary:  to identify genes whose overexpression inhibits apoptosis of Saos-2 cells, induced by the Src inhibitor 4... experiments indicated that the overexpression of subunit S5a can rescue Saos-2 cells from PP1- induced... trans- formed with active Src (SrcNIH) and CSH12 cells, which are NIH3T3 ...

  

Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem

 

Collection: Biology and Medicine

 
39 Perspectives in Pharmacology Stoichiometry and Compartmentation in G Protein-Coupled
 

Summary:  and Benedetti EL (1989) Internalization of beta-adrenergic receptor in A431 cells involves non- coated vesicles... hearts. Overexpression of -AR subtypes or Gs in iso- lated cells or transgenic animals leads to small... activation or blockade of receptors. Human gene therapy, including ...

  

Source: Ostrom, Rennolds - Department of Pharmacology, University of Tennessee Health Science Center

 

Collection: Biology and Medicine

 
40 INTRODUCTION The four known members of the mammalian ErbB family of cell
 

Summary:  DER signalling was assessed in overexpression assays in the follicle cells and in the wing discs using... and not a homodimer, we obtained ventralized eggs after overexpressing a Kek1-Btl chimera in the follicle cells (data... . Eggs obtained after overexpressing UAS-kek1-DER in the ...

  

Source: Higgins, Darren - Department of Microbiology and Molecular Genetics, Harvard University

 

Collection: Biology and Medicine


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41 Using Liquid Crystals to Report Membrane Proteins Captured by Affinity Microcontact Printing from Cell Lysates and Membrane Extracts
 

Summary:  prepared from either human epidermoid carcinoma cells (A431), murine fibroblasts null for the EGFR (B82L... -EGFR (Cat # SC-03, Santa Cruz Biotech- nology) confirmed the presence of EGFR in A431 and B82L-WT cell... preparations and the absence of EGFR in B82L-parental ...

  

Source: Bertics, Paul J. - Molecular and Cellular Pharmacology Training Program & Department of Biomolecular Chemistry, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
42 Changes in the cytosolic concentra-tions of Ca2+
 

Summary:  mouse model. By contrast, overexpression of SPCA2 in a non- malignant mammary epithelial cell line, MCF... cells overexpressing SPCA2 reversed the tumorigenic abilities conferred by SPCA2 overexpression... in various human breast cancer cell lines and non-malignant ...

  

Source: Kenny, Paraic - Department of Developmental and Molecular Biology , Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
43 The Role of the Golgi Protein Golph3 in Type 2 Diabetes Suzette Farber-Katz
 

Summary:  : Determine if overexpression of Golph3 maintains beta cell survival and increases secretory capacity... . For that reason, I will test whether overexpression of Golph3 can promote both beta cell function and survival... . Experimental Design: Transgenic mice will be generated to ...

  

Source: Gleeson, Joseph G. - Department of Neurosciences, University of California at San Diego

 

Collection: Biology and Medicine

 
44 Evaluation of radiolabeled ML04, a putative irreversible inhibitor of epidermal growth factor receptor, as a bioprobe for PET imaging of
 

Summary:  and NCI-H1975 NSCLC cells, as previously described [41]. Briefly, A431 (1Â105 cells/well), MDA-MB-468 (3Â... cells: 2.8. Specific binding studies of [18 F]ML04 in intact A431 cells ...

  

Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem

 

Collection: Biology and Medicine

 
45 Transgenic Overexpression of the Transcription Factor Nkx6.1 in -Cells of Mice Does Not Increase
 

Summary:  Transgenic Overexpression of the Transcription Factor Nkx6.1 in -Cells of Mice Does Not Increase... , we sought to investigate whether overexpression of Nkx6.1 in -cells in vivo could increase -cell mass... -recom- binase-based transgenic model, we analyzed the effects of Nkx6.1 ...

  

Source: Sander, Maike - Departments of Pediatrics and Cellular and Molecular Medicine, University of California at San Diego

 

Collection: Biology and Medicine

 
46 Human cancers overexpress genes that are specific to a variety of normal human tissues
 

Summary:  in cancer cells but not in their normal counterparts and, thus, were overexpressed in the cancers... . The different cancer cell lines and leukemias varied in the number and identity of these overexpressed genes... . The results indicate that many genes that are overexpressed in human ...

  

Source: Domany, Eytan - Physics of Complex Systems, Weizmann Institute of Science

 

Collection: Biology and Medicine ; Physics

 
47 THEJOURNALOFCELLBIOLOGY The Rockefeller University Press $8.00
 

Summary:  by binding of EGF-QD. A431 cells express- ing endogenous erbB1 after incubation with 1 nM EGF-QD for 15 min... transport. (A) Ret- rograde transport of EGF-QD­erbB1s on filopodia of living A431 cells expressing en... OF ACTIVATED EGFR ON FILOPODIA · LIDKE ET AL. ...

  

Source: Rieger, Bernd - Department of Imaging, Science and Technology, Technische Universiteit Delft

 

Collection: Computer Technologies and Information Sciences ; Physics

 
48 Cell, Vol. 66, 497-505, August 9, 1991, Copyright 0 1991 by Cell Press Evidence for a Functional Link between
 

Summary:  . (1988). Regulation of epidermal growth factor-stimulated formation of inositol phosphates in A-431 cells... ). Antiphosphotyrosine recovery of phospholipase C activity after EGF treatment of A-431 cells. Science 247, 968... distribution are seen in ...

  

Source: Pollard, Thomas D.- Department of Molecular, Cellular and Developmental Biology, Yale University

 

Collection: Biology and Medicine

 
49 Identifying transcription factor functions and targets by phenotypic activation
 

Summary:  by cells overexpressing HMS1. Together, these results suggest that analysis of gene expression in organ... yeast TFs that caused a growth phenotype when overexpressed showed that the majority caused increased... organism with transgenic technology. microarray overexpression yeast Delineation of ...

  

Source: Frey, Brendan J. - Department of Electrical and Computer Engineering, University of Toronto; Morris, Quaid - Department of Electrical and Computer Engineering, University of Toronto

 

Collection: Computer Technologies and Information Sciences

 
50 Cell, Vol. 117, 253264, April 16, 2004, Copyright 2004 by Cell Press Negative Regulation of dE2F1 by Cyclin-Dependent
 

Summary:  animal and plant cells, overexpression the overall cell cycle duration (Neufeld et al., 1998). Like of G1... profiles of wing disc cells overexpressing GFP dacapo (dap), the fly homolog of human p21cip1 and alone (A... in G1 (Figure Cells expressing GFP only. (D and ...

  

Source: Gibson, Matt - Stowers Institute for Medical Research

 

Collection: Biology and Medicine

 
51 Short Report 1965 Introduction
 

Summary:  ­EGFP or in BSC1, A431 and HeLa cells immunolabeled for the endogenous Cav1 (pictures shown... with surface Cav1. (D)Internalization of CTBgold by metaphase A431 cells. CTBgold was internalized for 20... in metaphase A431 ...

  

Source: Kirchhausen, Tomas - Immune Disease Institute & Department of Cell Biology, Harvard University

 

Collection: Biology and Medicine

 
52 1339RESEARCH ARTICLE INTRODUCTION
 

Summary:  in these animals (Ober RESEARCH ARTICLE Development 138 (7) Fig. 1. Wnt8a overexpression induces liver cells... pronounced (Fig. 1F). It is also possible that in Wnt8a-overexpressing embryos, the increase of Prox1+ cells... ) and cell death using TUNEL assay in control and ...

  

Source: Hogan, Brigid L.M. - Department of Cell Biology, Duke University

 

Collection: Biology and Medicine

 
53 Role of the Heat Shock Response and Molecular Chaperones in Oncogenesis and Cell Death
 

Summary:  with the presence of the potent adenovirus trans- activator E1a (37­39); in contrast, in human A431 carcinoma cells... -transformed human embryonic kid- ney 293 cell line, overexpression of the endogenous Hsp70 gene is associated... ­48). Evidence to suggest a link between chaperones and ...

  

Source: Morimoto, Richard - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University

 

Collection: Biology and Medicine

 
54 INTRODUCTION The epidermal growth factor receptor (EGFR) is one of the
 

Summary:  cell A431 as a positive control because A431 cells possess a larger number of EGFRs on cell surface (up... to 106 per cell; Good et al., 1992; Wiley, 1988). Indeed A431 ...

  

Source: Oster, George - Department of Molecular and Cellular Biology, University of California at Berkeley

 

Collection: Biology and Medicine

 
55 Chaperone-dependent amyloid assembly protects cells from prion toxicity
 

Summary:  their conversion into benign or toxic amyloid-like species. Results Overexpression of Rnq1 Is Toxic in [RNQ ] Cells... overexpression, 25% of [RNQ ] cells were dead within 4 h, as determined by the percentage of colony-forming units... that toxicity positively correlated with the degree of ...

  

Source: Duennwald, Martin L. - Boston Biomedical Research Institute

 

Collection: Biology and Medicine

 
56 Accelerated Communication Selective Enhancement of -Adrenergic Receptor Signaling by
 

Summary:  cells and cells over- expressing AC6, AC6 overexpression enhanced responses to forskolin (10 M... .3% in control cells and 66 8.3% in cells overexpressing AC6 and forskolin- stimulated cAMP levels by 68 7... .1% in control cells and 74 7.3% in ...

  

Source: Ostrom, Rennolds - Department of Pharmacology, University of Tennessee Health Science Center

 

Collection: Biology and Medicine

 
57 BioMed Central Page 1 of 15
 

Summary:  cell divisions and reveals a compensatory mechanism during outer ovule integument morphogenesis Over-expression... in KNAT1 over-expressing lines (Figure 6A, B). Seed coat cell area sizes (n 25) of three seeds of three... KNAT1 over-express- ing lines were measured and compared to wild ...

  

Source: Haseloff, Jim - Department of Plant Sciences, University of Cambridge

 

Collection: Biology and Medicine

 
58 An inhibitor of the EGF receptor family blocks myeloma cell growth factor activity of HB-EGF and potentiates
 

Summary:  -16, XG-19) and one is an autonomously growing cell line (RPMI 8226). The A431 epidermoid carcinoma... expression, unlike ErbB4, was found in A431 cells (Figure 1A). ErbB2 was expressed in all cell lines and Erb... B3 in six out of nine ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
59 Modulation of the Suppressor of fused protein regulates the Hedgehog signaling pathway in Drosophila embryo and imaginal discs.
 

Summary:  independently of Hh signaling at the A/P border. All effects of Su(fu) over-expression, both in cells... , at the A/P border in cells receiving the Hh signal, overexpression of Su(fu) leads to a decrease... of cells overexpressing Su(fu) in wing and leg discs ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
60 i:S ~~~~~~~~~~~~~~~~~.a Cyclin-Dependent Regulation of G1
 

Summary:  that constitutively overexpress human cyclin E. This was found to shorten the duration of G1, decrease cell size... relative to the cells overexpressing cyclin E (0/51 = 0%). (B) Length of G1 in synchronized cells. Mitotic... S phase, the labeling intensity of cells ...

  

Source: Roberts, James M. - Basic Sciences Division, Fred Hutchinson Cancer Research Center

 

Collection: Biology and Medicine


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61 A model of planar polarity Supplementary material to "Cell interactions and planar
 

Summary:  Figure 2. Effect of a Fz overexpressing clone on the polarity of a wild-type automaton. Cells with normal... the overexpressing cells have an initial value greater than zero, more than one cell within the clone also shows... A model of planar polarity Supplementary material to ...

  

Source: Lawrence, Peter A. -Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine

 
62 RESEARCH ARTICLE Open Access Regulation of endocytic trafficking of transferrin
 

Summary:  have analyzed the effect of overexpression of the E50K and other mutants on survival of various cells... optineurin-overexpressing and con- trol cells. Western blot of the immunoprecipitate with ubiquitin antibody... R was immunoprecipitated from optineurin-overexpressing and control ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
63 STAM Adaptor Proteins Interact with COPII Complexes and Function in ER-to-Golgi Trafficking
 

Summary:  to early exocytic compartments and profoundly regulate Golgi morphology. Upon STAM overexpression in cells... on glutathione- Sepharose were incubated with lysates of HeLa cells overexpressing CFP-Sec31A, Sec13- YFP, GFP... and Sec13-YFP overexpressed in HeLa cells. ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
64 Molecular Biology of the Cell Vol. 17, 39403951, September 2006
 

Summary:  )-AT1 cells. Unexpectedly, Akt overexpression inhibits the AT1-mediated proliferation. This effect could... . As shown in Figure 1A (right), one representative cell line of this clone Figure 1. Akt overexpression... decreases cell prolif- eration induced by AngII. CHO-AT1A ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
65 Manifold anomalies in gene expression in a vineyard isolate of Saccharomyces cerevisiae revealed by
 

Summary:  of the overexpressed genes function in pathways of amino acid biosyn- thesis (particularly methionine) and sulfur... different conditions or at different stages of the cell cycle (4­8). Virtually nothing is known about... wine yeast is rarely found on grapes with an unbroken skin, viable cells are found in about one

  

Source: Hartl, Daniel L. - Department of Organismic and Evolutionary Biology, Harvard University

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
66 ScientificWorldJournal . Author manuscript Therapeutic antibodies for the treatment of pancreatic cancer
 

Summary:  - are often overexpressed by pancreatic cancer cells. Integrin 5 1 Integrins form a superfamily of widely... line A431) as large as 1.2 cm ( ). A phase II clinical trial comparing gemcitabine plus erlotinib... transduction pathways leading to cell growth and differentiation, and is ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
67 THE JOURNALOF BIOLOGICALCHEMISTRV 0 1993by The American Society for Biochemistry and Molecular Biology, Inc.
 

Summary:  .4 and SF3.2), overexpressing the a subtype of protein kinase C, and in two control cell lines (SC1 and SC2... in the twocell lines overexpressing protein kinaseC-a (7and 6 nM, in SF1.4 and SF3.2 cells, respectively) thanin... the response to phorbol esters incontrol (SC1) cells but not ...

  

Source: Wurtman, Richard - Department of Brain and Cognitive Science, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
68 Calpain Inhibition Decreases the Growth Rate of Mammalian Cell Colonies*
 

Summary:  for this discrepancy, Chinese ham- ster ovary cell lines were established that overexpress the calpain inhibitor... culture plates. However, when cells were plated at higher density, calpastatin overexpression had no influ... a decreased amount of 1 kb mRNA in cells ...

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
69 Papers of the Week Expand Your Nuclear Horizons
 

Summary:  Papers of the Week Expand Your Nuclear Horizons A cell nucleus undergoes dramatic structural... changes during the cell cycle, which require extensive remodeling of the nuclear membrane. How this remod... and colleagues found that overexpressing DKG1 re- sulted in membranes enriched in phosphatidic acid

  

Source: Chen, Kuang-Yu - Department of Chemistry and Chemical Biology, Rutgers University

 

Collection: Biology and Medicine ; Chemistry

 
70 2652 Research Article Introduction
 

Summary:  -type cells and overexpressing cells containing the clone with the highest productivity (clone 17), the levels... .001) (Fig. 1B). The increase of cathepsin X activity in overexpressing cells (Fig. 1C) was visualised... -X- overexpressing cells ...

  

Source: Bogyo, Matthew - Department of Microbiology and Immunology, Stanford University

 

Collection: Biology and Medicine

 
71 Alexander Shekhtman Department of Chemistry
 

Summary:  overexpression of Ubiquitin and STAM2 in yeast cells to perform STINT-NMR experiments. 3) Extend STINT... Award: $1,228,768 Dates: July 1, 2010 ­ June 30, 2015 In-cell NMR technology to study protein... complexes caused by aberrant posttranslational modifications (PTM). We propose to develop a novel in-cell

  

Source: Knuth, Kevin H. - Department of Physics, State University of New York at Albany

 

Collection: Physics

 
72 Overexpression of RelA Causes G1 Arrest and Apoptosis in a Pro-B Cell Line*
 

Summary:  Overexpression of RelA Causes G1 Arrest and Apoptosis in a Pro-B Cell Line* (Received... and transactivation domains of RelA were required for this effect. When RelA was overexpressed in the immature B cell... the individual effects of either RelA or c-Rel overexpression in a pro-B ...

  

Source: Schlissel, Mark S. - Department of Molecular and Cell Biology, University of California at Berkeley

 

Collection: Biology and Medicine

 
73 Cancer Res. Author manuscript Cyclin-dependent kinase 2/cyclin E complex is involved in p120 catenin
 

Summary:  . Overexpression of the p120ctn isoform 3A in human colon adenocarcinoma cells (HT-29) results in cytoplasmic... is required for centrosome duplication ( ).15 Cyclin E overexpression in human cancer cells increases... of p120ctn after overexpression in HT-29 cells ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
74 Genome Biology 2004, 5:216 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch
 

Summary:  and overexpression of oncogenes [9,10]. In addition, the manipulated cells also expressed green fluorescent protein... clones of cells that are mutant for a gene of interest and that #12;simultaneously overexpress one... . In addition, deletion of warts does not phenocopy scrib deletion in ...

  

Source: Kango-Singh, Madhuri - Department of Biology, University of Dayton

 

Collection: Biology and Medicine

 
75 Neurobiology of Disease Torsin-Mediated Protection from Cellular Stress in the
 

Summary:  losing neuronal cell bodies (68.9 and 58.9% of wild-type neurons conferred by overexpression of torsin... , Immunolocalization of torsinA in torsinA( E302/303)-overexpressing worms in CEP cell bodies (arrows). Scale bar, 20 m... A and torsinA( E302/303) using anti-torsinA antibody in CEP ...

  

Source: Caldwell, Guy - Department of Biological Sciences, University of Alabama in Tuscaloosa

 

Collection: Biology and Medicine

 
76 Cyclin-Dependent Kinase 2/Cyclin E Complex Is Involved in p120 Catenin (p120ctn)Dependent Cell Growth Control: A New Role for p120ctn in Cancer
 

Summary:  progression. Overexpression of the p120ctn isoform 3A in human colon adenocarcinoma cells (HT-29) results... is required for centrosome duplication (15). Cyclin E overexpression in human cancer cells increases... .05. Results Cytoplasmic localization of p120ctn after overexpression in ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
77 This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon.
 

Summary:  expressed in transfected HeLa cells (Additional file 1). Overexpression and knockdown of Six3 and Six3OS... to cells electroporated with the GFP control vector at P21 (Figure 3A). Since Six3OS overexpression did... the effects of Six3 overexpression. No differences in the composition of ...

  

Source: Blackshaw, Seth - Department of Neuroscience, Johns Hopkins University

 

Collection: Biology and Medicine

 
78 Published in IET Systems Biology Received on 3rd December 2007
 

Summary:  , based upon constitutive oligomerisation estimates (14%) in A431 cells that overexpress EGFR.Q1 When... in oligomers when A431 cells were treated with antibodies that block ligand binding. We began our study... . Their study focused on the ...

  

Source: Steinberg, Stanly - Department of Mathematics and Statistics, University of New Mexico

 

Collection: Mathematics

 
79 DOI: 10.1126/science.1200215 , 1207 (2011);331Science
 

Summary:  DOI: 10.1126/science.1200215 , 1207 (2011);331Science , et al.Reut Shema in the NeocortexOverexpression... M+ (Fig. 4G) memory cells after challenge. Thus, IgM+ memory cells were not intrinsically hypore- sponsive... challenge by plasma cells or after challenge by memory cell­derived ...

  

Source: Dudai, Yadin - Department of Neurobiology, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
80 Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells.
 

Summary:  (respectively, five- and eightfold less than the A431 carcinoma cell line known to produce EGF-family ligands... = CT ­ CT 2m) and compared to A431 (for AREG and HB-EGF) or XG-7 cells (for ErbB receptor genes) used... overexpressed AREG compared ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics


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81 Tight JunctionAssociated Signaling Pathways Modulate Cell Proliferation in Uveal Melanoma
 

Summary:  . METHODS. Human uveal melanoma cell lines overexpressing the TJ molecule blood vessel epicardial substance... (Bves) were generated. The effects of Bves overexpression on TJ protein expression, cell proliferation... -associated pathways. RESULTS. Bves overexpression in uveal melanoma ...

  

Source: Vanderbilt University, Department of Biomedical Engineering, Laboratory for Bionanotechnology and Nanomedicine

 

Collection: Biology and Medicine

 
82 Involvement of KU80 in T-DNA integration in plant cells
 

Summary:  - entiation of transformed or wild-type cells. KU80 overexpression resulted in larger tumors, but not callus... Involvement of KU80 in T-DNA integration in plant cells Jianxiong Li*, Manjusha Vaidya*, Charles... White , Alexander Vainstein , Vitaly Citovsky*, and Tzvi Tzfira*§ *Department of Biochemistry and ...

  

Source: Citovsky, Vitaly - Department of Biochemistry and Cell Biology, SUNY at Stony Brook

 

Collection: Biology and Medicine ; Biotechnology

 
83 ORIGINAL ARTICLE Overexpression of antizyme-inhibitor in NIH3T3 fibroblasts provides
 

Summary:  show here that overexpression of AzI in NIH3T3 cells increased growth rate, enabled growth in low serum... study, we directly examined the effect of AzI overexpression on cell proliferation and trans- formation... it as a potential target for cancer therapy. Results Overexpression of AzI ...

  

Source: Kahana, Chaim - Department of Molecular Genetics, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
84 Fortgeschrittenenpraktikum Entwicklungsbiologie im WS Modul A: Experimentelle Embryologie / Entwicklungsgenetik Zebrafische 1 Woche
 

Summary:  zebrafish development, live observation cell cleavage, cell movement (Epiboly, Gastrulation) and axis... embryos by cell transplantation of cells at blastoderm stage - Analysis using fluorescence and confocal... microscopy 6 Molecular embryology: Manipulating axis formation and early patterning by gene ...

  

Source: 

 

Collection: Physics ; Mathematics ; Biotechnology

 
85 Cellular/Molecular Acetylation of Microtubules Influences Their Sensitivity
 

Summary:  tissue culture fibroblasts (Piperno et al., 1987). In HDAC6- overexpressing cells, we observed notable... to select the most highly overexpressing cells to visualize the notable re- duction in acetylation, so from... overexpression and tubacin treatment on cellular microtubule ...

  

Source: Baas, Peter W. - Department of Neurobiology and Anatomy, Drexel University

 

Collection: Biology and Medicine

 
86 Niemann-Pick Type C1 (NPC1) Overexpression Alters Cellular Cholesterol Homeostasis*
 

Summary:  - nese hamster ovary (CHO) cell lines overexpressing the human NPC1 protein (CHO/NPC1). NPC1 overexpres... of NPC1, we generated stable Chinese hamster ovary (CHO) cell lines that overexpress NPC1 and examined... . M. Traub, J. E. Schaffer, and D. S. Ory, unpublished results. NPC1 ...

  

Source: Traub, Linton M. - Department of Cell Biology and Physiology, University of Pittsburgh

 

Collection: Biology and Medicine

 
87 High-Affinity Epidermal Growth Factor Receptor (EGFR) Irreversible Inhibitors with Diminished Chemical Reactivities as Positron Emission
 

Summary:  Cell Lysates as an EGFR Source. A431 human epidermoid vulval carcinoma cells, which overexpress... performed with A431 cell lysates (human epidermoid vulval carcinoma cells), which over- express the ...

  

Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem

 

Collection: Biology and Medicine

 
88 Embryonic stem cell markers expression in cancers Matthieu Schoenhals
 

Summary:  ) cells. In conjunction with Klf4 and c-Myc, their over-expression can induce pluripotency in both mouse... -Myc are expressed in embryonic stem (ES) cells, and their over-expression can induce pluripotency in both mouse... also act as an oncogene [26]. It is overexpressed in laryngeal ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
89 This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research
 

Summary:  the controls. Arsenic uptake was also evaluated in cells overexpressing the transporters coupled with high... accumulation was evaluated in a resting S. cerevisiae cell system after overexpression of the As... and HXT7 overexpression Exposing growing cells to high ...

  

Source: Chen, Wilfred - Department of Chemical and Environmental Engineering, University of California at Riverside

 

Collection: Biotechnology ; Environmental Management and Restoration Technologies

 
90 Cutaneous Overexpression of Neurotrophin-3 (NT3) Selectively Restores Sensory Innervation In NT3
 

Summary:  of Merkel cells and SAI type neurons that occurred in the heterozy- gous knockout genotype. Overexpression... overexpression on Mer- kel cells was determined by injecting mice with quin- acrine dihydrochloride... , but not to overexpresser levels (p < .05). Control K14-NT3 NT3 / ...

  

Source: Krimm, Robin - Department of Anatomical Sciences and Neurobiology, University of Louisville

 

Collection: Biology and Medicine

 
91 INTRODUCTION The development of axons and dendrites is critical for the
 

Summary:  the formation of cell processes and that this effect is blocked by the overexpression of dynamitin. Our results... process formation in non-neuronal cells Fig. 1 shows the effect of overexpression of ac... activity. For this purpose, we simultaneously overexpressed ac.CaP-RFP and ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
92 Vascular Biology, Atherosclerosis and Endothelium Biology Overexpression of Bcl-2 in Vascular Endothelium
 

Summary:  or leukostasis. There- fore, overexpression of Bcl-2 in endothelial cells inhibits the capillary degeneration... . Overexpression of Bcl-2 in Endothelium 2551 AJP May 2010, Vol. 176, No. 5 #12;counts of apoptotic cells... . Mice Overexpressing Bcl-2 in Endothelial ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
93 Neuron, Vol. 17, 2741, July, 1996, Copyright 1996 by Cell Press Control of Daughter Cell Fates during Asymmetric
 

Summary:  and #12;Neuron 28 overexpression of numb results in reciprocal cell fate Ghysen et al., 1993), the role... 3B). As expected from such a cell fate trans- 1993) and studied the effect of overexpression... stained cells in approximately 90% of the segmentsOverexpression ...

  

Source: Guo, Ming - Brain Research Institute, University of California at Los Angeles

 

Collection: Biology and Medicine

 
94 Computational Model of Vascular Endothelial Growth Factor Spatial Distribution in Muscle
 

Summary:  gradients for the overexpression models directly affect cell surface receptor VEGF binding. For single... -Angiogenic Cell Therapy Feilim Mac Gabhann* , James W. Ji, Aleksander S. Popel Department of Biomedical... matrix; binding to and activation of endothelial cell surface VEGF receptors; and ...

  

Source: Popel, Aleksander S. - Department of Biomedical Engineering, Johns Hopkins University

 

Collection: Engineering ; Biology and Medicine

 
95 ANTIOXIDANTS & REDOX SIGNALING Volume 3, Number 3, 2001
 

Summary:  -a, or H2O2 treatment of MCF-7 cells. Findings from these studies demonstrate that GPx-1 overexpression can... activation. Overexpression of GPx-1 in MCF-7 cells reduces NFkB activity Having determined the parameters... Ad.BlgII infected cells) was subtracted from all experimentally ...

  

Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa

 

Collection: Biology and Medicine

 
96 Proc. Natl. Acad. Sci. USA Vol. 95, pp. 91559160, August 1998
 

Summary:  . Furthermore, in cultured cells, SC35 overexpression increases apoptosis; whereas heterogeneous nuclear... generates two products, Ich-1L and Ich-1S. Ich-1L induces cell death; whereas overexpression of Ich-1S... overexpression is known to induce apoptosis in these ...

  

Source: Wu, Jane Y. - Center for Genetic Medicine & Department of Neurology, Northwestern University

 

Collection: Biology and Medicine

 
97 Molecular Biology of the Cell Vol. 19, 14851498, April 2008
 

Summary:  of the Cell1490 #12;rat RFL-6 fibroblasts in which we overexpressed each of the two severing proteins... 60-katanin­ overexpressing cells showed a mixture of short and long microtubules (Figure 8B... ). In sharp contrast, the spastin- overexpressing cells displayed a ...

  

Source: Baas, Peter W. - Department of Neurobiology and Anatomy, Drexel University

 

Collection: Biology and Medicine

 
98 bcl-2 Overexpression Eliminates Deprivation-Induced Cell Death of Brainstem Auditory Neurons
 

Summary:  bcl-2 Overexpression Eliminates Deprivation-Induced Cell Death of Brainstem Auditory Neurons Sam P... of deafferen- tation, whereas bcl-2-overexpressing mice do not. This suggests that bcl-2 can influence cell... neurons to deafferentation-induced cell death Transgenic mice ...

  

Source: Rubel, Edwin - Department of Physiology and Biophysics, University of Washington at Seattle

 

Collection: Biology and Medicine

 
99 APRIL is overexpressed in cancer: link with tumor progression
 

Summary:  cells (P = 2E-6)[33]. Four independent studies have shown BAFF overexpression in glioblastoma compared... with the recruitment of antibody-secreting cells[39]. The overexpression of BAFF in brain tumors could be linked... male germ cell tumor compared to normal testis (Korkola et al[43]; ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
100 Targeted synthetic gene delivery vectors David V Schaffer1
 

Summary:  that overexpress certain integrins. Growth factor receptors are another class of cell surface proteins with promise... membrane translocation and DNA-binding domains to target a reporter gene containing polyplex to A431 tumor... cells overexpressing the EGFR [20]. ...

  

Source: Long, Jeffrey R.- Department of Chemistry, University of California at Berkeley

 

Collection: Materials Science ; Chemistry


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