13362 K
103 pp.
 
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TitleUnderstanding our Genetic Inheritance: The U.S. Human Genome Project, The First Five Years FY 1991--1995
Publication DateApril 1990
Report NumberDOE/ER-0452P
Unique IdentifierACC0487
Other NumbersLegacy ID: DE90008240; OSTI ID: 6958032
Research OrgNational Center for Human Genome Research, Bethesda, MD (USA); Office of Health and Environmental Research, U.S. Department of Energy (DOE) Office of Energy Research, Washington, DC (USA)
Sponsoring OrgU.S. Department of Energy (DOE) Office of Energy Research (DOE/ER)
Other InformationHuman Genome Initiative: goals and implementation
Subject59 Basic Biological Sciences; Chromosomes; Genetic Mapping; Genetics; Research Programs; Man; DNA Sequencing; Biotechnology; Data Analysis; Genes; Genetic Engineering; Hereditary Diseases; Planning; Program Management; Radiation Effects; Animals; Biology; Diseases; Mammals; Management; Mapping; Primates; Structural Chemical Analysis; Vertebrates; 550200* -- Biochemistry; 550400 -- Genetics;
Related Web PagesHuman Genome: DOE Origins
AbstractThe Human Genome Initiative is a worldwide research effort with the goal of analyzing the structure of human DNA and determining the location of the estimated 100,000 human genes. In parallel with this effort, the DNA of a set of model organisms will be studied to provide the comparative information necessary for understanding the functioning of the human genome. The information generated by the human genome project is expected to be the source book for biomedical science in the 21st century and will by of immense benefit to the field of medicine. It will help us to understand and eventually treat many of the more than 4000 genetic diseases that affect mankind, as well as the many multifactorial diseases in which genetic predisposition plays an important role. A centrally coordinated project focused on specific objectives is believed to be the most efficient and least expensive way of obtaining this information. The basic data produced will be collected in electronic databases that will make the information readily accessible on convenient form to all who need it. This report describes the plans for the U.S. human genome project and updates those originally prepared by the Office of Technology Assessment (OTA) and the National Research Council (NRC) in 1988. In the intervening two years, improvements in technology for almost every aspect of genomics research have taken place. As a result, more specific goals can now be set for the project.
13362 K
103 pp.
 
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