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Title: Multispectral imaging method and apparatus

Abstract

A multispectral imaging method and apparatus adapted for use in determining material properties, especially properties characteristic of abnormal non-dermal cells. A target is illuminated with a narrow band light beam. The target expresses light in response to the excitation. The expressed light is collected and the target's response at specific response wavelengths to specific excitation wavelengths is measured. From the measured multispectral response the target's properties can be determined. A sealed, remote probe and robust components can be used for cervical imaging

Inventors:
 [1];  [2];  [2];  [3];  [4];  [5]
  1. Moriarty, NM
  2. Albuquerque, NM
  3. Lorain, OH
  4. Tucson, AZ
  5. Austin, TX
Issue Date:
Research Org.:
Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
OSTI Identifier:
872373
Patent Number(s):
5920399
Assignee:
Sandia Corporation (Albuquerque, NM)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
G - PHYSICS G01 - MEASURING G01J - MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
multispectral; imaging; method; apparatus; adapted; determining; material; properties; especially; characteristic; abnormal; non-dermal; cells; target; illuminated; narrow; band; light; beam; expresses; response; excitation; expressed; collected; specific; wavelengths; measured; determined; sealed; remote; probe; robust; components; cervical; multispectral imaging; apparatus adapted; light beam; material properties; narrow band; imaging method; expressed light; band light; determining material; /356/250/600/

Citation Formats

Sandison, David R, Platzbecker, Mark R, Vargo, Timothy D, Lockhart, Randal R, Descour, Michael R, and Richards-Kortum, Rebecca. Multispectral imaging method and apparatus. United States: N. p., 1999. Web.
Sandison, David R, Platzbecker, Mark R, Vargo, Timothy D, Lockhart, Randal R, Descour, Michael R, & Richards-Kortum, Rebecca. Multispectral imaging method and apparatus. United States.
Sandison, David R, Platzbecker, Mark R, Vargo, Timothy D, Lockhart, Randal R, Descour, Michael R, and Richards-Kortum, Rebecca. Fri . "Multispectral imaging method and apparatus". United States. https://www.osti.gov/servlets/purl/872373.
@article{osti_872373,
title = {Multispectral imaging method and apparatus},
author = {Sandison, David R and Platzbecker, Mark R and Vargo, Timothy D and Lockhart, Randal R and Descour, Michael R and Richards-Kortum, Rebecca},
abstractNote = {A multispectral imaging method and apparatus adapted for use in determining material properties, especially properties characteristic of abnormal non-dermal cells. A target is illuminated with a narrow band light beam. The target expresses light in response to the excitation. The expressed light is collected and the target's response at specific response wavelengths to specific excitation wavelengths is measured. From the measured multispectral response the target's properties can be determined. A sealed, remote probe and robust components can be used for cervical imaging},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Fri Jan 01 00:00:00 EST 1999},
month = {Fri Jan 01 00:00:00 EST 1999}
}

Works referenced in this record:

In vivo diagnosis of cervical intraepithelial neoplasia using 337-nm-excited laser-induced fluorescence.
journal, October 1994


Study of the fluorescence properties of normal and neoplastic human cervical tissue
journal, January 1993