Methods for making and processing metal targets for producing Cu-67 radioisotope for medical applications
Abstract
The present invention provides a method for producing Cu67 radioisotope suitable for use in medical applications. The method comprises irradiating a metallic zinc-68 (Zn68) target with a high energy gamma ray beam. After irradiation, the Cu67 is isolated from the Zn68 by any suitable method (e.g., chemical and/or physical separation). In a preferred embodiment, the Cu67 is isolated by sublimation of the zinc (e.g., at about 500-700° C. under reduced pressure) to afford a copper residue containing Cu67. The Cu67 can be further purified by chemical means (i.e., dissolution in acid, followed by ion exchange).
- Inventors:
- Issue Date:
- Research Org.:
- Argonne National Laboratory (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1531870
- Patent Number(s):
- 8526561
- Application Number:
- 12/462,099
- Assignee:
- UChicago Argonne, LLC (Chicago, IL)
- Patent Classifications (CPCs):
-
G - PHYSICS G21 - NUCLEAR PHYSICS G21K - TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR
- DOE Contract Number:
- AC02-06CH11357; W-31-109-ENG-38
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2009-07-29
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 62 RADIOLOGY AND NUCLEAR MEDICINE; 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; 07 ISOTOPE AND RADIATION SOURCES
Citation Formats
Ehst, David A., and Bowers, Delbert L. Methods for making and processing metal targets for producing Cu-67 radioisotope for medical applications. United States: N. p., 2013.
Web.
Ehst, David A., & Bowers, Delbert L. Methods for making and processing metal targets for producing Cu-67 radioisotope for medical applications. United States.
Ehst, David A., and Bowers, Delbert L. Tue .
"Methods for making and processing metal targets for producing Cu-67 radioisotope for medical applications". United States. https://www.osti.gov/servlets/purl/1531870.
@article{osti_1531870,
title = {Methods for making and processing metal targets for producing Cu-67 radioisotope for medical applications},
author = {Ehst, David A. and Bowers, Delbert L.},
abstractNote = {The present invention provides a method for producing Cu67 radioisotope suitable for use in medical applications. The method comprises irradiating a metallic zinc-68 (Zn68) target with a high energy gamma ray beam. After irradiation, the Cu67 is isolated from the Zn68 by any suitable method (e.g., chemical and/or physical separation). In a preferred embodiment, the Cu67 is isolated by sublimation of the zinc (e.g., at about 500-700° C. under reduced pressure) to afford a copper residue containing Cu67. The Cu67 can be further purified by chemical means (i.e., dissolution in acid, followed by ion exchange).},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Sep 03 00:00:00 EDT 2013},
month = {Tue Sep 03 00:00:00 EDT 2013}
}
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Works referenced in this record:
Production of radioisotopes with a high specific activity by isotopic conversion
patent, September 1999
- Lidsky, Lawrence M.; Lanza, Richard C.
- US Patent Document 5,949,836
Production of high specific activity copper-67
patent-application, January 2003
- Jamriska, SR., David J.; Taylor, Wayne A.; Ott, Martin A.
- US Patent Application 10/246960; 20030016775
Process for extraction of metals from ores or industrial materials
patent-application, February 2006
- Holgersen, James D.
- US Patent Application 11/252843; 20060037438
Production of no-carrier added 67Cu
journal, January 1986
- Mirzadeh, S.; Mausner, L. F.; Srivastava, S. C.
- International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, Vol. 37, Issue 1, p. 29-36
Production of radioisotopes with a high specific activity by isotopic conversion
patent, March 2001
- Lidsky, Lawrence M.; Lanza, Richard C.
- US Patent Document 6,208,704
Polymer beads containing an immobilized extractant for sorbing metals from solution
patent, January 1994
- Jeffers, Thomas H.; Seidel, Don C.
- US Patent Document 5,279,745
The production of copper 67 from natural zinc using a linear accelerator
journal, November 1970
- Marceau, N.; Kruck, T. P. A.; McConnell, D. B.
- The International Journal of Applied Radiation and Isotopes, Vol. 21, Issue 11, p. 667-669
The Preparation of High Specific Activity Copper 64
journal, January 1964
- Fritze, K.
- Radiochimica Acta, Vol. 3, Issue 3
Electron Acceleration beyond 200 MeV in Underdense Plasmas using Table Top Laser Systems
conference, January 2002
- Fritzler, S.
- ADVANCED ACCELERATOR CONCEPTS: Tenth Workshop, AIP Conference Proceedings
Method of producing molybdenum-99
patent, July 1998
- Lidsky, Lawrence M.; Lanza, Richard C.
- US Patent Document 5,784,423
Chemical modification of silica surface by immobilization of functional groups for extractive concentration of metal ions
journal, April 2004
- Jal, P.
- Talanta, Vol. 62, Issue 5
Works referencing / citing this record:
Production of copper-67 from an enriched zinc-68 target
patent, June 2018
- Stoner, Jon; Gardner, Tim
- US Patent Document 10,006,101