Preparation of 2-hydroxy-5-oxoproline and analogs thereof
Abstract
The compound 2-hydroxy-5-oxoproline and analogs thereof may be used to produce an increase in carbon dioxide fixation, growth, dry weight, nutritional value (proteins and amino acids), nodulation and nitrogen fixation and photosynthetically derived chemical energy when applied to plants through their roots and/or through their foliar portions. The present invention includes an essentially quantitative chemical synthesis for this compound which is performed in a single step reaction of Fremy's Salt (potassium nitrosodisulphonate) with either glutamine or 2-pyrrolidone-5-carboxylic acid. Fremy's salt (potassium nitrosodisulphonate) is available commercially, or can be readily synthesized.
- Inventors:
-
- Santa Fe, NM
- Los Alamos, NM
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- OSTI Identifier:
- 873985
- Patent Number(s):
- 6288240
- Assignee:
- Regents of University of California (Los Alamos, NM)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS
- DOE Contract Number:
- W-7405-ENG-36
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- preparation; 2-hydroxy-5-oxoproline; analogs; compound; produce; increase; carbon; dioxide; fixation; growth; dry; weight; nutritional; value; proteins; amino; acids; nodulation; nitrogen; photosynthetically; derived; chemical; energy; applied; plants; roots; foliar; portions; essentially; quantitative; synthesis; performed; single; step; reaction; fremy; salt; potassium; nitrosodisulphonate; glutamine; 2-pyrrolidone-5-carboxylic; acid; available; commercially; readily; synthesized; chemical synthesis; dry weight; nitrogen fixation; single step; chemical energy; amino acid; carbon dioxide; carboxylic acid; amino acids; step reaction; /999/
Citation Formats
Martinez, Rodolfo A, and Unkefer, Pat J. Preparation of 2-hydroxy-5-oxoproline and analogs thereof. United States: N. p., 2001.
Web.
Martinez, Rodolfo A, & Unkefer, Pat J. Preparation of 2-hydroxy-5-oxoproline and analogs thereof. United States.
Martinez, Rodolfo A, and Unkefer, Pat J. Mon .
"Preparation of 2-hydroxy-5-oxoproline and analogs thereof". United States. https://www.osti.gov/servlets/purl/873985.
@article{osti_873985,
title = {Preparation of 2-hydroxy-5-oxoproline and analogs thereof},
author = {Martinez, Rodolfo A and Unkefer, Pat J},
abstractNote = {The compound 2-hydroxy-5-oxoproline and analogs thereof may be used to produce an increase in carbon dioxide fixation, growth, dry weight, nutritional value (proteins and amino acids), nodulation and nitrogen fixation and photosynthetically derived chemical energy when applied to plants through their roots and/or through their foliar portions. The present invention includes an essentially quantitative chemical synthesis for this compound which is performed in a single step reaction of Fremy's Salt (potassium nitrosodisulphonate) with either glutamine or 2-pyrrolidone-5-carboxylic acid. Fremy's salt (potassium nitrosodisulphonate) is available commercially, or can be readily synthesized.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 2001},
month = {Mon Jan 01 00:00:00 EST 2001}
}
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