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Title: Three-dimensional molecular imaging by infrared laser ablation electrospray ionization mass spectrometry

Abstract

The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation with electrospray ionization (ESI).

Inventors:
;
Issue Date:
Research Org.:
George Washington Univ., Washington, DC (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1079220
Patent Number(s):
8299429
Application Number:
13/101,518
Assignee:
The George Washington University (Washington, DC)
Patent Classifications (CPCs):
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
DOE Contract Number:  
FG02-01ER15129
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Vertes, Akos, and Nemes, Peter. Three-dimensional molecular imaging by infrared laser ablation electrospray ionization mass spectrometry. United States: N. p., 2012. Web.
Vertes, Akos, & Nemes, Peter. Three-dimensional molecular imaging by infrared laser ablation electrospray ionization mass spectrometry. United States.
Vertes, Akos, and Nemes, Peter. Tue . "Three-dimensional molecular imaging by infrared laser ablation electrospray ionization mass spectrometry". United States. https://www.osti.gov/servlets/purl/1079220.
@article{osti_1079220,
title = {Three-dimensional molecular imaging by infrared laser ablation electrospray ionization mass spectrometry},
author = {Vertes, Akos and Nemes, Peter},
abstractNote = {The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation with electrospray ionization (ESI).},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Oct 30 00:00:00 EDT 2012},
month = {Tue Oct 30 00:00:00 EDT 2012}
}

Works referenced in this record:

In Situ Metabolic Profiling of Single Cells by Laser Ablation Electrospray Ionization Mass Spectrometry
journal, October 2009


Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions
journal, April 2005


Matrix-assisted laser desorption and ionization in the OH and CO absorption bands of aliphatic and aromatic matrices: dependence on laser wavelength and temporal beam profile
journal, December 1997


Direct Protein Detection from Biological Media through Electrospray-Assisted Laser Desorption Ionization/Mass Spectrometry
journal, May 2006


Intact and top-down characterization of biomolecules and direct analysis using infrared matrix-assisted laser desorption electrospray ionization coupled to FT-ICR mass spectrometry
journal, April 2009


FT-IR imaging of native and tissue-engineered bone and cartilage
journal, May 2007


New dimension in nano-imaging: breaking through the diffraction limit with scanning near-field optical microscopy
journal, November 2004


Nanoscale Atmospheric Pressure Laser Ablation-Mass Spectrometry
journal, April 2001


Laser Ablation Electrospray Ionization for Atmospheric Pressure, in Vivo, and Imaging Mass Spectrometry
journal, November 2007


Free-electron-laser-based biophysical and biomedical instrumentation
journal, July 2003


Infrared laser-assisted desorption electrospray ionization mass spectrometry
journal, January 2008