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DOI http://dx.doi.org/10.1016/0020-708X(59)90188-7
Title THE ROLE OF THE RETICULOENDOTHELIAL PHAGOCYTOSIS IN THE IRRADIATED MULTICELLULAR ORGANISM. I. EXAMINATION OF THE REMOTE ACTION OF RADIOTOXINS BY MEANS OF PARABIOTIC TECHNIQUES
Creator/Author Ludwig, F.
Publication Date1959 Jan 01
OSTI IdentifierOSTI ID: 4294590
Resource TypeJournal Article
Resource RelationJournal Name: Intern. J. Appl. Radiation and Isotopes; Journal Volume: Vol: 4; Other Information: Orig. Receipt Date: 31-DEC-59
Research OrgCommissariat a l'Energie Atomique, Saclay, France
SubjectBIOLOGY AND MEDICINE; BLOOD; BLOOD CIRCULATION; CARBON; DUSTS; LYMPH SYSTEM; PARABIOSIS; PHAGOCYTOSIS; RADIATION EFFECTS; RADIOTOXINS; RATS; RETICULOENDOTHELIAL SYSTEM; TOXICITY; TUMORS
Description/AbstractAfter one single irradiation the activity of the radiotoxins, as followed by an abscopal effect produced in an ascites tumor, is progressively reduced. Furthermore, by introduction of carbon particles in the bloodstream of parabiotically united rats, it is possible to achieve an partner, after previous irradiation of the other animal. Such injections of chemically inert granular systems in the blood stream of experimental animals reduce temporarily the granulopectic activity of the reticuloendothelial system and aggravate pathological conditions involving phagocytosis. We therefore conclude that ap preciable fractions of the radiotoxins are neutralized by the reticuloendothelial system. (auth)
Country of PublicationCountry unknown/Code not available
LanguageFrench
FormatMedium: X; Size: Pages: 162-8
System Entry Date2009 Dec 14

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