Bibliographic Citation

 
8,189,186
Signal enhancement using a switchable magnetic trap
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05/29/2012
US patent application 11/965,598
Beer, Neil Reginald (Pleasanton, CA)
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
USDOE
AC52-07NA27344
Lawrence Livermore National Security, LLC. (Livermore, CA)
A system for analyzing a sample including providing a microchannel flow channel; associating the sample with magnetic nanoparticles or magnetic polystyrene-coated beads; moving the sample with said magnetic nanoparticles or magnetic polystyrene-coated beads in the microchannel flow channel; holding the sample with the magnetic nanoparticles or magnetic polystyrene-coated beads in a magnetic trap in the microchannel flow channel; and analyzing the sample obtaining an enhanced analysis signal. An apparatus for analysis of a sample includes magnetic particles connected to the sample, a microchip, a flow channel in the microchip, a source of carrier fluid connected to the flow channel for moving the sample in the flow channel, an electromagnet trap connected to the flow line for selectively magnetically trapping the sample and the magnetic particles, and an analyzer for analyzing the sample.

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