Bifunctional chelates of Rh-105 and Au-199 as potential radiotherapeutic agents
Since last year we have: continued the synthesis of pentadentate bifunctional chelating agents based on diethylene triamine; studied the chelation Rh-105, Au-198 (as model for Au-199) and Tc-99m with these agents as well as chelation of Pd-109, Cu-67, In-111, and Co-57 with some of them; synthesized a new class of potential bifunctional chelating agents based on phenylene diamine; investigated the behavior of Au-198 as a model for Au-199; begun synthesis of bifunctional chelating agents based on terpyridly and similar ligands; and continued attempts to produce tetradentate bifunctional chelates based on diaminopropane. Each of these will be addressed in this report.
- Research Organization:
- Missouri Univ., Columbia, MO (USA). Dept. of Chemistry
- Sponsoring Organization:
- DOE/ER
- DOE Contract Number:
- FG02-86ER60400
- OSTI ID:
- 7170301
- Report Number(s):
- DOE/ER/60400-4; ON: DE90009963; TRN: 90-015142
- Country of Publication:
- United States
- Language:
- English
Similar Records
Bifunctional chelates of Rh-105 and Au-199 as potential radiotherapeutic agents
[Bifunctional chelates of Rh-105, Au-199, and other metallic radionuclides as potential radiotherapeutic agents]
(Bifunctional chelates of Rh-105, Au-199, and other metallic radionuclides as potential radiotherapeutic agents)
Technical Report
·
Fri Jan 25 00:00:00 EST 1991
·
OSTI ID:7170301
[Bifunctional chelates of Rh-105, Au-199, and other metallic radionuclides as potential radiotherapeutic agents]
Technical Report
·
Tue Dec 31 00:00:00 EST 1991
·
OSTI ID:7170301
(Bifunctional chelates of Rh-105, Au-199, and other metallic radionuclides as potential radiotherapeutic agents)
Technical Report
·
Tue Jan 01 00:00:00 EST 1991
·
OSTI ID:7170301
Related Subjects
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
62 RADIOLOGY AND NUCLEAR MEDICINE
CHELATING AGENTS
CHEMICAL PREPARATION
GOLD COMPLEXES
RHODIUM COMPLEXES
CHELATES
COBALT COMPLEXES
COMPLEXES
COPPER COMPLEXES
INDIUM COMPLEXES
LIGANDS
MOLECULAR STRUCTURE
PALLADIUM COMPLEXES
PROGRESS REPORT
RADIOISOTOPES
RADIOTHERAPY
TECHNETIUM COMPLEXES
DOCUMENT TYPES
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
RADIOLOGY
SYNTHESIS
THERAPY
TRANSITION ELEMENT COMPLEXES
400703* - Radiochemistry & Nuclear Chemistry- Radioisotope Production
550604 - Medicine- Unsealed Radionuclides in Therapy- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
CHELATING AGENTS
CHEMICAL PREPARATION
GOLD COMPLEXES
RHODIUM COMPLEXES
CHELATES
COBALT COMPLEXES
COMPLEXES
COPPER COMPLEXES
INDIUM COMPLEXES
LIGANDS
MOLECULAR STRUCTURE
PALLADIUM COMPLEXES
PROGRESS REPORT
RADIOISOTOPES
RADIOTHERAPY
TECHNETIUM COMPLEXES
DOCUMENT TYPES
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
RADIOLOGY
SYNTHESIS
THERAPY
TRANSITION ELEMENT COMPLEXES
400703* - Radiochemistry & Nuclear Chemistry- Radioisotope Production
550604 - Medicine- Unsealed Radionuclides in Therapy- (1980-)