2572 K
17 pp.
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TitleThe Heritage of Radiotracers for PET
Author(s)Fowler, J. S.; Wolf, A. P.
Publication DateMay 1988
Report NumberBNL-41807
Unique IdentifierACC0243
Other NumbersCONF-8805211-2; Legacy ID: DE89001608; OSTI ID: 6706433
Research OrgBrookhaven National Laboratory (BNL), Upton, NY (USA)
Contract NoAC02-76CH00016
Sponsoring OrgUS Department of Energy (USDOE)
Other Information12th Sigrid Juselius Foundation Symposium on Tracers in Diagnostic Imaging; 22 May 1988; Helsinki, Finland
Subject440300 -- Miscellaneous Instruments -- (-1989); Image Processing -- Technology Assessment; Positron Computed Tomography -- Evaluation; Diagnostic Uses; Historical Aspects; Labelled Compounds; Neurology; Tracer Techniques
KeywordsComputerized Tomography; Diagnostic Techniques; Emission Computed Tomography; Isotope Applications; Medicine; Processing; Tomography; Uses
Related Web PagesPositron Emission Tomography [PET] and Positron Scanner
AbstractThe history of PET research clearly demonstrates that it is advances in chemistry coupled with a detailed examination of the biochemistry of new radiotracers which has allowed the PET method to be applied to new areas of biology and medicine. Radiotracers whose regional distribution reflects glucose metabolism, neutrotransmitter activity and enzyme activity have all required the development of rapid synthetic methods for the radiotracers themselves and the characterization of their biochemical behavior. This article traces some of the advances in the production of labeled precursors and in radiotracer synthesis and evaluation which have shaped the rapidly expanding application of PET to problems in the neurosciences, in cardiology and in oncology.
2572 K
17 pp.
View Document 

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