Process and targets for production of no-carrier-added radiotin
Abstract
One embodiment of the present invention includes a process for production and recovery of no-carrier-added radioactive tin (NCA radiotin). An antimony target can be irradiated with a beam of accelerated particles forming NCA radiotin, followed by separation of the NCA radiotin from the irradiated target. The target is metallic Sb in a hermetically sealed shell. The shell can be graphite, molybdenum, or stainless steel. The irradiated target can be removed from the shell by chemical or mechanical means, and dissolved in an acidic solution. Sb can be removed from the dissolved irradiated target by extraction. NCA radiotin can be separated from the remaining Sb and other impurities using chromatography on silica gel sorbent. NCA tin-117m can be obtained from this process. NCA tin-117m can be used for labeling organic compounds and biological objects to be applied in medicine for imaging and therapy of various diseases.
- Inventors:
- Issue Date:
- Research Org.:
- Brookhaven National Laboratory (BNL), Upton, NY (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1129379
- Patent Number(s):
- 8705681
- Application Number:
- 11/962,851
- Assignee:
- Brookhaven Science Associates, LLC (Upton, NY)
- Patent Classifications (CPCs):
-
G - PHYSICS G21 - NUCLEAR PHYSICS G21G - CONVERSION OF CHEMICAL ELEMENTS
H - ELECTRICITY H05 - ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR H05H - PLASMA TECHNIQUE
- DOE Contract Number:
- AC02-98CH10886
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2007 Dec 21
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 73 NUCLEAR PHYSICS AND RADIATION PHYSICS
Citation Formats
Srivastava, Suresh C, Zhuikov, Boris Leonidovich, Ermolaev, Stanislav Victorovich, Konyakhin, Nikolay Alexandrovich, Kokhanyuk, Vladimir Mikhailovich, Khamyanov, Stepan Vladimirovich, and Togaeva, Natalya Roaldovna. Process and targets for production of no-carrier-added radiotin. United States: N. p., 2014.
Web.
Srivastava, Suresh C, Zhuikov, Boris Leonidovich, Ermolaev, Stanislav Victorovich, Konyakhin, Nikolay Alexandrovich, Kokhanyuk, Vladimir Mikhailovich, Khamyanov, Stepan Vladimirovich, & Togaeva, Natalya Roaldovna. Process and targets for production of no-carrier-added radiotin. United States.
Srivastava, Suresh C, Zhuikov, Boris Leonidovich, Ermolaev, Stanislav Victorovich, Konyakhin, Nikolay Alexandrovich, Kokhanyuk, Vladimir Mikhailovich, Khamyanov, Stepan Vladimirovich, and Togaeva, Natalya Roaldovna. Tue .
"Process and targets for production of no-carrier-added radiotin". United States. https://www.osti.gov/servlets/purl/1129379.
@article{osti_1129379,
title = {Process and targets for production of no-carrier-added radiotin},
author = {Srivastava, Suresh C and Zhuikov, Boris Leonidovich and Ermolaev, Stanislav Victorovich and Konyakhin, Nikolay Alexandrovich and Kokhanyuk, Vladimir Mikhailovich and Khamyanov, Stepan Vladimirovich and Togaeva, Natalya Roaldovna},
abstractNote = {One embodiment of the present invention includes a process for production and recovery of no-carrier-added radioactive tin (NCA radiotin). An antimony target can be irradiated with a beam of accelerated particles forming NCA radiotin, followed by separation of the NCA radiotin from the irradiated target. The target is metallic Sb in a hermetically sealed shell. The shell can be graphite, molybdenum, or stainless steel. The irradiated target can be removed from the shell by chemical or mechanical means, and dissolved in an acidic solution. Sb can be removed from the dissolved irradiated target by extraction. NCA radiotin can be separated from the remaining Sb and other impurities using chromatography on silica gel sorbent. NCA tin-117m can be obtained from this process. NCA tin-117m can be used for labeling organic compounds and biological objects to be applied in medicine for imaging and therapy of various diseases.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 22 00:00:00 EDT 2014},
month = {Tue Apr 22 00:00:00 EDT 2014}
}
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