| 2572 K 17 pp. |   | |
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| Title | The Heritage of Radiotracers for PET | |
| Author(s) | Fowler, J. S.; Wolf, A. P. | |
| Publication Date | May 1988 | |
| Report Number | BNL-41807 | |
| Unique Identifier | ACC0243 | |
| Other Numbers | CONF-8805211-2; Legacy ID: DE89001608; OSTI ID: 6706433 | |
| Research Org | Brookhaven National Laboratory (BNL), Upton, NY (USA) | |
| Contract No | AC02-76CH00016 | |
| Sponsoring Org | US Department of Energy (USDOE) | |
| Other Information | 12th Sigrid Juselius Foundation Symposium on Tracers in Diagnostic Imaging; 22 May 1988; Helsinki, Finland | |
| Subject | 440300 -- Miscellaneous Instruments -- (-1989); Image Processing -- Technology Assessment; Positron Computed Tomography -- Evaluation; Diagnostic Uses; Historical Aspects; Labelled Compounds; Neurology; Tracer Techniques | |
| Keywords | Computerized Tomography; Diagnostic Techniques; Emission Computed Tomography; Isotope Applications; Medicine; Processing; Tomography; Uses | |
| Related Web Pages | Positron Emission Tomography [PET] and Positron Scanner | |
| Abstract | The history of PET research clearly demonstrates that it is advances in chemistry coupled with a detailed examination of the biochemistry of new radiotracers which has allowed the PET method to be applied to new areas of biology and medicine. Radiotracers whose regional distribution reflects glucose metabolism, neutrotransmitter activity and enzyme activity have all required the development of rapid synthetic methods for the radiotracers themselves and the characterization of their biochemical behavior. This article traces some of the advances in the production of labeled precursors and in radiotracer synthesis and evaluation which have shaped the rapidly expanding application of PET to problems in the neurosciences, in cardiology and in oncology. | |
| 2572 K 17 pp. |   | |
| View Document |   | |
|   | ||