Baculovirus expression system and method for high throughput expression of genetic material
Abstract
The present invention provides novel recombinant baculovirus expression systems for expressing foreign genetic material in a host cell. Such expression systems are readily adapted to an automated method for expression foreign genetic material in a high throughput manner. In other aspects, the present invention features a novel automated method for determining the function of foreign genetic material by transfecting the same into a host by way of the recombinant baculovirus expression systems according to the present invention.
- Inventors:
-
- Benecia, CA
- Mill Valley, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- OSTI Identifier:
- 873700
- Patent Number(s):
- 6225060
- Assignee:
- Onyx Pharmaceuticals, Inc. (Richmond, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- baculovirus; expression; method; throughput; genetic; material; provides; novel; recombinant; systems; expressing; foreign; host; cell; readily; adapted; automated; manner; aspects; features; determining; function; transfecting; according; expression systems; automated method; genetic material; provides novel; host cell; baculovirus expression; /435/999/
Citation Formats
Clark, Robin, and Davies, Anthony. Baculovirus expression system and method for high throughput expression of genetic material. United States: N. p., 2001.
Web.
Clark, Robin, & Davies, Anthony. Baculovirus expression system and method for high throughput expression of genetic material. United States.
Clark, Robin, and Davies, Anthony. Mon .
"Baculovirus expression system and method for high throughput expression of genetic material". United States. https://www.osti.gov/servlets/purl/873700.
@article{osti_873700,
title = {Baculovirus expression system and method for high throughput expression of genetic material},
author = {Clark, Robin and Davies, Anthony},
abstractNote = {The present invention provides novel recombinant baculovirus expression systems for expressing foreign genetic material in a host cell. Such expression systems are readily adapted to an automated method for expression foreign genetic material in a high throughput manner. In other aspects, the present invention features a novel automated method for determining the function of foreign genetic material by transfecting the same into a host by way of the recombinant baculovirus expression systems according to the present invention.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 2001},
month = {Mon Jan 01 00:00:00 EST 2001}
}
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The 35-kilodalton protein gene ( p35 ) of Autographa californica nuclear polyhedrosis virus and the neomycin resistance gene provide dominant selection of recombinant baculoviruses
journal, January 1993
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Production and purification of novel secreted human proteins
journal, January 1997
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