Responses to graded phytic acid in young Japanese quail

Conference · Wed Mar 05 00:00:00 EST 1986 · Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States)

OSTI ID:7022021

Fox, M R.S.; Tao, S H; Fry, Jr, B E; Phillippy, B Q; Lee, Y H; Johnston, M R

Graded levels of phytic acid (PA) were fed to day-old Japanese quail (Coturnix coturnix japonica) for 7 d to establish responses for evaluating effects of inositol tri-, tetra-, and pentaphosphates. Sodium phytate was added to supply 1.4, 2.8, 5.5, 8.4, 11.0, and 13.8 g PA/kg adequate casein-gelatin diet containing 20 mg Zn/kg. Eleven g phytic acid approximates that in diets containing defatted soy flour as the protein source. PA:Zn molar ratios were 7, 14, 27, 41, 54, and 68. The effects and graded response ranges (g PA/kg diet) were as follows: decreased body weight, 2.8-13.8; defective feathering, 1.4-5.5; decreased tibia Zn, 1.4-5.5; decreased tibia ash, 1.4-13.8; and decreased pancreas Zn, 1.4-5.5. The lowest level of PA produced marked decreases in tibia and pancreas Zn; thus the PA ranges can be extended to even lower levels. The effects of PA were reproducible between experiments and the mean values were reproducible except for tibia ash and liver Mn, which varied somewhat. There were no effects of PA on liver Zn and Mg, or on pancreas Fe and Mg; the effects on liver Fe and Cu, and tibia Fe and Mg were small and inconsistent. The responses to PA and the dose ranges provide a realistic basis for assessing the biological effects of other inositol phosphates that can be formed during food processing.

• Research Organization: Federal Drug Administration, Washington, DC
• OSTI ID: 7022021
• Report Number(s): CONF-8604222-
• Journal Information: Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States), Vol. 45:4; Conference: 70. annual meeting of the Federation of American Society for Experimental Biology, St. Louis, MO, USA, 13 Apr 1986
• Country of Publication: United States
• Language: English

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