Xylose utilization in recombinant zymomonas

Caimi, Perry G; McCole, Laura; Tao, Luan; Tomb, Jean-Francois; Viitanen, Paul V

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Title: Xylose utilization in recombinant zymomonas

Abstract

Xylose-utilizing Zymomonas strains studied were found to accumulate ribulose when grown in xylose-containing media. Engineering these strains to increase ribose-5-phosphate isomerase activity led to reduced ribulose accumulation, improved growth, improved xylose utilization, and increased ethanol production.

Inventors:: Caimi, Perry G; McCole, Laura; Tao, Luan; Tomb, Jean-Francois; Viitanen, Paul V

Issue Date:: Tue Mar 25 00:00:00 EDT 2014

Research Org.:: E I du Pont de Nemours and Company, Wilmington, DE, USA

Sponsoring Org.:: USDOE

OSTI Identifier:: 1128545

Patent Number(s):: 8679822

Application Number:: 13/161,734

Assignee:: E I du Pont de Nemours and Company (Wilmington, DE)

Patent Classifications (CPCs):: C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

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C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C12N1/20 - Bacteria {
C12N9/90 - Isomerases
C12N9/92 - Glucose isomerase {

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C12P7/065 - {with microorganisms other than yeasts}
C12P7/10 - substrate containing cellulosic material

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02E - REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
Y02E50/10 - Biofuels

Show less

DOE Contract Number:: FC36-07GO17056

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 59 BASIC BIOLOGICAL SCIENCES

Citation Formats


                    Caimi, Perry G, McCole, Laura, Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Xylose utilization in recombinant zymomonas.  United States: N. p., 2014. 
        Web.

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                    Caimi, Perry G, McCole, Laura, Tao, Luan, Tomb, Jean-Francois, & Viitanen, Paul V. Xylose utilization in recombinant zymomonas.  United States.

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                    Caimi, Perry G, McCole, Laura, Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Tue .  
        "Xylose utilization in recombinant zymomonas".  United States.  https://www.osti.gov/servlets/purl/1128545.

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@article{osti_1128545,

  title        = {Xylose utilization in recombinant zymomonas},

  author       = {Caimi, Perry G and McCole, Laura and Tao, Luan and Tomb, Jean-Francois and Viitanen, Paul V},

  abstractNote = {Xylose-utilizing Zymomonas strains studied were found to accumulate ribulose when grown in xylose-containing media. Engineering these strains to increase ribose-5-phosphate isomerase activity led to reduced ribulose accumulation, improved growth, improved xylose utilization, and increased ethanol production.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue Mar 25 00:00:00 EDT 2014},

  month        = {Tue Mar 25 00:00:00 EDT 2014}

}

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Works referenced in this record:

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