1-/sup 14/C-n-hexadecane disposition in the spiny lobster, Panulirus argus and the American lobster, Homarus americanus
1-/sup 14/C-n-hexadecane, a model compound for the non-volatile aliphatic hydrocarbon components of crude oil, was administered by intrapericardial injection to the spiny lobster, Panulirus argus, and the clawed or American lobster, Homarus americanus. Experiments were conducted in Florida (spiny lobster) and Maine (American lobster). The animals were sacrificed at various times from 0.5 hr to 8 wks after administration of the dose. The tissues and fluids were analyzed for /sup 14/C content by digestion or catalytic oxidation and liquid scintillation counting. Selected tissues (hepatopancreas, tail muscle and hemolymph) were extracted with ethyl acetate to allow quantitation of the unmetabolized n-hexadecane by thin layer chromatography. n-Hexadecane-derived radioactivity was very persistent in both the spiny lobster (t1/2 = 4.6 wk) and the American lobster (t1/2 = 11.2 wk). In both lobsters, the hepatopancreas (HP) acquired the highest specific activity and the tail muscle had the longest half life for elimination from an individual tissue. Although hexadecane was metabolized more rapidly in the HP of the spiny lobster than in the HP of the American lobster, unmetabolized hexadecane persisted in the HPs of both species for at least 8 weeks after the dose (the longest time studied).
- Research Organization:
- National Institute of Environmental Health Sciences, St. Augustine, FL
- OSTI ID:
- 7080841
- Journal Information:
- J. Environ. Pathol., Toxicol. Oncol.; (United States), Vol. 5-6
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
02 PETROLEUM
HEXADECANE
TISSUE DISTRIBUTION
CARBON 14 COMPOUNDS
LOBSTERS
METABOLISM
TRACER TECHNIQUES
ALKANES
ANIMALS
AQUATIC ORGANISMS
ARTHROPODS
CRUSTACEANS
DECAPODS
DISTRIBUTION
HYDROCARBONS
INVERTEBRATES
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
ORGANIC COMPOUNDS
560300* - Chemicals Metabolism & Toxicology
020900 - Petroleum- Environmental Aspects