Role of preoperative bone scan in carcinoma of the breast

Journal Article · Sat May 01 00:00:00 EDT 1976 · Surg. Gynecol. Obstet.; (United States)

OSTI ID:7312686

El-Domeiri, A A; Shroff, S

The spread of carcinoma of the breast beyond the mammary tissue and regional lymph nodes most commonly occurs in the axial skeleton. The results of several investigations have shown that scintiscans are more accurate and sensitive than radiographs for the early detection of metastases to the bone. In recent years, bone seeking radionuclides, such as /sup 87/Sr, /sup 87//sup mr/Sr and /sup 18/F, have been used for skeletal imaging. Currently, /sup 99//sup m/Tc polyphosphate is the agent most widely used, since it is readily available, easy to produce and, because it has a high yield of monoenergetic gamma emissions, can be used with either a gamma camera or a rectilinear scanner. Because of the safety and the relative ease with which a bone scan can be obtained, many investigators have advocated its routine use prior to radical mastectomy. In recent years, a number of investigators have reported a relatively high incidence of abnormal postoperative bone scans in patients who had carcinoma of the breast. This prospective study was undertaken to evaluate the yield of positive scan results in a group of unselected patients with carcinoma of the breast, according to the size of the primary tumor.

• Research Organization: Univ. of Illinois, Chicago
• OSTI ID: 7312686
• Journal Information: Surg. Gynecol. Obstet.; (United States), Vol. 142:5
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
METASTASES
DIAGNOSIS
SKELETON
SCINTISCANNING
TECHNETIUM 99
CARCINOMAS
ISOMERIC NUCLEI
MAMMARY GLANDS
PATIENTS
PHOSPHATES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
PHOSPHORUS COMPOUNDS
RADIOISOTOPE SCANNING
RADIOISOTOPES
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics