Synthesis of isotopically labeled R- or S-[.sup.13C, .sup.2H] glycerols
Abstract
The present invention is directed to asymmetric chiral labeled glycerols including at least one chiral atom, from one to two .sup.13C atoms and from zero to four deuterium atoms bonded directly to a carbon atom, e.g., (2S) [1,2-.sup.13C.sub.2]glycerol and (2R) [1,2-.sup.13C.sub.2]glycerol, and to the use of such chiral glycerols in the preparation of labeled amino acids.
- Inventors:
-
- Santa Fe, NM
- Los Alamos, NM
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 927842
- Patent Number(s):
- 7321070
- Application Number:
- 10/629,982
- Assignee:
- Los Alamos National Security, LLC (Los Alamos, NM)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07B - GENERAL METHODS OF ORGANIC CHEMISTRY
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
- DOE Contract Number:
- W-7405-ENG-36
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Martinez, Rodolfo A, Unkefer, Clifford J, and Alvarez, Marc A. Synthesis of isotopically labeled R- or S-[.sup.13C, .sup.2H] glycerols. United States: N. p., 2008.
Web.
Martinez, Rodolfo A, Unkefer, Clifford J, & Alvarez, Marc A. Synthesis of isotopically labeled R- or S-[.sup.13C, .sup.2H] glycerols. United States.
Martinez, Rodolfo A, Unkefer, Clifford J, and Alvarez, Marc A. Tue .
"Synthesis of isotopically labeled R- or S-[.sup.13C, .sup.2H] glycerols". United States. https://www.osti.gov/servlets/purl/927842.
@article{osti_927842,
title = {Synthesis of isotopically labeled R- or S-[.sup.13C, .sup.2H] glycerols},
author = {Martinez, Rodolfo A and Unkefer, Clifford J and Alvarez, Marc A},
abstractNote = {The present invention is directed to asymmetric chiral labeled glycerols including at least one chiral atom, from one to two .sup.13C atoms and from zero to four deuterium atoms bonded directly to a carbon atom, e.g., (2S) [1,2-.sup.13C.sub.2]glycerol and (2R) [1,2-.sup.13C.sub.2]glycerol, and to the use of such chiral glycerols in the preparation of labeled amino acids.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jan 22 00:00:00 EST 2008},
month = {Tue Jan 22 00:00:00 EST 2008}
}
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