Reduction of diffusional defocusing in hydrodynamically focused flows
Abstract
An analyte fluid stream with first molecules having relatively low molecular weight and a corresponding high coefficient of diffusion has reduced diffusional defocusing out of an analyte fluid stream. The analyte fluid stream of first molecules is associated with second molecules of relatively high molecular weight having a relatively low coefficient of diffusion and a binding constant effective to associate with the first molecules. A focused analyte fluid stream is maintained since the combined molecular weight of the associated first and second molecules is effective to minimize diffusion of the first molecules out of the analyte fluid stream. 6 figs.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California (United States)
- Sponsoring Org.:
- USDOE, Washington, DC (United States)
- OSTI Identifier:
- 672656
- Patent Number(s):
- 5799682
- Application Number:
- PAN: 8-758,738
- Assignee:
- Univ. of California, Los Alamos, NM (United States)
- DOE Contract Number:
- W-7405-ENG-36
- Resource Type:
- Patent
- Resource Relation:
- Other Information: PBD: 1 Sep 1998
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 40 CHEMISTRY; CHEMICAL ANALYSIS; LIQUIDS; MOLECULAR WEIGHT; DIFFUSION; MITIGATION; ADSORPTION; FLUID FLOW; SAMPLE PREPARATION
Citation Formats
Affleck, R L, Demas, J N, Goodwin, P M, Keller, R, and Wu, M. Reduction of diffusional defocusing in hydrodynamically focused flows. United States: N. p., 1998.
Web.
Affleck, R L, Demas, J N, Goodwin, P M, Keller, R, & Wu, M. Reduction of diffusional defocusing in hydrodynamically focused flows. United States.
Affleck, R L, Demas, J N, Goodwin, P M, Keller, R, and Wu, M. Tue .
"Reduction of diffusional defocusing in hydrodynamically focused flows". United States.
@article{osti_672656,
title = {Reduction of diffusional defocusing in hydrodynamically focused flows},
author = {Affleck, R L and Demas, J N and Goodwin, P M and Keller, R and Wu, M},
abstractNote = {An analyte fluid stream with first molecules having relatively low molecular weight and a corresponding high coefficient of diffusion has reduced diffusional defocusing out of an analyte fluid stream. The analyte fluid stream of first molecules is associated with second molecules of relatively high molecular weight having a relatively low coefficient of diffusion and a binding constant effective to associate with the first molecules. A focused analyte fluid stream is maintained since the combined molecular weight of the associated first and second molecules is effective to minimize diffusion of the first molecules out of the analyte fluid stream. 6 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Sep 01 00:00:00 EDT 1998},
month = {Tue Sep 01 00:00:00 EDT 1998}
}
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