Cell density signal protein suitable for treatment of connective tissue injuries and defects
Abstract
Identification, isolation and partial sequencing of a cell density protein produced by fibroblastic cells. The cell density signal protein comprising a 14 amino acid peptide or a fragment, variant, mutant or analog thereof, the deduced cDNA sequence from the 14 amino acid peptide, a recombinant protein, protein and peptide-specific antibodies, and the use of the peptide and peptide-specific antibodies as therapeutic agents for regulation of cell differentiation and proliferation. A method for treatment and repair of connective tissue and tendon injuries, collagen deficiency, and connective tissue defects.
- Inventors:
-
- Oakland, CA
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
- OSTI Identifier:
- 874652
- Patent Number(s):
- 6433136
- Application Number:
- 09/215184
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
- DOE Contract Number:
- AC03-76SF00098
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- cell; density; signal; protein; treatment; connective; tissue; injuries; defects; identification; isolation; partial; sequencing; produced; fibroblastic; cells; comprising; 14; amino; acid; peptide; fragment; variant; mutant; analog; deduced; cdna; sequence; recombinant; peptide-specific; antibodies; therapeutic; agents; regulation; differentiation; proliferation; method; repair; tendon; collagen; deficiency; amino acid; dna sequence; /530/
Citation Formats
Schwarz, Richard I. Cell density signal protein suitable for treatment of connective tissue injuries and defects. United States: N. p., 2002.
Web.
Schwarz, Richard I. Cell density signal protein suitable for treatment of connective tissue injuries and defects. United States.
Schwarz, Richard I. Tue .
"Cell density signal protein suitable for treatment of connective tissue injuries and defects". United States. https://www.osti.gov/servlets/purl/874652.
@article{osti_874652,
title = {Cell density signal protein suitable for treatment of connective tissue injuries and defects},
author = {Schwarz, Richard I},
abstractNote = {Identification, isolation and partial sequencing of a cell density protein produced by fibroblastic cells. The cell density signal protein comprising a 14 amino acid peptide or a fragment, variant, mutant or analog thereof, the deduced cDNA sequence from the 14 amino acid peptide, a recombinant protein, protein and peptide-specific antibodies, and the use of the peptide and peptide-specific antibodies as therapeutic agents for regulation of cell differentiation and proliferation. A method for treatment and repair of connective tissue and tendon injuries, collagen deficiency, and connective tissue defects.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jan 01 00:00:00 EST 2002},
month = {Tue Jan 01 00:00:00 EST 2002}
}
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