Anti-influenza M2e antibody
Abstract
Humanized recombinant and monoclonal antibodies specific for the ectodomain of the influenza virus M2 ion channel protein are disclosed. The antibodies of the invention have anti-viral activity and may be useful as anti-viral therapeutics and/or prophylactic/vaccine agents for inhibiting influenza virus replication and for treating individuals infected with influenza.
- Inventors:
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1083632
- Patent Number(s):
- 8420794
- Application Number:
- 13/296,414
- Assignee:
- Los Alamos National Security, LLC (Los Alamos, NM)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
- DOE Contract Number:
- AC52-06 NA 25396
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Bradbury, Andrew M. Anti-influenza M2e antibody. United States: N. p., 2013.
Web.
Bradbury, Andrew M. Anti-influenza M2e antibody. United States.
Bradbury, Andrew M. Tue .
"Anti-influenza M2e antibody". United States. https://www.osti.gov/servlets/purl/1083632.
@article{osti_1083632,
title = {Anti-influenza M2e antibody},
author = {Bradbury, Andrew M.},
abstractNote = {Humanized recombinant and monoclonal antibodies specific for the ectodomain of the influenza virus M2 ion channel protein are disclosed. The antibodies of the invention have anti-viral activity and may be useful as anti-viral therapeutics and/or prophylactic/vaccine agents for inhibiting influenza virus replication and for treating individuals infected with influenza.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 16 00:00:00 EDT 2013},
month = {Tue Apr 16 00:00:00 EDT 2013}
}
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Construction of miniantibodies for the in vivo study of human autoimmune diseases in animal models
journal, January 2007
- Di Niro, Roberto; Ziller, Federica; Florian, Fiorella
- BMC Biotechnology, Vol. 7, Issue 1
Fine specificity and sequence of antibodies directed against the ectodomain of matrix protein 2 of influenza A virus☆
journal, July 2006
- Zhang, M.; Zharikova, D.; Mozdzanowska, K.
- Molecular Immunology, Vol. 43, Issue 14
Effects of humanization by variable domain resurfacing on the antiviral activity of a single-chain antibody against respiratory syncytial virus
journal, April 1999
- Delagrave, Simon; Catalan, John; Sweet, Charles
- Protein Engineering, Design and Selection, Vol. 12, Issue 4