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Title STUDIES ON THE EFFECT OF $sup 60$Co GAMMA IRRADIATION ON THE GOAT. I. CHANGES IN BLOOD CONSTITUENTS FOLLOWING 1,000 r TOTAL BODY GAMMA IRRADIATION
Creator/Author Hayashi, M. ; Miyao, N.
Publication Date1961 Jan 01
OSTI IdentifierOSTI ID: 4808158
Resource TypeJournal Article
Resource RelationJournal Name: Natl. Inst. Animal Health Quart. (Tokyo); Journal Volume: Vol: 1; Other Information: Orig. Receipt Date: 31-DEC-62
Research OrgOriginating Research Org. not identified
SubjectBIOLOGY AND MEDICINE; ANIMALS; BIOCHEMISTRY; BLOOD PLASMA; BODY; COBALT 60; ERYTHROCYTES; GAMMA RADIATION; GOATS; LEUCOCYTES; LIFETIME; LIPIDS; NITROGEN; NUCLEIC ACIDS; PHOSPHORUS; PROTEINS; QUANTITY RATIO; RADIATION DOSES; RADIATION EFFECTS; RIBONUCLEIC ACID; WEIGHT
Description/AbstractGoats were irradiated with a dose of 1,000 r of Co/sup 60/ gamma rays. Changes in blood constituents before and after exposure were compared between these goats, and non-irradiated controls, both of which were forced to fast during the same period. All irradiated goats died in about 10 days after irradiation. Loss in body weight was of the same extent in irradiated goats as in controls. Leukocyte counts remained unchanged for a short time after exposure, began to decrease sharply on the next day, and were reduced below 1,000 cells per mm/sup 3/ around the 3rd day postirradiation. Erythrocyte counts were not decreased, but increased immediately following exposure and, in some irradiated goats, also terminally. The blood sugar showed a tendency to increase in the irradiated group but decreased slightiy in the control. The plasma protein exhibited a slight decrease around the first or second day postirradiation. Plasma nonprotein nitrogen showed a tendency to decrease. The amino nitrogen level in the plasma was scarcely changed. Plasma inorganic phosphorus appeared to increase in the fasting irradiated group. After exposure, the lipid phosphorus decreased markedly until the terminal period, when it increased slightly. This finding in the goat was quite different from that in other animals. Ribonucleic acid phosphorus, desoxyribonucleic acid phosphorus, and phosphoprotein phosphorus decreased from a comparatively early period after exposure. (auth)
Country of PublicationCountry unknown/Code not available
LanguageEnglish
FormatMedium: X; Size: Pages: 215-24
System Entry Date2009 Dec 15

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