Nucleic acids encoding antifungal polypeptides and uses thereof
Abstract
Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include an amino acid sequence, and variants and fragments thereof, for an antipathogenic polypeptide that was isolated from a fungal fermentation broth. Nucleic acid molecules that encode the antipathogenic polypeptides of the invention, and antipathogenic domains thereof, are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the invention are also disclosed.
- Inventors:
-
- Granger, IA
- Kyiv, UA
- Norwalk, IA
- Elliott City, MD
- Avondale, PA
- Port Deposit, MD
- Des Moines, IA
- Richmond, CA
- Johnston, IA
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1014929
- Patent Number(s):
- 7825294
- Application Number:
- US Patent Application 12/503,952
- Assignee:
- Pioneer Hi-Bred International, Inc. (Johnston, IA); E.I. du Pont de Nemours and Company (Wilmington, DE); The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A01 - AGRICULTURE A01N - PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
- DOE Contract Number:
- AC02-05CH11231
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Altier, Daniel J, Ellanskaya, I A, Gilliam, Jacob T, Hunter-Cevera, Jennie, Presnail, James K, Schepers, Eric, Simmons, Carl R, Torok, Tamas, and Yalpani, Nasser. Nucleic acids encoding antifungal polypeptides and uses thereof. United States: N. p., 2010.
Web.
Altier, Daniel J, Ellanskaya, I A, Gilliam, Jacob T, Hunter-Cevera, Jennie, Presnail, James K, Schepers, Eric, Simmons, Carl R, Torok, Tamas, & Yalpani, Nasser. Nucleic acids encoding antifungal polypeptides and uses thereof. United States.
Altier, Daniel J, Ellanskaya, I A, Gilliam, Jacob T, Hunter-Cevera, Jennie, Presnail, James K, Schepers, Eric, Simmons, Carl R, Torok, Tamas, and Yalpani, Nasser. Tue .
"Nucleic acids encoding antifungal polypeptides and uses thereof". United States. https://www.osti.gov/servlets/purl/1014929.
@article{osti_1014929,
title = {Nucleic acids encoding antifungal polypeptides and uses thereof},
author = {Altier, Daniel J and Ellanskaya, I A and Gilliam, Jacob T and Hunter-Cevera, Jennie and Presnail, James K and Schepers, Eric and Simmons, Carl R and Torok, Tamas and Yalpani, Nasser},
abstractNote = {Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include an amino acid sequence, and variants and fragments thereof, for an antipathogenic polypeptide that was isolated from a fungal fermentation broth. Nucleic acid molecules that encode the antipathogenic polypeptides of the invention, and antipathogenic domains thereof, are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the invention are also disclosed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Nov 02 00:00:00 EDT 2010},
month = {Tue Nov 02 00:00:00 EDT 2010}
}
Works referenced in this record:
Unexpected homology between inducible cell wall protein QID74 of filamentous fungi and BR3 salivary protein of the insect Chironomus
journal, May 1998
- Rey, M.; Ohno, S.; Pintor-Toro, J. A.
- Proceedings of the National Academy of Sciences, Vol. 95, Issue 11