DOE Patents Database - Search Results

Patent Title	Inventor(s)	Issue Date	Patent Number
Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted. Variant Humicola grisea CBH1.1	Goedegebuur, Frits , Gualfetti, Peter , Mitchinson, Colin , Larenas, Edmund	12/02/2008	7,459,299
Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted. Variant Humicola grisea CBH1.1	Goedegebuur, Frits , Gualfetti, Peter , Mitchinson, Colin , Larenas, Edmund	05/31/2011	7951571
Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted. CBH1 homologs and variant CBH1 cellulases	Goedegebuur, Frits , Gualfetti, Peter , Mitchinson, Colin , Neefe, Paulien	05/31/2011	7951570
Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted. Variant Humicola grisea CBH1.1	Goedegebuur, Frits , Gualfetti, Peter , Mitchinson, Colin , Larenas, Edmund	08/16/2011	7,998,711
The present invention relates to a heterologous exo-endo cellulase fusion construct, which encodes a fusion protein having cellulolytic activity comprising a catalytic domain derived from a fungal exo-cellobiohydrolase and a catalytic domain derived from an endoglucanase. The invention also relates to vectors and fungal host cells comprising the heterologous exo-endo cellulase fusion construct as well as methods for producing a cellulase fusion protein and enzymatic cellulase compositions. Exo-endo cellulase fusion protein	Bower, Benjamin S. , Larenas, Edmund A. , Mitchinson, Colin	01/17/2012	8,097,445
Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted. Variant Humicola grisea CBH1.1	Goedegebuur, Frits , Gualfetti, Peter , Mitchinson, Colin , Larenas, Edmund	08/07/2012	8,236,546
Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted. CBH1 homologs and variant CBH1 cellulases	Goedegebuur, Frits , Gualfetti, Peter , Mitchinson, Colin , Neefe, Paulien	11/18/2008	7,452,707
Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility. Variant Hypocrea jecorina CBH1 cellulases	Day, Anthony , Goedegebuur, Frits , Gualfetti, Peter , Mitchinson, Colin , Neefe, Paulien , Sandgren, Mats , Shaw, Andrew , Stahlberg, Jerry	07/05/2011	7,972,832
Described herein are variants of H. jecorina CBH2, a Cel6A enzyme. The present invention provides novel cellobiohydrolases that have altered thermostability. Variant Hypocrea jecorina CBH2 cellulases	Aehle, Wolfgang , Goedegebuur, Frits , Dankmeyer, Lydia , Mitchinson, Colin , Neefe, Paulien , Kelemen, Brad , Caldwell, Robert , Teunissen, Pauline	08/30/2011	8,008,056
Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility. Variant Hyprocrea jecorina CBH1 cellulases	Day, Anthony , Goedegebuur, Frits , Gualfetti, Peter , Mitchinson, Colin , Neefe, Paulien , Sandgren, Mats , Shaw, Andrew , Stahlberg, Jerry	07/31/2012	8,232,080