Place of brachytherapy in the treatment of carcinoma of the tonsil with lingual extension
One hundred forty-four of 170 patients (85%) were seen with cancer of the tonsil and received radical irradiation between 1959 and 1980. A 39% crude 3-year disease-free survival rate and a 51% locoregional control rate were observed. Locoregional relapse related to T Stage was 6, 43, 58, and 64% for T1, T2, T3, and T4, respectively. Fifty-four of 144 patients (37%) showed tongue extension, 20% in T1-T2 stages and 50% in T3-T4 stages. Local relapse was 64% and the 3-year disease-free survival rate was 23% in 39 patients with tongue extension treated with external irradiation alone, versus 33 and 43% respectively for 90 patients with no tongue extension. The increase of lymph node metastases or neck recurrences was not related to tongue extension. In 15 patients with tongue extension, treated with external radiation plus brachytherapy, the local relapse was 40% and the 3-year survival rate 60%. External irradiation plus brachytherapy was significantly related to lower local relapse and increased survival rate compared to external irradiation alone in cancer of the tonsil with tongue extension. The combined modality was not associated with increased risk of radiation complications.
- Research Organization:
- Hospital Pereira Rossell, Montevideo, France
- OSTI ID:
- 7132895
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 10
- Country of Publication:
- United States
- Language:
- English
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62 RADIOLOGY AND NUCLEAR MEDICINE
CARCINOMAS
RADIOTHERAPY
PHARYNX
SIDE EFFECTS
LYMPHATIC SYSTEM
PATIENTS
SURVIVAL TIME
TONGUE
BODY
DIGESTIVE SYSTEM
DISEASES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORAL CAVITY
ORGANS
RADIOLOGY
RESPIRATORY SYSTEM
THERAPY
560151* - Radiation Effects on Animals- Man
550603 - Medicine- External Radiation in Therapy- (1980-)