Antibody-mediated reduction of .alpha.-ketoamides
Abstract
Monoclonal antibodies raised against a 4-nitrophenyl phosphonate hapten catalyze the stereospecific reduction of an .alpha.-ketoamide to the corresponding .alpha.-hydroxyamide in the presence of an appropriate reducing agent.
- Inventors:
-
- Oakland, CA
- East Palo Alto, CA
- Issue Date:
- Research Org.:
- Univ. of California (United States)
- OSTI Identifier:
- 871609
- Patent Number(s):
- 5763249
- Assignee:
- Regents of University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- AC03-76SF00098
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- antibody-mediated; reduction; alpha; -ketoamides; monoclonal; antibodies; raised; 4-nitrophenyl; phosphonate; hapten; catalyze; stereospecific; -ketoamide; corresponding; -hydroxyamide; presence; appropriate; reducing; agent; reducing agent; monoclonal antibodies; /435/530/
Citation Formats
Schultz, Peter G, and Gallop, Mark A. Antibody-mediated reduction of .alpha.-ketoamides. United States: N. p., 1998.
Web.
Schultz, Peter G, & Gallop, Mark A. Antibody-mediated reduction of .alpha.-ketoamides. United States.
Schultz, Peter G, and Gallop, Mark A. Thu .
"Antibody-mediated reduction of .alpha.-ketoamides". United States. https://www.osti.gov/servlets/purl/871609.
@article{osti_871609,
title = {Antibody-mediated reduction of .alpha.-ketoamides},
author = {Schultz, Peter G and Gallop, Mark A},
abstractNote = {Monoclonal antibodies raised against a 4-nitrophenyl phosphonate hapten catalyze the stereospecific reduction of an .alpha.-ketoamide to the corresponding .alpha.-hydroxyamide in the presence of an appropriate reducing agent.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Thu Jan 01 00:00:00 EST 1998},
month = {Thu Jan 01 00:00:00 EST 1998}
}