534 K
7 pp.
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TitleSome Recent Developments in Treatment Planning Software and Methodology for BNCT
Author(s)Nigg, D. W.; Wheeler, F. J.; Wessol, D. E.; et al.
Publication Date1996
Report NumberBNL--64624
Unique IdentifierACC0227
Other NumbersCONF-9609293--; Legacy ID: DE97008898; OSTI ID: 539846
Research OrgBrookhaven National Laboratory, Upton, NY (United States); Idaho National Engineering Laboratory, Idaho Falls, ID (United States)
Contract NoAC02-76CH00016; AC07-94ID13223
Sponsoring OrgUSDOE Office of Energy Research, Washington, DC (United States)
Other Information7. International Symposium on Neutron Capture Therapy for Cancer, Zurich (Switzerland), 4-7 Sep 1996
Subject55 Biology and Medicine, Basic Studies; 99 Mathematics, Computers, Information Science, Management, Law, Miscellaneous; Gliomas; Neutron Capture Therapy; Computerized Simulation; Boron; B Codes; Dosimetry
Related Web PagesDOE Research Contributions to Radiation and Cancer Therapy
AbstractOver the past several years the Idaho National Engineering Laboratory (INEL) has led the development of a unique, internationally-recognized set of software modules (BNCT-rtpe) for computational dosimetry and treatment planning for Boron Neutron Capture Therapy (BNCT). The computational capability represented by this software is essential to the proper administration of all forms of radiotherapy for cancer. Such software addresses the need to perform pretreatment computation and optimization of the radiation dose distribution in the target volume. This permits the achievement of the optimal therapeutic ratio (tumor dose relative to critical normal tissue dose) for each individual patient via a systematic procedure for specifying the appropriate irradiation parameters to be employed for a given treatment. These parameters include angle of therapy beam incidence, beam aperture and shape, and beam intensity as a function of position across the beam front. The INEL software is used for treatment planning in the current series of human glioma trials at Brookhaven National Laboratory (BNL) and has also been licensed for research and developmental purposes to several other BNCT research centers in the US and in Europe.
534 K
7 pp.
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