Recombinant yeast having enhanced gamma valerolactone tolerance and methods of use
Abstract
The present invention relates to materials and methods for the production of ethanol. More particularly, the present invention provides genetically modified strains of Saccharomyces cerevisiae having enhanced tolerance for gamma valerolactone (GVL) toxicity. Also provided are methods of using such genetically engineered yeast strains for improved GVL-mediated hydrolysis of lignocellulosic biomass for industrial-scale ethanol production.
- Inventors:
- Issue Date:
- Research Org.:
- Wisconsin Alumni Research Foundation, Madison, WI (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1460543
- Patent Number(s):
- 10006057
- Application Number:
- 14/848,440
- Assignee:
- Wisconsin Alumni Research Foundation (Madison, WI)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
- DOE Contract Number:
- FC02-07ER64494
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2015 Sep 09
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Piotrowski, Jeff S., Sato, Trey K., and Myers, Chad L. Recombinant yeast having enhanced gamma valerolactone tolerance and methods of use. United States: N. p., 2018.
Web.
Piotrowski, Jeff S., Sato, Trey K., & Myers, Chad L. Recombinant yeast having enhanced gamma valerolactone tolerance and methods of use. United States.
Piotrowski, Jeff S., Sato, Trey K., and Myers, Chad L. Tue .
"Recombinant yeast having enhanced gamma valerolactone tolerance and methods of use". United States. https://www.osti.gov/servlets/purl/1460543.
@article{osti_1460543,
title = {Recombinant yeast having enhanced gamma valerolactone tolerance and methods of use},
author = {Piotrowski, Jeff S. and Sato, Trey K. and Myers, Chad L.},
abstractNote = {The present invention relates to materials and methods for the production of ethanol. More particularly, the present invention provides genetically modified strains of Saccharomyces cerevisiae having enhanced tolerance for gamma valerolactone (GVL) toxicity. Also provided are methods of using such genetically engineered yeast strains for improved GVL-mediated hydrolysis of lignocellulosic biomass for industrial-scale ethanol production.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jun 26 00:00:00 EDT 2018},
month = {Tue Jun 26 00:00:00 EDT 2018}
}
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Works referenced in this record:
Mutant Saccharomyces Cerevisiae Strain Utilizing Xylose For Ethanol Production
patent-application, June 2007
- Karhumaa, Kaisa; Gorwa-Grauslund, Marie-Francoise
- US Patent Application 11/557363; 20070141690
Mutations in Iron-Sulfur Cluster Proteins that Improve Xylose Utilization
patent-application, February 2016
- Froehlich, Allan; Henningsen, Brooks; Covalla, Sean
- US Patent Application 14/821955; 20160040153
PAD1 and FDC1 are essential for the decarboxylation of phenylacrylic acids in Saccharomyces cerevisiae
journal, June 2010
- Mukai, Nobuhiko; Masaki, Kazuo; Fujii, Tsutomu
- Journal of Bioscience and Bioengineering, Vol. 109, Issue 6, p. 564-569