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Title: Electrochemical flow-cell for hydrogen production and nicotinamide dependent target reduction, and related methods and systems

Abstract

Methods and systems for hydrogen production or production of a reduced target molecule are described, wherein a nicotinamide co-factor dependent membrane hydrogenase or a nicotinamide co-factor dependent membrane enzyme presented on a nanolipoprotein adsorbed onto an electrically conductive supporting structure, which can preferably be chemically inert, is contacted with protons or a target molecule to be reduced and nicotinamide cofactors in presence of an electric current and one or more electrically driven redox mediators. Methods and systems for production of hydrogen or a reduced target molecule are also described wherein a membrane-bound hydrogenase enzyme or enzyme capable or reducing a target molecule is contacted with protons or the target molecule, a nicotinamide co-factor and a nicotinamide co-factor dependent membrane hydrogenase presented on a nanolipoprotein particle for a time and under condition to allow hydrogen production or production of a reduced target molecule in presence of an electrical current and of an electrically driven redox mediator.

Inventors:
;
Issue Date:
Research Org.:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1805572
Patent Number(s):
10934628
Application Number:
16/167,384
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C25 - ELECTROLYTIC OR ELECTROPHORETIC PROCESSES C25B - ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Patent
Resource Relation:
Patent File Date: 10/22/2018
Country of Publication:
United States
Language:
English

Citation Formats

Hoeprich, Jr., Paul D., and Kim, Sangil. Electrochemical flow-cell for hydrogen production and nicotinamide dependent target reduction, and related methods and systems. United States: N. p., 2021. Web.
Hoeprich, Jr., Paul D., & Kim, Sangil. Electrochemical flow-cell for hydrogen production and nicotinamide dependent target reduction, and related methods and systems. United States.
Hoeprich, Jr., Paul D., and Kim, Sangil. Tue . "Electrochemical flow-cell for hydrogen production and nicotinamide dependent target reduction, and related methods and systems". United States. https://www.osti.gov/servlets/purl/1805572.
@article{osti_1805572,
title = {Electrochemical flow-cell for hydrogen production and nicotinamide dependent target reduction, and related methods and systems},
author = {Hoeprich, Jr., Paul D. and Kim, Sangil},
abstractNote = {Methods and systems for hydrogen production or production of a reduced target molecule are described, wherein a nicotinamide co-factor dependent membrane hydrogenase or a nicotinamide co-factor dependent membrane enzyme presented on a nanolipoprotein adsorbed onto an electrically conductive supporting structure, which can preferably be chemically inert, is contacted with protons or a target molecule to be reduced and nicotinamide cofactors in presence of an electric current and one or more electrically driven redox mediators. Methods and systems for production of hydrogen or a reduced target molecule are also described wherein a membrane-bound hydrogenase enzyme or enzyme capable or reducing a target molecule is contacted with protons or the target molecule, a nicotinamide co-factor and a nicotinamide co-factor dependent membrane hydrogenase presented on a nanolipoprotein particle for a time and under condition to allow hydrogen production or production of a reduced target molecule in presence of an electrical current and of an electrically driven redox mediator.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 02 00:00:00 EST 2021},
month = {Tue Mar 02 00:00:00 EST 2021}
}

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