Implantable apparatus for localized heating of tissue
Abstract
With the object of repetitively treating deep-seated, inoperable tumors by hyperthermia as well as locally heating other internal tissue masses repetitively, a receiving antenna, transmission line and electrode arrangement are implanted completely within the patient's body, with the receiving antenna just under the surface of the skin and with the electrode arrangement being located so as to most effectively heat the tissue to be treated. An external, transmitting antenna, driven by an external radio-frequency energy source, is closely coupled to the implanted receiving antenna so that the energy coupled across the air-skin interface provides electromagnetic energy suitable for heating the tissue in the vicinity of the implanted electrodes. The resulting increase in tissue temperature may be estimated by an indirect measurement of the decrease in tissue resistivity in the heat region. This change in resistivity appears as a change in the loading of the receiving antenna which can be measured by either determining the change in the phase relationship between the voltage and the current appearing on the transmitting antenna or by measuring the change in the magnitude of the impedance thereof. Optionally, multiple electrode arrays may be activated or inactivated by the application of magnetic fields to operate implantedmore »
- Inventors:
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- OSTI Identifier:
- 5650360
- Application Number:
- ON: DE86013716
- Assignee:
- Dept. of Energy
- DOE Contract Number:
- W-7405-ENG-36
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; HEATERS; DESIGN; IMPLANTS; MEDICAL SUPPLIES; MICROWAVE EQUIPMENT; HYPERTHERMIA; NEOPLASMS; BODY TEMPERATURE; DISEASES; ELECTRONIC EQUIPMENT; EQUIPMENT; 560206* - Thermal Effects- Man- (-1987); 550600 - Medicine
Citation Formats
Doss, J D. Implantable apparatus for localized heating of tissue. United States: N. p., 1985.
Web.
Doss, J D. Implantable apparatus for localized heating of tissue. United States.
Doss, J D. Mon .
"Implantable apparatus for localized heating of tissue". United States.
@article{osti_5650360,
title = {Implantable apparatus for localized heating of tissue},
author = {Doss, J D},
abstractNote = {With the object of repetitively treating deep-seated, inoperable tumors by hyperthermia as well as locally heating other internal tissue masses repetitively, a receiving antenna, transmission line and electrode arrangement are implanted completely within the patient's body, with the receiving antenna just under the surface of the skin and with the electrode arrangement being located so as to most effectively heat the tissue to be treated. An external, transmitting antenna, driven by an external radio-frequency energy source, is closely coupled to the implanted receiving antenna so that the energy coupled across the air-skin interface provides electromagnetic energy suitable for heating the tissue in the vicinity of the implanted electrodes. The resulting increase in tissue temperature may be estimated by an indirect measurement of the decrease in tissue resistivity in the heat region. This change in resistivity appears as a change in the loading of the receiving antenna which can be measured by either determining the change in the phase relationship between the voltage and the current appearing on the transmitting antenna or by measuring the change in the magnitude of the impedance thereof. Optionally, multiple electrode arrays may be activated or inactivated by the application of magnetic fields to operate implanted magnetic reed swtiches. 5 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon May 20 00:00:00 EDT 1985},
month = {Mon May 20 00:00:00 EDT 1985}
}