Planar micromixer
Abstract
The present embodiment describes a laminar-mixing embodiment that utilizes simple, three-dimensional injection. Also described is the use of the embodiment in combination with wide and shallow sections of channel to affect rapid mixing in microanalytical systems. The shallow channel sections are constructed using all planar micromachining techniques, including those based on isotropic etching. The planar construction enables design using minimum dispersion concepts that, in turn, enable simultaneous mixing and injection into subsequent chromatography channels.
- Inventors:
-
- Bethesda, MD
- Danville, CA
- Alpharetta, GA
- Issue Date:
- Research Org.:
- Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 927907
- Patent Number(s):
- 7344681
- Application Number:
- 10/960,324
- Assignee:
- Sandia Corporation (Livermore, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Fiechtner, Gregory J, Singh, Anup K, and Wiedenman, Boyd J. Planar micromixer. United States: N. p., 2008.
Web.
Fiechtner, Gregory J, Singh, Anup K, & Wiedenman, Boyd J. Planar micromixer. United States.
Fiechtner, Gregory J, Singh, Anup K, and Wiedenman, Boyd J. Tue .
"Planar micromixer". United States. https://www.osti.gov/servlets/purl/927907.
@article{osti_927907,
title = {Planar micromixer},
author = {Fiechtner, Gregory J and Singh, Anup K and Wiedenman, Boyd J},
abstractNote = {The present embodiment describes a laminar-mixing embodiment that utilizes simple, three-dimensional injection. Also described is the use of the embodiment in combination with wide and shallow sections of channel to affect rapid mixing in microanalytical systems. The shallow channel sections are constructed using all planar micromachining techniques, including those based on isotropic etching. The planar construction enables design using minimum dispersion concepts that, in turn, enable simultaneous mixing and injection into subsequent chromatography channels.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 18 00:00:00 EDT 2008},
month = {Tue Mar 18 00:00:00 EDT 2008}
}
Works referenced in this record:
Multiple injection techniques for microfluidic sample handling
journal, September 2003
- Fu, Lung-Ming; Yang, Ruey-Jen; Lee, Gwo-Bin
- ELECTROPHORESIS, Vol. 24, Issue 17
Electrophoresis using ultra-high voltages
journal, November 2002
- Vazquez, Maribel; McKinley, Gareth; Mitnik, Luba
- Journal of Chromatography B, Vol. 779, Issue 2
Low-Dispersion Turns and Junctions for Microchannel Systems
journal, January 2001
- Griffiths, Stewart K.; Nilson, Robert H.
- Analytical Chemistry, Vol. 73, Issue 2
Faceted Design of Channels for Low-Dispersion Electrokinetic Flows in Microfluidic Systems
journal, September 2003
- Fiechtner, Gregory J.; Cummings, Eric B.
- Analytical Chemistry, Vol. 75, Issue 18
Development of a microfluidic device for fluorescence activated cell sorting
journal, June 2002
- Kr$uuml$ger, Jan; Singh, Kirat; O$apos$Neill, Alan
- Journal of Micromechanics and Microengineering, Vol. 12, Issue 4
Microfluidic chips for clinical and forensic analysis
journal, March 2002
- Verpoorte, Elisabeth
- ELECTROPHORESIS, Vol. 23, Issue 5, p. 677-712
Passive mixing in a three-dimensional serpentine microchannel
journal, June 2000
- Liu, R. H.; Stremler, M. A.; Sharp, K. V.
- Journal of Microelectromechanical Systems, Vol. 9, Issue 2
Electrokinetic Injection Techniques in Microfluidic Chips
journal, October 2002
- Fu, L. -M.; Yang, R. -J.; Lee, G. -B.
- Analytical Chemistry, Vol. 74, Issue 19
Numerical Analysis and Experimental Estimation of a Low-Leakage Injection Technique for Capillary Electrophoresis
journal, November 2003
- Fu, Lung-Ming; Lin, Che-Hsin
- Analytical Chemistry, Vol. 75, Issue 21
Continuous separation of biomolecules by the laterally asymmetric diffusion array with out-of-plane sample injection
journal, October 2002
- Cabodi, Mario; Chen, Yi-Fan; Turner, Stephen W. P.
- ELECTROPHORESIS, Vol. 23, Issue 20, p. 3496-3503
A Chaotic Electroosmotic Stirrer
journal, August 2002
- Qian, Shizhi; Bau, Haim H.
- Analytical Chemistry, Vol. 74, Issue 15
Electrokinetic Instability Micromixing
journal, December 2001
- Oddy, M. H.; Santiago, J. G.; Mikkelsen, J. C.
- Analytical Chemistry, Vol. 73, Issue 24
A Picoliter-Volume Mixer for Microfluidic Analytical Systems
journal, May 2001
- He, Bing; Burke, Brian J.; Zhang, Xiang
- Analytical Chemistry, Vol. 73, Issue 9
Microfluidic separation of DNA
journal, October 2003
- Ashton, Randolph; Padala, Chakradhar; Kane, Ravi S.
- Current Opinion in Biotechnology, Vol. 14, Issue 5
Microchip Structures for Submillisecond Electrophoresis
journal, August 1998
- Jacobson, Stephen C.; Culbertson, Christopher T.; Daler, Justin E.
- Analytical Chemistry, Vol. 70, Issue 16
Design and optimization of on-chip capillary electrophoresis
journal, August 2002
- Bharadwaj, Rajiv; Santiago, Juan G.; Mohammadi, Bijan
- ELECTROPHORESIS, Vol. 23, Issue 16, p. 2729-2744
Microchannel Flow with Patchwise and Periodic Surface Heterogeneity
journal, November 2002
- Erickson, David; Li, Dongqing
- Langmuir, Vol. 18, Issue 23
Effects of Injection Schemes and Column Geometry on the Performance of Microchip Electrophoresis Devices
journal, April 1994
- Jacobson, Stephen C.; Hergenroder, Roland.; Koutny, Lance B.
- Analytical Chemistry, Vol. 66, Issue 7
Patterning Electro-osmotic Flow with Patterned Surface Charge
journal, April 2000
- Stroock, Abraham D.; Weck, Marcus; Chiu, Daniel T.
- Physical Review Letters, Vol. 84, Issue 15
Micromachining of capillary electrophoresis injectors and separators on glass chips and evaluation of flow at capillary intersections
journal, January 1994
- Fan, Zhonghui H.; Harrison, D. Jed.
- Analytical Chemistry, Vol. 66, Issue 1
Injection of Sample Bands from open Channels Into Packed Separation Columns
book, January 2002
- Nilson, Robert H.; Griffiths, Stewart K.; Singh, Anup K.
- Micro Total Analysis Systems 2002
Mixing Processes in a Zigzag Microchannel: Finite Element Simulations and Optical Study
journal, August 2002
- Mengeaud, Virginie; Josserand, Jacques; Girault, Hubert H.
- Analytical Chemistry, Vol. 74, Issue 16
Low-dispersion electrokinetic flows for expanded separation channels in microfluidic systems:
journal, February 2004
- Fiechtner, Gregory J.; Cummings, Eric B.
- Journal of Chromatography A, Vol. 1027, Issue 1-2