Restoration of normal phenotype in cancer cells
Abstract
A method for reversing expression of malignant phenotype in cancer cells is described. The method comprises applying {beta}{sub 1} integrin function-blocking antibody to the cells. The method can be used to assess the progress of cancer therapy. Human breast epithelial cells were shown to be particularly responsive. 14 figs.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California (United States)
- Sponsoring Org.:
- USDOE, Washington, DC (United States)
- OSTI Identifier:
- 321195
- Patent Number(s):
- 5846536
- Application Number:
- PAN: 8-726,230
- Assignee:
- Univ. of California, Oakland, CA (United States)
- DOE Contract Number:
- AC03-76SF00098
- Resource Type:
- Patent
- Resource Relation:
- Other Information: PBD: 8 Dec 1998
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 55 BIOLOGY AND MEDICINE, BASIC STUDIES; NEOPLASMS; PHENOTYPE; ANTIBODIES; MAMMARY GLANDS; TUMOR CELLS; EPITHELIUM; WOMEN
Citation Formats
Bissell, M J, and Weaver, V M. Restoration of normal phenotype in cancer cells. United States: N. p., 1998.
Web.
Bissell, M J, & Weaver, V M. Restoration of normal phenotype in cancer cells. United States.
Bissell, M J, and Weaver, V M. Tue .
"Restoration of normal phenotype in cancer cells". United States.
@article{osti_321195,
title = {Restoration of normal phenotype in cancer cells},
author = {Bissell, M J and Weaver, V M},
abstractNote = {A method for reversing expression of malignant phenotype in cancer cells is described. The method comprises applying {beta}{sub 1} integrin function-blocking antibody to the cells. The method can be used to assess the progress of cancer therapy. Human breast epithelial cells were shown to be particularly responsive. 14 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Dec 08 00:00:00 EST 1998},
month = {Tue Dec 08 00:00:00 EST 1998}
}
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