Behavioral effects of radioprotective agents in mice: Combination of WR-2721 and 16,16 dimethyl prostaglandin E2
Technical Report
·
OSTI ID:5681195
Although the radioprotective properties of a number of compounds have been investigated in the last 40 years the consideration and testing of the behavioral effects of these agents has only recently begun to be systematically investigated. Behavioral toxicity of an agent ha enhances radiotherapeutic efficacy is not necessarily a limiting factor in clinical use where small numbers of patients can be monitored and treated. However, an effective drug-screening program for radio protective agents must evaluate the behavioral toxicity of those compounds that have potential use for humans in radiation accidents and in civil defense situations.
- Research Organization:
- Armed Forces Radiobiology Research Inst., Bethesda, MD (USA)
- OSTI ID:
- 5681195
- Report Number(s):
- AD-A-231137/1/XAB; AFFRI-SR-90-34
- Resource Relation:
- Other Information: Pub. in Frontiers in Radiation Biology, p199-207 1990
- Country of Publication:
- United States
- Language:
- English
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PROSTAGLANDINS
RADIOSENSITIVITY EFFECTS
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560152* - Radiation Effects on Animals- Animals
PROSTAGLANDINS
RADIOSENSITIVITY EFFECTS
RADIOPROTECTIVE SUBSTANCES
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BEHAVIOR
CIVIL DEFENSE
MICE
ANIMALS
DRUGS
MAMMALS
NATIONAL DEFENSE
RODENTS
VERTEBRATES
560152* - Radiation Effects on Animals- Animals