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Title: Methods for magnetic resonance analysis using magic angle technique

Abstract

Methods of performing a magnetic resonance analysis of a biological object are disclosed that include placing the object in a main magnetic field (that has a static field direction) and in a radio frequency field; rotating the object at a frequency of less than about 100 Hz around an axis positioned at an angle of about 54.degree.44' relative to the main magnetic static field direction; pulsing the radio frequency to provide a sequence that includes a phase-corrected magic angle turning pulse segment; and collecting data generated by the pulsed radio frequency. In particular embodiments the method includes pulsing the radio frequency to provide at least two of a spatially selective read pulse, a spatially selective phase pulse, and a spatially selective storage pulse. Further disclosed methods provide pulse sequences that provide extended imaging capabilities, such as chemical shift imaging or multiple-voxel data acquisition.

Inventors:
 [1];  [2];  [2];  [2]
  1. Richland, WA
  2. Kennewick, WA
Issue Date:
Research Org.:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1032714
Patent Number(s):
8064982
Application Number:
11/562,390
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01R - MEASURING ELECTRIC VARIABLES
DOE Contract Number:  
AC06-76RL01830
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Hu, Jian Zhi, Wind, Robert A, Minard, Kevin R, and Majors, Paul D. Methods for magnetic resonance analysis using magic angle technique. United States: N. p., 2011. Web.
Hu, Jian Zhi, Wind, Robert A, Minard, Kevin R, & Majors, Paul D. Methods for magnetic resonance analysis using magic angle technique. United States.
Hu, Jian Zhi, Wind, Robert A, Minard, Kevin R, and Majors, Paul D. Tue . "Methods for magnetic resonance analysis using magic angle technique". United States. https://www.osti.gov/servlets/purl/1032714.
@article{osti_1032714,
title = {Methods for magnetic resonance analysis using magic angle technique},
author = {Hu, Jian Zhi and Wind, Robert A and Minard, Kevin R and Majors, Paul D},
abstractNote = {Methods of performing a magnetic resonance analysis of a biological object are disclosed that include placing the object in a main magnetic field (that has a static field direction) and in a radio frequency field; rotating the object at a frequency of less than about 100 Hz around an axis positioned at an angle of about 54.degree.44' relative to the main magnetic static field direction; pulsing the radio frequency to provide a sequence that includes a phase-corrected magic angle turning pulse segment; and collecting data generated by the pulsed radio frequency. In particular embodiments the method includes pulsing the radio frequency to provide at least two of a spatially selective read pulse, a spatially selective phase pulse, and a spatially selective storage pulse. Further disclosed methods provide pulse sequences that provide extended imaging capabilities, such as chemical shift imaging or multiple-voxel data acquisition.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Nov 22 00:00:00 EST 2011},
month = {Tue Nov 22 00:00:00 EST 2011}
}

Works referenced in this record:

Echo-planar imaging.
journal, September 1994


Localized in vivo isotropic-anisotropic correlation1H NMR spectroscopy using ultraslow magic angle spinning
journal, January 2005