Method for palliation of pain in human bone cancer using therapeutic tin-117m compositions
Abstract
The invention provides a method for the palliation of bone pain due to cancer by the administration of a unique dosage of a tin-117m (Sn-117m) stannic chelate complex in a pharmaceutically acceptable composition. In addition, the invention provides a method for simultaneous palliation of bone pain and radiotherapy in cancer patients using compositions containing Sn-117m chelates. The invention also provides a method for palliating bone pain in cancer patients using Sn-117m-containing compositions and monitoring patient status by imaging the distribution of the Sn-117m in the patients. Also provided are pharmaceutically acceptable compositions containing Sn-117m chelate complexes for the palliation of bone pain in cancer patients. 5 figs.
- Inventors:
- Issue Date:
- Research Org.:
- Associated Universities Inc
- Sponsoring Org.:
- USDOE, Washington, DC (United States)
- OSTI Identifier:
- 321189
- Patent Number(s):
- 5853695
- Application Number:
- PAN: 8-743,287; TRN: 99:003295
- Assignee:
- Brookhaven Science Associates LLC, Upton, NY (United States)
- DOE Contract Number:
- AC02-76CH00016
- Resource Type:
- Patent
- Resource Relation:
- Other Information: PBD: 29 Dec 1998
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 55 BIOLOGY AND MEDICINE, BASIC STUDIES; TIN 117; ISOMERIC NUCLEI; RADIOTHERAPY; SKELETON; PAIN; NEOPLASMS; RADIOPHARMACEUTICALS; THERAPEUTIC USES
Citation Formats
Srivastava, S C, Meinken, G E, Mausner, L F, and Atkins, H L. Method for palliation of pain in human bone cancer using therapeutic tin-117m compositions. United States: N. p., 1998.
Web.
Srivastava, S C, Meinken, G E, Mausner, L F, & Atkins, H L. Method for palliation of pain in human bone cancer using therapeutic tin-117m compositions. United States.
Srivastava, S C, Meinken, G E, Mausner, L F, and Atkins, H L. Tue .
"Method for palliation of pain in human bone cancer using therapeutic tin-117m compositions". United States.
@article{osti_321189,
title = {Method for palliation of pain in human bone cancer using therapeutic tin-117m compositions},
author = {Srivastava, S C and Meinken, G E and Mausner, L F and Atkins, H L},
abstractNote = {The invention provides a method for the palliation of bone pain due to cancer by the administration of a unique dosage of a tin-117m (Sn-117m) stannic chelate complex in a pharmaceutically acceptable composition. In addition, the invention provides a method for simultaneous palliation of bone pain and radiotherapy in cancer patients using compositions containing Sn-117m chelates. The invention also provides a method for palliating bone pain in cancer patients using Sn-117m-containing compositions and monitoring patient status by imaging the distribution of the Sn-117m in the patients. Also provided are pharmaceutically acceptable compositions containing Sn-117m chelate complexes for the palliation of bone pain in cancer patients. 5 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Dec 29 00:00:00 EST 1998},
month = {Tue Dec 29 00:00:00 EST 1998}
}