Probes labelled with energy transfer coupled dyes
Abstract
Compositions are provided comprising sets of fluorescent labels carrying pairs of donor and acceptor dye molecules, designed for efficient excitation of the donors at a single wavelength and emission from the acceptor in each of the pairs at different wavelengths. The different molecules having different donor-acceptor pairs can be modified to have substantially the same mobility under separation conditions, by varying the distance between the donor and acceptor in a given pair. Particularly, the fluorescent compositions find use as labels in sequencing nucleic acids. 7 figs.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California (United States)
- Sponsoring Org.:
- USDOE, Washington, DC (United States)
- OSTI Identifier:
- 563688
- Patent Number(s):
- 5688648
- Application Number:
- PAN: 8-574,890
- Assignee:
- Univ. of California, Oakland, CA (United States)
- DOE Contract Number:
- FG03-91ER61125
- Resource Type:
- Patent
- Resource Relation:
- Other Information: PBD: 18 Nov 1997
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 55 BIOLOGY AND MEDICINE, BASIC STUDIES; DNA SEQUENCERS; DNA SEQUENCING; DESIGN; FLUORESCENCE; DNA; MOLECULAR BIOLOGY
Citation Formats
Mathies, R A, Glazer, A, and Ju, J. Probes labelled with energy transfer coupled dyes. United States: N. p., 1997.
Web.
Mathies, R A, Glazer, A, & Ju, J. Probes labelled with energy transfer coupled dyes. United States.
Mathies, R A, Glazer, A, and Ju, J. Tue .
"Probes labelled with energy transfer coupled dyes". United States.
@article{osti_563688,
title = {Probes labelled with energy transfer coupled dyes},
author = {Mathies, R A and Glazer, A and Ju, J},
abstractNote = {Compositions are provided comprising sets of fluorescent labels carrying pairs of donor and acceptor dye molecules, designed for efficient excitation of the donors at a single wavelength and emission from the acceptor in each of the pairs at different wavelengths. The different molecules having different donor-acceptor pairs can be modified to have substantially the same mobility under separation conditions, by varying the distance between the donor and acceptor in a given pair. Particularly, the fluorescent compositions find use as labels in sequencing nucleic acids. 7 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Nov 18 00:00:00 EST 1997},
month = {Tue Nov 18 00:00:00 EST 1997}
}
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