Relevance of in vivo models in melanoma skin cancer
Conference
·
OSTI ID:188504
A discussion of possible wavelength dependence of induction of cutaneous malignant melanoma (CMM) is provided. Strengths and weaknesses of various experimental approaches to better understanding of the prevalence of CMM in different human populations including latitude effects are compared. Further the advantages and limitations of the use of the laboratory opossum (Monodelphis domestic), transgenic mice containing SV40 ongogene sequences under tyrosinase promoter control, and a backcross hybrid fish of the genus Xenophorus are contrasted.
- Research Organization:
- Brookhaven National Lab. (BNL), Upton, NY (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- AC02-76CH00016
- OSTI ID:
- 188504
- Report Number(s):
- BNL-62460; CONF-9510289-1; ON: DE96004163
- Resource Relation:
- Conference: International symposium on photocarcinogenesis: mechanisms, models and human health implications, Washington, DC (United States), 27-28 Oct 1995; Other Information: PBD: [1995]
- Country of Publication:
- United States
- Language:
- English
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· Proceedings of the National Academy of Sciences of the United States of America; (USA)
·
OSTI ID:188504