Bibliographic Citation
| 8,232,058 | |
| Multiplex detection of respiratory pathogens Loading...
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| 07/31/2012 | |
| US patent application 12/161,291 | |
| McBride, Mary (Brentwood, CA); Slezak, Thomas (Livermore, CA); Birch, James M. (Albany, CA) | |
| Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States) | |
| USDOE | |
| W-7405-ENG-48 | |
| Lawrence Livermore National Security, LLC (Livermore, CA) | |
| Described are kits and methods useful for detection of respiratory pathogens (influenza A (including subtyping capability for H1, H3, H5 and H7 subtypes) influenza B, parainfluenza (type 2), respiratory syncytial virus, and adenovirus) in a sample. Genomic sequence information from the respiratory pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay to successfully identify the presence or absence of pathogens in a sample. | |
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