Physiologic tomography (PT): a new approach to in vivo measure of metabolism and physiological function. [Diagnostic effectiveness of positron transaxial tomography]
Factors involved in the diagnostic effectiveness of computed-radionuclide tomography are discussed. Each of the above factors is discussed with physical and instrumentation aspects exemplified by a positron transaxial tomograph, a generalized physiological model presented to demonstrate use of quantitative autoradiographic models for in vivo tomography and tomographic studies of human volunteers and patients using /sup 13/NH/sub 3/, /sup 11/CO and /sup 11/C-glucose to image blood perfusion, blood volume and metabolism in brain (/sup 68/Ga for blood brain barrier) and heart, and /sup 11/C-palmitic acid studies of dogs with myocardial infarction. These studies illustrate ability to implement quantitative studies of hemodynamics and metabolism; mathematical and physical factors are calculated to illustrate advantages and disadvantages of a true 3-dimensional positron tomograph.
- Research Organization:
- California Univ., Los Angeles (USA). Lab. of Nuclear Medicine and Radiation Biology
- DOE Contract Number:
- E(04-1)-GEN-12
- OSTI ID:
- 7126182
- Report Number(s):
- UCLA-12-1098; CONF-761060-2; IAEA-SM-210/303; TRN: 77-004969
- Resource Relation:
- Conference: IAEA symposium on medical radionuclide imaging, Los Angeles, CA, USA, 25 Oct 1976
- Country of Publication:
- United States
- Language:
- English
Similar Records
Transaxial tomographic imaging of canine myocardium with /sup 11/C-palmitic acid
Emission computed tomography: a new technique for the quantitative physiologic study of brain and heart in vivo
Related Subjects
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
BRAIN
BLOOD FLOW
SCINTISCANNING
TOMOGRAPHY
HEART
HEMIC DISEASES
DIAGNOSTIC TECHNIQUES
METABOLIC DISEASES
CARBON 11
GALLIUM 68
LABELLED COMPOUNDS
NITROGEN 13
NUCLEAR MEDICINE
PATIENTS
POSITRON SOURCES
RADIONUCLIDE ADMINISTRATION
TISSUE DISTRIBUTION
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY
CARBON ISOTOPES
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
COUNTING TECHNIQUES
DISEASES
DISTRIBUTION
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
GALLIUM ISOTOPES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOTOPES
LIGHT NUCLEI
MEDICINE
MINUTES LIVING RADIOISOTOPES
NERVOUS SYSTEM
NITROGEN ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
ORGANS
PARTICLE SOURCES
RADIATION SOURCES
RADIOISOTOPE SCANNING
RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
440101 - Radiation Instrumentation- General Detectors or Monitors & Radiometric Instruments