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Title: Method of coating a substrate with a calcium phosphate compound

Patent ·
OSTI ID:873212

The present invention is a method of coating a substrate with a calcium phosphate compound using plasma enhanced MOCVD. The substrate is a solid material that may be porous or non-porous, including but not limited to metal, ceramic, glass and combinations thereof. The coated substrate is preferably used as an implant, including but not limited to orthopaedic, dental and combinations thereof. Calcium phosphate compound includes but is not limited to tricalcium phosphate (TCP), hydroxyapatite (HA) and combinations thereof. TCP is preferred on a titanium implant when implant resorbability is desired. HA is preferred when the bone bonding of new bone tissue into the structure of the implant is desired. Either or both of TCP and/or HA coated implants may be placed into a solution with an agent selected from the group of protein, antibiotic, antimicrobial, growth factor and combinations thereof that can be adsorbed into the coating before implantation. Once implanted, the release of TCP will also release the agent to improve growth of new bone tissues and/or to prevent infection.

Research Organization:
Battelle Memorial Institute, Columbus, OH (United States)
DOE Contract Number:
AC06-76RL01830
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Number(s):
US 6113993
OSTI ID:
873212
Country of Publication:
United States
Language:
English

References (3)

Surface and bulk study of calcium phosphate bioceramics obtained by Metal Organic Chemical Vapor Deposition journal August 1996
Highly adhesive hydroxyapatite coatings on titanium alloy formed by ion beam assisted deposition journal July 1997
Ceramic Thin-Film Formation on Functionalized Interfaces Through Biomimetic Processing journal April 1994