Portable sample preparation and analysis system for micron and sub-micron particle characterization using light scattering and absorption spectroscopy
Abstract
There is provided a method and device for remote sampling, preparation and optical interrogation of a sample using light scattering and light absorption methods. The portable device is a filtration-based device that removes interfering background particle material from the sample matrix by segregating or filtering the chosen analyte from the sample solution or matrix while allowing the interfering background particles to be pumped out of the device. The segregated analyte is then suspended in a diluent for analysis. The device is capable of calculating an initial concentration of the analyte, as well as diluting the analyte such that reliable optical measurements can be made. Suitable analytes include cells, microorganisms, bioparticles, pathogens and diseases. Sample matrixes include biological fluids such as blood and urine, as well as environmental samples including waste water.
- Inventors:
-
- Los Alamos, NM
- Barranquilla, CO
- Fort Walton Beach, FL
- Santa Fe, NM
- Temple Terrace, FL
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1019396
- Patent Number(s):
- 7986399
- Application Number:
- US Patent Application 11/877,136
- Assignee:
- Los Alamos National Security, LLC (Los Alamos, NM)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC52-06NA25396
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Stark, Peter C, Zurek, Eduardo, Wheat, Jeffrey V, Dunbar, John M, Olivares, Jose A, Garcia-Rubio, Luis H, and Ward, Michael D. Portable sample preparation and analysis system for micron and sub-micron particle characterization using light scattering and absorption spectroscopy. United States: N. p., 2011.
Web.
Stark, Peter C, Zurek, Eduardo, Wheat, Jeffrey V, Dunbar, John M, Olivares, Jose A, Garcia-Rubio, Luis H, & Ward, Michael D. Portable sample preparation and analysis system for micron and sub-micron particle characterization using light scattering and absorption spectroscopy. United States.
Stark, Peter C, Zurek, Eduardo, Wheat, Jeffrey V, Dunbar, John M, Olivares, Jose A, Garcia-Rubio, Luis H, and Ward, Michael D. Tue .
"Portable sample preparation and analysis system for micron and sub-micron particle characterization using light scattering and absorption spectroscopy". United States. https://www.osti.gov/servlets/purl/1019396.
@article{osti_1019396,
title = {Portable sample preparation and analysis system for micron and sub-micron particle characterization using light scattering and absorption spectroscopy},
author = {Stark, Peter C and Zurek, Eduardo and Wheat, Jeffrey V and Dunbar, John M and Olivares, Jose A and Garcia-Rubio, Luis H and Ward, Michael D},
abstractNote = {There is provided a method and device for remote sampling, preparation and optical interrogation of a sample using light scattering and light absorption methods. The portable device is a filtration-based device that removes interfering background particle material from the sample matrix by segregating or filtering the chosen analyte from the sample solution or matrix while allowing the interfering background particles to be pumped out of the device. The segregated analyte is then suspended in a diluent for analysis. The device is capable of calculating an initial concentration of the analyte, as well as diluting the analyte such that reliable optical measurements can be made. Suitable analytes include cells, microorganisms, bioparticles, pathogens and diseases. Sample matrixes include biological fluids such as blood and urine, as well as environmental samples including waste water.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jul 26 00:00:00 EDT 2011},
month = {Tue Jul 26 00:00:00 EDT 2011}
}