Matrix modification for furnace atomic absorption spectrometric determination of arsenic in whole human blood

Journal Article · · J. Anal. Toxicol.; (United States)

DOI:https://doi.org/10.1093/jat/9.5.213· OSTI ID:7163730

Eaton, D K; McCutcheon, J R

A method for the determination of arsenic in whole human blood is presented. To decrease the matrix effects from this complex sample, the blood was prediluted with a matrix modifier solution. The modifier solution contained a surfactant, Triton X-100, which homogenized the sample and allowed accurate pipetting by an autosampler. The modifier also contained nickel nitrate which stabilized the arsenic and allowed ash temperatures of 1400/sup 0/C without loss of the arsenic. The method exhibited a sensitivity of 5 ..mu..g/L (concentration/1% absorption) which was sufficient for the forensic evaluation of elevated arsenic levels in the blood.

• Research Organization: Texas Dept. of Public Safety, Austin
• OSTI ID: 7163730
• Journal Information: J. Anal. Toxicol.; (United States), Vol. 9:5
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ARSENIC COMPOUNDS
BLOOD CHEMISTRY
BLOOD
SAMPLE PREPARATION
ABSORPTION SPECTROSCOPY
MAN
NICKEL NITRATES
SURFACTANTS
ANIMALS
BIOLOGICAL MATERIALS
BODY FLUIDS
MAMMALS
MATERIALS
NICKEL COMPOUNDS
NITRATES
NITROGEN COMPOUNDS
OXYGEN COMPOUNDS
PRIMATES
SPECTROSCOPY
TRANSITION ELEMENT COMPOUNDS
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology