System, emanation generator, and process for production of high-purity therapeutic radioisotopes
Abstract
An isotope production system, emanation generator, and process are disclosed for production of high-purity radioisotopes. In one implementation example, high-purity Pb-212 and/or Bi-212 isotopes are produced suitable for therapeutic applications. In one embodiment the process includes transporting gaseous radon-220 from a radium-224 bearing generator which provides gas-phase separation of the Rn-220 from the Ra-224 in the generator. Subsequent decay of the captured Rn-220 accumulates high-purity Pb-212 and/or Bi-212 isotopes suitable for direct therapeutic applications. Other high-purity product isotopes may also be prepared.
- Inventors:
- Issue Date:
- Research Org.:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1892995
- Patent Number(s):
- 11348702
- Application Number:
- 15/675,529
- Assignee:
- Battelle Memorial Institute (Richland, WA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
- DOE Contract Number:
- AC05-76RL01830
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 08/11/2017
- Country of Publication:
- United States
- Language:
- English
Citation Formats
O'Hara, Matthew J. System, emanation generator, and process for production of high-purity therapeutic radioisotopes. United States: N. p., 2022.
Web.
O'Hara, Matthew J. System, emanation generator, and process for production of high-purity therapeutic radioisotopes. United States.
O'Hara, Matthew J. Tue .
"System, emanation generator, and process for production of high-purity therapeutic radioisotopes". United States. https://www.osti.gov/servlets/purl/1892995.
@article{osti_1892995,
title = {System, emanation generator, and process for production of high-purity therapeutic radioisotopes},
author = {O'Hara, Matthew J.},
abstractNote = {An isotope production system, emanation generator, and process are disclosed for production of high-purity radioisotopes. In one implementation example, high-purity Pb-212 and/or Bi-212 isotopes are produced suitable for therapeutic applications. In one embodiment the process includes transporting gaseous radon-220 from a radium-224 bearing generator which provides gas-phase separation of the Rn-220 from the Ra-224 in the generator. Subsequent decay of the captured Rn-220 accumulates high-purity Pb-212 and/or Bi-212 isotopes suitable for direct therapeutic applications. Other high-purity product isotopes may also be prepared.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue May 31 00:00:00 EDT 2022},
month = {Tue May 31 00:00:00 EDT 2022}
}
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